Strain Name:
C57BL/6J-MtgxR6902Btlr/Mmmh
Stock Number:
045032-MU
Citation ID:
RRID:MMRRC_045032-MU
Other Names:
R6902 (G1)
Major Collection:

Strain Information

Pcf11
Name: PCF11 cleavage and polyadenylation factor subunit
Synonyms: 2500001H09Rik, 5730417B17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74737
Homologene: 32282
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: Megalin, D230004K18Rik, Gp330, b2b1625.2Clo
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Adgrl3
Name: adhesion G protein-coupled receptor L3
Synonyms: LEC3, Lphn3, D130075K09Rik, lectomedin 3, 5430402I23Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 319387
Homologene: 22878
Igf1r
Name: insulin-like growth factor I receptor
Synonyms: IGF-1R, CD221, hyft, A330103N21Rik, line 186
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16001
HGNC: HGNC:5465
Homologene: 30997
Vipr2
Name: vasoactive intestinal peptide receptor 2
Synonyms: VIP receptor subtype 2, VPAC2, VPAC2R, Vip2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 22355
Homologene: 2540
Carmil1
Name: capping protein regulator and myosin 1 linker 1
Synonyms: Carmil, Lrrc16, Lrrc16a, 1110037D04Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 68732
Homologene: 9757
Pan2
Name: PAN2 poly(A) specific ribonuclease subunit
Synonyms: Usp52, 1200014O24Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103135
VEGA: 10
Homologene: 5918
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 1810014J18Rik, 9030205D12Rik, AD013, A330063D19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 109151
Homologene: 11844
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F32S1, D7H15F37S1, jdf2, rjs, D15F32S1h
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Focad
Name: focadhesin
Synonyms: BC057079
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230393
Homologene: 9842
Vti1a
Name: vesicle transport through interaction with t-SNAREs 1A
Synonyms: Vti1-rp2, 1110014F16Rik, 1110018K19Rik, 4921537J05Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 53611
VEGA: 19
Homologene: 39963
Alkbh5
Name: alkB homolog 5, RNA demethylase
Synonyms: Abh5, Ofoxd
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268420
Homologene: 9818
Tomm70a
Name: translocase of outer mitochondrial membrane 70A
Synonyms: Tomm70a, Tom70, D16Ium22, D16Wsu109e, 2610044B22Rik, D16Ium22e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 28185
VEGA: 16
Homologene: 40112
Mier2
Name: MIER family member 2
Synonyms: 2700087H15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70427
Homologene: 18941
Mmp2
Name: matrix metallopeptidase 2
Synonyms: GelA, Clg4a, MMP-2, 72kDa type IV collagenase, 72kDa gelatinase, gelatinase A
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17390
HGNC: HGNC:7166
Homologene: 3329
Zfp961
Name: zinc finger protein 961
Synonyms: BC049349, A230105L22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234413
Homologene: 136286
Stk40
Name: serine/threonine kinase 40
Synonyms: 2310004N11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74178
Homologene: 12542
Prdm14
Name: PR domain containing 14
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 383491
Homologene: 11556
Lama2
Name: laminin, alpha 2
Synonyms: merosin, mer
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Clec4b2
Name: C-type lectin domain family 4, member b2
Synonyms: mDCAR1, F830043G12Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 381809
Homologene: 128249
Pdzd8
Name: PDZ domain containing 8
Synonyms: Pdzk8, A630041P07Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107368
VEGA: 19
Homologene: 14879
Fcgbpl1
Name: Fc fragment of IgG binding protein like 1
Synonyms: 9530053A07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 319482
Homologene: 130055
