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Strain Name:
C57BL/6J-MtgxR7164Btlr/Mmmh
Stock Number:
045331-MU
Citation ID:
RRID:MMRRC_045331-MU
Other Names:
R7164 (G1)
Major Collection:

Strain Information

Myo5a
Name: myosin VA
Synonyms: MVa, MyoVA, Myo5, flail, 9630007J19Rik, Dbv
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17918
HGNC: HGNC:7602
Homologene: 20100
Map4k5
Name: mitogen-activated protein kinase kinase kinase kinase 5
Synonyms: MAPKKKK5, GCKR, KHS, 4432415E19Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 399510
HGNC: HGNC:6867
Homologene: 38199
Cdk17
Name: cyclin dependent kinase 17
Synonyms: 6430598J10Rik, Pctk2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237459
VEGA: 10
HGNC: HGNC:8750
Homologene: 55666
Espl1
Name: extra spindle pole bodies 1, separase
Synonyms: separase, SSE, ESP1, PRCE, PRCE, Cerp
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105988
VEGA: 15
Homologene: 32151
Manba
Name: mannosidase, beta A, lysosomal
Synonyms: Bmn, 2410030O07Rik, B930014J03Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 110173
HGNC: HGNC:6831
Homologene: 4317
Map4k4
Name: mitogen-activated protein kinase kinase kinase kinase 4
Synonyms: Nik, 9430080K19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 26921
HGNC: HGNC:6866
Homologene: 7442
Mtf2
Name: metal response element binding transcription factor 2
Synonyms: M96, 9230112N11Rik, C76717, Pcl2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 17765
Homologene: 7207
Akap9
Name: A kinase anchor protein 9
Synonyms: AKAP450, 5730481H23Rik, G1-448-15, repro12, mei2-5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Anapc2
Name: anaphase promoting complex subunit 2
Synonyms: expressed during mesenchymal induction 4, Emi4, APC2, 9230107K09Rik, Imi4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99152
Homologene: 8359
Usp10
Name: ubiquitin specific peptidase 10
Synonyms: Uchrp, 2610014N07Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 22224
Homologene: 31294
Slc44a1
Name: solute carrier family 44, member 1
Synonyms: CHTL1, CTL1, 4833416H08Rik, Cdw92, 2210409B22Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100434
Homologene: 11137
Cit
Name: citron
Synonyms: CRIK-SK, citron-N, citron kinase, Cit-k, C030025P15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12704
HGNC: HGNC:1985
Homologene: 21404
Zfp318
Name: zinc finger protein 318
Synonyms: TZF, 2610034E08Rik, D530032D06Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 57908
Homologene: 22808
Bcl6
Name: B cell leukemia/lymphoma 6
Synonyms: Bcl5
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12053
HGNC: HGNC:1001
Homologene: 7640
Ptprc
Name: protein tyrosine phosphatase receptor type C
Synonyms: T200, B220, CD45, Lyt-4, Ly-5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19264
HGNC: HGNC:9666
Homologene: 2126
Prr14l
Name: proline rich 14-like
Synonyms: 6030436E02Rik, C330019G07Rik, Prl14l
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 215476
Homologene: 65866
Gpr89
Name: G protein-coupled receptor 89
Synonyms: SH120, 4933412D19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67549
Homologene: 9475
Degs1
Name: delta 4-desaturase, sphingolipid 1
Synonyms: Mdes, Des1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13244
Homologene: 55770
Nhlrc2
Name: NHL repeat containing 2
Synonyms: 1200003G01Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66866
VEGA: 19
Homologene: 12048
Kcnab3
Name: potassium voltage-gated channel, shaker-related subfamily, beta member 3
Synonyms: mKv(beta)4, Kcnab4, C330022D06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16499
HGNC: HGNC:6230
Homologene: 55844
Klk4
Name: kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)
Synonyms: KLK-L1, ESMP1, Prss17
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56640
HGNC: HGNC:6365
Homologene: 55856
Pde4d
Name: phosphodiesterase 4D, cAMP specific
Synonyms: dunce, Dpde3, 9630011N22Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238871
HGNC: HGNC:8783
Myo16
Name: myosin XVI
Synonyms: C230040D10Rik, Nyap3, BM140241
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244281
Homologene: 34710
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: PC6, SPC6, PC5A, PC5/6A, b2b585Clo, b2b1549Clo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Chd3
