Strain Name:
C57BL/6J-MtgxR6257Btlr
Stock Number:
044374-MU
Citation ID:
RRID:MMRRC_044374-MU
Other Names:
R6257 (G1)
Major Collection:

Gene Information

Dntt
Name: deoxynucleotidyltransferase, terminal
Synonyms: Tdt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 21673
VEGA: 19
HGNC: HGNC:2983
Homologene: 3014
Ptprz1
Name: protein tyrosine phosphatase, receptor type Z, polypeptide 1
Synonyms: DSD-1-PG, phosphacan, PTPzeta, PTPbeta, Rptpbeta, Ptpz, Ptprz, RPTPz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Septin4
Name: septin 4
Synonyms: cell division control-related protein 2b, Pnutl2, Bh5, septin H5, ARTS, Sept4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18952
HGNC: HGNC:9165
Homologene: 6107
En1
Name: engrailed 1
Synonyms: En-1, Mo-en.1, engrailed-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13798
HGNC: HGNC:3342
Homologene: 50663
Runx1
Name: runt related transcription factor 1
Synonyms: AML1, Pebp2a2, runt domain, alpha subunit 2, Cbfa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12394
Homologene: 1331
Erbb4
Name: erb-b2 receptor tyrosine kinase 4
Synonyms: ErbB4, Her4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13869
HGNC: HGNC:3432
Homologene: 21084
Nup155
Name: nucleoporin 155
Synonyms: D930027M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 170762
VEGA: 15
HGNC: HGNC:8063
Homologene: 43155
Ncoa7
Name: nuclear receptor coactivator 7
Synonyms: 9030406N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 211329
VEGA: 10
Homologene: 65245
Chd1
Name: chromodomain helicase DNA binding protein 1
Synonyms: 4930525N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12648
HGNC: HGNC:1915
Homologene: 68174
Nf1
Name: neurofibromin 1
Synonyms: neurofibromin, Nf-1, Dsk9, Mhdadsk9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Ltn1
Name: listerin E3 ubiquitin protein ligase 1
Synonyms: 4930528H02Rik, Zfp294, Listerin, Rnf160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 78913
VEGA: 16
Homologene: 32272
Erbin
Name: Erbb2 interacting protein
Synonyms: 1700028E05Rik, Erbin, Erbb2ip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 59079
Homologene: 41282
Aspm
Name: abnormal spindle microtubule assembly
Synonyms: Sha1, Aspm, D330028K02Rik, MCPH5, Calmbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12316
Homologene: 7650
Ubr7
Name: ubiquitin protein ligase E3 component n-recognin 7 (putative)
Synonyms: 5730410I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66622
VEGA: 12
Homologene: 11998
Os9
Name: amplified in osteosarcoma
Synonyms: 4632413K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216440
VEGA: 10
Homologene: 31409
Smtnl2
Name: smoothelin-like 2
Synonyms: D130058I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 276829
Homologene: 82367
Phldb1
Name: pleckstrin homology like domain, family B, member 1
Synonyms: LL5A, D330037A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102693
Homologene: 15903
Cftr
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12638
HGNC: HGNC:1884
Homologene: 55465
Grid2ip
Name: glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
Synonyms: delphilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 170935
Homologene: 15781
Trak1
Name: trafficking protein, kinesin binding 1
Synonyms: 2310001H13Rik, hyrt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67095
Homologene: 25103
Abcf1
Name: ATP-binding cassette, sub-family F (GCN20), member 1
Synonyms: Abc50, D17Wsu166e, GCN20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224742
HGNC: HGNC:70
Homologene: 849
Dars2
Name: aspartyl-tRNA synthetase 2 (mitochondrial)
Synonyms: 5830468K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226539
Homologene: 7093
St3gal3
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 3
Synonyms: ST3Gal III, Siat3, Siat6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 20441
Homologene: 7539
Cd164l2
