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Strain Name:
C57BL/6J-MtgxR7257Btlr/Mmmh
Stock Number:
045318-MU
Citation ID:
RRID:MMRRC_045318-MU
Other Names:
R7257 (G1)
Major Collection:

Strain Information

Phb1
Name: prohibitin 1
Synonyms: Phb
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18673
HGNC: HGNC:8912
Homologene: 1980
Myh7
Name: myosin, heavy polypeptide 7, cardiac muscle, beta
Synonyms: Myhc-b, Myhcb, beta-MHC, B-MHC, MYH-beta/slow, MyHC-I, betaMHC
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 140781
HGNC: HGNC:7577
Homologene: 68044
Septin3
Name: septin 3
Synonyms: Sep3, B530002E20Rik, 3110018K01Rik, Sept3, Gm46500
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 24050
VEGA: 15
Homologene: 99740
Ptch1
Name: patched 1
Synonyms: Ptc, Patched 1, Ptc1, A230106A15Rik, wig
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 19206
HGNC: HGNC:9585
Homologene: 223
Adk
Name: adenosine kinase
Synonyms: AK, 5033405D03Rik, 2310026J05Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 11534
VEGA: 14
HGNC: HGNC:257
Homologene: 4891
Rapgef2
Name: Rap guanine nucleotide exchange factor (GEF) 2
Synonyms: 5830453M24Rik, Pdzgef1, RA-GEF-1, CNRasGEF, nRapGEP
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76089
Homologene: 35477
Ddx55
Name: DEAD box helicase 55
Synonyms: 2810021H22Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67848
Homologene: 12196
Brd2
Name: bromodomain containing 2
Synonyms: Ring3, Frg-1, D17H6S113E, Fsrg1, Rnf3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14312
HGNC: HGNC:1103
Homologene: 74540
Atxn2
Name: ataxin 2
Synonyms: ATX2, 9630045M23Rik, Sca2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20239
Homologene: 2234
Pole2
Name: polymerase (DNA directed), epsilon 2 (p59 subunit)
Synonyms: DNA polymerase epsilon small subunit
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18974
VEGA: 12
HGNC: HGNC:9178
Homologene: 2015
Sltm
Name: SAFB-like, transcription modulator
Synonyms: 5730455C01Rik, 9130215G10Rik, 5730555F13Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66660
VEGA: 9
Homologene: 11696
Tirap
Name: toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
Synonyms: wyatt, MyD88-adapter-like, Mal, C130027E04Rik, Mal
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 117149
Homologene: 14285
Rnf123
Name: ring finger protein 123
Synonyms: KPC1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 84585
Homologene: 11112
Trim66
Name: tripartite motif-containing 66
Synonyms: D7H11orf29, Tif1d
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330627
Homologene: 28044
Rassf3
Name: Ras association (RalGDS/AF-6) domain family member 3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 192678
VEGA: 10
Homologene: 16365
Mmp17
Name: matrix metallopeptidase 17
Synonyms: MT4-MMP, membrane type-4 matrix metalloproteinase
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 23948
HGNC: HGNC:7163
Homologene: 22669
Grm7
Name: glutamate receptor, metabotropic 7
Synonyms: mGluR7, Gpr1g, E130018M02Rik, 6330570A01Rik, mGlu7a receptor
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 108073
HGNC: HGNC:4599
Homologene: 20233
Dock7
Name: dedicator of cytokinesis 7
Synonyms: 3110056M06Rik, LOC242555, m
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67299
Homologene: 23566
Cbln2
Name: cerebellin 2 precursor protein
Synonyms: 6330593N19Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12405
HGNC: HGNC:1544
Homologene: 18203
Pfas
Name: phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
Synonyms: 4432409B16Rik, Sofa
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237823
HGNC: HGNC:8863
Homologene: 5970
Dhx32
Name: DEAH-box helicase 32 (putative)
Synonyms: Ddx32, DEAH (Asp-Glu-Ala-His) box polypeptide 32
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101437
Homologene: 56798
Ighmbp2
Name: immunoglobulin mu DNA binding protein 2
Synonyms: Catf1, AEP, sma, Smbp2, Smubp2, p110 subunit, RIPE3b1, Smbp-2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20589
HGNC: HGNC:5542
Homologene: 1642
Atp5po
Name: ATP synthase peripheral stalk subunit OSCP
