Strain Name:
C57BL/6J-MtgxR7108Btlr/Mmmh
Stock Number:
045200-MU
Citation ID:
RRID:MMRRC_045200-MU
Other Names:
R7108 (G1)
Major Collection:

Strain Information

Myo5a
Name: myosin VA
Synonyms: MVa, MyoVA, Myo5, flail, 9630007J19Rik, Dbv
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17918
HGNC: HGNC:7602
Homologene: 20100
Acadm
Name: acyl-Coenzyme A dehydrogenase, medium chain
Synonyms: MCAD
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11364
HGNC: HGNC:89
Homologene: 3
Frem2
Name: Fras1 related extracellular matrix protein 2
Synonyms: 8430406N05Rik, 6030440P17Rik, my, ne, b2b1562Clo
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242022
Homologene: 18454
Dpagt1
Name: dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
Synonyms: GPT, Dpagt2, Gnpta
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13478
VEGA: 9
HGNC: HGNC:2995
Homologene: 1058
Irf1
Name: interferon regulatory factor 1
Synonyms: Irf-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16362
HGNC: HGNC:6116
Homologene: 1658
Arfgef2
Name: ADP ribosylation factor guanine nucleotide exchange factor 2
Synonyms: BIG2, E230011G24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99371
Homologene: 111880
Tns3
Name: tensin 3
Synonyms: TEM6, F830010I22Rik, Tens1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 319939
Homologene: 49713
Shmt1
Name: serine hydroxymethyltransferase 1 (soluble)
Synonyms: mshmt2, mshmt1, mshmt, Shmt
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20425
Homologene: 3074
Scn8a
Name: sodium channel, voltage-gated, type VIII, alpha
Synonyms: med, seal, motor end-plate disease, nmf2, ataxia 3, mnd2, mnd-2, C630029C19Rik, nmf58, NaCh6, Nav1.6, nmf335, NMF335, nur14
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20273
Homologene: 7927
Ireb2
Name: iron responsive element binding protein 2
Synonyms: Irp2, D9Ertd85e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 64602
VEGA: 9
HGNC: HGNC:6115
Homologene: 11280
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, C130061D10Rik, Phr1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105689
Homologene: 9005
Brpf3
Name: bromodomain and PHD finger containing, 3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268936
Homologene: 16092
Fry
Name: FRY microtubule binding protein
Synonyms: cg003, 9330186A19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320365
Homologene: 113770
Ralgapb
Name: Ral GTPase activating protein, beta subunit (non-catalytic)
Synonyms: B230339M05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228850
Homologene: 10666
Cyth1
Name: cytohesin 1
Synonyms: CLM1, CTH-1, Pscd1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19157
HGNC: HGNC:9501
Homologene: 31262
Malt1
Name: MALT1 paracaspase
Synonyms: D430033E09Rik, paracaspase, Pcasp1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240354
HGNC: HGNC:6819
Homologene: 4938
Atp6v1b2
Name: ATPase, H+ transporting, lysosomal V1 subunit B2
Synonyms: HO57, Atp6b2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11966
HGNC: HGNC:854
Homologene: 1279
Adra2c
Name: adrenergic receptor, alpha 2c
Synonyms: alpha2-C4, subtype alpha2-C4, [a]2C, alpha2C, Adra-2c
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11553
HGNC: HGNC:283
Homologene: 20170
Ddi2
Name: DNA-damage inducible protein 2
Synonyms: 9130022E05Rik, 1110056G13Rik, 1700027M01Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68817
Homologene: 121661
Ankrd10
Name: ankyrin repeat domain 10
Synonyms: 4833425P12Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102334
Homologene: 9768
Gprc5c
Name: G protein-coupled receptor, family C, group 5, member C
Synonyms: 1110028I06Rik, 3200002M13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70355
Homologene: 11099
Lca5
Name: Leber congenital amaurosis 5 (human)
Synonyms: 5730406O13Rik, ORF64, 4930431B11Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 75782
Homologene: 32718
2810021J22Rik
Name: RIKEN cDNA 2810021J22 gene
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69944
Homologene: 138400
Muc16
Name: mucin 16
Synonyms: LOC385009, 1110008I14Rik, Gm21044
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73732
