Strain Name:
C57BL/6J-MtgxR7099Btlr/Mmmh
Stock Number:
045191-MU
Citation ID:
RRID:MMRRC_045191-MU
Other Names:
R7099 (G1)
Major Collection:

Strain Information

Scarb1
Name: scavenger receptor class B, member 1
Synonyms: Cla-1, SRBI, Chohd1, SR-BI, Srb1, Chohd1, Cd36l1, D5Ertd460e, Hlb398, Hdlq1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20778
HGNC: HGNC:1664
Homologene: 21132
Arid5b
Name: AT-rich interaction domain 5B
Synonyms: Mrf2alpha, 5430435G07Rik, Desrt, Mrf2, Mrf2beta
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71371
VEGA: 10
Homologene: 45872
Slc4a7
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 7
Synonyms: E430014N10Rik, NBC3, NBCn1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218756
VEGA: 14
Homologene: 2680
Lrrfip2
Name: leucine rich repeat (in FLII) interacting protein 2
Synonyms: 5133400F20Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71268
HGNC: HGNC:6703
Homologene: 22476
Nf1
Name: neurofibromin 1
Synonyms: neurofibromin, Mhdadsk9, Dsk9, Nf-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Brpf3
Name: bromodomain and PHD finger containing, 3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268936
Homologene: 16092
Acly
Name: ATP citrate lyase
Synonyms: A730098H14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 104112
HGNC: HGNC:115
Homologene: 854
Trappc9
Name: trafficking protein particle complex 9
Synonyms: 4632408O18Rik, TRS130, Nibp, 1810044A24Rik, 2900005P22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 76510
VEGA: 15
Homologene: 81931
Cobl
Name: cordon-bleu WH2 repeat
Synonyms: C530045F18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12808
Homologene: 9058
Sdad1
Name: SDA1 domain containing 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231452
Homologene: 6036
Stag1
Name: STAG1 cohesin complex component
Synonyms: Scc3, SA-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20842
Homologene: 21191
Pias1
Name: protein inhibitor of activated STAT 1
Synonyms: GBP, 2900068C24Rik, Ddxbp1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56469
VEGA: 9
HGNC: HGNC:2752
Homologene: 22953
Tep1
Name: telomerase associated protein 1
Synonyms: Tp1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21745
VEGA: 14
Homologene: 5157
Zzef1
Name: zinc finger, ZZ-type with EF hand domain 1
Synonyms: 8430405D05Rik, C130099L13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 195018
Homologene: 9027
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: SYNE-1, A330049M09Rik, enaptin165, nesprin-1, C130039F11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Nuf2
Name: NUF2, NDC80 kinetochore complex component
Synonyms: Cdca1, 2410003C07Rik, Nuf2R
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66977
Homologene: 40205
Nr5a1
Name: nuclear receptor subfamily 5, group A, member 1
Synonyms: Ftzf1, adrenal 4-binding protein, Ftz-F1, steroidogenic factor 1, SF-1, ELP, Ad4BP, SF1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26423
HGNC: HGNC:7983
Homologene: 3638
Flii
Name: flightless I actin binding protein
Synonyms: 3632430F08Rik, Fliih
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14248
HGNC: HGNC:3750
Homologene: 11092
C3
Name: complement component 3
Synonyms: Plp, acylation stimulating protein, complement factor 3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12266
HGNC: HGNC:1318
Homologene: 68031
Nbeal2
Name: neurobeachin-like 2
Synonyms: 1110014F23Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235627
Homologene: 86422
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, Dnahc8, P1-Loop
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Usp42
Name: ubiquitin specific peptidase 42
Synonyms: D5Ertd591e, 2410140K03Rik, A630018G05Rik, 3110031A07Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76800
Homologene: 35425
Prom2
Name: prominin 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 192212
Homologene: 44536
Dennd1c
Name: DENN domain containing 1C
Synonyms: 4432409M07Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 70785
VEGA: 17
Homologene: 11773
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
Sdk2
Name: sidekick cell adhesion molecule 2
Synonyms: 4632412F08Rik, 5330435L01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237979
Homologene: 10406
Nav3
Name: neuron navigator 3
Synonyms: Pomfil1p, steerin 3, unc53H3, 9630020C08Rik, 4732483H20Rik, POMFIL1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 260315
Homologene: 56688
Mgam
Name: maltase-glucoamylase
Synonyms: 6030407P20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232714
HGNC: HGNC:7043
Homologene: 130099
Or4k51
Name: olfactory receptor family 4 subfamily K member 51
Synonyms: GA_x6K02T2Q125-72805651-72806589, MOR248-5, Olfr1301