Synonyms: D12Wsu28e, Atp5o
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 28080
HGNC: HGNC:850
Homologene: 1283
Dync1i2
Name: dynein cytoplasmic 1 intermediate chain 2
Synonyms: 3110079H08Rik, Dncic2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13427
HGNC: HGNC:2964
Homologene: 37921
Fbxo34
Name: F-box protein 34
Synonyms: 5830426G16Rik, 2900057B08Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 78938
VEGA: 14
Homologene: 12713
Itpr3
Name: inositol 1,4,5-triphosphate receptor 3
Synonyms: Itpr-3, Ip3r3, tf
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16440
HGNC: HGNC:6182
Homologene: 1675
Dock8
Name: dedicator of cytokinesis 8
Synonyms: 1200017A24Rik, 5830472H07Rik, A130095G14Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 76088
VEGA: 19
Homologene: 52414
Mns1
Name: meiosis-specific nuclear structural protein 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17427
Homologene: 40628
Oca2
Name: oculocutaneous albinism II
Synonyms: D7H15S12, D7H15S12, p
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18431
HGNC: HGNC:8101
Homologene: 37281
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244484
Homologene: 12460
Myh2
Name: myosin, heavy polypeptide 2, skeletal muscle, adult
Synonyms: MyHC-IIa, MHC2A, Myhs-f, Myhs-f1, Myhsf1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17882
HGNC: HGNC:7572
Homologene: 23019
Camk2g
Name: calcium/calmodulin-dependent protein kinase II gamma
Synonyms: CaMK II, Ca2+/calmodulin-dependent protein kinase II, Camkg, 5930429P18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12325
VEGA: 14
HGNC: HGNC:1463
Homologene: 15596
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 81877
Homologene: 49589
Pitpnm2
Name: phosphatidylinositol transfer protein, membrane-associated 2
Synonyms: RDGBA2, NIR3, Rdgb2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19679
Homologene: 7915
Phlpp2
Name: PH domain and leucine rich repeat protein phosphatase 2
Synonyms: C130044A18Rik, Phlppl
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244650
Homologene: 71015
Dglucy
Name: D-glutamate cyclase
Synonyms: 9030617O03Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217830
Homologene: 11798
Pla2r1
Name: phospholipase A2 receptor 1
Synonyms: PLA2-I receptor, M-type receptor, Pla2g1br
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18779
HGNC: HGNC:9042
Homologene: 32016
Pip5kl1
Name: phosphatidylinositol-4-phosphate 5-kinase-like 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227733
Homologene: 45457
Mymk
Name: myomaker, myoblast fusion factor
Synonyms: 1110002H13Rik, Tmem8c
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66139
Homologene: 11925
Pla2g4c
Name: phospholipase A2, group IVC (cytosolic, calcium-independent)
Synonyms: CPLA2-gamma
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232889
HGNC: HGNC:9037
Homologene: 115256
Smarca2
Name: SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2
Synonyms: brm, Snf2l2, 2610209L14Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 67155
Homologene: 2308
Mog
Name: myelin oligodendrocyte glycoprotein
Synonyms: B230317G11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17441
HGNC: HGNC:7197
Homologene: 111009
Or5d16
Name: olfactory receptor family 5 subfamily D member 16
Synonyms: GA_x6K02T2Q125-49426894-49425950, MOR174-10, Olfr1155
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258636
Homologene: 133739
Zbtb37
Name: zinc finger and BTB domain containing 37
Synonyms: D430004I08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240869
Homologene: 13048
Acot11
Name: acyl-CoA thioesterase 11
Synonyms: BFIT1, 2010309H15Rik, Them1, 1110020M10Rik, Thea
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329910
Homologene: 11977
Efcab5
Name: EF-hand calcium binding domain 5
Synonyms: 4930563A03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 319634
Homologene: 63366
Or14c39
Name: olfactory receptor family 14 subfamily C member 39
Synonyms: GA_x6K02T2NHDJ-9425121-9424195, MOR220-2, Olfr292
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258613
Homologene: 115526
Or6c8b