Homologene: 141193
Cox6b1
Name: cytochrome c oxidase, subunit 6B1
Synonyms: 2010000G05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 110323
HGNC: HGNC:2280
Homologene: 39658
E4f1
Name: E4F transcription factor 1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13560
VEGA: 17
HGNC: HGNC:3121
Homologene: 3259
Bloc1s1
Name: biogenesis of lysosomal organelles complex-1, subunit 1
Synonyms: Gcn5l1, BLOS1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14533
HGNC: HGNC:4200
Homologene: 1140
Dsg2
Name: desmoglein 2
Synonyms: D18Ertd293e
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13511
HGNC: HGNC:3049
Homologene: 1464
Ube2f
Name: ubiquitin-conjugating enzyme E2F (putative)
Synonyms: 2510010F15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67921
Homologene: 12212
Slmap
Name: sarcolemma associated protein
Synonyms: Slap, D330001L02Rik, Miranda
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 83997
Homologene: 31428
Ssh2
Name: slingshot protein phosphatase 2
Synonyms: SSH-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237860
Homologene: 14116
Hps6
Name: HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
Synonyms: 5330434M19Rik, ruby eye, ru, BLOC-2, Hermansky-Pudlak syndrome 6
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20170
VEGA: 19
Homologene: 11691
Tek
Name: TEK receptor tyrosine kinase
Synonyms: Hyk, Tie2, Cd202b, tie-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21687
Homologene: 397
Cfi
Name: complement component factor i
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12630
HGNC: HGNC:5394
Homologene: 171
Sall3
Name: spalt like transcription factor 3
Synonyms: Msal, Msal-1, Spalt, Salt, B130022O04Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 20689
VEGA: 18
Homologene: 18142
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Hdhc3, HL-19, DLP12, HL19, DHC3, LOC380889, 4921531P07Rik, Dnahc7l, Dnahc12
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Ndst4
Name: N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
Synonyms: 4930439H17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 64580
Homologene: 11208
Mrc1
Name: mannose receptor, C type 1
Synonyms: CD206, MR
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17533
HGNC: HGNC:7228
Homologene: 37622
Dnai7
Name: dynein axonemal intermediate chain 7
Synonyms: A230084G12Rik, Las1, Casc1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320662
Homologene: 41242
Drc3
Name: dynein regulatory complex subunit 3
Synonyms: 4930449E07Rik, Lrrc48, m6Bei
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74665
Homologene: 12581
Hc
Name: hemolytic complement
Synonyms: C5a, C5, He, Hfib2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Nxnl1
Name: nucleoredoxin-like 1
Synonyms: RdCVF, A930031O08Rik, Txnl6
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234404
Homologene: 89165
Fscn1
Name: fascin actin-bundling protein 1
Synonyms: Fan1, fascin-1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14086
Homologene: 48164
Nlrp9b
Name: NLR family, pyrin domain containing 9B
Synonyms: Nalp9b, Nalp-delta
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243874
Homologene: 18530
Eif2ak2
Name: eukaryotic translation initiation factor 2-alpha kinase 2
Synonyms: eIF-2 alpha, Pkr, dsRNA-activated kinase, IFN- type I-induced and dsRNA-activated kinase, IFN-induced and double-stranded RNA-activated kinase, Prkr, Tik, eIF-2 alpha, 4732414G15Rik, 2310047A08Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19106
HGNC: HGNC:9437
Homologene: 48134
Tubd1
Name: tubulin, delta 1
Synonyms: 4930550G19Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56427
Homologene: 9443
Golgb1
Name: golgin B1
Synonyms: Giantin, C130074L01Rik, F730017E11Rik, 6330407A06Rik, Gm6840
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224139
HGNC: HGNC:4429
Homologene: 68401
Stard7
Name: StAR related lipid transfer domain containing 7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99138
Homologene: 32463
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50720
Or52b4i
Name: olfactory receptor family 52 subfamily B member 4I
