Strain Name:
C57BL/6J-MtgxR5236Btlr
Stock Number:
044393-MU
Citation ID:
RRID:MMRRC_044393-MU
Other Names:
R5236 (G1)
Major Collection:

Gene Information

Tln2
Name: talin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70549
VEGA: 9
Homologene: 56692
H2-DMa
Name: histocompatibility 2, class II, locus DMa
Synonyms: H2-M alpha, H2-Ma, H-2Ma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14998
HGNC: HGNC:4934
Homologene: 4464
Dst
Name: dystonin
Synonyms: Bpag1, Bpag, 2310001O04Rik, nmf339, BPAG1, BPAG1-n, bullous pemphigoid antigen 1, Macf2, nmf203, bullous pemphigoid antigen 1, athetoid, A830042E19Rik, ah
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: trabeculin alpha, Acf7, Aclp7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11426
Homologene: 136191
Zfp934
Name: zinc finger protein 934
Synonyms: 6720457D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 77117
VEGA: 13
Arid4b
Name: AT rich interactive domain 4B (RBP1-like)
Synonyms: SAP180, 6330417L24Rik, Rbp1l1, 6720480E17Rik, RBBP1L1, BRCAA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 94246
Homologene: 12847
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: D230004K18Rik, b2b1625.2Clo, Gp330, Megalin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Ppcdc
Name: phosphopantothenoylcysteine decarboxylase
Synonyms: 1810057I13Rik, 8430432M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66812
VEGA: 9
Homologene: 11049
Zranb3
Name: zinc finger, RAN-binding domain containing 3
Synonyms: 4933425L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226409
Homologene: 32770
E2f7
Name: E2F transcription factor 7
Synonyms: A630014C11Rik, D10Ertd739e, E2F7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 52679
Homologene: 18685
Zfp638
Name: zinc finger protein 638
Synonyms: Zfml, Np220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18139
Homologene: 7447
Agrn
Name: agrin
Synonyms: NMF380, Agrin, nmf380
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11603
HGNC: HGNC:329
Homologene: 27907
Trrap
Name: transformation/transcription domain-associated protein
Synonyms: transactivation/transformation-domain associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100683
Homologene: 39246
Lrp6
Name: low density lipoprotein receptor-related protein 6
Synonyms: Cd, ska26, skam26Jus, skax26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16974
HGNC: HGNC:6698
Homologene: 1747
Git2
Name: GIT ArfGAP 2
Synonyms: 9630056M03Rik, 1500036H07Rik, Cool associated tyrosine phosphorylated-2, B230104M05Rik, 5830420E16Rik, Cat-2, ARF GTPase activating protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26431
HGNC: HGNC:4273
Homologene: 41336
Opa3
Name: optic atrophy 3
Synonyms: LOC384570, LOC243868, D630048P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 403187
HGNC: HGNC:8142
Homologene: 57022
Kri1
Name: KRI1 homolog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 215194
Homologene: 133742
Melk
Name: maternal embryonic leucine zipper kinase
Synonyms: MPK38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 17279
Homologene: 32111
Mms22l
Name: MMS22-like, DNA repair protein
Synonyms: F730047E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 212377
Homologene: 18874
Hjurp
Name: Holliday junction recognition protein
Synonyms: C330011F01Rik, A730008H23Rik, 6430706D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381280
Homologene: 10184
Trpv4
Name: transient receptor potential cation channel, subfamily V, member 4
Synonyms: VRL-2, 0610033B08Rik, Trp12, OTRPC4, VROAC, VR-OAC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 63873
Homologene: 11003
Cdcp1
Name: CUB domain containing protein 1
Synonyms: 9030022E12Rik, E030027H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 109332
Homologene: 11276
Ctsa
Name: cathepsin A
Synonyms: Ppgb, PPCA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19025
HGNC: HGNC:9251
Homologene: 80163
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Rag2
Name: recombination activating gene 2
Synonyms: Rag-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19374
HGNC: HGNC:9832
Homologene: 7507
