Strain Name:
C57BL/6J-MtgxR6802Btlr/Mmmh
Stock Number:
044915-MU
Citation ID:
RRID:MMRRC_044915-MU
Other Names:
R6802 (G1)
Major Collection:

Strain Information

Nrg1
Name: neuregulin 1
Synonyms: GGF, NDF, GGFII, HRG, 6030402G23Rik, SMDF, ARIA, HRGalpha, heregulin, HGL, Hgl, D230005F13Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 211323
HGNC: HGNC:7997
Homologene: 138451
Gli2
Name: GLI-Kruppel family member GLI2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14633
HGNC: HGNC:4318
Homologene: 12725
Arfgef1
Name: ADP ribosylation factor guanine nucleotide exchange factor 1
Synonyms: P200, ARFGEP1, D130059B05Rik, BIG1, D730028O18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 211673
Homologene: 4687
Ctdp1
Name: CTD phosphatase subunit 1
Synonyms: 4930563P03Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67655
HGNC: HGNC:2498
Homologene: 31254
Focad
Name: focadhesin
Synonyms: BC057079
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230393
Homologene: 9842
Mc4r
Name: melanocortin 4 receptor
Synonyms: Pkcp, Fatboy
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17202
VEGA: 18
HGNC: HGNC:6932
Homologene: 4320
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Robo1
Name: roundabout guidance receptor 1
Synonyms: DUTT1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19876
Homologene: 2206
1110004F10Rik
Name: RIKEN cDNA 1110004F10 gene
Synonyms: sid2057
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56372
Homologene: 8606
Pacs1
Name: phosphofurin acidic cluster sorting protein 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107975
VEGA: 19
Homologene: 9970
Mrpl15
Name: mitochondrial ribosomal protein L15
Synonyms: MRP-L7, Rpml7, HSPC145
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 27395
Homologene: 32210
Tph2
Name: tryptophan hydroxylase 2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216343
Homologene: 27831
Pms1
Name: PMS1 homolog 1, mismatch repair system component
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227099
HGNC: HGNC:9121
Homologene: 449
Agap3
Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Synonyms: MRIP-1, Centg3, Crag
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 213990
Homologene: 23742
Pla2g15
Name: phospholipase A2, group XV
Synonyms: Lpla2, Lypla3, LLPL, C87498
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 192654
Homologene: 8200
Ttll5
Name: tubulin tyrosine ligase-like family, member 5
Synonyms: STAMP, 4930556H18Rik, 2310009M18Rik, D630041K24Rik, 1700048H13Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320244
Homologene: 9013
Grm6
Name: glutamate receptor, metabotropic 6
Synonyms: mGluR6, nob3, nerg1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 108072
HGNC: HGNC:4598
Homologene: 20232
Sgtb
Name: small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
Synonyms: C630001O05Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218544
Homologene: 10409
Dhx57
Name: DExH-box helicase 57
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106794
VEGA: 17
Homologene: 56267
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, Dnhd3, Dnahc2, 2900022L05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC382129, LOC234973, 9430076A06Rik, D430038H04Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
F5
Name: coagulation factor V
Synonyms: Cf-5, Cf5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Fbxo30
Name: F-box protein 30
Synonyms: 1700026A16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71865
Homologene: 12959
Lrguk
Name: leucine-rich repeats and guanylate kinase domain containing
Synonyms: 4921528H16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74354
Homologene: 34923
Gml2
Name: glycosylphosphatidylinositol anchored molecule like 2
Synonyms: hematopoietic cell-specific transcript, 1700057K19Rik, Hemt1, HemT
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 15202
HGNC: HGNC:4375
Homologene: 48071
Rabgap1l
Name: RAB GTPase activating protein 1-like
Synonyms: 9630005B12Rik, Hh1, 8430421H08Rik, 5830411O09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 29809
Homologene: 8143
Zfp352
Name: zinc finger protein 352
Synonyms: 2czf48
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 236537
Homologene: 45160
Or4c100
Name: olfactory receptor family 4 subfamily C member 100
Synonyms: Olfr1186, GA_x6K02T2Q125-50012960-50013871, MOR230-5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258523
Homologene: 110555
Slc39a12
Name: solute carrier family 39 (zinc transporter), member 12
Synonyms: LOC277468
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 277468
Homologene: 17654
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Kcnj6
Name: potassium inwardly-rectifying channel, subfamily J, member 6
Synonyms: KCNJ7, GIRK2, Kir3.2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 16522
VEGA: 16
HGNC: HGNC:6267
Homologene: 1688
Ctsj
Name: cathepsin J
Synonyms: rat gene/Cathepsin L-related protein, CATP, CatRLP, Ctsp, Cat P
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 26898
VEGA: 13
Homologene: 137246
Hsf4
Name: heat shock transcription factor 4
Synonyms: ldis1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 26386
HGNC: HGNC:5227
Homologene: 100128
Vmn2r90
Name: vomeronasal 2, receptor 90
Synonyms: EG626942
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 626942
Neil2
Name: nei like 2 (E. coli)
Synonyms: NEH2, LOC382913