Name: CD164 sialomucin-like 2
Synonyms: 2310047N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69655
Homologene: 19231
Lhfpl3
Name: lipoma HMGIC fusion partner-like 3
Synonyms: A930031L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269629
HGNC: HGNC:6589
Homologene: 26732
Rbl2
Name: RB transcriptional corepressor like 2
Synonyms: Rb2, p130, retinoblastoma-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 19651
HGNC: HGNC:9894
Homologene: 4098
Casp8ap2
Name: caspase 8 associated protein 2
Synonyms: D4Ertd659e, FLASH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 26885
HGNC: HGNC:1510
Homologene: 8066
Noc3l
Name: NOC3 like DNA replication regulator
Synonyms: Fad24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 57753
VEGA: 19
Homologene: 39642
Tubgcp3
Name: tubulin, gamma complex associated protein 3
Synonyms: Spc98p, GCP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 259279
Homologene: 4609
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 171395
Homologene: 51376
Prkcb
Name: protein kinase C, beta
Synonyms: Pkcb, A130082F03Rik, PKC-Beta, Prkcb2, Prkcb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18751
HGNC: HGNC:9395
Homologene: 56424
Tgfb3
Name: transforming growth factor, beta 3
Synonyms: Tgfb-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 21809
VEGA: 12
Homologene: 2433
Nacc2
Name: nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
Synonyms: 0610020I02Rik, C030048H19Rik, Btbd14a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67991
Homologene: 75239
Maml2
Name: mastermind like transcriptional coactivator 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270118
Homologene: 134147
Ksr2
Name: kinase suppressor of ras 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 333050
Homologene: 45469
Lama2
Name: laminin, alpha 2
Synonyms: merosin, mer
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Adamts6
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
Synonyms: ADAM-TS6, A930019D11Rik, b2b2228Clo, b2b2187.1Clo, b2b2182Clo, b2b2029Clo, b2b1879.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 108154
VEGA: 13
HGNC: HGNC:222
Homologene: 82573
Fat2
Name: FAT atypical cadherin 2
Synonyms: LOC245827, mKIAA0811, Fath2, EMI2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Fcsk
Name: fucose kinase
Synonyms: L-fucose kinase, 1110046B12Rik, Fuk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234730
Homologene: 15452
Olfr406
Name: olfactory receptor 406
Synonyms: GA_x6K02T2P1NL-4415162-4416133, MOR133-1, Olfr406-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258181
HGNC: HGNC:8222
Dock10
Name: dedicator of cytokinesis 10
Synonyms: Jr5, Jr4, 9330153B10Rik, ZIZ3, A630054M16Rik, Zizimin3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210293
Homologene: 45952
Ccser1
Name: coiled-coil serine rich 1
Synonyms: 6230405M12Rik, C130092O11Rik, Fam190a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232035
Homologene: 28086
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Dscam
Name: DS cell adhesion molecule
Synonyms: 4932410A21Rik, Down syndrome cell adhesion molecule
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13508
HGNC: HGNC:3039
Homologene: 74393
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Adamts2
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
Synonyms: ADAM-TS2, hPCPNI, a disintegrin and metalloproteinase with thrombospondin repeats, procollagen N-proteinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216725
HGNC: HGNC:218
Homologene: 8597
Cpd
Name: carboxypeptidase D
Synonyms: D830034L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12874
HGNC: HGNC:2301
Homologene: 999
Oas3
Name: 2'-5' oligoadenylate synthetase 3
Synonyms: 2'-5' oligoadenylate synthetase-like 10, Oasl10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 246727
HGNC: HGNC:8088
Homologene: 4510
Adgre4
Name: adhesion G protein-coupled receptor E4
