Strain Name:
C57BL/6J-MtgxR6240Btlr
Stock Number:
044364-MU
Citation ID:
RRID:MMRRC_044364-MU
Other Names:
R6240 (G1)
Major Collection:

Gene Information

Cdc25a
Name: cell division cycle 25A
Synonyms: D9Ertd393e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12530
HGNC: HGNC:1725
Homologene: 1355
Tnpo1
Name: transportin 1
Synonyms: D13Ertd688e, Kpnb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238799
HGNC: HGNC:6401
Homologene: 5358
Pcf11
Name: PCF11 cleavage and polyadenylation factor subunit
Synonyms: 5730417B17Rik, 2500001H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74737
Homologene: 32282
Pepd
Name: peptidase D
Synonyms: Pep-4, peptidase D, Pep4, dal
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18624
HGNC: HGNC:8840
Homologene: 239
Arhgef18
Name: rho/rac guanine nucleotide exchange factor (GEF) 18
Synonyms: D030053O22Rik, A430078G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 319493
Homologene: 32254
Morc3
Name: microrchidia 3
Synonyms: 1110051N18Rik, D16Jhu32e, 1110051N18Rik, Zcwcc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 338467
Homologene: 32257
Psmd3
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
Synonyms: AntP91a, Psd3, Tstap91a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22123
HGNC: HGNC:9560
Homologene: 2102
Arid1a
Name: AT rich interactive domain 1A (SWI-like)
Synonyms: Osa1, 1110030E03Rik, Smarcf1, BAF250a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 93760
Homologene: 21216
Tcf12
Name: transcription factor 12
Synonyms: ME1, ALF1, HEB, HTF4, HTF-4, REB, bHLHb20, HEBAlt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21406
Homologene: 40774
Cad
Name: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Synonyms: 2410008J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69719
HGNC: HGNC:1424
Homologene: 1412
Tdrd3
Name: tudor domain containing 3
Synonyms: 4732418C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219249
Homologene: 12771
Clmp
Name: CXADR-like membrane protein
Synonyms: 9030425E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71566
Homologene: 11705
Ahi1
Name: Abelson helper integration site 1
Synonyms: Ahi-1, 1700015F03Rik, D10Bwg0629e, Jouberin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 52906
VEGA: 10
Homologene: 9762
Icam5
Name: intercellular adhesion molecule 5, telencephalin
Synonyms: CD50, Tlcn, TLN, Icam3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 15898
VEGA: 9
HGNC: HGNC:5348
Homologene: 2447
Robo2
Name: roundabout guidance receptor 2
Synonyms: 9430089E08Rik, D230004I22Rik, 2600013A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268902
Homologene: 43188
Fzd3
Name: frizzled class receptor 3
Synonyms: Fz3, D930050A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 14365
HGNC: HGNC:4041
Homologene: 23004
Plk2
Name: polo like kinase 2
Synonyms: Snk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20620
VEGA: 13
Homologene: 21317
Olfr734
Name: olfactory receptor 734
Synonyms: GA_x6K02T2PMLR-6013665-6012724, MOR242-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258658
Homologene: 51759
Adamts12
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239337
VEGA: 15
Homologene: 12808
E4f1
Name: E4F transcription factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13560
VEGA: 17
HGNC: HGNC:3121
Homologene: 3259
Nudt9
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 9
Synonyms: 1190002C07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74167
HGNC: HGNC:8056
Homologene: 11435
Asxl3
Name: ASXL transcriptional regulator 3
Synonyms: LOC381127, D930044O18Rik, D430002O22Rik, C230079D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 211961
Homologene: 19371
Smarcc2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
Synonyms: 5930405J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 68094
VEGA: 10
Homologene: 2312
Kcnk2
Name: potassium channel, subfamily K, member 2
Synonyms: TREK-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16526
HGNC: HGNC:6277
Homologene: 7794
Epha5
Name: Eph receptor A5
Synonyms: Cek7, bsk, Els1, Rek7, Hek7, Ehk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13839
HGNC: HGNC:3389
Homologene: 55824
Myo16
Name: myosin XVI
Synonyms: C230040D10Rik, Nyap3, BM140241
