Strain Name:
C57BL/6J-MtgxR6855Btlr/Mmmh
Stock Number:
045024-MU
Citation ID:
RRID:MMRRC_045024-MU
Other Names:
R6855 (G1)
Major Collection:

Strain Information

Ppp5c
Name: protein phosphatase 5, catalytic subunit
Synonyms: PP5, ANP receptor
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19060
HGNC: HGNC:9322
Homologene: 4550
Dnm2
Name: dynamin 2
Synonyms: Dyn2, b2b2159Clo
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13430
HGNC: HGNC:2974
Homologene: 90883
Elp2
Name: elongator acetyltransferase complex subunit 2
Synonyms: Statip1, Stat3-interacting protein, StIP1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 58523
VEGA: 18
Homologene: 6019
Ghitm
Name: growth hormone inducible transmembrane protein
Synonyms: 1010001P14Rik, Tmbim5, PTD010, C77840
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66092
VEGA: 14
Homologene: 8667
Trnt1
Name: tRNA nucleotidyl transferase, CCA-adding, 1
Synonyms: 2410043H24Rik, CGI-47, 2610044E04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 70047
Homologene: 9333
Rnf38
Name: ring finger protein 38
Synonyms: 2610202O07Rik, 1700065B19Rik, Oip1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 73469
Homologene: 32550
Lrrc2
Name: leucine rich repeat containing 2
Synonyms: 4933431K03Rik, 2400002D05Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74249
Homologene: 23454
Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 77595
Homologene: 28122
Fryl
Name: FRY like transcription coactivator
Synonyms: 9030227G01Rik, 2310004H21Rik, 2510002A14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72313
Homologene: 103956
Nek7
Name: NIMA (never in mitosis gene a)-related expressed kinase 7
Synonyms: 2810460C19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 59125
Homologene: 69340
Phf3
Name: PHD finger protein 3
Synonyms: 2310061N19Rik, AU020177
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 213109
HGNC: HGNC:8921
Homologene: 9040
Dennd4c
Name: DENN domain containing 4C
Synonyms: 1700065A05Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329877
Homologene: 23057
Itprid2
Name: ITPR interacting domain containing 2
Synonyms: Ssfa2, CS1, CS-1, SPAG13, KRAP
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70599
Homologene: 4912
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: A530081C03Rik, Murr2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17847
Homologene: 40978
Gbf1
Name: golgi-specific brefeldin A-resistance factor 1
Synonyms: 1700083E03Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107338
HGNC: HGNC:4181
Homologene: 37897
Pvr
Name: poliovirus receptor
Synonyms: CD155, Tage4, D7Ertd458e, necl-5, 3830421F03Rik, mE4, Taa1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 52118
HGNC: HGNC:9705
Homologene: 79541
Rims2
Name: regulating synaptic membrane exocytosis 2
Synonyms: RIM2, 2810036I15Rik, Syt3-rs
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 116838
VEGA: 15
Homologene: 81639
Rrp1b
Name: ribosomal RNA processing 1B
Synonyms: 2600005C20Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 72462
Homologene: 57086
Peg3
Name: paternally expressed 3
Synonyms: Zfp102, End4, Gcap4, Pw1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18616
HGNC: HGNC:8826
Homologene: 31363
Zfp868
Name: zinc finger protein 868
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234362
Homologene: 74376
Rasa3
Name: RAS p21 protein activator 3
Synonyms: R-Ras gap, scat, GAPIII activator 3, GAPIII, Ras GTPase-activating protein III, hlb381
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 19414
Homologene: 7217
Dkk2
Name: dickkopf WNT signaling pathway inhibitor 2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56811
HGNC: HGNC:2892
Homologene: 8681
Mpp3
Name: membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
Synonyms: Dlgh3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13384
HGNC: HGNC:7221
Homologene: 31065
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Tsc22d2