Synonyms: EGF-TM7, D17Ertd479e, FIRE, Gpr127, Emr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 52614
VEGA: 17
Homologene: 64640
Defb26
Name: defensin beta 26
Synonyms: EG654457
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 654457
Homologene: 86850
Tmbim1
Name: transmembrane BAX inhibitor motif containing 1
Synonyms: 2310061B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 69660
Homologene: 36404
Thsd7a
Name: thrombospondin, type I, domain containing 7A
Synonyms: LOC330267
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330267
Homologene: 46582
Vmn2r79
Name: vomeronasal 2, receptor 79
Synonyms: EG621430
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 621430
Homologene: 115466
Tmprss15
Name: transmembrane protease, serine 15
Synonyms: enteropeptidase, enterokinase, A130097D21Rik, Prss7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19146
HGNC: HGNC:9490
Homologene: 2075
Ccdc13
Name: coiled-coil domain containing 13
Synonyms: 2900041A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100502861
Homologene: 87213
Ces1d
Name: carboxylesterase 1D
Synonyms: TGH, Ces3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 104158
HGNC: HGNC:1863
Homologene: 35606
Cebpz
Name: CCAAT/enhancer binding protein zeta
Synonyms: Cbf, CBF2, Cebpa-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12607
VEGA: 17
Homologene: 4210
H2-T24
Name: histocompatibility 2, T region locus 24
Synonyms: H-2T24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15042
Homologene: 69019
Cacna2d4
Name: calcium channel, voltage-dependent, alpha 2/delta subunit 4
Synonyms: 5730412N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 319734
Homologene: 26544
Gmcl1
Name: germ cell-less, spermatogenesis associated 1
Synonyms: mglc-1, 2810049L19Rik, Gcl, Btbd13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 23885
Homologene: 8021
Trim30c
Name: tripartite motif-containing 30C
Synonyms: Trim30-2, Gm5598
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434219
Slc24a4
Name: solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
Synonyms: NCKX4, A930002M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238384
Homologene: 17798
Zfp536
Name: zinc finger protein 536
Synonyms: 9630010P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243937
Homologene: 8813
Cdk15
Name: cyclin-dependent kinase 15
Synonyms: Als2cr7, Pftk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 271697
Homologene: 64641
Atg16l2
Name: autophagy related 16-like 2 (S. cerevisiae)
Synonyms: 2410118P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73683
Homologene: 18981
Plppr4
Name: phospholipid phosphatase related 4
Synonyms: D3Bwg0562e, Lppr4, PRG-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229791
Homologene: 8895
Olfr315
Name: olfactory receptor 315
Synonyms: GA_x6K02T2NKPP-630272-629343, MOR278-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258531
Homologene: 128134
Tfpt
Name: TCF3 (E2A) fusion partner
Synonyms: Amida, FB1, 2400004F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69714
Homologene: 8349
Ocln
Name: occludin
Synonyms: Ocl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18260
HGNC: HGNC:8104
Homologene: 1905
Sri
Name: sorcin
Synonyms: Sor, 2210417O06Rik, 2900070H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 109552
Homologene: 37736
Tmem17
Name: transmembrane protein 17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103765
Homologene: 17795
Chil4
Name: chitinase-like 4
Synonyms: Ym2, Chi3l4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 104183
Homologene: 74931
Gm3443
Name: predicted gene 3443
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Cldn16
Name: claudin 16
Synonyms: PCLN1, claudin-16, paracellin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 114141
HGNC: HGNC:2037
Homologene: 4799
Gm6401
Name: predicted gene 6401
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Cst8