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244281
Homologene: 34710
Pcdh7
Name: protocadherin 7
Synonyms: BH-protocadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54216
HGNC: HGNC:8659
Homologene: 36101
Vmn2r6
Name: vomeronasal 2, receptor 6
Synonyms: EG620718, EG667069
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 667069
Homologene: 129754
Hnmt
Name: histamine N-methyltransferase
Synonyms: 1500031F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 140483
HGNC: HGNC:5028
Homologene: 5032
9930021J03Rik
Name: RIKEN cDNA 9930021J03 gene
Synonyms: Gm9832
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240613
Homologene: 19046
Mroh2b
Name: maestro heat-like repeat family member 2B
Synonyms: 4930455B06Rik, Heatr7b2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223825
VEGA: 15
Homologene: 128807
Dscam
Name: DS cell adhesion molecule
Synonyms: 4932410A21Rik, Down syndrome cell adhesion molecule
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13508
HGNC: HGNC:3039
Homologene: 74393
Srgap1
Name: SLIT-ROBO Rho GTPase activating protein 1
Synonyms: 4930572H05Rik, Arhgap13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 117600
Homologene: 56898
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: DY6, 2310047C17Rik, 1110004P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Tdrd1
Name: tudor domain containing 1
Synonyms: MTR-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 83561
Homologene: 12850
Olfr1216
Name: olfactory receptor 1216
Synonyms: GA_x6K02T2Q125-50494588-50493653, MOR233-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258895
Homologene: 74241
Glyctk
Name: glycerate kinase
Synonyms: 6230410P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235582
Homologene: 14738
Zfp628
Name: zinc finger protein 628
Synonyms: Zec
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232816
Homologene: 72200
Adgrg3
Name: adhesion G protein-coupled receptor G3
Synonyms: Pb99, A030001G24Rik, Gpr97
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 54672
Homologene: 18129
Adamts1
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
Synonyms: ADAM-TS1, METH1, METH-1, ADAMTS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 11504
HGNC: HGNC:217
Homologene: 21381
Dlg5
Name: discs large MAGUK scaffold protein 5
Synonyms: 4933429D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71228
HGNC: HGNC:2904
Homologene: 3486
Olfr1340
Name: olfactory receptor 1340
Synonyms: GA_x6K02T2QD9B-18823451-18822504, MOR258-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 258301
Homologene: 122779
B3glct
Name: beta-3-glucosyltransferase
Synonyms: LOC381694, B3galtl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381694
Homologene: 14978
Zfp872
Name: zinc finger protein 872
Synonyms: 9530015I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 619310
Tmem63c
Name: transmembrane protein 63c
Synonyms: 9330187M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217733
Homologene: 33129
Olfr814
Name: olfactory receptor 814
Synonyms: GA_x6K02T2PULF-11553313-11552381, MOR113-5, MOR113-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 259165
Homologene: 133585
Cdh18
Name: cadherin 18
Synonyms: B230220E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 320865
HGNC: HGNC:1757
Homologene: 55858
Mob3a
Name: MOB kinase activator 3A
Synonyms: 5330417K06Rik, Mobkl2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 208228
VEGA: 10
Homologene: 41587
Prag1
Name: PEAK1 related kinase activating pseudokinase 1
Synonyms: NACK, D8Ertd82e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244418
Homologene: 18256
Gm8765
Name: predicted gene 8765
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 667693
Homologene: 134512
Gm10382
Name: predicted gene 10382
Synonyms: EG639281
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
4930578I06Rik
Name: RIKEN cDNA 4930578I06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 67750
VEGA: 14
Homologene: 49859
Ptgs1
Name: prostaglandin-endoperoxide synthase 1
Synonyms: Cox-1, cyclooxygenase 1, Pghs1, COX1, Cox-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19224
HGNC: HGNC:9604
Homologene: 743
Nat1
Name: N-acetyl transferase 1
