Strain Name:
C57BL/6J-MtgxR7085Btlr/Mmmh
Stock Number:
045179-MU
Citation ID:
RRID:MMRRC_045179-MU
Other Names:
R7085 (G1)
Major Collection:

Strain Information

Rtn4rl1
Name: reticulon 4 receptor-like 1
Synonyms: Ngrh2, Ngrl2, Ngr3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237847
Homologene: 18611
Bclaf1
Name: BCL2-associated transcription factor 1
Synonyms: 2610102K23Rik, 5730534O06Rik, 2810454G14Rik, 2700025J07Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 72567
Homologene: 8832
Prex2
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Synonyms: 6230420N16Rik, Depdc2, C030045D06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 109294
Homologene: 23523
Polr2a
Name: polymerase (RNA) II (DNA directed) polypeptide A
Synonyms: 220kDa, Rpo2-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20020
HGNC: HGNC:9187
Homologene: 721
Btaf1
Name: B-TFIID TATA-box binding protein associated factor 1
Synonyms: E430027O22Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107182
Homologene: 31978
Ddx1
Name: DEAD box helicase 1
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104721
VEGA: 12
HGNC: HGNC:2734
Homologene: 3627
Sbno1
Name: strawberry notch 1
Synonyms: 9330180L10Rik, sno
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243272
Homologene: 10055
Fry
Name: FRY microtubule binding protein
Synonyms: cg003, 9330186A19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320365
Homologene: 113770
Smchd1
Name: SMC hinge domain containing 1
Synonyms: MommeD1, 4931400A14Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74355
Homologene: 23665
Supt5
Name: suppressor of Ty 5, DSIF elongation factor subunit
Synonyms: Spt5, Supt5h
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20924
Homologene: 2384
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: A530081C03Rik, Murr2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17847
Homologene: 40978
Unc13d
Name: unc-13 homolog D
Synonyms: Jinx, 2610108D09Rik, Munc13-4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70450
Homologene: 26714
Laptm4a
Name: lysosomal-associated protein transmembrane 4A
Synonyms: Mtrp
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 17775
HGNC: HGNC:6924
Homologene: 7427
Soat1
Name: sterol O-acyltransferase 1
Synonyms: ACAT-1, Acact, hid, 8430426K15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20652
Homologene: 2333
Mafa
Name: MAF bZIP transcription factor A
Synonyms: RIPE3b1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 378435
VEGA: 15
Homologene: 65867
Unc45a
Name: unc-45 myosin chaperone A
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101869
Homologene: 32423
Lmbr1
Name: limb region 1
Synonyms: C79130, 1110048D14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56873
Homologene: 49706
Drap1
Name: DR1 associated protein 1
Synonyms: 2310074H19Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66556
HGNC: HGNC:3019
Homologene: 4703
Kank4
Name: KN motif and ankyrin repeat domains 4
Synonyms: Ankrd38
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242553
Homologene: 18244
Runx2
Name: runt related transcription factor 2
Synonyms: Cbfa1, Pebpa2a, AML3, polyomavirus enhancer binding factor 2 (PEBP2), PEBP2 alpha A, Osf2, SL3-3 enhancer factor 1, PEBP2aA
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12393
Homologene: 68389
Lnx1
Name: ligand of numb-protein X 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16924
HGNC: HGNC:6657
Homologene: 7819
Muc16
Name: mucin 16
Synonyms: 1110008I14Rik, Gm21044, LOC385009
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73732
Homologene: 141193
Hacd3
Name: 3-hydroxyacyl-CoA dehydratase 3
Synonyms: Ptplad1, B-ind1, Hspc121
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 57874
VEGA: 9
Homologene: 9494
Cntrl
Name: centriolin
Synonyms: b2b1468Clo, Ma2a8, 6720467O09Rik, IB3/5, Cep110, Cep1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26920
HGNC: HGNC:1858
Homologene: 38260
Med23
Name: mediator complex subunit 23
Synonyms: ESTM7, Sur2, Crsp3, X83317, sno, 3000002A17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70208
HGNC: HGNC:2372
Homologene: 3552
Piezo1
Name: piezo-type mechanosensitive ion channel component 1
