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Strain Name:
C57BL/6J-MtgxR6829Btlr/Mmmh
Stock Number:
044939-MU
Citation ID:
RRID:MMRRC_044939-MU
Other Names:
R6829 (G1)
Major Collection:

Strain Information

Sema7a
Name: sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
Synonyms: Semaphorin K1, CDw108, Semal, 2900057C09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20361
VEGA: 9
Homologene: 2678
Adcy9
Name: adenylate cyclase 9
Synonyms: D16Wsu65e, ACtp10
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 11515
HGNC: HGNC:240
Homologene: 868
Gon4l
Name: gon-4 like
Synonyms: 1500041I23Rik, 2610100B20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76022
Homologene: 13002
Il17rd
Name: interleukin 17 receptor D
Synonyms: Sef, Sef-S, 2810004A10Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 171463
VEGA: 14
Homologene: 9717
Dcaf1
Name: DDB1 and CUL4 associated factor 1
Synonyms: B930007L02Rik, Vprbp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 321006
Homologene: 8805
Washc4
Name: WASH complex subunit 4
Synonyms: A230046K03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 319277
VEGA: 10
Homologene: 123926
Zfhx3
Name: zinc finger homeobox 3
Synonyms: WBP9, A230102L03Rik, Atbf1, Sci
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Dmxl1
Name: Dmx-like 1
Synonyms: C630007L23Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240283
HGNC: HGNC:2937
Homologene: 21136
Rsf1
Name: remodeling and spacing factor 1
Synonyms: p325, XAP8, Hbxap, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Tasor
Name: transcription activation suppressor
Synonyms: 4933409E02Rik, D14Abb1e, MommeD6, Fam208a
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218850
VEGA: 14
Homologene: 9062
Polg
Name: polymerase (DNA directed), gamma
Synonyms: Pol gamma, polymerase gamma, mitochondrial DNA polymerase gamma, mitochondrial DNA polymerase-gamma, Polga
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18975
HGNC: HGNC:9179
Homologene: 2016
Igsf9
Name: immunoglobulin superfamily, member 9
Synonyms: NRT1, Dasm1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 93842
Homologene: 10815
Fbxw4
Name: F-box and WD-40 domain protein 4
Synonyms: dactylin, Fbw4, dactylyn
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 30838
Homologene: 32197
Elac2
Name: elaC ribonuclease Z 2
Synonyms: 1110017O07Rik, D11Wsu80e, tRNase Z(L)
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68626
Homologene: 6403
Slc4a8
Name: solute carrier family 4 (anion exchanger), member 8
Synonyms: sodium bicarbonate cotransporter isoform 3 kNBC-3, KNBC-3, NDCBE
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 59033
Homologene: 68419
Or4f62
Name: olfactory receptor family 4 subfamily F member 62
Synonyms: GA_x6K02T2Q125-73202172-73203134, MOR245-16, Olfr1318
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258022
Homologene: 134079
Khdrbs3
Name: KH domain containing, RNA binding, signal transduction associated 3
Synonyms: SLM-2, T-STAR, Etle, Salp
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 13992
VEGA: 15
Homologene: 4780
Rb1cc1
Name: RB1-inducible coiled-coil 1
Synonyms: LaXp180, 2900055E04Rik, Cc1, 5930404L04Rik, Fip200
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12421
Homologene: 7659
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22635
Homologene: 124417
Trpm5
Name: transient receptor potential cation channel, subfamily M, member 5
Synonyms: Mtr1, Ltrpc5, 9430099A16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56843
Homologene: 22818
Or8k33
Name: olfactory receptor family 8 subfamily K member 33
Synonyms: GA_x6K02T2Q125-48039418-48038477, MOR192-1, Olfr1080
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258404
Homologene: 104285
Slc2a2
Name: solute carrier family 2 (facilitated glucose transporter), member 2
Synonyms: liver-type glucose transporter, Glut-2, Glut2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20526
Homologene: 68047
Adam2
Name: a disintegrin and metallopeptidase domain 2
Synonyms: Ph30-beta, Ftnb, fertilin beta
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 11495