Name: TSC22 domain family, member 2
Synonyms: 1810043J12Rik, 5530402M19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72033
Homologene: 8860
Ssh1
Name: slingshot protein phosphatase 1
Synonyms: mSSH-1L, LOC384311
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231637
Homologene: 41299
Gm14325
Name: predicted gene 14325
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329575
Homologene: 134324
Cdh23
Name: cadherin related 23 (otocadherin)
Synonyms: mdfw, ahl, nmf112, nmf252, 4930542A03Rik, nmf181, sals, USH1D, bob
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22295
Homologene: 11142
Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Synonyms: 9430028L06Rik, Piezo2, Fam38b, Fam38b2, 9030411M15Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 667742
Homologene: 49695
Cdh8
Name: cadherin 8
Synonyms: cad8
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12564
HGNC: HGNC:1767
Homologene: 55604
Uspl1
Name: ubiquitin specific peptidase like 1
Synonyms: E430026A01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231915
Homologene: 4235
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Efcab7
Name: EF-hand calcium binding domain 7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230500
Homologene: 19952
Vmn1r58
Name: vomeronasal 1 receptor 58
Synonyms: V3R4, V1rd4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 81014
Homologene: 41799
Kcnma1
Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Synonyms: mSlo1, Slo, 5730414M22Rik, BK channel alpha subunit, BKCa, MaxiK, Slo1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16531
HGNC: HGNC:6284
Homologene: 1693
Nup210
Name: nucleoporin 210
Synonyms: gp190, Pom210, gp210
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54563
Homologene: 41286
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: 3110047P20Rik, B830017A01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 319807
Homologene: 14974
Col15a1
Name: collagen, type XV, alpha 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12819
HGNC: HGNC:2192
Homologene: 1396
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: C230094A16Rik, 2900083P10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237711
Homologene: 104282
Nfil3
Name: nuclear factor, interleukin 3, regulated
Synonyms: E4BP4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 18030
HGNC: HGNC:7787
Homologene: 3928
Cyp3a57
Name: cytochrome P450, family 3, subfamily a, polypeptide 57
Synonyms: EG622127
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 622127
Homologene: 135775
Vmn2r62
Name: vomeronasal 2, receptor 62
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 546964
Homologene: 104832
Aass
Name: aminoadipate-semialdehyde synthase
Synonyms: LOR/SDH, Lorsdh
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 30956
Homologene: 4212
Fam186a
Name: family with sequence similarity 186, member A
Synonyms: 1700030F18Rik, LOC380973
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72277
Sidt1
Name: SID1 transmembrane family, member 1
Synonyms: B830021E24Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 320007
Homologene: 41189
Sgip1
Name: SH3-domain GRB2-like (endophilin) interacting protein 1
Synonyms: 3110007P09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 73094
Homologene: 13001
Pygm
Name: muscle glycogen phosphorylase
Synonyms: PG
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19309
HGNC: HGNC:9726
Homologene: 2145
Tpi1
Name: triosephosphate isomerase 1
Synonyms: Tpi-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21991
Homologene: 128432
Poglut2
Name: protein O-glucosyltransferase 2
Synonyms: 1810049A15Rik, Kdelc1, EP58, Kdel1, 5730416C13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72050
Homologene: 11367
Fhl3
Name: four and a half LIM domains 3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14201
HGNC: HGNC:3704
Homologene: 37928
Shisal2b
Name: shisa like 2B
Synonyms: Fam159b, A930021C24Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 77803
