Strain Name:
C57BL/6J-MtgxR6365Btlr/Mmmh
Stock Number:
044515-MU
Citation ID:
RRID:MMRRC_044515-MU
Other Names:
R6365 (G1)
Major Collection:

Strain Information

Drd2
Name: dopamine receptor D2
Synonyms: D2 receptor, D2R, Drd-2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13489
VEGA: 9
HGNC: HGNC:3023
Homologene: 22561
Sema7a
Name: sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
Synonyms: Semaphorin K1, CDw108, Semal, 2900057C09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20361
VEGA: 9
Homologene: 2678
Kctd13
Name: potassium channel tetramerisation domain containing 13
Synonyms: 1500003N18Rik, Poldip1, Pdip1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233877
Homologene: 27800
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, Macf2, bullous pemphigoid antigen 1, athetoid, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Gdi2
Name: GDP dissociation inhibitor 2
Synonyms: GDI beta, GDI-B, GDIB, Gdi3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14569
VEGA: 13
HGNC: HGNC:4227
Homologene: 37488
Igf1r
Name: insulin-like growth factor I receptor
Synonyms: CD221, IGF-1R, line 186, hyft, A330103N21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16001
HGNC: HGNC:5465
Homologene: 30997
Atp2a2
Name: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Synonyms: sarco/endoplasmic reticulum Ca2+-ATPase 2, SERCA2, 9530097L16Rik, D5Wsu150e, SERCA2B, Serca2a
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11938
HGNC: HGNC:812
Homologene: 80167
Polk
Name: polymerase (DNA directed), kappa
Synonyms: Dinb1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 27015
VEGA: 13
HGNC: HGNC:9183
Homologene: 32140
Fcho2
Name: FCH domain only 2
Synonyms: 5832424M12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218503
VEGA: 13
Homologene: 9030
Zbtb17
Name: zinc finger and BTB domain containing 17
Synonyms: mZ13, Miz1, Zfp100
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22642
Homologene: 2575
Otud7b
Name: OTU domain containing 7B
Synonyms: 4930463P07Rik, 2900060B22Rik, Za20d1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229603
Homologene: 10624
Ap5m1
Name: adaptor-related protein complex 5, mu 1 subunit
Synonyms: 4932432K03Rik, Mudeng
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 74385
VEGA: 14
Homologene: 10081
Trf
Name: transferrin
Synonyms: Tfn, HP
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22041
Homologene: 68153
Calcr
Name: calcitonin receptor
Synonyms: Clr
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12311
HGNC: HGNC:1440
Homologene: 1320
Dzip3
Name: DAZ interacting protein 3, zinc finger
Synonyms: 6430549P11Rik, 2310047C04Rik, 2A-HUB
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224170
Homologene: 8771
Vip
Name: vasoactive intestinal polypeptide
Synonyms: PHI, peptide histidine isoleucine
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22353
VEGA: 10
Homologene: 2539
Adam30
Name: a disintegrin and metallopeptidase domain 30
Synonyms: 4933424D07Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71078
HGNC: HGNC:208
Homologene: 11038
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Nid2
Name: nidogen 2
Synonyms: entactin-2, entactin 2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 18074
VEGA: 14
Homologene: 40575
Exosc10
Name: exosome component 10
Synonyms: PM/Scl-100, PM-Scl, RRP6, p4, p3, p2, Pmscl2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 50912
HGNC: HGNC:9138
Homologene: 31105
Zbtb8os
Name: zinc finger and BTB domain containing 8 opposite strand
Synonyms: 2310028N13Rik, 2010001H09Rik, Arch
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67106
Homologene: 12083
2900026A02Rik
Name: RIKEN cDNA 2900026A02 gene
Synonyms: LOC231620, Gm449
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243219
Homologene: 129566
Hibch
Name: 3-hydroxyisobutyryl-Coenzyme A hydrolase
Synonyms: HIBYL-COA-H, 2610509I15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227095
HGNC: HGNC:4908
Homologene: 5607
Fbxw11
Name: F-box and WD-40 domain protein 11
Synonyms: HOS, BTRCP2, BTRC2, Fbxw1b, 2310065A07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103583
