Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR6932Btlr/Mmmh
Stock Number:
045047-MU
Citation ID:
RRID:MMRRC_045047-MU
Other Names:
R6932 (G1)
Major Collection:

Strain Information

Slc6a2
Name: solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
Synonyms: Slc6a5, NE transporter, NET, norepinephrine transporter
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20538
Homologene: 816
Omd
Name: osteomodulin
Synonyms: osteoadherin, SLRR2C, OSAD
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 27047
VEGA: 13
HGNC: HGNC:8134
Homologene: 3677
Adk
Name: adenosine kinase
Synonyms: AK, 5033405D03Rik, 2310026J05Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 11534
VEGA: 14
HGNC: HGNC:257
Homologene: 4891
Ttc3
Name: tetratricopeptide repeat domain 3
Synonyms: TPRD, D16Ium21, 2610202A04Rik, D16Ium21e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 22129
Homologene: 2487
Polk
Name: polymerase (DNA directed), kappa
Synonyms: Dinb1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 27015
VEGA: 13
HGNC: HGNC:9183
Homologene: 32140
Luzp1
Name: leucine zipper protein 1
Synonyms: Luzp, 2700072H04Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269593
Homologene: 11545
Snd1
Name: staphylococcal nuclease and tudor domain containing 1
Synonyms: p100 co-activator, Tudor-SN
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56463
Homologene: 8665
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 20,562,451 bp
  • A to G, chromosome 1 at 133,680,158 bp
  • A to G, chromosome 1 at 162,639,346 bp
  • G to A, chromosome 1 at 174,089,750 bp
  • G to A, chromosome 1 at 176,761,437 bp
  • T to C, chromosome 2 at 11,786,243 bp
  • T to C, chromosome 2 at 30,978,928 bp
  • T to A, chromosome 2 at 69,732,411 bp
  • C to T, chromosome 2 at 80,331,336 bp
  • C to G, chromosome 2 at 86,786,155 bp
  • A to T, chromosome 2 at 140,419,913 bp
  • G to A, chromosome 2 at 150,473,411 bp
  • A to G, chromosome 2 at 153,942,627 bp
  • T to C, chromosome 3 at 28,717,519 bp
  • T to C, chromosome 3 at 89,272,784 bp
  • T to C, chromosome 3 at 127,559,632 bp
  • C to T, chromosome 3 at 131,298,296 bp
  • T to G, chromosome 3 at 131,599,971 bp
  • C to T, chromosome 4 at 136,540,813 bp
  • T to A, chromosome 4 at 137,322,621 bp
  • C to T, chromosome 4 at 141,841,568 bp
  • A to G, chromosome 5 at 3,851,395 bp
  • T to C, chromosome 5 at 21,985,857 bp
  • A to C, chromosome 5 at 30,917,077 bp
  • A to G, chromosome 5 at 35,707,434 bp
  • T to A, chromosome 5 at 45,532,901 bp
  • A to T, chromosome 5 at 115,112,272 bp
  • C to G, chromosome 5 at 124,821,450 bp
  • A to T, chromosome 6 at 28,626,101 bp
  • T to A, chromosome 6 at 43,274,417 bp
  • A to G, chromosome 6 at 70,773,440 bp
  • T to C, chromosome 6 at 85,341,558 bp
  • A to G, chromosome 6 at 121,252,514 bp
  • G to T, chromosome 7 at 4,633,292 bp
  • G to C, chromosome 7 at 24,638,433 bp
  • C to A, chromosome 7 at 35,452,511 bp
  • C to T, chromosome 7 at 45,589,321 bp
  • T to C, chromosome 7 at 79,143,301 bp
  • T to A, chromosome 7 at 101,277,414 bp
  • G to T, chromosome 7 at 106,844,802 bp
  • T to C, chromosome 7 at 141,163,183 bp
  • CA to CAA, chromosome 8 at 13,734,865 bp
  • A to G, chromosome 8 at 92,996,025 bp
  • A to T, chromosome 8 at 109,552,675 bp
  • A to T, chromosome 9 at 44,829,261 bp
  • A to G, chromosome 9 at 106,437,627 bp
  • C to T, chromosome 10 at 14,128,501 bp
  • A to G, chromosome 10 at 20,963,691 bp
  • A to G, chromosome 10 at 53,620,203 bp
  • G to T, chromosome 10 at 127,710,458 bp
  • A to T, chromosome 10 at 128,791,654 bp
  • G to T, chromosome 11 at 60,499,494 bp
  • G to T, chromosome 11 at 95,763,841 bp
  • A to T, chromosome 11 at 103,242,132 bp
  • C to A, chromosome 11 at 118,060,079 bp
  • A to G, chromosome 11 at 119,208,916 bp
  • A to T, chromosome 12 at 81,379,200 bp
  • A to G, chromosome 12 at 98,771,077 bp
  • A to G, chromosome 12 at 113,770,072 bp
  • T to A, chromosome 13 at 49,590,234 bp
  • A to G, chromosome 13 at 52,612,459 bp
  • A to T, chromosome 13 at 67,040,827 bp
  • T to A, chromosome 13 at 96,516,681 bp
  • A to G, chromosome 14 at 21,076,308 bp
  • T to A, chromosome 14 at 31,287,776 bp
  • A to G, chromosome 14 at 44,288,188 bp
  • T to A, chromosome 14 at 46,853,722 bp
  • A to T, chromosome 14 at 50,891,916 bp
  • A to G, chromosome 15 at 39,097,589 bp
  • C to A, chromosome 16 at 29,281,951 bp
  • A to G, chromosome 16 at 94,443,453 bp
  • C to T, chromosome 17 at 14,001,663 bp
  • G to T, chromosome 17 at 28,329,450 bp
  • G to T, chromosome 17 at 57,302,330 bp
  • T to A, chromosome 17 at 73,922,562 bp
  • T to G, chromosome 18 at 31,666,354 bp
  • A to G, chromosome 18 at 77,948,609 bp
  • A to T, chromosome 19 at 4,264,420 bp
  • T to A, chromosome 19 at 5,480,245 bp
  • G to T, chromosome 19 at 10,219,560 bp
  • A to T, chromosome 19 at 16,678,075 bp
  • C to T, chromosome 19 at 32,142,793 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6932 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045047-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.