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Strain Name:
C57BL/6J-MtgxR7031Btlr/Mmmh
Stock Number:
045132-MU
Citation ID:
RRID:MMRRC_045132-MU
Other Names:
R7031 (G1)
Major Collection:

Strain Information

Ptk2
Name: PTK2 protein tyrosine kinase 2
Synonyms: Fadk, FAK, FRNK
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14083
VEGA: 15
HGNC: HGNC:9611
Homologene: 7314
Ccdc88c
Name: coiled-coil domain containing 88C
Synonyms: Daple, 0610010D24Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68339
VEGA: 12
Homologene: 18903
Ggnbp2
Name: gametogenetin binding protein 2
Synonyms: DIF-3, Zfp403, D330017P12Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217039
Homologene: 11750
Rgs4
Name: regulator of G-protein signaling 4
Synonyms: ESTM50, ESTM48
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19736
Homologene: 4100
Api5
Name: apoptosis inhibitor 5
Synonyms: AAC-11
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11800
HGNC: HGNC:594
Homologene: 4809
Trpc4ap
Name: transient receptor potential cation channel, subfamily C, member 4 associated protein
Synonyms: Trp4-associated protein TAP1, Trrp4ap, D2Ertd113e, 4833429F06Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56407
Homologene: 9224
Cry1
Name: cryptochrome circadian regulator 1
Synonyms: Phll1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12952
VEGA: 10
HGNC: HGNC:2384
Homologene: 7042
Dhx15
Name: DEAH-box helicase 15
Synonyms: mDEAH9, DBP1, HRH2, Ddx15, DEAH (Asp-Glu-Ala-His) box polypeptide 15
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13204
HGNC: HGNC:2738
Homologene: 1040
Hmgxb4
Name: HMG box domain containing 4
Synonyms: 4733401K04Rik, Hmgb2l1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 70823
HGNC: HGNC:5003
Homologene: 4007
Gpbp1l1
Name: GC-rich promoter binding protein 1-like 1
Synonyms: 5330440M15Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 77110
Homologene: 84840
Gchfr
Name: GTP cyclohydrolase I feedback regulator
Synonyms: P35, 2010323F13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320415
HGNC: HGNC:4194
Homologene: 3849
Drd3
Name: dopamine receptor D3
Synonyms: D3R, D3 receptor
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13490
VEGA: 16
HGNC: HGNC:3024
Homologene: 623
Cuzd1
Name: CUB and zona pellucida-like domains 1
Synonyms: UTCZP, UO-44, ERG-1, Itmap1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16433
Homologene: 7389
Dcbld1
Name: discoidin, CUB and LCCL domain containing 1
Synonyms: 4631413K11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66686
Homologene: 12010
Acsl3
Name: acyl-CoA synthetase long-chain family member 3
Synonyms: 2610510B12Rik, C85929, Facl3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74205
HGNC: HGNC:3570
Homologene: 3278
Ebf1
Name: early B cell factor 1
Synonyms: Olf-1, O/E-1, Olf1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13591
HGNC: HGNC:3126
Homologene: 7297
Abca13
Name: ATP-binding cassette, sub-family A member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268379
Homologene: 27991
Epha5
Name: Eph receptor A5
Synonyms: Cek7, bsk, Els1, Rek7, Hek7, Ehk1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13839
HGNC: HGNC:3389
Homologene: 55824
Or55b3
Name: olfactory receptor family 55 subfamily B member 3
Synonyms: GA_x6K02T2PBJ9-5199377-5198367, MOR42-2, Olfr543
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257947
Homologene: 81631
Rb1cc1
Name: RB1-inducible coiled-coil 1
Synonyms: LaXp180, 2900055E04Rik, Cc1, 5930404L04Rik, Fip200
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12421
Homologene: 7659
Cntnap4
Name: contactin associated protein-like 4
