Strain Name:
C57BL/6J-MtgxR6698Btlr/Mmmh
Stock Number:
044816-MU
Citation ID:
RRID:MMRRC_044816-MU
Other Names:
R6698 (G1)
Major Collection:

Strain Information

Cdk17
Name: cyclin dependent kinase 17
Synonyms: 6430598J10Rik, Pctk2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237459
VEGA: 10
HGNC: HGNC:8750
Homologene: 55666
Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 77595
Homologene: 28122
Itga5
Name: integrin alpha 5 (fibronectin receptor alpha)
Synonyms: Cd49e, Fnra
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16402
VEGA: 15
HGNC: HGNC:6141
Homologene: 20508
Lrba
Name: LPS-responsive beige-like anchor
Synonyms: Lba, D3Ertd775e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80877
HGNC: HGNC:1742
Homologene: 36205
Rcc2
Name: regulator of chromosome condensation 2
Synonyms: 2610510H01Rik, Td60, 2610529N02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 108911
Homologene: 10282
Kif1b
Name: kinesin family member 1B
Synonyms: Kif1b beta, A530096N05Rik, N-3 kinesin, D4Mil1e, KIF1Bp204, KIF1Bp130, Kif1b alpha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16561
Homologene: 99835
Xpo1
Name: exportin 1
Synonyms: Crm1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103573
Homologene: 2554
Lmtk2
Name: lemur tyrosine kinase 2
Synonyms: KPI-2, KPI2, A330101P12Rik, 2900041G10Rik, BREK, AATYK2, cprk
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231876
Homologene: 8948
Mark4
Name: MAP/microtubule affinity regulating kinase 4
Synonyms: Markl1, 2410090P21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232944
Homologene: 57146
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 21819
Homologene: 2430
Nif3l1
Name: Ngg1 interacting factor 3-like 1 (S. pombe)
Synonyms: 1110030G24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 65102
Homologene: 5881
Flvcr1
Name: feline leukemia virus subgroup C cellular receptor 1
Synonyms: Mfsd7b, 9630055N22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226844
Homologene: 56661
Gask1b
Name: golgi associated kinase 1B
Synonyms: Ened, 2210419I08Rik, Fam198b, 1110032E23Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 68659
Homologene: 9590
Rpn2
Name: ribophorin II
Synonyms: Rpn-2, 1300012C06Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20014
Homologene: 2214
Brca2
Name: breast cancer 2, early onset
Synonyms: RAB163, Fancd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12190
HGNC: HGNC:1101
Homologene: 41
Pnkd
Name: paroxysmal nonkinesiogenic dyskinesia
Synonyms: Brp17, 2810403H05Rik, 2210013N15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 56695
HGNC: HGNC:9153
Homologene: 75045
Wnt5a
Name: wingless-type MMTV integration site family, member 5A
Synonyms: 8030457G12Rik, Wnt-5a
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 22418
Homologene: 20720
Mis12
Name: MIS12 kinetochore complex component
Synonyms: 2510025F08Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67139
Homologene: 11429
Col5a3
Name: collagen, type V, alpha 3
Synonyms: Pro-alpha3(V)
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 53867
Homologene: 9253
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Camk2g
Name: calcium/calmodulin-dependent protein kinase II gamma
Synonyms: Camkg, CaMK II, Ca2+/calmodulin-dependent protein kinase II, 5930429P18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12325
VEGA: 14
HGNC: HGNC:1463
Homologene: 15596
Gpr158
Name: G protein-coupled receptor 158
Synonyms: 5330427M13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241263
Homologene: 19381
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Gm7455, Col6a5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 665033
Homologene: 122792
Glp1r
Name: glucagon-like peptide 1 receptor
Synonyms: GLP1Rc, GLP-1R
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14652
VEGA: 17
HGNC: HGNC:4324
Homologene: 1558
Synj1
Name: synaptojanin 1
Synonyms: A930006D20Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 104015
Homologene: 48252
Klf11
Name: Kruppel-like transcription factor 11
Synonyms: Tieg2b, Tieg2, Tieg3, D12Ertd427e
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 194655