Synonyms: GA_x6K02T2PBJ9-5263046-5263989, MOR31-13, Olfr548
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258229
4930503L19Rik
Name: RIKEN cDNA 4930503L19 gene
Synonyms: Las2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 269033
Homologene: 52120
Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Synonyms: Cav2.3, Cchra1, alpha1E
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12290
HGNC: HGNC:1392
Homologene: 20185
Daam2
Name: dishevelled associated activator of morphogenesis 2
Synonyms: 2310016D11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 76441
VEGA: 17
Homologene: 69186
Or2ag12
Name: olfactory receptor family 2 subfamily AG member 12
Synonyms: GA_x6K02T2PBJ9-9055944-9054994, MOR283-8, Olfr693
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258445
Cyp3a59
Name: cytochrome P450, family 3, subfamily a, polypeptide 59
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100041449
Homologene: 135775
Lrrc17
Name: leucine rich repeat containing 17
Synonyms: 6130400C22Rik, 4833425M04Rik, 37kDa
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74511
Homologene: 55929
Cilp2
Name: cartilage intermediate layer protein 2
Synonyms: CLIP-2, 1110031K21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 68709
Homologene: 17713
Ccdc186
Name: coiled-coil domain containing 186
Synonyms: Otg1, 1810028B20Rik, A630007B06Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 213993
Homologene: 9963
Krt12
Name: keratin 12
Synonyms: K12, Krt1-12
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268482
HGNC: HGNC:6414
Homologene: 188
Prkcz
Name: protein kinase C, zeta
Synonyms: Pkcz, zetaPKC, aPKCzeta
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18762
HGNC: HGNC:9412
Homologene: 55681
Vmn2r109
Name: vomeronasal 2, receptor 109
Synonyms: EG627814
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627814
Homologene: 129678
Odr4
Name: odr4 GPCR localization factor homolog
Synonyms: 1810053E15Rik, BC003331
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226499
Homologene: 41202
Kif12
Name: kinesin family member 12
Synonyms: N-9 kinesin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16552
Homologene: 7796
Or2t49
Name: olfactory receptor family 2 subfamily T member 49
Synonyms: GA_x6K02T2NKPP-912840-913784, MOR275-4, Olfr331
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 100502887
Homologene: 133015
Abcd2
Name: ATP-binding cassette, sub-family D member 2
Synonyms: ALDR, ALDL1, adrenoleukodystrophy related, ABC39
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 26874
VEGA: 15
HGNC: HGNC:66
Homologene: 55873
Cfap161
Name: cilia and flagella associated protein 161
Synonyms: 1700026D08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75556
Homologene: 12605
Man2b2
Name: mannosidase 2, alpha B2
Synonyms: 135 kDa alpha-D-mannosidase
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 17160
Homologene: 7411
Nat1
Name: N-acetyl transferase 1
Synonyms: Nat-1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17960
Homologene: 115468
Zfp764l1
Name: zinc finger protein 764 like 1
Synonyms: E430018J23Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101604
Homologene: 138471
Or1l4b
Name: olfactory receptor family 1 subfamily L member 4B
Synonyms: GA_x6K02T2NLDC-33831282-33832243, MOR138-4P, MOR138-7, Olfr364
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227794
HGNC: HGNC:8216
Pou5f2
Name: POU domain class 5, transcription factor 2
Synonyms: 1700013G10Rik, Sprm1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75507
Homologene: 83454
Or7a35
Name: olfactory receptor family 7 subfamily A member 35
Synonyms: GA_x6K02T2QGN0-2794907-2793948, MOR139-4, Olfr1351
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 259042
Homologene: 133668
Vmn2r39
Name: vomeronasal 2, receptor 39
Synonyms: EG545909
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 545909
Homologene: 113703
Hsd17b1
Name: hydroxysteroid (17-beta) dehydrogenase 1
Synonyms: 17beta-HSD, Hsd17ba
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15485
HGNC: HGNC:5210
Homologene: 37303
Gm16506
Name: predicted gene 16506