VEGA: 13
Homologene: 19019
Pigz
Name: phosphatidylinositol glycan anchor biosynthesis, class Z
Synonyms: F630022B06Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239827
Homologene: 130742
Erich3
Name: glutamate rich 3
Synonyms: 5031409G23Rik, 4922501L14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 209601
Homologene: 27877
Rptn
Name: repetin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20129
Homologene: 84780
Thumpd2
Name: THUMP domain containing 2
Synonyms: 2810025A12Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 72167
VEGA: 17
Homologene: 11898
Grxcr1
Name: glutaredoxin, cysteine rich 1
Synonyms: pi, tde
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 433899
Homologene: 42423
Nit1
Name: nitrilase 1
Synonyms: ESTM30
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 27045
HGNC: HGNC:7828
Homologene: 4091
Dchs2
Name: dachsous cadherin related 2
Synonyms: LOC229459
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 100534287
Or8k31-ps1
Name: olfactory receptor family 8 subfamily K member 31, pseudogene 1
Synonyms: GA_x6K02T2Q125-48011447-48010506, Olfr1077-ps1, MOR189-4P
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 625853
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 30,820,123 bp
  • C to A, chromosome 1 at 44,110,827 bp
  • C to T, chromosome 1 at 138,515,682 bp
  • A to C, chromosome 1 at 171,343,562 bp
  • G to C, chromosome 2 at 40,628,696 bp
  • C to T, chromosome 2 at 79,657,705 bp
  • T to C, chromosome 2 at 86,526,169 bp
  • T to A, chromosome 2 at 177,832,842 bp
  • G to A, chromosome 3 at 58,416,814 bp
  • G to A, chromosome 3 at 83,348,194 bp
  • A to G, chromosome 3 at 90,136,924 bp
  • G to A, chromosome 3 at 93,398,251 bp
  • T to G, chromosome 3 at 132,177,922 bp
  • G to T, chromosome 3 at 154,762,649 bp
  • C to T, chromosome 4 at 44,149,224 bp
  • G to T, chromosome 4 at 47,245,544 bp
  • A to C, chromosome 4 at 86,836,457 bp
  • T to G, chromosome 4 at 99,900,580 bp
  • T to C, chromosome 4 at 102,962,376 bp
  • G to A, chromosome 4 at 124,707,522 bp
  • G to T, chromosome 5 at 63,804,451 bp
  • C to A, chromosome 5 at 68,032,094 bp
  • A to T, chromosome 5 at 73,059,500 bp
  • G to T, chromosome 5 at 113,942,575 bp
  • T to A, chromosome 5 at 145,372,566 bp
  • C to A, chromosome 5 at 149,187,845 bp
  • G to A, chromosome 6 at 23,114,845 bp
  • T to C, chromosome 6 at 91,040,853 bp
  • T to A, chromosome 6 at 106,777,922 bp
  • T to C, chromosome 6 at 124,812,463 bp
  • A to C, chromosome 7 at 5,410,452 bp
  • A to C, chromosome 7 at 6,708,798 bp
  • T to G, chromosome 7 at 17,006,966 bp
  • C to T, chromosome 7 at 19,909,214 bp
  • T to A, chromosome 7 at 42,788,988 bp
  • A to T, chromosome 8 at 13,585,029 bp
  • A to C, chromosome 8 at 69,611,579 bp
  • G to C, chromosome 8 at 99,190,217 bp
  • C to T, chromosome 9 at 21,476,585 bp
  • T to A, chromosome 9 at 110,953,182 bp
  • A to T, chromosome 10 at 60,306,122 bp
  • T to C, chromosome 11 at 23,452,569 bp
  • T to C, chromosome 11 at 29,751,381 bp
  • A to G, chromosome 11 at 102,013,325 bp
  • T to A, chromosome 13 at 52,968,605 bp
  • T to C, chromosome 13 at 104,863,706 bp
  • A to G, chromosome 14 at 23,367,611 bp
  • C to A, chromosome 14 at 37,125,902 bp
  • T to G, chromosome 15 at 39,345,515 bp
  • T to A, chromosome 15 at 76,186,618 bp
  • T to A, chromosome 15 at 99,954,875 bp
  • A to G, chromosome 16 at 31,945,218 bp
  • A to C, chromosome 16 at 44,245,343 bp
  • A to G, chromosome 17 at 32,052,745 bp
  • A to G, chromosome 17 at 67,782,155 bp
  • C to A, chromosome 17 at 81,044,170 bp
  • T to A, chromosome 18 at 24,606,877 bp
  • C to T, chromosome 18 at 63,090,879 bp
  • G to T, chromosome 19 at 6,393,757 bp
  • T to C, chromosome 19 at 46,279,941 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6855 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045024-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.