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258889
Homologene: 74057
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Slc45a1
Name: solute carrier family 45, member 1
Synonyms: Dnb5
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242773
Homologene: 44908
Vmn1r73
Name: vomeronasal 1 receptor 73
Synonyms: V1rg2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 171237
Homologene: 103842
Zfp804b
Name: zinc finger protein 804B
Synonyms: LOC207618
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 207618
Homologene: 52304
Otud7a
Name: OTU domain containing 7A
Synonyms: Cezanne 2 protein, Otud7
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 170711
Homologene: 15642
Tcaf2
Name: TRPM8 channel-associated factor 2
Synonyms: Fam115c
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232748
Homologene: 17147
Tigd2
Name: tigger transposable element derived 2
Synonyms: 3632410O17Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68140
Homologene: 129603
Ankar
Name: ankyrin and armadillo repeat containing
Synonyms: 4932422E22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 319695
Homologene: 85163
Zfp352
Name: zinc finger protein 352
Synonyms: 2czf48
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 236537
Homologene: 45160
Tbc1d9
Name: TBC1 domain family, member 9
Synonyms: C76116, 4933431N12Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71310
Homologene: 57079
Or8g33
Name: olfactory receptor family 8 subfamily G member 33
Synonyms: GA_x6K02T2PVTD-33124064-33123120, Olfr952, MOR171-21
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235248
VEGA: 9
Homologene: 133698
Zfp595
Name: zinc finger protein 595
Synonyms: A230042K10Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218314
Homologene: 120258
Ugt2b37
Name: UDP glucuronosyltransferase 2 family, polypeptide B37
Synonyms: 0610033E06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 112417
Homologene: 137225
Megf8
Name: multiple EGF-like-domains 8
Synonyms: m687Ddg, b2b288Clo, b2b1702Clo, Egfl4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269878
HGNC: HGNC:3233
Homologene: 15988
Map1a
Name: microtubule-associated protein 1 A
Synonyms: Mtap1, Mtap1a, Mtap-1, 6330416M19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17754
HGNC: HGNC:6835
Homologene: 1778
Kdr
Name: kinase insert domain protein receptor
Synonyms: Flk1, VEGFR2, Flk-1, VEGFR-2, vascular endothelial growth factor receptor- 2, orv, VEGF receptor-2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16542
HGNC: HGNC:6307
Homologene: 55639
Spata22
Name: spermatogenesis associated 22
Synonyms: LOC380709
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380709
Homologene: 13076
Adgrf1
Name: adhesion G protein-coupled receptor F1
Synonyms: 5031409J19Rik, Gpr110
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 77596
Homologene: 124643
Otulin
Name: OTU deubiquitinase with linear linkage specificity
Synonyms: Fam105b, m7-1Sapc, gumby, m3Sapc
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 432940
VEGA: 15
Homologene: 106591
Sidt1
Name: SID1 transmembrane family, member 1
Synonyms: B830021E24Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 320007
Homologene: 41189
Adam29
Name: a disintegrin and metallopeptidase domain 29
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244486
HGNC: HGNC:207
Homologene: 8607
Lmx1a
Name: LIM homeobox transcription factor 1 alpha
Synonyms: Lmx1.1, shaker short-tail
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 110648
HGNC: HGNC:6653
Homologene: 24921
Fhod3
Name: formin homology 2 domain containing 3
Synonyms: A930009H06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225288
VEGA: 18
Homologene: 45323
Catsperd
Name: cation channel sperm associated auxiliary subunit delta
Synonyms: 4921529N20Rik, 4933402B14Rik, Tmem146, Gm6095
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106757
VEGA: 17
Homologene: 51896
Neu3
Name: neuraminidase 3
Synonyms: membrane sialidase, ganglioside sialidase
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 50877
HGNC: HGNC:7760
Homologene: 4847
Cryzl2
Name: crystallin zeta like 2
Synonyms: BC026585, quinone reductase-like 2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226527
Homologene: 41713
Gramd2b
Name: GRAM domain containing 2B
Synonyms: 9130427A09Rik, 9030613F08Rik, Gramd3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 107022
VEGA: 18
Homologene: 32570
Usp44
Name: ubiquitin specific peptidase 44
Synonyms: E430004F17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 327799
VEGA: 10
Homologene: 12961
Calr4
Name: calreticulin 4
Synonyms: 4933403L16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 108802
Homologene: 86813
4930453N24Rik