Homologene: 76444
Agap3
Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Synonyms: MRIP-1, Crag, Centg3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 213990
Homologene: 23742
Robo4
Name: roundabout guidance receptor 4
Synonyms: 1200012D01Rik, Magic roundabout
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74144
Homologene: 10397
Foxp2
Name: forkhead box P2
Synonyms: 2810043D05Rik, D0Kist7
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 114142
Homologene: 134404
Naxe
Name: NAD(P)HX epimerase
Synonyms: ESTM37, APOA1BP, AI-BP, Apoa1bp
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 246703
Homologene: 70948
Gm11639
Name: predicted gene 11639
Synonyms: Gm11639, Efcab15
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 105242472
Nlrp12
Name: NLR family, pyrin domain containing 12
Synonyms: Nalp12
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 378425
Homologene: 16972
Abca9
Name: ATP-binding cassette, sub-family A member 9
Synonyms: D630040K07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217262
HGNC: HGNC:39
Homologene: 33332
Myo1f
Name: myosin IF
Synonyms: C330006B10Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17916
HGNC: HGNC:7600
Homologene: 56276
Bace1
Name: beta-site APP cleaving enzyme 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 23821
HGNC: HGNC:933
Homologene: 8014
Vmn1r53
Name: vomeronasal 1 receptor 53
Synonyms: VN5, V1rb3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113853
Homologene: 113975
Dnaaf11
Name: dynein axonemal assembly factor 11
Synonyms: LRTP, Lrrc6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 54562
Homologene: 34534
Papolg
Name: poly(A) polymerase gamma
Synonyms: 9630006B20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216578
Homologene: 56959
Mylk
Name: myosin, light polypeptide kinase
Synonyms: telokin, Mlck, MLCK210, MLCK108, 9530072E15Rik, A930019C19Rik, nmMlck
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 107589
HGNC: HGNC:7590
Homologene: 14202
Grm8
Name: glutamate receptor, metabotropic 8
Synonyms: mGluR8, Gprc1h
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14823
HGNC: HGNC:4600
Homologene: 654
Vmn2r58
Name: vomeronasal 2, receptor 58
Synonyms: EG628422
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 628422
Zfp959
Name: zinc finger protein 959
Synonyms: BC011426
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224893
Homologene: 138295
Palm2
Name: paralemmin 2
Synonyms: 53-H12, pEN70
Type: Gene
Species: Mouse
Chromosome: 4
Cnga1
Name: cyclic nucleotide gated channel alpha 1
Synonyms: Cncg
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12788
HGNC: HGNC:2148
Homologene: 55432
Fam234a
Name: family with sequence similarity 234, member A
Synonyms: Itfg3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106581
Homologene: 12932
Scg2
Name: secretogranin II
Synonyms: SgII, Chgc
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20254
Homologene: 2591
Prss40
Name: serine protease 40
Synonyms: Tesp2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 21756
Homologene: 69043
Klhl33
Name: kelch-like 33
Synonyms: EG546611
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 546611
VEGA: 14
Homologene: 52385
Cd48
Name: CD48 antigen
Synonyms: BLAST-1, Sgp-60, Bcm-1, BCM1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12506
HGNC: HGNC:1683
Homologene: 1347
Acot6
Name: acyl-CoA thioesterase 6
Synonyms: 4632408A20Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217700
Homologene: 72506
Cyp2c29
Name: cytochrome P450, family 2, subfamily c, polypeptide 29
Synonyms: AHOH, AHOHase, P450-2C, Ahh-1, Ah-2, Cyp2c
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13095
Homologene: 117948
Pbx4
Name: pre B cell leukemia homeobox 4
Synonyms: 2410015M21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 80720
Homologene: 57027
Vmn1r202
Name: vomeronasal 1 receptor 202
Synonyms: V1ri7
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171258
Homologene: 110880
Ifi44l
Name: interferon-induced protein 44 like
Synonyms: NS1178, H-28, H28
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 15061
Homologene: 48468
Fech
