Strain Name:
C57BL/6J-MtgxR5571Btlr
Stock Number:
044395-MU
Citation ID:
RRID:MMRRC_044395-MU
Other Names:
R5571 (G1)
Major Collection:

Gene Information

Tln2
Name: talin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 70549
VEGA: 9
Homologene: 56692
Dhrs3
Name: dehydrogenase/reductase (SDR family) member 3
Synonyms: retSDR1, Rsdr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 20148
Homologene: 20994
Hmgcr
Name: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Synonyms: 3-hydroxy-3-methylglutaryl-CoA reductase, HMG-CoAR, Red
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 15357
HGNC: HGNC:5006
Homologene: 30994
Ppp4r1
Name: protein phosphatase 4, regulatory subunit 1
Synonyms: 3110001J10Rik, Pp4r1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 70351
HGNC: HGNC:9320
Homologene: 81737
Wdr59
Name: WD repeat domain 59
Synonyms: 5430401O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 319481
Homologene: 38685
Atad5
Name: ATPase family, AAA domain containing 5
Synonyms: C130052G03Rik, LOC237877
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237877
Homologene: 32611
Zfhx3
Name: zinc finger homeobox 3
Synonyms: WBP9, Sci, A230102L03Rik, Atbf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Epb41
Name: erythrocyte membrane protein band 4.1
Synonyms: 4.1R, Elp1, Elp-1, D4Ertd442e, Epb4.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269587
HGNC: HGNC:3377
Homologene: 44324
Gapvd1
Name: GTPase activating protein and VPS9 domains 1
Synonyms: 4432404J10Rik, 2010005B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66691
Homologene: 32637
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: Murr2, A530081C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17847
Homologene: 40978
Ep300
Name: E1A binding protein p300
Synonyms: KAT3B, p300
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 328572
HGNC: HGNC:3373
Homologene: 1094
Unc13d
Name: unc-13 homolog D
Synonyms: Jinx, 2610108D09Rik, Munc13-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 70450
Homologene: 26714
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20191
VEGA: 13
Homologene: 37423
Oga
Name: O-GlcNAcase
Synonyms: 2810009A20Rik, Hy5, 4833427O07Rik, 5830447M11Rik, Mgea5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 76055
VEGA: 19
HGNC: HGNC:7056
Homologene: 8154
Cbln2
Name: cerebellin 2 precursor protein
Synonyms: 6330593N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 12405
HGNC: HGNC:1544
Homologene: 18203
Steap2
Name: six transmembrane epithelial antigen of prostate 2
Synonyms: 4921538B17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74051
Homologene: 17682
Neto2
Name: neuropilin (NRP) and tolloid (TLL)-like 2
Synonyms: 5530601C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74513
Homologene: 32387
Gmds
Name: GDP-mannose 4, 6-dehydratase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218138
HGNC: HGNC:4369
Homologene: 75968
Ube2d2a
Name: ubiquitin-conjugating enzyme E2D 2A
Synonyms: 1500034D03Rik, ubc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 56550
VEGA: 18
Homologene: 2506
Zcchc2
Name: zinc finger, CCHC domain containing 2
Synonyms: 9930114B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227449
Homologene: 9808
Taf6l
Name: TATA-box binding protein associated factor 6 like
Synonyms: 2810417N14Rik, PAF65A, C530024J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225895
Homologene: 4728
Tmprss2
Name: transmembrane protease, serine 2
Synonyms: D16Ertd61e, epitheliasin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 50528
VEGA: 16
Homologene: 4136
Bsph1
Name: binder of sperm protein homolog 1
Synonyms: LOC330470
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 330470
Homologene: 86818
Tbkbp1
Name: TBK1 binding protein 1
Synonyms: 3110043L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 73174
Homologene: 8820
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 329628
Homologene: 14377
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
5830411N06Rik
Name: RIKEN cDNA 5830411N06 gene
Synonyms: Scart2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244234
Homologene: 133218
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
9530053A07Rik
Name: RIKEN cDNA 9530053A07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 319482
Homologene: 130055
Olfr183
Name: olfactory receptor 183
Synonyms: GA_x54KRFPKG5P-55229158-55230087, MOR183-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 258478
Homologene: 27178
Mdm1
Name: transformed mouse 3T3 cell double minute 1
Synonyms: Mdm-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 17245
VEGA: 10
Homologene: 9692
Folh1
Name: folate hydrolase 1
Synonyms: prostate-specific membrane antigen, mopsm, glutamate carboxypeptidase II, GCP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 53320
HGNC: HGNC:3788
Homologene: 55826
Gp6
Name: glycoprotein 6 (platelet)
Synonyms: Gpvi, 9830166G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243816
Homologene: 9488
Tm2d3
Name: TM2 domain containing 3
Synonyms: 1110025I09Rik, 5930422O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68634
Homologene: 12275
Slc14a2