Htr7
Name: 5-hydroxytryptamine (serotonin) receptor 7
Synonyms: 5-HT7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 15566
HGNC: HGNC:5302
Homologene: 20244
Cdh23
Name: cadherin 23 (otocadherin)
Synonyms: mdfw, USH1D, ahl, nmf252, nmf181, nmf112, sals, bob, 4930542A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22295
Homologene: 11142
Fbxw9
Name: F-box and WD-40 domain protein 9
Synonyms: 1110017H11Rik, Fbw9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 68628
Homologene: 23598
Ttn
Name: titin
Synonyms: mdm, 2310036G12Rik, D830007G01Rik, shru, L56, 2310074I15Rik, 2310057K23Rik, connectin, D330041I19Rik, 1100001C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
BC067074
Name: cDNA sequence BC067074
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 408066
Tbx15
Name: T-box 15
Synonyms: Tbx14, Tbx8, de
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 21384
Homologene: 7967
Slc4a9
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 9
Synonyms: AE4, D630024F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240215
VEGA: 18
Homologene: 23732
Hrg
Name: histidine-rich glycoprotein
Synonyms: D16JH2, D18020
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 94175
HGNC: HGNC:5181
Homologene: 137650
Ccdc39
Name: coiled-coil domain containing 39
Synonyms: D3Ertd789e, 4921507O14Rik, b2b2025.1Clo, b2b1304Clo, prh, b2b1735Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 51938
Homologene: 12149
Unc79
Name: unc-79 homolog
Synonyms: Mlca3, 9030205A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217843
Homologene: 41397
Stpg2
Name: sperm tail PG rich repeat containing 2
Synonyms: B930007M17Rik, LOC381476
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 381476
Homologene: 52167
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: 2310047C17Rik, DY6, 1110004P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Plce1
Name: phospholipase C, epsilon 1
Synonyms: PLCepsilon, 4933403A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74055
Homologene: 9478
Rnf130
Name: ring finger protein 130
Synonyms: G1RP, G1RZFP, 2510042A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 59044
Homologene: 41267
Unc45b
Name: unc-45 myosin chaperone B
Synonyms: D230041A13Rik, UNC45, Cmya4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217012
Homologene: 14666
Cyp3a59
Name: cytochrome P450, family 3, subfamily a, polypeptide 59
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100041449
Homologene: 135775
Sult2a5
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5
Synonyms: EG434264, Gm15438
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434264
Homologene: 37741
Lcn2
Name: lipocalin 2
Synonyms: neu-related lipocalin, 24p3, NRL, NGAL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16819
HGNC: HGNC:6526
Homologene: 4064
Sgip1
Name: SH3-domain GRB2-like (endophilin) interacting protein 1
Synonyms: 3110007P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 73094
Homologene: 13001
Itpripl1
Name: inositol 1,4,5-triphosphate receptor interacting protein-like 1
Synonyms: 1700041B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 73338
Homologene: 77641
Slc23a2
Name: solute carrier family 23 (nucleobase transporters), member 2
Synonyms: YSPL3, Slc23a1, SVCT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 54338
Homologene: 68440
Olfr459
Name: olfactory receptor 459
Synonyms: GA_x6K02T2P3E9-5780974-5781915, MOR120-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258569
Homologene: 83448
9630041A04Rik
Name: RIKEN cDNA 9630041A04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Slc7a15
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 15
Synonyms: 2010001P20Rik, Arpat, 9030221C07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 328059
Homologene: 77627
Cyp4f17
Name: cytochrome P450, family 4, subfamily f, polypeptide 17
Synonyms: EG208285
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 208285
VEGA: 17
Homologene: 129713
Actl9
Name: actin-like 9
Synonyms: 1700029I08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 69481
Homologene: 77642
Vmn2r71
Name: vomeronasal 2, receptor 71