Synonyms: Fam38a, Piezo1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234839
Homologene: 124356
Nbas
Name: neuroblastoma amplified sequence
Synonyms: 4933425L03Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 71169
VEGA: 12
Homologene: 41073
Blzf1
Name: basic leucine zipper nuclear factor 1
Synonyms: Jem-1, Blzf1l, Golgin-45, 1700030G05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66352
HGNC: HGNC:1065
Homologene: 31187
Gprc5b
Name: G protein-coupled receptor, family C, group 5, member B
Synonyms: hypothetical protein, clone 2-63
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 64297
Homologene: 9435
Me2
Name: malic enzyme 2, NAD(+)-dependent, mitochondrial
Synonyms: D030040L20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 107029
VEGA: 18
HGNC: HGNC:6984
Homologene: 37615
Dnhd1
Name: dynein heavy chain domain 1
Synonyms: 8030491N06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77505
Homologene: 131117
Reln
Name: reelin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19699
HGNC: HGNC:9957
Homologene: 3699
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: hy3, hyrh, hy-3, 1700034M11Rik, 4930545D19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244653
Homologene: 52118
Cpa1
Name: carboxypeptidase A1, pancreatic
Synonyms: 0910001L12Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 109697
HGNC: HGNC:2296
Homologene: 55609
Cntn3
Name: contactin 3
Synonyms: Pang
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18488
HGNC: HGNC:2173
Homologene: 7461
Afap1l1
Name: actin filament associated protein 1-like 1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 106877
Homologene: 18728
Chd3
Name: chromodomain helicase DNA binding protein 3
Synonyms: Chd7, Prp7, Mi-2 alpha, 2600010P09Rik, Prp9-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216848
HGNC: HGNC:1918
Homologene: 62693
Emilin2
Name: elastin microfibril interfacer 2
Synonyms: basilin, FOAP-10
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 246707
VEGA: 17
Homologene: 36483
D130043K22Rik
Name: RIKEN cDNA D130043K22 gene
Synonyms: Kiaa0319
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 210108
Homologene: 8878
Dock3
Name: dedicator of cyto-kinesis 3
Synonyms: PBP, Moca
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208869
HGNC: HGNC:2989
Homologene: 21030
Spata31e2
Name: spermatogenesis associated 31 subfamily E member 2
Synonyms: 4931408C20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210940
Homologene: 86827
Fbxo44
Name: F-box protein 44
Synonyms: Fbx6a, FBX30, FBG3, Fbxo6a
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230903
Homologene: 13232
Plcb3
Name: phospholipase C, beta 3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18797
VEGA: 19
HGNC: HGNC:9056
Homologene: 47960
Ecm2
Name: extracellular matrix protein 2, female organ and adipocyte specific
Synonyms: tenonectin, 9030618O22Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 407800
VEGA: 13
HGNC: HGNC:3154
Homologene: 1064
Abhd18
Name: abhydrolase domain containing 18
Synonyms: 3110057O12Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 269423
Homologene: 105457
Tns1
Name: tensin 1
Synonyms: 1200014E20Rik, E030037J05Rik, 1110018I21Rik, Tns, E030018G17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 21961
Homologene: 11219
Igsf3
Name: immunoglobulin superfamily, member 3
Synonyms: 2810035F16Rik, 1700016K10Rik, 4833439O17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 78908
HGNC: HGNC:5950
Homologene: 1182
Tlr11
Name: toll-like receptor 11
Synonyms: LOC239081
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239081
Homologene: 77905
Atrnl1
Name: attractin like 1
Synonyms: Alp
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226255
VEGA: 19
Homologene: 45809
Gli3
Name: GLI-Kruppel family member GLI3
Synonyms: Bph, brachyphalangy
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14634
HGNC: HGNC:4319
Homologene: 139
Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Synonyms: alpha1E, Cav2.3, Cchra1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12290
HGNC: HGNC:1392
Homologene: 20185
C1qa
Name: complement component 1, q subcomponent, alpha polypeptide
Synonyms: C1q
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12259