Name: solute carrier family 14 (urea transporter), member 2
Synonyms: UT-A3, UT-A5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 27411
VEGA: 18
Homologene: 5183
Fbxw24
Name: F-box and WD-40 domain protein 24
Synonyms: Gm5162
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 382106
Homologene: 110776
Fndc7
Name: fibronectin type III domain containing 7
Synonyms: E230011A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 320181
Homologene: 18551
Cntnap3
Name: contactin associated protein-like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 238680
VEGA: 13
Homologene: 129602
Ssrp1
Name: structure specific recognition protein 1
Synonyms: Hmgox, Hmgi-rs3, T160, Hmg1-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20833
Homologene: 110735
Vmn2r8
Name: vomeronasal 2, receptor 8
Synonyms: EG627479
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 627479
Homologene: 129606
Fbxw22
Name: F-box and WD-40 domain protein 22
Synonyms: Gm5164
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 382156
Homologene: 110776
Baiap2l2
Name: BAI1-associated protein 2-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 207495
Homologene: 11811
Olfr1350
Name: olfactory receptor 1350
Synonyms: MOR222-3, GA_x6K02T2QGBW-3300391-3301317
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258384
Olfr319
Name: olfactory receptor 319
Synonyms: MOR285-2, GA_x6K02T2NKPP-708319-707399
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258493
Olfr338
Name: olfactory receptor 338
Synonyms: MOR136-5, GA_x6K02T2NLDC-33070879-33071799
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258949
Homologene: 133647
Vmn1r198
Name: vomeronasal 1 receptor 198
Synonyms: V1ri3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 171254
Homologene: 110880
Foxb2
Name: forkhead box B2
Synonyms: Fkh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 14240
VEGA: 19
Homologene: 136311
Siae
Name: sialic acid acetylesterase
Synonyms: Ysg2, clone 165, LSE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22619
Homologene: 8001
Kmo
Name: kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98256
HGNC: HGNC:6381
Homologene: 2729
Itpripl2
Name: inositol 1,4,5-triphosphate receptor interacting protein-like 2
Synonyms: E030018N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 319622
Homologene: 45882
Bax
Name: BCL2-associated X protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12028
HGNC: HGNC:959
Homologene: 7242
Lce1i
Name: late cornified envelope 1I
Synonyms: 2310069N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 76585
Gm8298
Name: predicted gene 8298
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 666803
Homologene: 86204
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 90,788,216 bp
  • T to C, chromosome 1 at 106,023,672 bp
  • T to C, chromosome 1 at 175,647,194 bp
  • A to G, chromosome 2 at 34,715,253 bp
  • A to G, chromosome 2 at 36,377,117 bp
  • T to C, chromosome 2 at 41,408,342 bp
  • C to G, chromosome 2 at 85,044,325 bp
  • A to T, chromosome 3 at 39,010,274 bp
  • A to T, chromosome 3 at 59,877,219 bp
  • C to T, chromosome 3 at 92,777,681 bp
  • T to C, chromosome 3 at 108,856,408 bp
  • T to C, chromosome 4 at 131,937,406 bp
  • T to G, chromosome 4 at 144,893,564 bp
  • A to G, chromosome 5 at 5,675,912 bp
  • T to C, chromosome 5 at 108,802,240 bp
  • G to T, chromosome 7 at 4,368,900 bp
  • T to C, chromosome 7 at 6,570,825 bp
  • T to G, chromosome 7 at 13,450,915 bp
  • A to G, chromosome 7 at 28,156,569 bp
  • A to G, chromosome 7 at 45,461,891 bp
  • A to G, chromosome 7 at 65,699,124 bp
  • T to C, chromosome 7 at 86,734,120 bp
  • C to T, chromosome 7 at 118,489,869 bp
  • T to A, chromosome 7 at 140,249,123 bp
  • C to T, chromosome 8 at 85,640,544 bp
  • A to T, chromosome 8 at 108,955,991 bp
  • A to T, chromosome 8 at 111,465,831 bp
  • G to A, chromosome 9 at 37,616,923 bp
  • C to T, chromosome 9 at 67,334,320 bp
  • T to G, chromosome 9 at 109,403,088 bp
  • T to C, chromosome 9 at 109,606,998 bp
  • T to C, chromosome 10 at 118,159,683 bp
  • T to A, chromosome 11 at 23,457,975 bp
  • T to A, chromosome 11 at 58,702,051 bp
  • T to C, chromosome 11 at 80,111,556 bp
  • T to C, chromosome 11 at 97,148,729 bp
  • A to G, chromosome 11 at 116,063,654 bp
  • T to A, chromosome 13 at 11,555,448 bp
  • A to G, chromosome 13 at 22,354,998 bp
  • A to T, chromosome 13 at 31,917,721 bp
  • G to A, chromosome 13 at 64,903,758 bp
  • A to T, chromosome 13 at 96,666,663 bp
  • T to C, chromosome 15 at 79,271,583 bp
  • T to C, chromosome 15 at 81,643,217 bp
  • A to T, chromosome 16 at 59,000,206 bp
  • A to T, chromosome 16 at 97,590,871 bp
  • C to T, chromosome 17 at 65,803,861 bp
  • A to G, chromosome 18 at 35,770,478 bp
  • T to C, chromosome 18 at 78,209,067 bp
  • A to G, chromosome 18 at 86,713,148 bp
  • G to A, chromosome 19 at 8,783,930 bp
  • T to A, chromosome 19 at 16,872,767 bp
  • T to C, chromosome 19 at 45,777,006 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5571 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044395-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.