Name: RIKEN cDNA 4930453N24 gene
Synonyms: din
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67609
Homologene: 27867
Ndst1
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
Synonyms: Hsst, Ndst-1, 1200015G06Rik, glucosaminyl N-deacetylase/N-sulfotransferase 1, b2b2230Clo
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 15531
VEGA: 18
HGNC: HGNC:7680
Homologene: 20386
Or4d10c
Name: olfactory receptor family 4 subfamily D member 10C
Synonyms: Olfr1426, GA_x6K02T2RE5P-2447610-2446675, MOR239-1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258805
Homologene: 128079
Errfi1
Name: ERBB receptor feedback inhibitor 1
Synonyms: 1300002F13Rik, Mig-6, RALT
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74155
Homologene: 10344
Or6d12
Name: olfactory receptor family 6 subfamily D member 12
Synonyms: GA_x54KRFPKN04-58149882-58150865, MOR119-4, Olfr212, 4931403F16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258019
Homologene: 74186
Fxyd1
Name: FXYD domain-containing ion transport regulator 1
Synonyms: PML, 0610012C17Rik, 1110006M24Rik, phospholemman, PLM
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56188
HGNC: HGNC:4025
Homologene: 3691
Gdi1
Name: GDP dissociation inhibitor 1
Synonyms: GDIA, Rab GDIalpha
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 14567
HGNC: HGNC:4226
Homologene: 37487
Vmn2r34
Name: vomeronasal 2, receptor 34
Synonyms: ENSMUSG00000070841
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100042636
Homologene: 113703
Fbxw27
Name: F-box and WD-40 domain protein 27
Synonyms: 1700124P09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76998
Homologene: 110776
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 72,643,293 bp
  • G to A, chromosome 1 at 157,488,584 bp
  • G to A, chromosome 1 at 167,830,546 bp
  • G to A, chromosome 1 at 169,506,072 bp
  • G to T, chromosome 2 at 38,694,136 bp
  • C to A, chromosome 2 at 82,987,624 bp
  • A to T, chromosome 2 at 111,755,076 bp
  • T to A, chromosome 2 at 121,300,517 bp
  • T to C, chromosome 2 at 127,539,778 bp
  • A to G, chromosome 4 at 90,224,880 bp
  • A to T, chromosome 4 at 109,242,229 bp
  • A to T, chromosome 4 at 150,629,573 bp
  • T to C, chromosome 4 at 150,866,768 bp
  • A to T, chromosome 5 at 6,772,161 bp
  • A to G, chromosome 5 at 75,944,333 bp
  • A to G, chromosome 5 at 87,240,989 bp
  • A to G, chromosome 5 at 92,293,973 bp
  • A to T, chromosome 5 at 125,304,350 bp
  • A to T, chromosome 5 at 143,726,645 bp
  • T to C, chromosome 6 at 40,661,716 bp
  • C to T, chromosome 6 at 42,630,341 bp
  • C to A, chromosome 6 at 59,210,181 bp
  • T to A, chromosome 6 at 116,516,760 bp
  • A to T, chromosome 7 at 7,672,541 bp
  • T to C, chromosome 7 at 11,756,393 bp
  • A to T, chromosome 7 at 25,346,520 bp
  • T to G, chromosome 7 at 31,053,033 bp
  • A to G, chromosome 7 at 63,757,455 bp
  • G to A, chromosome 7 at 99,813,820 bp
  • AGGCGCAGAAACCCTGGC to AGGC, chromosome 7 at 141,634,450 bp
  • A to C, chromosome 8 at 55,871,404 bp
  • A to G, chromosome 8 at 83,254,891 bp
  • G to A, chromosome 9 at 39,426,303 bp
  • A to G, chromosome 9 at 62,881,145 bp
  • G to A, chromosome 9 at 100,944,826 bp
  • G to T, chromosome 9 at 109,770,155 bp
  • A to T, chromosome 9 at 110,645,438 bp
  • A to G, chromosome 9 at 111,173,108 bp
  • T to C, chromosome 10 at 5,123,744 bp
  • T to C, chromosome 10 at 68,098,179 bp
  • T to C, chromosome 10 at 93,850,187 bp
  • T to C, chromosome 10 at 109,703,334 bp
  • T to A, chromosome 11 at 12,296,540 bp
  • A to G, chromosome 11 at 60,720,655 bp
  • T to C, chromosome 11 at 72,872,649 bp
  • T to C, chromosome 11 at 73,340,399 bp
  • T to C, chromosome 11 at 79,570,330 bp
  • T to C, chromosome 11 at 100,492,291 bp
  • T to C, chromosome 11 at 113,834,905 bp
  • T to A, chromosome 13 at 67,317,647 bp
  • T to A, chromosome 14 at 14,733,750 bp
  • T to C, chromosome 14 at 50,844,487 bp
  • A to G, chromosome 15 at 27,608,746 bp
  • A to G, chromosome 15 at 72,693,619 bp
  • A to G, chromosome 16 at 44,243,497 bp
  • C to T, chromosome 16 at 64,770,788 bp
  • T to C, chromosome 17 at 28,806,637 bp
  • A to T, chromosome 17 at 30,704,724 bp
  • T to C, chromosome 17 at 43,310,602 bp
  • T to G, chromosome 17 at 56,628,811 bp
  • A to G, chromosome 17 at 57,067,915 bp
  • T to C, chromosome 17 at 57,206,276 bp
  • A to G, chromosome 18 at 25,090,162 bp
  • C to T, chromosome 18 at 56,491,945 bp
  • A to G, chromosome 18 at 60,695,500 bp
  • A to G, chromosome 19 at 12,088,166 bp
  • G to A, chromosome X at 74,306,855 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7099 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045191-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.