Strain Name:
C57BL/6J-MtgxR6225Btlr
Stock Number:
044356-MU
Citation ID:
RRID:MMRRC_044356-MU
Other Names:
R6225 (G1)
Major Collection:

Gene Information

Nos1
Name: nitric oxide synthase 1, neuronal
Synonyms: nNOS, Nos-1, bNOS, NO, 2310005C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18125
HGNC: HGNC:7872
Homologene: 37327
Pds5b
Name: PDS5 cohesin associated factor B
Synonyms: Her-2 Tg, WAP-Her-2, AS3, Tg(Wap-ERBB2)229Wzw, Aprin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100710
Homologene: 41001
Serinc3
Name: serine incorporator 3
Synonyms: TMS-1, DIFF33, AIGP1, Tde1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 26943
Homologene: 38230
Ppat
Name: phosphoribosyl pyrophosphate amidotransferase
Synonyms: 5730454C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231327
HGNC: HGNC:9238
Homologene: 68272
Mtor
Name: mechanistic target of rapamycin kinase
Synonyms: 2610315D21Rik, FKBP-rapamycin-associated protein FRAP, Frap1, RAPT1, RAFT1, mechanistic target of rapamycin (serine/threonine kinase), flat
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56717
HGNC: HGNC:3942
Homologene: 3637
Morc3
Name: microrchidia 3
Synonyms: 1110051N18Rik, 1110051N18Rik, Zcwcc3, D16Jhu32e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 338467
Homologene: 32257
Rpl22
Name: ribosomal protein L22
Synonyms: 2700038K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 19934
Homologene: 37378
Tpx2
Name: TPX2, microtubule-associated
Synonyms: REPP86, 2610005B21Rik, p100, DIL2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 72119
HGNC: HGNC:1249
Homologene: 8107
Mettl3
Name: methyltransferase like 3
Synonyms: M6A, Spo8, 2310024F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 56335
Homologene: 10501
Mical3
Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Synonyms: C130040D16Rik, MICAL-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 194401
Homologene: 85288
Akap9
Name: A kinase (PRKA) anchor protein (yotiao) 9
Synonyms: mei2-5, G1-448-15, 5730481H23Rik, AKAP450, repro12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: FSA, Tweek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229227
Homologene: 52105
Zfp972
Name: zinc finger protein 972
Synonyms: C330013J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 78703
Nckap5l
Name: NCK-associated protein 5-like
Synonyms: C230021P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 380969
Homologene: 18924
Zzef1
Name: zinc finger, ZZ-type with EF hand domain 1
Synonyms: 8430405D05Rik, C130099L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 195018
Homologene: 9027
Slc25a16
Name: solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
Synonyms: ML7, HGT.1, 3110021G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 73132
Homologene: 21858
Pggt1b
Name: protein geranylgeranyltransferase type I, beta subunit
Synonyms: GGT1, BGG1, 2010207C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225467
VEGA: 18
HGNC: HGNC:8895
Homologene: 3685
Slitrk5
Name: SLIT and NTRK-like family, member 5
Synonyms: 2610019D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 75409
VEGA: 14
Homologene: 9193
Mrpl2
Name: mitochondrial ribosomal protein L2
Synonyms: MRP-L14, Rpml14, CGI-22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 27398
Homologene: 69198
Fstl3
Name: follistatin-like 3
Synonyms: Flrg, E030038F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 83554
HGNC: HGNC:3973
Homologene: 4280
Hhipl2
Name: hedgehog interacting protein-like 2
Synonyms: 4930507C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 78772
Homologene: 11690
Cops6
Name: COP9 signalosome subunit 6
Synonyms: COP9 complex S6, VIP/MOV34, Sgn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 26893
Homologene: 4977
Fam185a
Name: family with sequence similarity 185, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330050
Homologene: 51828
Lnpep
Name: leucyl/cystinyl aminopeptidase