Homologene: 2668
Gabrp
Name: gamma-aminobutyric acid type A receptor subunit pi
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216643
HGNC: HGNC:4089
Homologene: 22798
Prkn
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: PRKN, Parkin, Park2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 50873
HGNC: HGNC:8607
Homologene: 3355
Nlrx1
Name: NLR family member X1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270151
VEGA: 9
Homologene: 11623
Skint4
Name: selection and upkeep of intraepithelial T cells 4
Synonyms: 9530098N22Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320640
Tcp11
Name: t-complex protein 11
Synonyms: D17Ken1, Tcp-11
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21463
Homologene: 8433
Gsdmc3
Name: gasdermin C3
Synonyms: 9930109F21Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 270328
HGNC: HGNC:7151
Homologene: 69487
Catsperb
Name: cation channel sperm associated auxiliary subunit beta
Synonyms: 4932415G16Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 271036
VEGA: 12
Homologene: 81904
Fancg
Name: Fanconi anemia, complementation group G
Synonyms: Xrcc9
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 60534
HGNC: HGNC:3588
Homologene: 3402
Gsdmc4
Name: gasdermin C4
Synonyms: 9030605I04Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 74548
HGNC: HGNC:7151
Homologene: 69487
Trib3
Name: tribbles pseudokinase 3
Synonyms: Ifld2, Trb3, Nipk, SKIP3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228775
Homologene: 10902
Rilpl2
Name: Rab interacting lysosomal protein-like 2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 80291
Homologene: 12723
Or5d20-ps1
Name: olfactory receptor family 5 subfamily D member 20, pseudogene 1
Synonyms: GA_x6K02T2Q125-49593880-49592930, Olfr1165-ps, MOR174-7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258642
Wdr49
Name: WD repeat domain 49
Synonyms: EG213248
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213248
Homologene: 18714
Or13m2-ps1
Name: olfactory receptor family 13 subfamily M member 2, pseudogene 1
Synonyms: Olfr451-ps1, GA_x6K02T2P3E9-4759141-4758206, MOR257-6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258017
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 58,450,489 bp
  • T to A, chromosome 1 at 74,350,677 bp
  • T to C, chromosome 1 at 191,025,732 bp
  • A to C, chromosome 2 at 21,827,110 bp
  • T to C, chromosome 2 at 41,302,946 bp
  • A to G, chromosome 2 at 88,101,217 bp
  • A to G, chromosome 2 at 152,338,419 bp
  • T to C, chromosome 2 at 157,297,410 bp
  • A to T, chromosome 3 at 75,429,366 bp
  • A to G, chromosome 3 at 79,936,595 bp
  • A to G, chromosome 3 at 86,304,425 bp
  • G to A, chromosome 3 at 90,182,508 bp
  • A to G, chromosome 4 at 43,007,034 bp
  • G to T, chromosome 4 at 112,119,899 bp
  • G to A, chromosome 4 at 140,702,275 bp
  • A to T, chromosome 4 at 149,274,956 bp
  • C to T, chromosome 5 at 124,469,780 bp
  • T to C, chromosome 5 at 144,174,919 bp
  • T to C, chromosome 5 at 150,532,394 bp
  • A to T, chromosome 6 at 42,801,202 bp
  • T to C, chromosome 7 at 19,429,437 bp
  • C to T, chromosome 9 at 20,779,033 bp
  • A to G, chromosome 9 at 44,265,807 bp
  • T to A, chromosome 9 at 105,934,175 bp
  • T to C, chromosome 10 at 93,228,678 bp
  • A to G, chromosome 11 at 23,294,040 bp
  • A to G, chromosome 11 at 33,557,017 bp
  • T to C, chromosome 11 at 71,025,186 bp
  • T to G, chromosome 12 at 24,653,619 bp
  • T to A, chromosome 12 at 101,509,207 bp
  • T to A, chromosome 14 at 20,742,708 bp
  • A to G, chromosome 14 at 28,518,463 bp
  • A to G, chromosome 15 at 63,860,271 bp
  • T to A, chromosome 15 at 63,893,764 bp
  • A to G, chromosome 15 at 66,839,362 bp
  • T to C, chromosome 15 at 103,351,381 bp
  • C to G, chromosome 16 at 90,960,452 bp
  • A to G, chromosome 17 at 11,067,296 bp
  • A to T, chromosome 17 at 28,071,830 bp
  • A to G, chromosome 17 at 30,936,401 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6698 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044816-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.