Abcc9
Name: ATP-binding cassette, sub-family C member 9
Synonyms: Sur2, SUR2A, SUR2B
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20928
HGNC: HGNC:60
Homologene: 56521
Cog2
Name: component of oligomeric golgi complex 2
Synonyms: 1190002B08Rik, Cog2, 2700012E02Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76332
HGNC: HGNC:6546
Homologene: 7206
Myo5b
Name: myosin VB
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17919
HGNC: HGNC:7603
Homologene: 49481
Shank1
Name: SH3 and multiple ankyrin repeat domains 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243961
Homologene: 22949
Or8g30
Name: olfactory receptor family 8 subfamily G member 30
Synonyms: MOR171-45, Olfr948, MOR171-51, GA_x6K02T2PVTD-33016899-33015934
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 257912
VEGA: 9
HGNC: HGNC:8484
Homologene: 79377
Ifi44
Name: interferon-induced protein 44
Synonyms: MTAP44, p44, A430056A10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99899
Homologene: 4683
Slc13a1
Name: solute carrier family 13 (sodium/sulfate symporters), member 1
Synonyms: NaSi-1, Nas1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 55961
Homologene: 31893
Hivep3
Name: human immunodeficiency virus type I enhancer binding protein 3
Synonyms: Krc, 2900056N03Rik, Schnurri-3, E030045D18Rik, Shn3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16656
Homologene: 7803
Ankrd6
Name: ankyrin repeat domain 6
Synonyms: diversin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 140577
Homologene: 8967
Coq9
Name: coenzyme Q9
Synonyms: 2310005O14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67914
Homologene: 6477
Tas2r117
Name: taste receptor, type 2, member 117
Synonyms: T2R17, Tas2r17, mGR17, mt2r54
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 353166
Homologene: 130073
Papolb
Name: poly (A) polymerase beta (testis specific)
Synonyms: Papola-ps, TPAP, Plap-ps, Papt
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56522
Homologene: 121622
Klra9
Name: killer cell lectin-like receptor subfamily A, member 9
Synonyms: LY49I1, Ly49I
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16640
Homologene: 110821
Spata1
Name: spermatogenesis associated 1
Synonyms: 4921536I21Rik, SP-2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70951
Homologene: 23356
Mrgprb3
Name: MAS-related GPR, member B3
Synonyms: MrgB3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404238
Homologene: 138632
Nicol1
Name: NELL2 interacting cell ontogeny regulator 1
Synonyms: Gm1673, LOC381633
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381633
Homologene: 134513
Krt79
Name: keratin 79
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223917
Homologene: 89169
Clstn2
Name: calsyntenin 2
Synonyms: CSTN2, 2900042C18Rik, Cst-2, CS2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 64085
Homologene: 49698
Or51f1e
Name: olfactory receptor family 51 subfamily F member 1E
Synonyms: Olfr585, GA_x6K02T2PBJ9-5809085-5810035, MOR14-4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259091
Homologene: 133721
Or7d11
Name: olfactory receptor family 7 subfamily D member 11
Synonyms: GA_x6K02T2PVTD-13795933-13794938, Olfr867, MOR143-2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 257898
HGNC: HGNC:8380
Homologene: 128152
Lrfn1
Name: leucine rich repeat and fibronectin type III domain containing 1
Synonyms: SALM2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 80749
Homologene: 12729
Mfsd3
Name: major facilitator superfamily domain containing 3
Synonyms: 2310010G13Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69572
VEGA: 15
Homologene: 12318
Or14c43
Name: olfactory receptor family 14 subfamily C member 43
Synonyms: MOR221-2, GA_x6K02T2NHDJ-9643949-9642957, Olfr299