Synonyms: 2010309L07Rik, 4732490P18Rik, IRAP, vp165, gp160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 240028
VEGA: 17
HGNC: HGNC:6656
Homologene: 21148
G2e3
Name: G2/M-phase specific E3 ubiquitin ligase
Synonyms: 6030408C04Rik, D930034K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217558
Homologene: 32362
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
Large2
Name: LARGE xylosyl- and glucuronyltransferase 2
Synonyms: 5730485C17Rik, Gyltl1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228366
Homologene: 27362
Chia1
Name: chitinase, acidic 1
Synonyms: YNL, Chia, AMCase, 2200003E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 81600
Homologene: 75168
Myo1g
Name: myosin IG
Synonyms: E430002D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 246177
Homologene: 27996
Proser3
Name: proline and serine rich 3
Synonyms: BC053749
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 333193
Homologene: 116064
Ahrr
Name: aryl-hydrocarbon receptor repressor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 11624
HGNC: HGNC:346
Homologene: 49215
Rnf135
Name: ring finger protein 135
Synonyms: 0610037N03Rik, MGC13061, U 2-3-0, 2410006N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71956
Homologene: 12427
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Slco1a1
Name: solute carrier organic anion transporter family, member 1a1
Synonyms: Slc21a1, Oatp1, Oatp1a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 28248
Homologene: 137261
Kcnj16
Name: potassium inwardly-rectifying channel, subfamily J, member 16
Synonyms: Kir5.1, 6430410F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16517
HGNC: HGNC:6262
Homologene: 23112
Olfr615
Name: olfactory receptor 615
Synonyms: MOR19-2, GA_x6K02T2PBJ9-6284902-6285843
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259084
Homologene: 17494
C4b
Name: complement component 4B (Chido blood group)
Synonyms: C4, Ss
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12268
Homologene: 36030
Cacna1i
Name: calcium channel, voltage-dependent, alpha 1I subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239556
HGNC: HGNC:1396
Homologene: 69331
Tmed6
Name: transmembrane p24 trafficking protein 6
Synonyms: 1810015P03Rik, 1810018I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 66269
Homologene: 11938
Olfr221
Name: olfactory receptor 221
Synonyms: GA_x6K02SYYB8M-929-258, MOR205-2, Olfr1514, GA_x6K02T2RJGY-959918-960853, MOR205-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258420
Homologene: 45823
D630003M21Rik
Name: RIKEN cDNA D630003M21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228846
Homologene: 18598
Mmut
Name: methylmalonyl-Coenzyme A mutase
Synonyms: D230010K02Rik, Mut
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17850
VEGA: 17
HGNC: HGNC:7526
Homologene: 20097
Daam2
Name: dishevelled associated activator of morphogenesis 2
Synonyms: 2310016D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 76441
VEGA: 17
Homologene: 69186
Adssl1
Name: adenylosuccinate synthetase like 1
Synonyms: Adss
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 11565
VEGA: 12
Homologene: 111992
Herc6
Name: hect domain and RLD 6
Synonyms: CEB1, 4930427L17Rik, Herc5, 1700121D12Rik, 2510038N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67138
Homologene: 70768
Kcnt2
Name: potassium channel, subfamily T, member 2
Synonyms: E330038N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240776
Homologene: 16121
Zfp267
Name: zinc finger protein 267
Synonyms: D3Ertd254e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 241944
Homologene: 117700
Gfra1
Name: glial cell line derived neurotrophic factor family receptor alpha 1
Synonyms: GDNFR-alpha, GFR alpha-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 14585
HGNC: HGNC:4243
Homologene: 3855
Mrc2
Name: mannose receptor, C type 2
Synonyms: Endo180, novel lectin, uPARAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17534
Homologene: 4408