Synonyms: EG233445
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233445
Homologene: 115466
Mettl22
Name: methyltransferase like 22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239706
Homologene: 16619
Ndufaf7
Name: NADH:ubiquinone oxidoreductase complex assembly factor 7
Synonyms: 2410091C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 73694
VEGA: 17
Homologene: 12508
Krt27
Name: keratin 27
Synonyms: Krt1-c29, stpm, mIRSa3.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16675
Homologene: 7805
Olfr446
Name: olfactory receptor 446
Synonyms: MOR261-12, GA_x6K02T2P3E9-4632269-4631343
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258292
Homologene: 17179
Cmtm4
Name: CKLF-like MARVEL transmembrane domain containing 4
Synonyms: Cklfsf4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 97487
Homologene: 45211
Bin2
Name: bridging integrator 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 668218
HGNC: HGNC:1053
Homologene: 22965
Sprr2b
Name: small proline-rich protein 2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20756
1700024P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Pabpn1
Name: poly(A) binding protein, nuclear 1
Synonyms: poly(A) binding protein II, Pabp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 54196
HGNC: HGNC:8565
Homologene: 3412
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 34,164,417 bp
  • GT to GTT, chromosome 1 at 88,266,524 bp
  • A to G, chromosome 1 at 128,040,989 bp
  • A to T, chromosome 2 at 32,385,961 bp
  • T to C, chromosome 2 at 69,456,819 bp
  • G to A, chromosome 2 at 76,788,802 bp
  • A to T, chromosome 2 at 101,629,660 bp
  • A to T, chromosome 2 at 127,141,850 bp
  • T to A, chromosome 2 at 132,075,584 bp
  • G to A, chromosome 2 at 164,838,911 bp
  • T to C, chromosome 3 at 33,830,102 bp
  • G to A, chromosome 3 at 92,317,636 bp
  • A to T, chromosome 3 at 99,352,046 bp
  • A to T, chromosome 3 at 139,232,223 bp
  • A to G, chromosome 4 at 24,588,347 bp
  • G to A, chromosome 4 at 44,344,959 bp
  • T to G, chromosome 4 at 102,927,587 bp
  • T to C, chromosome 4 at 104,948,760 bp
  • T to C, chromosome 4 at 123,397,821 bp
  • A to T, chromosome 4 at 156,178,858 bp
  • A to C, chromosome 5 at 114,622,795 bp
  • T to A, chromosome 5 at 114,767,172 bp
  • A to G, chromosome 5 at 144,817,786 bp
  • A to G, chromosome 5 at 146,102,825 bp
  • C to A, chromosome 6 at 41,772,111 bp
  • A to C, chromosome 6 at 42,927,781 bp
  • G to T, chromosome 6 at 83,976,575 bp
  • T to C, chromosome 6 at 134,511,264 bp
  • A to T, chromosome 7 at 13,665,049 bp
  • A to G, chromosome 7 at 19,244,757 bp
  • A to T, chromosome 7 at 85,623,669 bp
  • A to G, chromosome 8 at 85,066,345 bp
  • G to C, chromosome 8 at 104,357,746 bp
  • T to C, chromosome 9 at 21,275,941 bp
  • A to C, chromosome 9 at 57,414,654 bp
  • T to A, chromosome 9 at 67,365,923 bp
  • T to A, chromosome 9 at 101,942,921 bp
  • A to T, chromosome 9 at 123,185,193 bp
  • A to G, chromosome 10 at 60,312,572 bp
  • C to T, chromosome 10 at 110,767,209 bp
  • C to T, chromosome 11 at 50,095,978 bp
  • T to A, chromosome 11 at 82,915,062 bp
  • A to C, chromosome 11 at 99,350,815 bp
  • C to T, chromosome 12 at 8,539,005 bp
  • T to A, chromosome 12 at 103,094,395 bp
  • A to G, chromosome 13 at 14,126,449 bp
  • A to T, chromosome 13 at 62,517,713 bp
  • A to G, chromosome 13 at 113,366,220 bp
  • T to A, chromosome 14 at 54,894,942 bp
  • T to C, chromosome 15 at 100,662,534 bp
  • T to A, chromosome 16 at 8,488,733 bp
  • T to C, chromosome 16 at 22,961,513 bp
  • T to C, chromosome 17 at 32,520,632 bp
  • T to C, chromosome 17 at 33,434,099 bp
  • T to A, chromosome 17 at 34,137,939 bp
  • T to C, chromosome 17 at 67,804,492 bp
  • T to C, chromosome 17 at 78,939,631 bp
  • A to G, chromosome 18 at 36,530,847 bp
  • A to G, chromosome 19 at 9,000,684 bp
  • A to T, chromosome 19 at 36,056,769 bp
  • A to C, chromosome 19 at 38,770,347 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5236 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044393-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.