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257929
Homologene: 115489
Gpr132
Name: G protein-coupled receptor 132
Synonyms: G2 accumulation, G2a
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56696
VEGA: 12
Homologene: 8350
Gja10
Name: gap junction protein, alpha 10
Synonyms: Cx59, Cx57, connexin-57, Cx-57
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14610
Homologene: 7733
Pole3
Name: polymerase (DNA directed), epsilon 3 (p17 subunit)
Synonyms: 1810034K18Rik, YBL1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 59001
Homologene: 9694
3110070M22Rik
Name: RIKEN cDNA 3110070M22 gene
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 67304
VEGA: 13
Trgv1
Name: T cell receptor gamma, variable 1
Synonyms: Gm16602, Tcrg-V1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 21632
Ighv1-42
Name: immunoglobulin heavy variable V1-42
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 629906
Slc2a6
Name: solute carrier family 2 (facilitated glucose transporter), member 6
Synonyms: F630103L12Rik, Glut6
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227659
Homologene: 69236
Cc2d2b
Name: coiled-coil and C2 domain containing 2B
Synonyms: EG668310
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 668310
Homologene: 141114
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 13,122,421 bp
  • C to T, chromosome 2 at 27,023,160 bp
  • T to C, chromosome 2 at 69,459,503 bp
  • A to T, chromosome 3 at 146,475,323 bp
  • A to T, chromosome 3 at 151,745,899 bp
  • G to T, chromosome 4 at 32,601,905 bp
  • C to A, chromosome 4 at 32,806,419 bp
  • T to A, chromosome 4 at 32,806,420 bp
  • T to C, chromosome 4 at 62,524,063 bp
  • C to T, chromosome 4 at 88,230,476 bp
  • T to A, chromosome 4 at 120,095,995 bp
  • T to A, chromosome 4 at 126,137,812 bp
  • G to A, chromosome 5 at 33,983,579 bp
  • C to A, chromosome 5 at 81,689,587 bp
  • T to A, chromosome 5 at 142,528,151 bp
  • T to C, chromosome 6 at 24,097,666 bp
  • C to T, chromosome 6 at 123,201,028 bp
  • T to A, chromosome 6 at 130,179,040 bp
  • T to C, chromosome 6 at 132,803,325 bp
  • T to A, chromosome 6 at 142,679,227 bp
  • C to T, chromosome 7 at 28,137,213 bp
  • T to G, chromosome 7 at 28,459,813 bp
  • T to A, chromosome 7 at 44,356,815 bp
  • T to A, chromosome 7 at 48,643,699 bp
  • A to G, chromosome 7 at 56,135,486 bp
  • T to A, chromosome 7 at 68,004,163 bp
  • T to A, chromosome 7 at 86,465,787 bp
  • C to A, chromosome 7 at 92,658,299 bp
  • A to T, chromosome 7 at 103,098,355 bp
  • A to G, chromosome 8 at 71,968,678 bp
  • A to C, chromosome 8 at 91,042,951 bp
  • G to A, chromosome 8 at 92,836,917 bp
  • G to A, chromosome 8 at 94,850,552 bp
  • A to G, chromosome 8 at 124,546,691 bp
  • A to T, chromosome 9 at 20,055,374 bp
  • C to A, chromosome 9 at 39,319,019 bp
  • A to T, chromosome 9 at 97,469,822 bp
  • T to G, chromosome 10 at 26,981,629 bp
  • C to A, chromosome 10 at 79,540,839 bp
  • A to G, chromosome 10 at 128,315,637 bp
  • G to A, chromosome 11 at 60,538,555 bp
  • T to A, chromosome 12 at 112,852,210 bp
  • T to A, chromosome 12 at 114,937,535 bp
  • A to T, chromosome 12 at 116,139,199 bp
  • T to C, chromosome 13 at 19,340,020 bp
  • T to C, chromosome 13 at 24,115,545 bp
  • C to G, chromosome 13 at 119,488,144 bp
  • T to A, chromosome 15 at 76,703,149 bp
  • T to C, chromosome 15 at 101,931,879 bp
  • T to C, chromosome 16 at 57,138,081 bp
  • A to T, chromosome 18 at 74,676,685 bp
  • A to G, chromosome 19 at 40,816,289 bp
  • A to T, chromosome 19 at 55,499,241 bp
  • A to G, chromosome 19 at 59,301,397 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6902 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045032-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.