Name: chromodomain helicase DNA binding protein 3
Synonyms: Mi-2 alpha, Prp9-1, Prp7, 2600010P09Rik, Chd7
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216848
HGNC: HGNC:1918
Homologene: 62693
Cfap206
Name: cilia and flagella associated protein 206
Synonyms: 1700003M02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69329
Homologene: 18713
Carmil3
Name: capping protein regulator and myosin 1 linker 3
Synonyms: Lrrc16b
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268747
VEGA: 14
Homologene: 74564
Prmt6
Name: protein arginine N-methyltransferase 6
Synonyms: Hrmt1l6
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99890
Homologene: 10024
Fbxl4
Name: F-box and leucine-rich repeat protein 4
Synonyms: FBL5, FBL4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269514
Homologene: 8128
Actn2
Name: actinin alpha 2
Synonyms: 1110008F24Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 11472
HGNC: HGNC:164
Homologene: 31016
Vmn2r75
Name: vomeronasal 2, receptor 75
Synonyms: EG546981
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 546981
Homologene: 115466
Pth1r
Name: parathyroid hormone 1 receptor
Synonyms: PPR, PTH-related peptide receptor, PTH1R, PTH/PTHrP receptor, Pthr1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19228
HGNC: HGNC:9608
Homologene: 267
Or10ak9
Name: olfactory receptor family 10 subfamily AK member 9
Synonyms: GA_x6K02T2QD9B-18670866-18669913, MOR259-3P, Olfr1331
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 258159
Homologene: 134082
Spag16
Name: sperm associated antigen 16
Synonyms: Pf20, 4930524F24Rik, 4930585K05Rik, Wdr29, 4921511D23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66722
Homologene: 11572
Pld5
Name: phospholipase D family member 5
Synonyms: B230365F16Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 319455
Homologene: 16081
Or1j21
Name: olfactory receptor family 1 subfamily J member 21
Synonyms: ID3, MOR136-6, GA_x6K02T2NLDC-33487752-33488690, Olfr50
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18350
Homologene: 74212
Slco1c1
Name: solute carrier organic anion transporter family, member 1c1
Synonyms: OATP-F, Slc21a14
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 58807
Homologene: 23008
Spata31h1
Name: SPATA31 subfamily H member 1
Synonyms: 4932415D10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 102635990
VEGA: 10
Homologene: 82476
Gnptab
Name: N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
Synonyms: EG432486
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 432486
Homologene: 32576
Or5ae2
Name: olfactory receptor family 5 subfamily AE member 2
Synonyms: GA_x6K02T2NHDJ-11231385-11230438, MOR254-2, Olfr291
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258410
Homologene: 83130
Inpp5e
Name: inositol polyphosphate-5-phosphatase E
Synonyms: 1200002L24Rik, 72kDa
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 64436
Homologene: 56863
Mast1
Name: microtubule associated serine/threonine kinase 1
Synonyms: 9430008B02Rik, SAST170, SAST
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 56527
Homologene: 10543
Psg18
Name: pregnancy specific beta-1-glycoprotein 18
Synonyms: mmCGM6, Cea-3, Cea3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26438
HGNC: HGNC:9524
Homologene: 110989
Masp2
Name: MBL associated serine protease 2
Synonyms: MAp19, MASP-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17175
HGNC: HGNC:6902
Homologene: 4819
Ajm1
Name: apical junction component 1
Synonyms: LOC381353, Gm996
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381353
Homologene: 19943
Itga3
Name: integrin alpha 3
Synonyms: VLA-3 alpha 3, alpha3-integrin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16400
HGNC: HGNC:6139
Homologene: 21129
Zfp707
Name: zinc finger protein 707
Synonyms: 1500031N24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69020
Homologene: 18364
Nat1
Name: N-acetyl transferase 1
Synonyms: Nat-1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17960
Homologene: 115468
Igsf5
Name: immunoglobulin superfamily, member 5
Synonyms: 2010003D20Rik, Igsf5, Jam4
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 72058
HGNC: HGNC:5952
Homologene: 12437
Czib
Name: CXXC motif containing zinc binding protein