Synonyms: Nat-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 17960
Homologene: 115468
Vmn1r1
Name: vomeronasal 1 receptor 1
Synonyms: Gm6628
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 625823
Homologene: 83459
Vmn1r203
Name: vomeronasal 1 receptor 203
Synonyms: V1rh11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171270
Homologene: 110880
Jazf1
Name: JAZF zinc finger 1
Synonyms: Tip27, Jaz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 231986
Homologene: 18291
Hoxc10
Name: homeobox C10
Synonyms: Hox-3.6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 209448
HGNC: HGNC:5122
Homologene: 9680
Olfr1205
Name: olfactory receptor 1205
Synonyms: GA_x6K02T2Q125-50336588-50337313, GA_x6K02T2Q125-50304328-50305251, MOR230-1, MOR230-3, Olfr1203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258898
Homologene: 81567
Kcnmb2
Name: potassium large conductance calcium-activated channel, subfamily M, beta member 2
Synonyms: 3110031N04Rik, 2700049B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72413
HGNC: HGNC:6286
Homologene: 4257
Rab18
Name: RAB18, member RAS oncogene family
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 19330
VEGA: 18
Homologene: 40765
Tmem255b
Name: transmembrane protein 255B
Synonyms: LOC272465, Fam70b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 272465
Homologene: 18804
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 182,157,621 bp
  • A to G, chromosome 1 at 189,242,982 bp
  • T to A, chromosome 2 at 24,014,269 bp
  • G to A, chromosome 2 at 36,237,285 bp
  • A to G, chromosome 2 at 88,831,363 bp
  • A to G, chromosome 2 at 89,013,626 bp
  • C to T, chromosome 3 at 32,181,896 bp
  • T to A, chromosome 3 at 64,556,805 bp
  • A to G, chromosome 4 at 118,726,471 bp
  • A to G, chromosome 4 at 133,680,686 bp
  • T to A, chromosome 5 at 31,072,978 bp
  • T to C, chromosome 5 at 57,721,362 bp
  • G to C, chromosome 5 at 84,117,579 bp
  • T to C, chromosome 5 at 104,047,089 bp
  • G to A, chromosome 5 at 125,389,596 bp
  • A to G, chromosome 5 at 149,726,788 bp
  • A to T, chromosome 6 at 52,777,552 bp
  • A to G, chromosome 7 at 4,919,849 bp
  • A to G, chromosome 7 at 35,021,751 bp
  • T to A, chromosome 7 at 92,646,502 bp
  • G to A, chromosome 8 at 3,439,658 bp
  • A to T, chromosome 8 at 10,370,930 bp
  • A to G, chromosome 8 at 13,454,216 bp
  • T to C, chromosome 8 at 36,103,352 bp
  • A to T, chromosome 8 at 67,491,702 bp
  • A to G, chromosome 8 at 95,039,916 bp
  • T to A, chromosome 9 at 21,033,158 bp
  • A to G, chromosome 9 at 22,199,884 bp
  • A to G, chromosome 9 at 40,782,411 bp
  • T to A, chromosome 9 at 71,944,016 bp
  • A to T, chromosome 9 at 106,156,262 bp
  • A to G, chromosome 9 at 109,884,158 bp
  • A to G, chromosome 10 at 20,977,081 bp
  • C to G, chromosome 10 at 80,689,864 bp
  • A to G, chromosome 10 at 122,047,156 bp
  • C to T, chromosome 10 at 128,488,024 bp
  • C to A, chromosome 10 at 129,874,677 bp
  • A to G, chromosome 11 at 98,693,653 bp
  • A to T, chromosome 12 at 87,076,405 bp
  • A to G, chromosome 13 at 22,524,729 bp
  • G to A, chromosome 13 at 50,701,417 bp
  • T to C, chromosome 13 at 98,863,829 bp
  • T to A, chromosome 13 at 110,399,474 bp
  • T to A, chromosome 13 at 110,400,034 bp
  • A to T, chromosome 14 at 24,149,528 bp
  • A to G, chromosome 14 at 50,320,586 bp
  • C to A, chromosome 14 at 63,986,252 bp
  • T to C, chromosome 14 at 65,209,855 bp
  • T to A, chromosome 14 at 87,505,886 bp
  • A to T, chromosome 15 at 4,934,644 bp
  • A to T, chromosome 15 at 11,285,958 bp
  • A to G, chromosome 15 at 23,226,936 bp
  • T to A, chromosome 15 at 102,970,830 bp
  • G to A, chromosome 16 at 73,982,139 bp
  • G to A, chromosome 16 at 85,802,157 bp
  • C to G, chromosome 16 at 93,862,684 bp
  • G to A, chromosome 16 at 96,619,502 bp
  • A to G, chromosome 17 at 24,444,582 bp
  • T to C, chromosome 18 at 6,784,635 bp
  • C to T, chromosome 18 at 22,465,508 bp
  • A to T, chromosome 19 at 9,013,583 bp
  • A to T, chromosome 19 at 29,717,240 bp
  • T to C, chromosome 19 at 56,841,335 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6240 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044364-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.