Name: ferrochelatase
Synonyms: fch, Fcl
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 14151
VEGA: 18
HGNC: HGNC:3647
Homologene: 113
Pdcd4
Name: programmed cell death 4
Synonyms: MA-3, TIS, D19Ucla1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18569
VEGA: 19
HGNC: HGNC:8763
Homologene: 7879
Or51l4
Name: olfactory receptor family 51 subfamily L member 4
Synonyms: GA_x6K02T2PBJ9-6483085-6482126, MOR17-1, Olfr630
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259102
Homologene: 133674
Pde2a
Name: phosphodiesterase 2A, cGMP-stimulated
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 207728
HGNC: HGNC:8777
Homologene: 1952
Vmn1r159
Name: vomeronasal 1 receptor 159
Synonyms: Gm16507
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 670857
Homologene: 104166
Uox
Name: urate oxidase
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22262
Homologene: 7584
Sowahc
Name: sosondowah ankyrin repeat domain family member C
Synonyms: C820004L04Rik, Ankrd57
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 268301
Homologene: 49723
Ctsd
Name: cathepsin D
Synonyms: CatD, CD
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13033
HGNC: HGNC:2529
Homologene: 55616
H2bc6
Name: H2B clustered histone 6
Synonyms: Hist1h2be
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 319179
Homologene: 136358
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 34,191,927 bp
  • A to G, chromosome 1 at 34,552,517 bp
  • T to A, chromosome 1 at 52,868,937 bp
  • T to A, chromosome 1 at 79,435,300 bp
  • A to T, chromosome 1 at 171,682,164 bp
  • A to G, chromosome 3 at 88,057,991 bp
  • T to G, chromosome 3 at 96,155,250 bp
  • T to C, chromosome 3 at 98,161,034 bp
  • C to T, chromosome 3 at 146,624,577 bp
  • C to T, chromosome 3 at 151,761,505 bp
  • G to T, chromosome 4 at 57,709,675 bp
  • A to T, chromosome 4 at 129,343,152 bp
  • G to A, chromosome 4 at 141,463,383 bp
  • T to C, chromosome 4 at 148,561,105 bp
  • T to A, chromosome 5 at 24,474,985 bp
  • T to C, chromosome 5 at 72,604,945 bp
  • G to T, chromosome 5 at 113,182,644 bp
  • A to G, chromosome 5 at 122,461,916 bp
  • T to C, chromosome 6 at 3,711,455 bp
  • T to C, chromosome 6 at 15,286,685 bp
  • C to T, chromosome 6 at 27,363,227 bp
  • T to C, chromosome 6 at 90,224,259 bp
  • T to C, chromosome 7 at 3,239,888 bp
  • T to A, chromosome 7 at 22,843,401 bp
  • T to A, chromosome 7 at 41,864,183 bp
  • G to T, chromosome 7 at 68,190,050 bp
  • C to T, chromosome 7 at 101,510,363 bp
  • T to A, chromosome 7 at 103,755,195 bp
  • G to A, chromosome 7 at 126,930,690 bp
  • G to A, chromosome 7 at 142,385,577 bp
  • T to G, chromosome 8 at 69,872,207 bp
  • G to T, chromosome 9 at 37,410,712 bp
  • C to T, chromosome 9 at 45,854,676 bp
  • A to T, chromosome 9 at 49,406,949 bp
  • T to C, chromosome 9 at 57,954,905 bp
  • A to G, chromosome 9 at 103,222,128 bp
  • C to T, chromosome 10 at 5,644,021 bp
  • T to C, chromosome 10 at 59,223,527 bp
  • T to C, chromosome 11 at 23,882,290 bp
  • C to A, chromosome 11 at 32,720,623 bp
  • A to G, chromosome 11 at 104,924,586 bp
  • T to A, chromosome 11 at 110,145,655 bp
  • A to G, chromosome 12 at 84,109,412 bp
  • A to G, chromosome 13 at 3,565,093 bp
  • A to T, chromosome 13 at 22,502,204 bp
  • C to T, chromosome 13 at 23,585,658 bp
  • A to T, chromosome 13 at 96,484,009 bp
  • A to T, chromosome 13 at 98,789,859 bp
  • A to G, chromosome 14 at 19,803,133 bp
  • T to C, chromosome 14 at 49,078,828 bp
  • T to C, chromosome 14 at 50,891,837 bp
  • A to T, chromosome 15 at 66,454,134 bp
  • A to G, chromosome 16 at 34,860,591 bp
  • T to A, chromosome 16 at 48,931,273 bp
  • C to A, chromosome 17 at 26,220,455 bp
  • G to A, chromosome 17 at 30,748,568 bp
  • A to G, chromosome 17 at 33,586,116 bp
  • T to A, chromosome 17 at 55,897,785 bp
  • T to C, chromosome 18 at 64,458,180 bp
  • T to C, chromosome 19 at 39,307,754 bp
  • T to C, chromosome 19 at 53,922,133 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6365 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044515-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.