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 102634304
Homologene: 128452
Tfap2e
Name: transcription factor AP-2, epsilon
Synonyms: AP-2e, Tcfap2e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 332937
Homologene: 2422
Prr18
Name: proline rich 18
Synonyms: 9630019K15Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320111
VEGA: 17
Homologene: 52195
Gm21103
Name: predicted gene, 21103
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 118567363
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 91,265,219 bp
  • T to C, chromosome 1 at 150,382,290 bp
  • TTCCAGTCTC to TTC, chromosome 1 at 154,468,995 bp
  • C to T, chromosome 2 at 14,304,146 bp
  • G to T, chromosome 2 at 35,039,694 bp
  • C to T, chromosome 2 at 37,146,260 bp
  • A to G, chromosome 2 at 127,295,494 bp
  • T to C, chromosome 2 at 158,492,460 bp
  • A to T, chromosome 2 at 158,494,662 bp
  • T to A, chromosome 2 at 166,873,608 bp
  • T to C, chromosome 3 at 53,653,513 bp
  • A to G, chromosome 3 at 125,561,471 bp
  • G to A, chromosome 3 at 129,875,016 bp
  • A to T, chromosome 3 at 153,925,800 bp
  • A to T, chromosome 4 at 63,171,205 bp
  • A to T, chromosome 4 at 94,853,487 bp
  • A to G, chromosome 4 at 126,720,563 bp
  • A to T, chromosome 4 at 141,705,937 bp
  • G to A, chromosome 4 at 155,286,793 bp
  • T to C, chromosome 5 at 21,575,339 bp
  • A to G, chromosome 5 at 35,279,998 bp
  • C to T, chromosome 5 at 36,815,485 bp
  • T to C, chromosome 5 at 142,960,515 bp
  • A to T, chromosome 5 at 146,096,333 bp
  • T to C, chromosome 5 at 150,395,786 bp
  • T to A, chromosome 5 at 150,491,090 bp
  • G to A, chromosome 6 at 145,185,865 bp
  • T to C, chromosome 7 at 9,023,668 bp
  • A to T, chromosome 7 at 20,045,930 bp
  • A to G, chromosome 7 at 30,623,504 bp
  • A to T, chromosome 7 at 83,793,310 bp
  • A to T, chromosome 7 at 102,541,992 bp
  • G to A, chromosome 7 at 106,678,048 bp
  • A to G, chromosome 7 at 127,391,523 bp
  • AGGCGCAGAAACCCTGGC to AGGC, chromosome 7 at 141,634,450 bp
  • C to T, chromosome 8 at 11,612,624 bp
  • T to C, chromosome 8 at 67,491,020 bp
  • A to G, chromosome 8 at 69,102,501 bp
  • T to A, chromosome 8 at 69,881,129 bp
  • A to G, chromosome 8 at 71,566,554 bp
  • T to A, chromosome 9 at 18,655,233 bp
  • G to T, chromosome 9 at 44,327,021 bp
  • T to A, chromosome 9 at 54,906,641 bp
  • T to A, chromosome 9 at 75,129,992 bp
  • T to A, chromosome 9 at 83,423,169 bp
  • C to A, chromosome 10 at 79,017,649 bp
  • T to A, chromosome 10 at 128,922,723 bp
  • T to C, chromosome 11 at 8,437,251 bp
  • A to G, chromosome 11 at 53,774,412 bp
  • T to A, chromosome 11 at 58,502,554 bp
  • T to C, chromosome 11 at 58,880,924 bp
  • T to A, chromosome 11 at 60,370,554 bp
  • T to C, chromosome 11 at 60,798,644 bp
  • G to A, chromosome 11 at 77,454,794 bp
  • T to A, chromosome 11 at 86,557,805 bp
  • C to T, chromosome 11 at 99,416,052 bp
  • T to C, chromosome 11 at 101,079,209 bp
  • T to C, chromosome 11 at 114,864,282 bp
  • T to C, chromosome 11 at 118,182,913 bp
  • T to C, chromosome 13 at 78,025,265 bp
  • T to C, chromosome 14 at 6,303,774 bp
  • T to C, chromosome 14 at 26,422,521 bp
  • G to A, chromosome 14 at 26,778,912 bp
  • T to A, chromosome 14 at 43,724,302 bp
  • T to A, chromosome 14 at 61,211,009 bp
  • A to T, chromosome 14 at 103,122,603 bp
  • A to T, chromosome 15 at 91,191,274 bp
  • A to T, chromosome 15 at 101,039,778 bp
  • A to G, chromosome 16 at 36,913,721 bp
  • G to T, chromosome 17 at 8,341,531 bp
  • T to C, chromosome 17 at 20,564,744 bp
  • A to G, chromosome 17 at 24,444,578 bp
  • A to G, chromosome 17 at 28,817,125 bp
  • T to C, chromosome 17 at 49,460,674 bp
  • T to A, chromosome 17 at 78,858,536 bp
  • T to C, chromosome 18 at 20,601,863 bp
  • G to T, chromosome 18 at 65,464,051 bp
  • A to T, chromosome 18 at 70,468,476 bp
  • G to A, chromosome 18 at 80,973,754 bp
  • T to A, chromosome 19 at 46,005,490 bp
  • T to C, chromosome 19 at 56,798,760 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7108 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045200-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.