Synonyms: Caspr4, E130114F09Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 170571
Homologene: 24912
Stard9
Name: StAR related lipid transfer domain containing 9
Synonyms: N-3 kinesin, Kif16a, 4831403C07Rik, E230025N21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668880
Homologene: 130712
Lipm
Name: lipase, family member M
Synonyms: 4632427C23Rik, Lipl3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 78753
VEGA: 19
Homologene: 28267
Trpc3
Name: transient receptor potential cation channel, subfamily C, member 3
Synonyms: Trp3, Trrp3, Trcp3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22065
Homologene: 20708
Vmn2r111
Name: vomeronasal 2, receptor 111
Synonyms: EG210876
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 210876
Homologene: 86604
Cfap96
Name: cilia and flagella associated protein 96
Synonyms: 1700029J07Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 69479
Homologene: 45977
Gpat2
Name: glycerol-3-phosphate acyltransferase 2, mitochondrial
Synonyms: Gpat2, A530057A03Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 215456
Homologene: 19037
Dhh
Name: desert hedgehog
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 13363
VEGA: 15
HGNC: HGNC:2865
Homologene: 22431
Mug1
Name: murinoglobulin 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17836
HGNC: HGNC:9750
Homologene: 136663
Brme1
Name: break repair meiotic recombinase recruitment factor 1
Synonyms: Meiok21, 4930432K21Rik, Mamerr
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74666
Homologene: 11525
Or2ad1
Name: olfactory receptor family 2 subfamily AD member 1
Synonyms: GA_x6K02T2QHY8-12104556-12105500, MOR256-15, Olfr1368
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 258527
Homologene: 105156
Vmn1r56
Name: vomeronasal 1 receptor 56
Synonyms: V3R3, V1rd3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 81015
Homologene: 41799
Or5m3
Name: olfactory receptor family 5 subfamily M member 3
Synonyms: GA_x6K02T2Q125-47485813-47486745, MOR199-1, Olfr1032
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258572
Homologene: 17299
Mark1
Name: MAP/microtubule affinity regulating kinase 1
Synonyms: Emk3, B930025N23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226778
HGNC: HGNC:6896
Homologene: 49552
Fam83d
Name: family with sequence similarity 83, member D
Synonyms: 2310007D09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71878
Homologene: 23715
Serpinf1
Name: serine (or cysteine) peptidase inhibitor, clade F, member 1
Synonyms: EPC-1, Pedf, Sdf3, pigment epithelium derived factor, Pedfl
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20317
HGNC: HGNC:8824
Homologene: 1965
Ing2
Name: inhibitor of growth family, member 2
Synonyms: P33ING2, 2810011M06Rik, ING2, Ing1l
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 69260
HGNC: HGNC:6063
Homologene: 20388
Sel1l2
Name: sel-1 suppressor of lin-12-like 2 (C. elegans)
Synonyms: LOC228684
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228684
Homologene: 16802
Mlip
Name: muscular LMNA-interacting protein
Synonyms: 2310046A06Rik, cardiac ISL1-interacting protein, CIP
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69642
Homologene: 90445
Zfp664
Name: zinc finger protein 664
Synonyms: D930038J03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269704
Homologene: 65046
Epx
Name: eosinophil peroxidase
Synonyms: EPO
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13861
HGNC: HGNC:3423
Homologene: 20144
Gnal
Name: guanine nucleotide binding protein, alpha stimulating, olfactory type
Synonyms: G alpha 10, Golf, Gna10, 9630020G10Rik, 2610011C15Rik, Galphaolf
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 14680
VEGA: 18
HGNC: HGNC:4388
Homologene: 68222