HGNC: HGNC:1241
Homologene: 7249
Atp8b5
Name: ATPase, class I, type 8B, member 5
Synonyms: 4930417M19Rik, FetA
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320571
Homologene: 99882
Tmc3
Name: transmembrane channel-like gene family 3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233424
Homologene: 45588
Rsph10b
Name: radial spoke head 10 homolog B (Chlamydomonas)
Synonyms: 4930526H21Rik, Rsph10b2
Type: Gene
Species: Mouse
Chromosome: 5
Homologene: 18321
Ankrd34a
Name: ankyrin repeat domain 34A
Synonyms: Ankrd34
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 545554
Homologene: 82882
Or13c25
Name: olfactory receptor family 13 subfamily C member 25
Synonyms: Olfr272, GA_x6K02T2N78B-7084885-7085844, MOR262-7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 258836
Homologene: 17409
Or6k6
Name: olfactory receptor family 6 subfamily K member 6
Synonyms: Olfr425, GA_x6K02T02K39-452-3, Olfr231, GA_x6K02T2LER7-6-623, Olfr244, GA_x6K02T2P20D-21053942-21054499, MOR105-4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 404222
Homologene: 17363
Krtap16-1
Name: keratin associated protein 16-1
Synonyms: AI450886
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 100504183
Homologene: 99988
9330159F19Rik
Name: RIKEN cDNA 9330159F19 gene
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 212448
VEGA: 10
Homologene: 8804
Vps33b
Name: vacuolar protein sorting 33B
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233405
Homologene: 10261
Ddx49
Name: DEAD box helicase 49
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 49, R27090_2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234374
Homologene: 41308
Or10ag60
Name: olfactory receptor family 10 subfamily AG member 60
Synonyms: MOR264-4, GA_x6K02T2Q125-49112575-49113519, Olfr1130
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258835
Homologene: 133705
Prag1
Name: PEAK1 related kinase activating pseudokinase 1
Synonyms: NACK, D8Ertd82e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244418
Homologene: 18256
Cfd
Name: complement factor D
Synonyms: factor D, DF, D component (adipsin) of complement, Adn
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11537
VEGA: 10
HGNC: HGNC:2771
Homologene: 20453
Flot2
Name: flotillin 2
Synonyms: reggie-2, Esa
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14252
HGNC: HGNC:3758
Homologene: 3293
Tspan2
Name: tetraspanin 2
Synonyms: 6330415F13Rik, B230119D02Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70747
Homologene: 21169
Slc22a22
Name: solute carrier family 22 (organic cation transporter), member 22
Synonyms: OAT-PG, BC026439
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 210463
Homologene: 18166
Slc40a1
Name: solute carrier family 40 (iron-regulated transporter), member 1
Synonyms: Dusg, MTP1, FPN1, Ol5, Pcm, Slc11a3, ferroportin1, metal transporting protein 1, IREG1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 53945
Homologene: 40959
Ido2
Name: indoleamine 2,3-dioxygenase 2
Synonyms: Indol1, Ido2, C230043N17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 209176
Homologene: 48830
H1f11-ps
Name: H1.11 linker histone, pseudogene
Synonyms: Gm6970
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 629389
VEGA: 19
Shisal2b
Name: shisa like 2B
Synonyms: Fam159b, A930021C24Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 77803
VEGA: 13
Homologene: 19019
Hsd3b9
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 9
Synonyms: Gm4450
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 100043461
Homologene: 104115
Sh3d21
Name: SH3 domain containing 21
Synonyms: 1700029G01Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66938
Homologene: 12057
Or7d11
Name: olfactory receptor family 7 subfamily D member 11
Synonyms: Olfr867, GA_x6K02T2PVTD-13795933-13794938, MOR143-2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 257898
HGNC: HGNC:8380
Homologene: 128152
Or10d5j
Name: olfactory receptor family 10 subfamily D member 5J
Synonyms: MOR224-10, Olfr976, GA_x6K02T2PVTD-33657378-33656440
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258364
VEGA: 9
Homologene: 64863
Evx1
Name: even-skipped homeobox 1
Synonyms: Evx-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14028