VEGA: 14
HGNC: HGNC:198
Homologene: 1127
Pnliprp2
Name: pancreatic lipase-related protein 2
Synonyms: PLRP2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18947
VEGA: 19
HGNC: HGNC:9157
Homologene: 3936
Plch1
Name: phospholipase C, eta 1
Synonyms: PLCeta1, Plcl3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 269437
Homologene: 88833
Adamts5
Name: ADAM metallopeptidase with thrombospondin type 1 motif 5
Synonyms: ADAM-TS5, 9530092O11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 23794
VEGA: 16
HGNC: HGNC:221
Homologene: 5109
Gm2a
Name: GM2 ganglioside activator protein
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14667
HGNC: HGNC:4367
Homologene: 349
Jph1
Name: junctophilin 1
Synonyms: mitsugumin72, JP-1, ENSMUSG00000054314
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 57339
Homologene: 10761
Pgc
Name: progastricsin (pepsinogen C)
Synonyms: Upg-1, Upg1, 2210410L06Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 109820
HGNC: HGNC:8890
Homologene: 55669
Vmn1r14
Name: vomeronasal 1 receptor 14
Synonyms: V1rc7
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113864
Homologene: 74373
Or5ac16
Name: olfactory receptor family 5 subfamily AC member 16
Synonyms: GA_x54KRFPKG5P-55416332-55415412, MOR182-8, Olfr198
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258036
Homologene: 51800
Wfdc3
Name: WAP four-disulfide core domain 3
Synonyms: 1700015L13Rik, 1700127F16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71856
Homologene: 122221
Gsg1l2
Name: GSG1-like 2
Synonyms: Gm12302
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 544792
Homologene: 132038
Ccdc198
Name: coiled-coil domain containing 198
Synonyms: 1700011H14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67082
Homologene: 49528
Or2w1
Name: olfactory receptor family 2 subfamily W member 1
Synonyms: IA3, GA_x6K02T2N5E5-9379-8514, MOR256-31, GA_x6K02T2QHY8-12114828-12113875, MOR256-37P, MOR256-61, Olfr42, Olfr263-ps1, Olfr263
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 18341
HGNC: HGNC:8281
Homologene: 12791
Sdf2l1
Name: stromal cell-derived factor 2-like 1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 64136
Homologene: 11101
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 6,249,264 bp
  • C to A, chromosome 1 at 17,004,423 bp
  • A to G, chromosome 1 at 172,495,674 bp
  • A to T, chromosome 2 at 86,553,269 bp
  • G to C, chromosome 2 at 112,155,794 bp
  • C to T, chromosome 2 at 164,734,258 bp
  • C to T, chromosome 3 at 28,727,441 bp
  • T to G, chromosome 3 at 63,697,518 bp
  • T to A, chromosome 3 at 88,880,106 bp
  • T to G, chromosome 5 at 110,046,926 bp
  • A to G, chromosome 5 at 137,416,278 bp
  • T to C, chromosome 6 at 57,233,551 bp
  • A to G, chromosome 7 at 79,460,109 bp
  • CG to CGACGGCGGGG, chromosome 7 at 97,579,908 bp
  • A to G, chromosome 7 at 143,069,429 bp
  • T to A, chromosome 8 at 15,122,643 bp
  • C to T, chromosome 8 at 108,950,283 bp
  • A to G, chromosome 9 at 57,960,898 bp
  • T to A, chromosome 9 at 106,838,604 bp
  • T to C, chromosome 10 at 83,560,516 bp
  • T to C, chromosome 11 at 55,103,750 bp
  • A to G, chromosome 11 at 64,989,364 bp
  • T to C, chromosome 11 at 67,774,858 bp
  • T to A, chromosome 13 at 21,132,853 bp
  • T to C, chromosome 13 at 74,728,344 bp
  • A to G, chromosome 13 at 114,819,444 bp
  • C to T, chromosome 14 at 27,087,422 bp
  • A to G, chromosome 14 at 27,442,481 bp
  • A to G, chromosome 14 at 49,226,568 bp
  • A to T, chromosome 14 at 66,027,997 bp
  • T to C, chromosome 15 at 69,092,961 bp
  • A to G, chromosome 15 at 100,800,538 bp
  • A to G, chromosome 16 at 4,307,154 bp
  • C to G, chromosome 16 at 17,132,294 bp
  • A to G, chromosome 16 at 59,201,535 bp
  • A to T, chromosome 16 at 85,870,071 bp
  • A to T, chromosome 17 at 47,732,781 bp
  • C to T, chromosome 18 at 49,921,024 bp
  • A to G, chromosome 19 at 45,636,374 bp
  • G to A, chromosome 19 at 58,759,873 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6829 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044939-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.