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 382913
VEGA: 14
Homologene: 17032
Tgm1
Name: transglutaminase 1, K polypeptide
Synonyms: K polypeptide, TGase 1, TGase1, TG K, 2310004J08Rik, protein-glutamine-gamma-glutamyltransferase
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21816
VEGA: 14
Homologene: 306
Sprr2k
Name: small proline-rich protein 2K
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20765
Coa8
Name: cytochrome c oxidase assembly factor 8
Synonyms: 1700081D05Rik, Apopt1, Apop-1, 2810002N01Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68020
Homologene: 12225
Glb1l3
Name: galactosidase, beta 1 like 3
Synonyms: 4921509F24Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70893
Homologene: 72240
Or8k22
Name: olfactory receptor family 8 subfamily K member 22
Synonyms: Olfr1054, MOR188-2, GA_x6K02T2Q125-47811880-47810942
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259021
Homologene: 133882
Apold1
Name: apolipoprotein L domain containing 1
Synonyms: LOC381823
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 381823
Homologene: 12781
Gtf2h2
Name: general transcription factor II H, polypeptide 2
Synonyms: 44kDa, p44, basal transcription factor 2, p44 subunit, Btf2p44
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 23894
Homologene: 1159
Socs1
Name: suppressor of cytokine signaling 1
Synonyms: SSI-1, JAK2-binding protein, STAT-induced STAT inhibitor 1, JAK-binding protein, JAB, Cish1, SOCS-1, Cish7
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12703
VEGA: 16
Homologene: 2776
Ccdc177
Name: coiled-coil domain containing 177
Synonyms: Gm1568, LOC380768
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 380768
VEGA: 12
Homologene: 128326
Zdhhc19
Name: zinc finger, DHHC domain containing 19
Synonyms: LOC245308
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 245308
Homologene: 34922
Prkra
Name: protein kinase, interferon inducible double stranded RNA dependent activator
Synonyms: Pact, lear, PRK, RAX
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 23992
HGNC: HGNC:9438
Homologene: 2738
Gm6401
Name: predicted gene 6401
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 115486427
Qsox1
Name: quiescin Q6 sulfhydryl oxidase 1
Synonyms: b2b2673Clo, QSOX, 1300003H02Rik, Qscn6
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 104009
HGNC: HGNC:9756
Homologene: 37690
Irgq
Name: immunity-related GTPase family, Q
Synonyms: FKSG27
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210146
Homologene: 17696
Or12k7
Name: olfactory receptor family 12 subfamily K member 7
Synonyms: Olfr360, GA_x6K02T2NLDC-33760081-33761034, MOR159-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258615
Homologene: 73997
Trav16
Name: T cell receptor alpha variable 16
Synonyms: Gm13896
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 195297
Iglc1
Name: immunoglobulin lambda constant 1
Synonyms: Clambda1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 110785
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 4,776,730 bp
  • A to T, chromosome 1 at 10,189,452 bp
  • A to T, chromosome 1 at 53,206,792 bp
  • G to A, chromosome 1 at 118,842,065 bp
  • A to C, chromosome 1 at 155,795,393 bp
  • A to T, chromosome 1 at 160,733,680 bp
  • A to T, chromosome 1 at 164,179,356 bp
  • C to T, chromosome 2 at 14,420,085 bp
  • A to G, chromosome 2 at 37,068,415 bp
  • A to T, chromosome 2 at 76,633,537 bp
  • G to T, chromosome 2 at 86,333,185 bp
  • A to G, chromosome 2 at 88,525,597 bp
  • A to G, chromosome 3 at 92,433,364 bp
  • T to C, chromosome 4 at 88,274,203 bp
  • G to A, chromosome 4 at 88,344,684 bp
  • A to T, chromosome 4 at 90,225,200 bp
  • T to A, chromosome 5 at 24,487,793 bp
  • A to G, chromosome 6 at 34,062,457 bp
  • G to A, chromosome 6 at 134,983,730 bp
  • A to G, chromosome 7 at 24,531,651 bp
  • A to T, chromosome 7 at 116,099,490 bp
  • T to C, chromosome 8 at 31,821,264 bp
  • G to A, chromosome 8 at 105,274,668 bp
  • T to C, chromosome 8 at 106,150,581 bp
  • C to T, chromosome 9 at 15,915,061 bp
  • T to C, chromosome 9 at 26,859,352 bp
  • C to T, chromosome 9 at 108,110,624 bp
  • G to T, chromosome 10 at 11,291,480 bp
  • A to T, chromosome 10 at 115,184,873 bp
  • A to T, chromosome 11 at 50,853,389 bp
  • A to T, chromosome 11 at 69,423,690 bp
  • A to T, chromosome 12 at 80,759,283 bp
  • A to G, chromosome 12 at 85,879,386 bp
  • G to T, chromosome 12 at 111,751,191 bp
  • G to A, chromosome 13 at 11,686,966 bp
  • A to T, chromosome 13 at 61,003,074 bp
  • T to C, chromosome 13 at 100,480,543 bp
  • A to T, chromosome 13 at 104,132,050 bp
  • T to A, chromosome 14 at 41,966,917 bp
  • T to A, chromosome 14 at 53,743,484 bp
  • C to T, chromosome 14 at 55,712,482 bp
  • A to G, chromosome 14 at 63,191,814 bp
  • T to A, chromosome 15 at 74,824,246 bp
  • C to A, chromosome 16 at 10,784,358 bp
  • T to C, chromosome 16 at 19,061,910 bp
  • T to C, chromosome 16 at 32,506,358 bp
  • T to G, chromosome 16 at 72,933,313 bp
  • T to C, chromosome 16 at 94,762,577 bp
  • T to A, chromosome 17 at 17,712,089 bp
  • A to G, chromosome 17 at 80,275,321 bp
  • C to A, chromosome 18 at 66,859,417 bp
  • A to T, chromosome 18 at 80,420,441 bp
  • T to C, chromosome 19 at 5,152,784 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6802 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044915-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.