Strain Name:
C57BL/6J-MtgxR7047Btlr/Mmmh
Stock Number:
045145-MU
Citation ID:
RRID:MMRRC_045145-MU
Other Names:
R7047 (G1)
Major Collection:

Strain Information

Wnt5b
Name: wingless-type MMTV integration site family, member 5B
Synonyms: Wnt-5b
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22419
Homologene: 22530
Adora2a
Name: adenosine A2a receptor
Synonyms: A2AAR, A2aR, ARA2A, A2a, Rs, AA2AR
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11540
VEGA: 10
HGNC: HGNC:263
Homologene: 20166
Dbh
Name: dopamine beta hydroxylase
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13166
HGNC: HGNC:2689
Homologene: 615
Kat2b
Name: K(lysine) acetyltransferase 2B
Synonyms: Pcaf, A930006P13Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18519
HGNC: HGNC:8638
Homologene: 20834
Cep55
Name: centrosomal protein 55
Synonyms: 1200008O12Rik, 2700032M20Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 74107
VEGA: 19
HGNC: HGNC:1161
Homologene: 10019
Phf12
Name: PHD finger protein 12
Synonyms: PF1, 2410142K10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268448
Homologene: 10841
Arfgef2
Name: ADP ribosylation factor guanine nucleotide exchange factor 2
Synonyms: BIG2, E230011G24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99371
Homologene: 111880
Ints1
Name: integrator complex subunit 1
Synonyms: 1110015K06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68510
Homologene: 53111
Anapc1
Name: anaphase promoting complex subunit 1
Synonyms: tsg24, Mcpr, 2610021O03Rik, Apc1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17222
Homologene: 7414
Hspa5
Name: heat shock protein 5
Synonyms: baffled, D2Wsu141e, Grp78, D2Wsu17e, Hsce70, mBiP, Bip, XAP-1 antigen, 78kDa, Sez7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14828
HGNC: HGNC:5238
Homologene: 3908
Msr1
Name: macrophage scavenger receptor 1
Synonyms: SR-AII, MRS-A, Scara1, Scvr, SR-AI, MSR-A
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20288
HGNC: HGNC:7376
Homologene: 12822
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Pan3
Name: PAN3 poly(A) specific ribonuclease subunit
Synonyms: 2700050F09Rik, A430027N15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72587
Homologene: 6372
Dzip3
Name: DAZ interacting protein 3, zinc finger
Synonyms: 2A-HUB, 6430549P11Rik, 2310047C04Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224170
Homologene: 8771
Grhl3
Name: grainyhead like transcription factor 3
Synonyms: ct, Get1, Som
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230824
Homologene: 18864
Ext2
Name: exostosin glycosyltransferase 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14043
HGNC: HGNC:3513
Homologene: 345
Rab40c
Name: Rab40C, member RAS oncogene family
Synonyms: RAR3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224624
Homologene: 10907
Kat6a
Name: K(lysine) acetyltransferase 6A
Synonyms: 9930021N24Rik, MOZ, Myst3, Zfp220
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244349
Homologene: 4924
Sh2d3c
Name: SH2 domain containing 3C
Synonyms: Shep1, SH2-containing Eph receptor-binding protein 1, Nsp3, Cas/HEF1-associated signal transducer, Chat
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27387
Homologene: 69145
Tnfrsf19
Name: tumor necrosis factor receptor superfamily, member 19
Synonyms: Troy, TAJ, TAJ-ALPHA, TRADE
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 29820
VEGA: 14
Homologene: 8481
Ift172
Name: intraflagellar transport 172
Synonyms: wim, 4930553F24Rik, avc1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67661
Homologene: 15202
Rhbdf2
Name: rhomboid 5 homolog 2
Synonyms: 4732465I17Rik, cub, Uncv, Rhbdl6, iRhom2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217344
Homologene: 11612
Capn11
Name: calpain 11
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268958
HGNC: HGNC:1478
Homologene: 21392
Maml2
Name: mastermind like transcriptional coactivator 2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270118
Homologene: 134147
Plcd4
Name: phospholipase C, delta 4
Synonyms: 4921507K24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18802
HGNC: HGNC:9062
Homologene: 88782
Nlgn1
Name: neuroligin 1
Synonyms: NL1, Nlg1, 6330415N05Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192167
Homologene: 56690
Gpr63
Name: G protein-coupled receptor 63
Synonyms: PSP24beta
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 81006
Homologene: 12759
Stab2
Name: stabilin 2
Synonyms: STAB-2, FEEL-2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 192188
Homologene: 23022
Capn7
Name: calpain 7
Synonyms: PalBH
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12339
HGNC: HGNC:1484
Homologene: 7651
Ptgfr
Name: prostaglandin F receptor
Synonyms: PGF, FP
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19220
HGNC: HGNC:9600
Homologene: 741
Adcy5
Name: adenylate cyclase 5
Synonyms: AC5
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224129
VEGA: 16
HGNC: HGNC:236
Homologene: 11213
Rasal3
Name: RAS protein activator like 3
Synonyms: A430107D22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320484
Homologene: 18901
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50720
L3mbtl4
Name: L3MBTL4 histone methyl-lysine binding protein
Synonyms: A730037L19Rik, D930040M24Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320858
Homologene: 114383
Filip1
Name: filamin A interacting protein 1
Synonyms: 5730485H21Rik, FILIP