Acadsb
Name: acyl-Coenzyme A dehydrogenase, short/branched chain
Synonyms: 1300003O09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66885
HGNC: HGNC:91
Homologene: 1216
Itfg2
Name: integrin alpha FG-GAP repeat containing 2
Synonyms: 2700050P07Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101142
Homologene: 10211
Vat1l
Name: vesicle amine transport protein 1 like
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 270097
Homologene: 10855
Klhl22
Name: kelch-like 22
Synonyms: 2610318I18Rik, Kelchl
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224023
Homologene: 23784
4931414P19Rik
Name: RIKEN cDNA 4931414P19 gene
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 74359
VEGA: 14
Homologene: 11078
Ly96
Name: lymphocyte antigen 96
Synonyms: MD-2, MD2, ESOP-1, myeloid differentiation factor-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17087
Homologene: 9109
Sgo2b
Name: shugoshin 2B
Synonyms: Gm4975, Sgol2b
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244495
Homologene: 51867
Igkv4-91
Name: immunoglobulin kappa chain variable 4-91
Synonyms: ENSMUSG00000056850, Gm10879
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 434033
Trgv6
Name: T cell receptor gamma, variable 6
Synonyms: Tcrg-V6
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 21640
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 6,238,466 bp
  • A to T, chromosome 1 at 16,688,563 bp
  • T to A, chromosome 1 at 78,688,283 bp
  • T to C, chromosome 1 at 169,743,767 bp
  • C to T, chromosome 1 at 184,912,632 bp
  • C to T, chromosome 2 at 86,008,595 bp
  • G to A, chromosome 2 at 94,425,616 bp
  • T to A, chromosome 2 at 119,169,755 bp
  • T to C, chromosome 2 at 120,700,450 bp
  • A to G, chromosome 2 at 127,435,475 bp
  • T to A, chromosome 2 at 140,340,123 bp
  • C to A, chromosome 2 at 155,692,215 bp
  • T to A, chromosome 2 at 158,785,307 bp
  • A to C, chromosome 3 at 36,621,310 bp
  • C to T, chromosome 4 at 116,592,848 bp
  • T to C, chromosome 5 at 52,184,589 bp
  • T to C, chromosome 5 at 84,142,300 bp
  • A to G, chromosome 5 at 124,886,006 bp
  • G to T, chromosome 6 at 68,768,558 bp
  • A to T, chromosome 6 at 121,838,714 bp
  • A to G, chromosome 6 at 128,416,054 bp
  • T to A, chromosome 7 at 5,196,262 bp
  • T to A, chromosome 7 at 102,477,850 bp
  • A to T, chromosome 7 at 131,308,851 bp
  • A to G, chromosome 7 at 131,443,637 bp
  • T to C, chromosome 8 at 45,968,103 bp
  • T to C, chromosome 8 at 47,668,823 bp
  • C to T, chromosome 8 at 63,940,044 bp
  • C to T, chromosome 8 at 75,029,572 bp
  • C to A, chromosome 8 at 84,166,684 bp
  • C to A, chromosome 8 at 112,858,242 bp
  • A to G, chromosome 8 at 114,271,432 bp
  • T to A, chromosome 9 at 77,138,553 bp
  • A to T, chromosome 10 at 52,290,889 bp
  • A to G, chromosome 10 at 85,148,662 bp
  • C to T, chromosome 11 at 9,621,892 bp
  • A to G, chromosome 11 at 44,621,968 bp
  • T to C, chromosome 11 at 75,410,196 bp
  • A to G, chromosome 11 at 84,860,641 bp
  • T to A, chromosome 11 at 87,875,523 bp
  • T to C, chromosome 12 at 100,945,064 bp
  • G to A, chromosome 13 at 19,190,440 bp
  • C to T, chromosome 13 at 21,143,000 bp
  • T to C, chromosome 14 at 54,595,601 bp
  • G to A, chromosome 15 at 73,221,809 bp
  • C to T, chromosome 15 at 98,894,026 bp
  • T to C, chromosome 16 at 17,777,026 bp
  • T to A, chromosome 16 at 43,762,498 bp
  • T to C, chromosome 17 at 22,571,245 bp
  • G to A, chromosome 18 at 67,222,588 bp
  • A to T, chromosome 19 at 34,116,471 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7031 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045132-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.