Ssrp1
Name: structure specific recognition protein 1
Synonyms: Hmgox, Hmgi-rs3, T160, Hmg1-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20833
Homologene: 110735
P3h2
Name: prolyl 3-hydroxylase 2
Synonyms: Leprel1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 210530
Homologene: 10062
Olfr382
Name: olfactory receptor 382
Synonyms: GA_x6K02T2P1NL-3676608-3675670, MOR135-14, MOR135-31_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258435
Homologene: 17252
Phxr2
Name: per-hexamer repeat gene 2
Synonyms: SP28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Pnpt1
Name: polyribonucleotide nucleotidyltransferase 1
Synonyms: polynucleotide phosphorylase, 1200003F12Rik, PNPase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71701
Homologene: 12404
Zfp709
Name: zinc finger protein 709
Synonyms: GIOT-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 236193
Homologene: 136795
Scel
Name: sciellin
Synonyms: 9230114I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 64929
VEGA: 14
Homologene: 2850
Ace
Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Synonyms: CD143
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11421
HGNC: HGNC:2707
Homologene: 37351
Adh1
Name: alcohol dehydrogenase 1 (class I)
Synonyms: Adh1tl, class I alcohol dehydrogenase, Adh-1-t, Adh1-e, Adh-1, Adh-1t, Adh-1e, ADH-AA, Adh1-t
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 11522
Homologene: 73888
Tle6
Name: transducin-like enhancer of split 6
Synonyms: Grg6, 1810057E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 114606
Homologene: 11701
Ndufc2
Name: NADH:ubiquinone oxidoreductase subunit C2
Synonyms: 2010300P09Rik, 14.5b subunit of the NADH-ubiquinone dehydrogenase complex, G1, 1810004I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68197
HGNC: HGNC:7706
Homologene: 3344
B4galnt2
Name: beta-1,4-N-acetyl-galactosaminyl transferase 2
Synonyms: Galgt2, Dlb-1, Dlb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14422
Homologene: 7329
Olfr71
Name: olfactory receptor 71
Synonyms: MOR262-4, GA_x6K02T2N78B-16230286-16231224, mOR17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56015
Homologene: 10460
Fads3
Name: fatty acid desaturase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 60527
VEGA: 19
HGNC: HGNC:3576
Homologene: 11025
Pcdhb20
Name: protocadherin beta 20
Synonyms: PcdhbT, Pcdhb14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93891
HGNC: HGNC:8685
Homologene: 134303
Svs6
Name: seminal vesicle secretory protein 6
Synonyms: SVS VI, MSVSP99, Svp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20945
Homologene: 49347
Oxct1
Name: 3-oxoacid CoA transferase 1
Synonyms: 2610008O03Rik, Scot-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 67041
HGNC: HGNC:8527
Homologene: 377
Olfr180
Name: olfactory receptor 180
Synonyms: MOR184-9, MOR184-11P, Olfr1563-ps1, GA_x54KRFPKG5P-55134972-55134019, MOR184-11P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 258178
Homologene: 79337
Olfr1148
Name: olfactory receptor 1148
Synonyms: MOR264-7, GA_x6K02T2Q125-49334566-49335510
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258220
Homologene: 79465
Thoc3
Name: THO complex 3
Synonyms: 2410044K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 73666
Homologene: 12505
Vmn2r31
Name: vomeronasal 2, receptor 31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100042591
Homologene: 113703
Tas2r130
Name: taste receptor, type 2, member 130
Synonyms: STC 7-4, T2R30, Tas2r30, mt2r42
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 387355
Homologene: 41536
Glrx2
Name: glutaredoxin 2 (thioltransferase)
Synonyms: 1700010P22Rik, Grx2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 69367
Homologene: 41098
Olfr1264
Name: olfactory receptor 1264
Synonyms: GA_x6K02T2Q125-51454183-51453257, MOR236-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258206
Homologene: 66365
Smok3c
Name: sperm motility kinase 3C
Synonyms: EG622486