HGNC: HGNC:3506
Homologene: 1507
Scn3b
Name: sodium channel, voltage-gated, type III, beta
Synonyms: 4833414B02Rik, 1110001K16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235281
Homologene: 10176
Tapbpl
Name: TAP binding protein-like
Synonyms: TAPBPL-R
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213233
Homologene: 9958
Gm49368
Name: predicted gene, 49368
Type: Gene
Species: Mouse
Chromosome: 7
Tdpoz7
Name: Td and POZ domain containing 7
Synonyms: Gm10697
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 100042761
Homologene: 128308
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 11,098,588 bp
  • A to G, chromosome 1 at 26,683,465 bp
  • T to A, chromosome 1 at 45,911,528 bp
  • G to A, chromosome 1 at 73,925,462 bp
  • A to T, chromosome 1 at 154,473,746 bp
  • A to T, chromosome 1 at 156,432,331 bp
  • T to C, chromosome 1 at 164,302,324 bp
  • T to A, chromosome 1 at 174,117,660 bp
  • T to A, chromosome 2 at 35,165,792 bp
  • T to A, chromosome 2 at 87,607,406 bp
  • T to C, chromosome 3 at 40,916,909 bp
  • T to A, chromosome 3 at 94,072,632 bp
  • A to T, chromosome 3 at 96,598,629 bp
  • T to C, chromosome 3 at 98,450,394 bp
  • C to A, chromosome 3 at 101,455,489 bp
  • C to A, chromosome 3 at 102,760,954 bp
  • A to G, chromosome 4 at 43,361,835 bp
  • C to T, chromosome 4 at 52,910,961 bp
  • T to A, chromosome 4 at 98,779,946 bp
  • T to A, chromosome 4 at 126,163,091 bp
  • T to C, chromosome 4 at 136,897,780 bp
  • T to A, chromosome 4 at 148,158,743 bp
  • C to A, chromosome 5 at 21,915,087 bp
  • A to T, chromosome 5 at 29,361,092 bp
  • G to A, chromosome 5 at 74,628,185 bp
  • G to A, chromosome 5 at 124,381,720 bp
  • A to T, chromosome 5 at 143,949,284 bp
  • A to G, chromosome 5 at 150,438,749 bp
  • A to G, chromosome 6 at 30,643,620 bp
  • T to C, chromosome 6 at 52,316,692 bp
  • A to G, chromosome 6 at 102,165,401 bp
  • T to C, chromosome 6 at 125,226,488 bp
  • T to A, chromosome 7 at 28,331,489 bp
  • A to G, chromosome 7 at 80,276,089 bp
  • A to T, chromosome 7 at 80,326,334 bp
  • A to T, chromosome 7 at 83,622,145 bp
  • T to A, chromosome 7 at 105,715,261 bp
  • A to T, chromosome 7 at 118,983,632 bp
  • A to G, chromosome 7 at 128,126,857 bp
  • T to A, chromosome 8 at 24,558,196 bp
  • A to T, chromosome 8 at 36,104,237 bp
  • G to A, chromosome 8 at 70,302,483 bp
  • A to G, chromosome 8 at 110,603,330 bp
  • A to G, chromosome 8 at 122,490,894 bp
  • T to A, chromosome 9 at 18,644,849 bp
  • G to A, chromosome 9 at 20,054,936 bp
  • C to A, chromosome 9 at 39,956,512 bp
  • T to C, chromosome 9 at 40,277,098 bp
  • A to C, chromosome 9 at 64,998,243 bp
  • A to G, chromosome 9 at 106,901,887 bp
  • T to C, chromosome 10 at 20,322,022 bp
  • T to A, chromosome 10 at 24,870,121 bp
  • T to C, chromosome 10 at 29,224,480 bp
  • T to G, chromosome 10 at 79,892,492 bp
  • A to G, chromosome 11 at 23,363,097 bp
  • T to A, chromosome 11 at 69,369,201 bp
  • A to G, chromosome 11 at 69,743,880 bp
  • A to G, chromosome 11 at 75,265,224 bp
  • G to T, chromosome 11 at 78,058,074 bp
  • T to A, chromosome 11 at 99,986,285 bp
  • C to A, chromosome 11 at 116,064,807 bp
  • T to C, chromosome 12 at 8,922,113 bp
  • A to C, chromosome 12 at 13,229,355 bp
  • G to T, chromosome 12 at 13,285,258 bp
  • T to C, chromosome 13 at 15,715,062 bp
  • T to C, chromosome 13 at 24,872,302 bp
  • G to A, chromosome 13 at 49,520,902 bp
  • G to T, chromosome 13 at 104,858,306 bp
  • A to T, chromosome 14 at 50,362,656 bp
  • G to A, chromosome 15 at 57,249,649 bp
  • G to T, chromosome 15 at 75,747,687 bp
  • G to A, chromosome 17 at 44,814,192 bp
  • A to G, chromosome 17 at 71,274,105 bp
  • A to T, chromosome 17 at 71,365,219 bp
  • A to G, chromosome 18 at 61,748,814 bp
  • A to T, chromosome 18 at 73,781,058 bp
  • G to A, chromosome 19 at 5,424,787 bp
  • T to C, chromosome 19 at 6,960,133 bp
  • T to C, chromosome 19 at 36,972,918 bp
  • A to G, chromosome 19 at 47,170,662 bp
  • T to A, chromosome 19 at 57,691,857 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7085 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045179-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.