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70598
Homologene: 6700
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
Ms4a15
Name: membrane-spanning 4-domains, subfamily A, member 15
Synonyms: E530011F12Rik, LOC383468, Gm1286
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 545279
Homologene: 27391
Tll2
Name: tolloid-like 2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 24087
VEGA: 19
Homologene: 56545
Emilin1
Name: elastin microfibril interfacer 1
Synonyms: 5830419M17Rik, gp115, EMILIN-1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100952
Homologene: 5117
Smarca2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Synonyms: brm, 2610209L14Rik, Snf2l2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 67155
Homologene: 2308
3425401B19Rik
Name: RIKEN cDNA 3425401B19 gene
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100504518
VEGA: 14
Homologene: 54908
Tmbim7
Name: transmembrane BAX inhibitor motif containing 7
Synonyms: 4930511M11Rik, Tmbim1b, Lfg5, 4930403J02Rik, 4930500J03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75010
Homologene: 81927
Sned1
Name: sushi, nidogen and EGF-like domains 1
Synonyms: 6720455I24Rik, D430044C15Rik, Snep
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 208777
Homologene: 14708
Mocs1
Name: molybdenum cofactor synthesis 1
Synonyms: 3110045D15Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 56738
HGNC: HGNC:7190
Homologene: 4343
Or4c113
Name: olfactory receptor family 4 subfamily C member 113
Synonyms: MOR233-12, GA_x6K02T2Q125-50536041-50535106, Olfr1218
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258815
Homologene: 73986
Tcte1
Name: t-complex-associated testis expressed 1
Synonyms: D17Sil1, Tcte-1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21645
VEGA: 17
Homologene: 8434
Garin1b
Name: golgi associated RAB2 interactor 1B
Synonyms: Fam71f1, LOC330277
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330277
Homologene: 13077
Mixl1
Name: Mix paired-like homeobox
Synonyms: Mml
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 27217
Homologene: 8445
Nsmce1
Name: NSE1 homolog, SMC5-SMC6 complex component
Synonyms: 2510027N19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67711
Homologene: 41672
Pcyox1
Name: prenylcysteine oxidase 1
Synonyms: Pcly, PCL1, 1200015P13Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66881
Homologene: 9458
Disp1
Name: dispatched RND transporter family member 1
Synonyms: DispA, 1190008H24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68897
Homologene: 14133
Spata31d1b
Name: spermatogenesis associated 31 subfamily D, member 1B
Synonyms: Gm4934, Fam75d1b
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238662
VEGA: 13
Or51v15-ps1
Name: olfactory receptor family 51 subfamily V member 15, pseudogene 1
Synonyms: MOR4-4_p, MOR4-3P, GA_x6K02T2PBJ9-6352653-6351709, Olfr621-ps1, EG667639
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 667639
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 74,551,989 bp
  • A to T, chromosome 1 at 93,285,818 bp
  • A to G, chromosome 1 at 180,696,618 bp
  • C to A, chromosome 1 at 183,087,466 bp
  • T to A, chromosome 2 at 27,165,610 bp
  • A to G, chromosome 2 at 27,928,084 bp
  • T to C, chromosome 2 at 32,721,160 bp
  • C to T, chromosome 2 at 34,773,192 bp
  • A to T, chromosome 2 at 89,055,146 bp
  • A to G, chromosome 2 at 93,739,657 bp
  • A to C, chromosome 2 at 128,615,430 bp
  • T to A, chromosome 2 at 166,851,945 bp
  • A to C, chromosome 3 at 25,436,035 bp
  • A to T, chromosome 3 at 151,835,541 bp
  • G to T, chromosome 4 at 25,007,320 bp
  • T to C, chromosome 4 at 135,549,240 bp
  • A to T, chromosome 5 at 3,670,112 bp
  • A to G, chromosome 5 at 30,917,078 bp
  • G to T, chromosome 5 at 31,275,894 bp
  • A to C, chromosome 5 at 139,758,471 bp
  • G to A, chromosome 5 at 147,546,365 bp
  • T to A, chromosome 6 at 29,323,810 bp
  • G to T, chromosome 6 at 86,388,909 bp
  • T to A, chromosome 6 at 119,448,256 bp
  • A to G, chromosome 7 at 103,629,711 bp
  • T to A, chromosome 7 at 104,768,433 bp
  • C to A, chromosome 7 at 125,491,434 bp
  • A to G, chromosome 8 at 22,938,538 bp
  • G to A, chromosome 8 at 39,642,616 bp
  • T to C, chromosome 9 at 13,620,881 bp
  • T to A, chromosome 9 at 79,853,634 bp
  • A to G, chromosome 10 at 75,326,311 bp
  • C to T, chromosome 10 at 86,858,152 bp
  • T to C, chromosome 11 at 78,013,273 bp
  • A to G, chromosome 11 at 116,603,651 bp
  • T to A, chromosome 13 at 11,824,400 bp
  • T to C, chromosome 13 at 59,712,435 bp
  • C to T, chromosome 14 at 31,336,685 bp
  • A to T, chromosome 14 at 32,660,174 bp
  • A to T, chromosome 14 at 61,005,218 bp
  • A to T, chromosome 14 at 61,213,002 bp
  • T to A, chromosome 16 at 35,267,215 bp
  • A to T, chromosome 16 at 48,982,126 bp
  • A to C, chromosome 17 at 25,919,484 bp
  • T to A, chromosome 17 at 32,396,484 bp
  • A to T, chromosome 17 at 45,533,368 bp
  • G to T, chromosome 17 at 45,638,696 bp
  • T to C, chromosome 17 at 49,452,859 bp
  • A to G, chromosome 17 at 53,663,569 bp
  • G to T, chromosome 17 at 68,461,566 bp
  • T to G, chromosome 19 at 10,984,872 bp
  • C to T, chromosome 19 at 26,669,155 bp
  • T to A, chromosome 19 at 38,060,091 bp
  • C to T, chromosome 19 at 41,086,240 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7047 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045145-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.