Name: olfactory receptor family 6 subfamily C member 8B
Synonyms: GA_x6K02T2PULF-10732607-10731678, MOR115-4, Olfr765
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 544748
Homologene: 105186
Veph1
Name: ventricular zone expressed PH domain-containing 1
Synonyms: Veph, 2810471M23Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72789
Homologene: 11624
Abtb1
Name: ankyrin repeat and BTB domain containing 1
Synonyms: BPOZ, EF1ABP
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 80283
Homologene: 32731
Dmac2l
Name: distal membrane arm assembly component 2 like
Synonyms: facyor B, 1110015E18Rik, Atp5s
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68055
VEGA: 12
Homologene: 12232
Flt4
Name: FMS-like tyrosine kinase 4
Synonyms: VEGFR3, VEGFR-3, Flt-4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14257
HGNC: HGNC:3767
Homologene: 7321
Fam83g
Name: family with sequence similarity 83, member G
Synonyms: 2310040C09Rik, wly
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69640
Homologene: 85169
Ovch2
Name: ovochymase 2
Synonyms: 9230106D23Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244199
Homologene: 18255
Or6c69
Name: olfactory receptor family 6 subfamily C member 69
Synonyms: GA_x6K02T2PULF-11590830-11589892, MOR113-1, Olfr816
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258667
Homologene: 133584
Tlr5
Name: toll-like receptor 5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 53791
Homologene: 20698
Akr1c14
Name: aldo-keto reductase family 1, member C14
Synonyms: 9030611N15Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105387
Homologene: 138093
Tmcc1
Name: transmembrane and coiled coil domains 1
Synonyms: 3632431M01Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330401
Homologene: 8995
Amh
Name: anti-Mullerian hormone
Synonyms: MIS, Mullerian inhibiting substance
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11705
VEGA: 10
HGNC: HGNC:464
Homologene: 68060
Padi1
Name: peptidyl arginine deiminase, type I
Synonyms: Pdi1, Pad type 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18599
Homologene: 7881
Ncoa4
Name: nuclear receptor coactivator 4
Synonyms: 4432406M01Rik, 1110034E15Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 27057
HGNC: HGNC:7671
Homologene: 38052
Antxrl
Name: anthrax toxin receptor-like
Synonyms: 1700112N15Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239029
VEGA: 14
Homologene: 52111
B3gat3
Name: beta-1,3-glucuronyltransferase 3
Synonyms: 2810405M13Rik, GlcAT-I
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72727
VEGA: 19
HGNC: HGNC:923
Homologene: 56554
Rnf138
Name: ring finger protein 138
Synonyms: Trif-d, 2810480D20Rik, 2410015A17Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 56515
VEGA: 18
Homologene: 9446
Itga7
Name: integrin alpha 7
Synonyms: [a]7, alpha7
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16404
VEGA: 10
HGNC: HGNC:6143
Homologene: 37592
Or51f1d
Name: olfactory receptor family 51 subfamily F member 1D
Synonyms: GA_x6K02T2PBJ9-5762668-5763618, MOR14-6, Olfr583
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258752
Homologene: 133721
Cry2
Name: cryptochrome circadian regulator 2
Synonyms: D130054K12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12953
HGNC: HGNC:2385
Homologene: 56466
Tcl1b1
Name: T cell leukemia/lymphoma 1B, 1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 27379
VEGA: 12
Homologene: 83274
Slc35a4
Name: solute carrier family 35, member A4
Synonyms: 2610030J16Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67843
Homologene: 12195
Gpr150
Name: G protein-coupled receptor 150
Synonyms: PGR11, C030001A19Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238725
Homologene: 18457
Fxyd5
Name: FXYD domain-containing ion transport regulator 5
Synonyms: EF-8, Oit2, dysadherin
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18301
HGNC: HGNC:4029
Homologene: 7458
Odam
Name: odontogenic, ameloblast asssociated
Synonyms: 2310011G06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69592
Homologene: 49511
Or2w1
Name: olfactory receptor family 2 subfamily W member 1