Synonyms: 0610037L13Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74098
Homologene: 41206
Zfp324
Name: zinc finger protein 324
Synonyms: D430030K24Rik, ZF5128
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243834
Homologene: 8648
Or5b108
Name: olfactory receptor family 5 subfamily B member 108
Synonyms: GA_x6K02T2RE5P-3517488-3518411, MOR202-13, Olfr1462
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258688
HGNC: HGNC:8324
Homologene: 133607
Lrrc73
Name: leucine rich repeat containing 73
Synonyms: LOC224813, Gm88
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224813
VEGA: 17
Homologene: 19183
Vmn2r113
Name: vomeronasal 2, receptor 113
Synonyms: EG434701
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 434701
Or8g51
Name: olfactory receptor family 8 subfamily G member 51
Synonyms: GA_x6K02T2PVTD-32400678-32399743, MOR171-23, Olfr919
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258432
VEGA: 9
Tas2r114
Name: taste receptor, type 2, member 114
Synonyms: Tas2r14, T2R14, mGR14, mt2r46
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387346
Homologene: 128355
Or5d20-ps1
Name: olfactory receptor family 5 subfamily D member 20, pseudogene 1
Synonyms: GA_x6K02T2Q125-49593880-49592930, MOR174-7, Olfr1165-ps
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258642
U2af1l4
Name: U2 small nuclear RNA auxiliary factor 1-like 4
Synonyms: auxiliary factor 26, U2af26
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233073
Homologene: 134014
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 39,973,972 bp
  • A to G, chromosome 1 at 70,724,866 bp
  • T to A, chromosome 1 at 138,117,862 bp
  • A to T, chromosome 1 at 176,213,621 bp
  • A to G, chromosome 1 at 182,279,125 bp
  • C to T, chromosome 2 at 25,284,999 bp
  • T to A, chromosome 2 at 25,578,567 bp
  • T to A, chromosome 2 at 26,407,983 bp
  • T to C, chromosome 2 at 36,793,697 bp
  • T to C, chromosome 2 at 88,101,832 bp
  • A to T, chromosome 3 at 96,871,398 bp
  • A to G, chromosome 3 at 110,250,364 bp
  • A to T, chromosome 3 at 135,542,388 bp
  • C to T, chromosome 4 at 22,386,218 bp
  • T to A, chromosome 4 at 34,719,656 bp
  • T to C, chromosome 4 at 53,528,711 bp
  • C to A, chromosome 4 at 107,894,890 bp
  • C to T, chromosome 4 at 118,869,725 bp
  • A to G, chromosome 4 at 148,610,115 bp
  • G to C, chromosome 5 at 4,060,364 bp
  • A to T, chromosome 5 at 32,829,166 bp
  • A to G, chromosome 5 at 87,674,228 bp
  • T to A, chromosome 5 at 108,093,369 bp
  • T to A, chromosome 5 at 115,985,787 bp
  • G to A, chromosome 6 at 131,689,765 bp
  • T to A, chromosome 6 at 141,542,129 bp
  • A to T, chromosome 7 at 12,968,883 bp
  • T to C, chromosome 7 at 18,350,937 bp
  • T to C, chromosome 7 at 30,565,119 bp
  • T to C, chromosome 7 at 43,881,698 bp
  • A to G, chromosome 7 at 84,857,043 bp
  • A to C, chromosome 7 at 86,165,384 bp
  • A to T, chromosome 8 at 10,569,585 bp
  • T to C, chromosome 8 at 67,491,677 bp
  • T to C, chromosome 8 at 84,935,304 bp
  • T to C, chromosome 8 at 119,942,108 bp
  • A to G, chromosome 9 at 38,698,219 bp
  • A to G, chromosome 9 at 75,180,153 bp
  • A to G, chromosome 9 at 110,723,747 bp
  • G to A, chromosome 10 at 82,286,229 bp
  • T to A, chromosome 10 at 88,434,070 bp
  • T to G, chromosome 10 at 93,232,481 bp
  • T to C, chromosome 11 at 69,331,358 bp
  • T to G, chromosome 11 at 69,362,306 bp
  • C to T, chromosome 11 at 95,052,479 bp
  • T to C, chromosome 12 at 69,830,436 bp
  • G to A, chromosome 13 at 12,278,961 bp
  • A to G, chromosome 13 at 109,032,688 bp
  • A to G, chromosome 14 at 7,915,944 bp
  • A to G, chromosome 14 at 55,501,282 bp
  • A to G, chromosome 15 at 75,975,118 bp
  • T to C, chromosome 15 at 102,313,203 bp
  • G to A, chromosome 16 at 23,966,226 bp
  • A to T, chromosome 16 at 96,372,848 bp
  • A to G, chromosome 17 at 22,948,163 bp
  • T to C, chromosome 17 at 46,256,243 bp
  • T to A, chromosome 17 at 46,397,306 bp
  • T to C, chromosome 17 at 46,405,939 bp
  • A to T, chromosome 19 at 13,190,906 bp
  • C to T, chromosome 19 at 17,451,985 bp
  • A to G, chromosome 19 at 56,592,499 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7164 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045331-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.