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 622486
Homologene: 128738
Gm10100
Name: predicted gene 10100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 100502953
VEGA: 10
Homologene: 135713
Gm43302
Name: predicted gene 43302
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
Gm6569
Name: predicted gene 6569
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 102634429
Homologene: 139259
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 140,426,923 bp
  • T to A, chromosome 1 at 143,745,383 bp
  • T to A, chromosome 1 at 183,428,551 bp
  • A to G, chromosome 2 at 85,042,814 bp
  • A to G, chromosome 2 at 87,833,317 bp
  • A to G, chromosome 2 at 90,021,229 bp
  • A to G, chromosome 2 at 92,366,480 bp
  • A to T, chromosome 2 at 125,330,543 bp
  • A to G, chromosome 2 at 152,876,628 bp
  • A to T, chromosome 2 at 158,217,401 bp
  • A to G, chromosome 2 at 163,627,879 bp
  • A to G, chromosome 2 at 164,317,485 bp
  • A to T, chromosome 2 at 177,907,324 bp
  • T to C, chromosome 3 at 36,166,203 bp
  • T to C, chromosome 3 at 36,948,304 bp
  • T to C, chromosome 3 at 106,130,897 bp
  • T to C, chromosome 3 at 138,289,804 bp
  • T to C, chromosome 4 at 43,705,698 bp
  • T to A, chromosome 4 at 148,521,337 bp
  • C to T, chromosome 4 at 152,330,079 bp
  • T to C, chromosome 5 at 3,962,105 bp
  • T to C, chromosome 5 at 21,425,556 bp
  • T to C, chromosome 5 at 76,922,355 bp
  • T to A, chromosome 5 at 105,277,739 bp
  • T to A, chromosome 5 at 117,912,852 bp
  • T to C, chromosome 5 at 138,065,052 bp
  • T to C, chromosome 5 at 138,161,411 bp
  • T to G, chromosome 5 at 150,746,618 bp
  • G to T, chromosome 6 at 57,662,154 bp
  • C to T, chromosome 6 at 120,958,723 bp
  • TCATTTC to T, chromosome 6 at 131,630,584 bp
  • A to T, chromosome 6 at 141,924,489 bp
  • T to A, chromosome 7 at 7,394,639 bp
  • T to C, chromosome 7 at 30,543,728 bp
  • C to T, chromosome 7 at 46,249,034 bp
  • A to G, chromosome 7 at 97,406,892 bp
  • A to T, chromosome 7 at 103,561,282 bp
  • TCGACG to TCG, chromosome 8 at 71,890,708 bp
  • A to G, chromosome 8 at 107,061,739 bp
  • C to A, chromosome 10 at 62,928,323 bp
  • G to T, chromosome 10 at 77,726,664 bp
  • A to G, chromosome 10 at 79,780,009 bp
  • A to G, chromosome 10 at 81,592,766 bp
  • A to G, chromosome 10 at 99,126,181 bp
  • A to T, chromosome 11 at 6,519,168 bp
  • T to C, chromosome 11 at 29,145,469 bp
  • G to A, chromosome 11 at 72,869,805 bp
  • T to C, chromosome 11 at 73,517,005 bp
  • A to C, chromosome 11 at 80,189,227 bp
  • A to G, chromosome 11 at 95,868,442 bp
  • A to G, chromosome 11 at 105,346,820 bp
  • A to G, chromosome 11 at 105,979,619 bp
  • A to T, chromosome 11 at 111,025,552 bp
  • A to G, chromosome 12 at 51,369,136 bp
  • A to C, chromosome 12 at 112,634,403 bp
  • T to C, chromosome 13 at 54,467,972 bp
  • A to G, chromosome 13 at 74,222,912 bp
  • C to A, chromosome 14 at 52,035,368 bp
  • T to C, chromosome 14 at 52,296,758 bp
  • T to C, chromosome 14 at 103,591,984 bp
  • GACTAC to GACTACTAC, chromosome 14 at 111,679,816 bp
  • T to C, chromosome 15 at 4,035,330 bp
  • A to G, chromosome 15 at 73,839,791 bp
  • A to G, chromosome 15 at 80,321,226 bp
  • C to A, chromosome 15 at 99,428,024 bp
  • T to A, chromosome 16 at 25,965,743 bp
  • T to C, chromosome 16 at 58,916,182 bp
  • C to A, chromosome 16 at 93,845,194 bp
  • T to C, chromosome 17 at 17,578,983 bp
  • C to A, chromosome 17 at 34,738,874 bp
  • T to A, chromosome 17 at 40,938,731 bp
  • T to C, chromosome 17 at 46,649,909 bp
  • T to C, chromosome 17 at 49,494,439 bp
  • A to G, chromosome 18 at 37,504,994 bp
  • A to G, chromosome 18 at 46,274,607 bp
  • A to G, chromosome 19 at 10,041,838 bp
  • G to A, chromosome 19 at 58,238,398 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6225 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044356-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.