Name: cystatin 8 (cystatin-related epididymal spermatogenic)
Synonyms: Cst-rs1, Cres
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13012
HGNC: HGNC:2480
Homologene: 4011
Bcl6b
Name: B cell CLL/lymphoma 6, member B
Synonyms: Bazf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12029
HGNC: HGNC:1002
Homologene: 7243
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 59,257,105 bp
  • A to T, chromosome 1 at 68,396,273 bp
  • A to G, chromosome 1 at 74,293,066 bp
  • G to A, chromosome 1 at 80,503,696 bp
  • A to T, chromosome 1 at 120,603,907 bp
  • A to G, chromosome 1 at 139,482,053 bp
  • G to T, chromosome 1 at 161,041,828 bp
  • A to T, chromosome 2 at 26,060,408 bp
  • T to A, chromosome 2 at 40,596,969 bp
  • C to A, chromosome 2 at 148,805,445 bp
  • A to G, chromosome 2 at 152,507,940 bp
  • T to A, chromosome 3 at 106,204,096 bp
  • T to C, chromosome 3 at 117,322,579 bp
  • A to G, chromosome 4 at 32,641,364 bp
  • C to T, chromosome 4 at 118,107,678 bp
  • T to A, chromosome 4 at 133,221,034 bp
  • T to A, chromosome 5 at 8,059,596 bp
  • A to G, chromosome 5 at 22,746,559 bp
  • A to T, chromosome 5 at 117,414,844 bp
  • C to A, chromosome 5 at 120,761,135 bp
  • G to A, chromosome 5 at 143,380,429 bp
  • G to T, chromosome 6 at 12,408,988 bp
  • A to C, chromosome 6 at 18,282,501 bp
  • T to A, chromosome 6 at 22,959,640 bp
  • A to G, chromosome 6 at 61,373,962 bp
  • A to G, chromosome 6 at 62,379,785 bp
  • G to A, chromosome 6 at 86,700,641 bp
  • G to A, chromosome 6 at 119,281,619 bp
  • A to T, chromosome 7 at 3,629,567 bp
  • T to A, chromosome 7 at 37,480,405 bp
  • A to T, chromosome 7 at 87,002,570 bp
  • A to G, chromosome 7 at 101,301,895 bp
  • T to C, chromosome 7 at 104,390,168 bp
  • T to A, chromosome 7 at 122,568,163 bp
  • A to T, chromosome 8 at 12,649,835 bp
  • T to C, chromosome 8 at 91,115,678 bp
  • T to C, chromosome 8 at 93,166,397 bp
  • A to T, chromosome 8 at 110,890,545 bp
  • C to T, chromosome 9 at 13,620,426 bp
  • C to T, chromosome 9 at 44,696,140 bp
  • G to T, chromosome 9 at 121,367,224 bp
  • C to T, chromosome 9 at 121,446,755 bp
  • A to G, chromosome 9 at 121,798,909 bp
  • A to G, chromosome 10 at 26,986,899 bp
  • A to G, chromosome 10 at 30,694,177 bp
  • A to C, chromosome 10 at 127,119,137 bp
  • G to A, chromosome 11 at 8,942,195 bp
  • A to G, chromosome 11 at 22,512,297 bp
  • T to C, chromosome 11 at 50,775,326 bp
  • A to G, chromosome 11 at 55,262,581 bp
  • T to A, chromosome 11 at 58,779,003 bp
  • C to T, chromosome 11 at 70,226,052 bp
  • G to A, chromosome 11 at 72,401,399 bp
  • T to C, chromosome 11 at 74,270,007 bp
  • A to T, chromosome 11 at 76,812,670 bp
  • A to T, chromosome 11 at 79,549,491 bp
  • C to A, chromosome 11 at 87,590,349 bp
  • T to C, chromosome 12 at 86,077,841 bp
  • A to G, chromosome 12 at 102,254,510 bp
  • T to A, chromosome 12 at 102,765,840 bp
  • T to C, chromosome 13 at 100,539,509 bp
  • T to C, chromosome 13 at 103,862,288 bp
  • A to T, chromosome 13 at 104,462,282 bp
  • T to C, chromosome 14 at 41,967,871 bp
  • C to T, chromosome 15 at 8,150,798 bp
  • T to A, chromosome 16 at 26,481,330 bp
  • A to T, chromosome 16 at 78,972,225 bp
  • G to A, chromosome 16 at 87,411,774 bp
  • T to A, chromosome 16 at 92,695,911 bp
  • T to C, chromosome 16 at 96,673,714 bp
  • T to G, chromosome 17 at 15,730,203 bp
  • A to T, chromosome 17 at 35,961,182 bp
  • T to A, chromosome 17 at 36,014,682 bp
  • C to T, chromosome 17 at 55,802,133 bp
  • T to C, chromosome 17 at 78,935,832 bp
  • T to A, chromosome 18 at 32,013,415 bp
  • A to T, chromosome 19 at 21,555,711 bp
  • A to T, chromosome 19 at 38,795,905 bp
  • T to G, chromosome 19 at 41,053,062 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6257 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044374-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.