Synonyms: IA3, GA_x6K02T2N5E5-9379-8514, MOR256-31, GA_x6K02T2QHY8-12114828-12113875, MOR256-37P, MOR256-61, Olfr42, Olfr263-ps1, Olfr263
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 18341
HGNC: HGNC:8281
Homologene: 12791
Vmn1r125
Name: vomeronasal 1 receptor 125
Synonyms: Gm8519
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 667215
Homologene: 104166
Pcdhga4
Name: protocadherin gamma subfamily A, 4
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93712
HGNC: HGNC:8702
Homologene: 81866
AL732309.1
Name:
Type: Gene
Species: Mouse
Chromosome: 2
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 161,032,661 bp
  • T to A, chromosome 1 at 182,974,233 bp
  • A to T, chromosome 2 at 25,245,839 bp
  • A to T, chromosome 2 at 27,067,368 bp
  • T to C, chromosome 2 at 32,580,431 bp
  • A to T, chromosome 2 at 60,427,625 bp
  • T to A, chromosome 2 at 71,249,356 bp
  • A to G, chromosome 2 at 76,741,094 bp
  • A to G, chromosome 2 at 87,943,571 bp
  • A to T, chromosome 2 at 92,412,981 bp
  • A to G, chromosome 3 at 27,138,535 bp
  • C to A, chromosome 3 at 66,158,282 bp
  • A to T, chromosome 3 at 79,082,627 bp
  • T to A, chromosome 4 at 98,973,412 bp
  • G to A, chromosome 4 at 106,758,402 bp
  • C to A, chromosome 4 at 140,829,471 bp
  • A to C, chromosome 5 at 87,887,545 bp
  • T to G, chromosome 5 at 121,785,817 bp
  • T to A, chromosome 5 at 124,125,356 bp
  • T to A, chromosome 5 at 124,560,721 bp
  • C to A, chromosome 5 at 129,595,633 bp
  • A to T, chromosome 6 at 88,839,452 bp
  • A to G, chromosome 6 at 110,646,118 bp
  • A to G, chromosome 6 at 116,107,338 bp
  • G to A, chromosome 7 at 13,325,744 bp
  • A to T, chromosome 7 at 21,272,825 bp
  • T to A, chromosome 7 at 31,035,151 bp
  • G to A, chromosome 7 at 56,279,538 bp
  • T to A, chromosome 7 at 86,694,804 bp
  • T to C, chromosome 7 at 103,051,630 bp
  • C to T, chromosome 7 at 107,794,433 bp
  • T to A, chromosome 7 at 109,460,244 bp
  • A to G, chromosome 7 at 133,759,477 bp
  • T to A, chromosome 8 at 54,632,487 bp
  • G to T, chromosome 8 at 109,940,188 bp
  • A to T, chromosome 9 at 35,189,034 bp
  • T to A, chromosome 9 at 70,543,965 bp
  • C to T, chromosome 9 at 72,452,815 bp
  • T to A, chromosome 9 at 108,069,029 bp
  • C to A, chromosome 10 at 80,806,653 bp
  • G to A, chromosome 10 at 121,413,019 bp
  • A to G, chromosome 10 at 128,944,413 bp
  • C to T, chromosome 10 at 129,046,455 bp
  • T to A, chromosome 10 at 129,912,287 bp
  • A to G, chromosome 11 at 49,626,009 bp
  • T to A, chromosome 11 at 61,684,753 bp
  • A to G, chromosome 11 at 67,181,150 bp
  • A to T, chromosome 11 at 68,992,959 bp
  • T to A, chromosome 11 at 77,137,779 bp
  • A to T, chromosome 11 at 95,678,091 bp
  • T to C, chromosome 12 at 69,202,910 bp
  • T to C, chromosome 12 at 69,741,669 bp
  • A to G, chromosome 12 at 100,842,738 bp
  • A to T, chromosome 12 at 105,164,531 bp
  • T to A, chromosome 13 at 4,088,966 bp
  • A to G, chromosome 13 at 21,133,257 bp
  • T to C, chromosome 13 at 63,573,294 bp
  • T to G, chromosome 13 at 76,056,466 bp
  • T to C, chromosome 14 at 20,747,839 bp
  • G to T, chromosome 14 at 21,052,671 bp
  • T to G, chromosome 14 at 32,177,369 bp
  • T to G, chromosome 14 at 34,065,849 bp
  • T to A, chromosome 14 at 47,500,872 bp
  • A to T, chromosome 14 at 54,972,490 bp
  • G to A, chromosome 15 at 82,289,213 bp
  • G to A, chromosome 16 at 91,926,867 bp
  • T to A, chromosome 17 at 27,118,561 bp
  • A to G, chromosome 17 at 34,113,822 bp
  • A to G, chromosome 17 at 34,716,501 bp
  • A to G, chromosome 17 at 37,023,127 bp
  • T to A, chromosome 18 at 21,008,693 bp
  • A to T, chromosome 18 at 36,679,616 bp
  • A to G, chromosome 18 at 37,687,398 bp
  • T to A, chromosome 18 at 86,716,734 bp
  • A to G, chromosome 19 at 3,266,405 bp
  • T to A, chromosome 19 at 8,925,738 bp
  • T to A, chromosome 19 at 25,127,085 bp
  • C to T, chromosome 19 at 26,654,464 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7257 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045318-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.