Strain Name:
C57BL/6J-MtgxR7295Btlr/Mmmh
Stock Number:
045363-MU
Citation ID:
RRID:MMRRC_045363-MU
Other Names:
R7295 (G1)
Major Collection:

Strain Information

a
Name: nonagouti
Synonyms: agouti signal protein, As, ASP, agouti
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 50518
HGNC: HGNC:745
Homologene: 1264
Bmp7
Name: bone morphogenetic protein 7
Synonyms: OP1, osteogenic protein 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12162
HGNC: HGNC:1074
Homologene: 20410
Ntsr1
Name: neurotensin receptor 1
Synonyms: NTR1, NT-1R, NTR-1, Ntsr1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18216
HGNC: HGNC:8039
Homologene: 68261
Kcnj5
Name: potassium inwardly-rectifying channel, subfamily J, member 5
Synonyms: Kir3.4, GIRK4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 16521
VEGA: 9
HGNC: HGNC:6266
Homologene: 20248
Foxj2
Name: forkhead box J2
Synonyms: Fhx
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 60611
Homologene: 10187
Xpnpep3
Name: X-prolyl aminopeptidase 3, mitochondrial
Synonyms: E430012M05Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 321003
Eprs1
Name: glutamyl-prolyl-tRNA synthetase 1
Synonyms: Qprs, 3010002K18Rik, 2410081F06Rik, Eprs
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 107508
HGNC: HGNC:3418
Homologene: 5870
Gphn
Name: gephyrin
Synonyms: geph, 5730552E08Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 268566
VEGA: 12
Homologene: 10820
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: Loa, dynein heavy chain, retrograde transport, Dnchc1, Swl, MAP1C, 9930018I23Rik, Dnec1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
Rarb
Name: retinoic acid receptor, beta
Synonyms: RAR beta 2, Hap, RARbeta2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218772
VEGA: 14
HGNC: HGNC:9865
Homologene: 68100
Nop14
Name: NOP14 nucleolar protein
Synonyms: Nol14, 2610033H07Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75416
Homologene: 41773
Nsmaf
Name: neutral sphingomyelinase (N-SMase) activation associated factor
Synonyms: Fan, factor associated with N-SMase activation
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18201
HGNC: HGNC:8017
Homologene: 2652
Rad51
Name: RAD51 recombinase
Synonyms: Reca, Rad51a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19361
HGNC: HGNC:9817
Homologene: 2155
Zfp592
Name: zinc finger protein 592
Synonyms: A730014M16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233410
Homologene: 8759
Zfp931
Name: zinc finger protein 931
Synonyms: 2810021G02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 353208
Homologene: 136272
Prune2
Name: prune homolog 2
Synonyms: Olfaxin, A330102H22Rik, A230083H22Rik, 6330414G02Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 353211
VEGA: 19
Homologene: 18939
Alb
Name: albumin
Synonyms: Alb1, Alb-1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11657
HGNC: HGNC:399
Homologene: 405
Hbs1l
Name: Hbs1-like (S. cerevisiae)
Synonyms: eRFS, 2810035F15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 56422
VEGA: 10
HGNC: HGNC:4834
Homologene: 68525
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Ttc16
Name: tetratricopeptide repeat domain 16
Synonyms: 1200002K10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 338348
Homologene: 17011
Or8b1c
Name: olfactory receptor family 8 subfamily B member 1C
Synonyms: Olfr905, MOR167-1, GA_x6K02T2PVTD-32165709-32166641
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258800
VEGA: 9
Homologene: 110524
Lonp1
Name: lon peptidase 1, mitochondrial
Synonyms: 1200017E13Rik, Prss15, LON
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74142
VEGA: 17
HGNC: HGNC:9479
Homologene: 3521
Slc22a1
Name: solute carrier family 22 (organic cation transporter), member 1
Synonyms: Orct, Oct1, Lx1, Orct1, Oct1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20517
VEGA: 17
Homologene: 20665
Rad9b
Name: RAD9 checkpoint clamp component B
Synonyms: A630082N15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231724
Homologene: 17006
Bpifb9a
Name: BPI fold containing family B, member 9A
Synonyms: vomeromodulin, 4833413D08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71425
Homologene: 128535
Sult1e1
Name: sulfotransferase family 1E, member 1
Synonyms: EST, Ste
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20860
Homologene: 101388
Adamts19
Name: ADAM metallopeptidase with thrombospondin type 1 motif 19
Synonyms: D230034E10Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240322
VEGA: 18
Homologene: 15860
Baat
Name: bile acid-Coenzyme A: amino acid N-acyltransferase
Synonyms: BAT, taurine N-acyltransferase
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12012
HGNC: HGNC:932
Homologene: 1286
Frmpd1
Name: FERM and PDZ domain containing 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 666060
Homologene: 8939
Ccnd2
Name: cyclin D2
Synonyms: cD2, Vin1, 2600016F06Rik, Vin-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12444
HGNC: HGNC:1583
Homologene: 37525
Sdcbp2
Name: syndecan binding protein (syntenin) 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228765
Homologene: 9240
Fam171a2
Name: family with sequence similarity 171, member A2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217219
Homologene: 19144
Adck1
Name: aarF domain containing kinase 1
Synonyms: 2610005A10Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 72113
VEGA: 12
Homologene: 6493
Ercc6l2
Name: excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2
Synonyms: 0610007P08Rik, 1700019D06Rik, 9330134C04Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76251
Homologene: 32564
Ddx28
Name: DEAD box helicase 28
Synonyms: 2410004K13Rik, Mddx28, DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71986
Homologene: 10164
Acp7
Name: acid phosphatase 7, tartrate resistant
Synonyms: Papl, C330005M16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101744
Homologene: 23924
Ssbp2
Name: single-stranded DNA binding protein 2
Synonyms: Hspc116, 1500004K09Rik, A830008M03Rik, 2310079I02Rik, 9330163K02Rik, Ssdp2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66970
Homologene: 22724
Myod1
Name: myogenic differentiation 1
Synonyms: Myod-1, MyoD, MYF3, bHLHc1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17927
HGNC: HGNC:7611
Homologene: 7857
Cbfa2t3
Name: CBFA2/RUNX1 translocation partner 3
Synonyms: ETO-2, Eto2, A630044F12Rik, MTGR2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12398
HGNC: HGNC:1537
Homologene: 74543
Clip1
Name: CAP-GLY domain containing linker protein 1
Synonyms: cytoplasmic linker protein 50, restin, Clip 170, Clip50, Rsn, 4631429H07Rik, 1110007I12Rik, CLIP-170
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56430
Homologene: 74455
Gtpbp3
Name: GTP binding protein 3
Synonyms: Gtpbp3, 2410009F13Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 70359
Homologene: 6600
Il22b
Name: interleukin 22B
Synonyms: IL-TIFb, Iltifb
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 116849
Homologene: 9669
Mgst1
Name: microsomal glutathione S-transferase 1
Synonyms: 1500002K10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56615
HGNC: HGNC:7061
Homologene: 10544
Muc21
Name: mucin 21
Synonyms: Gm9573, epiglycanin
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 672682
Klhl11
Name: kelch-like 11
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217194
Homologene: 10030
Prps1l1
Name: phosphoribosyl pyrophosphate synthetase 1-like 1
Synonyms: 1700011K15Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75456
HGNC: HGNC:9463
Homologene: 75282
Gfm1
Name: G elongation factor, mitochondrial 1
Synonyms: D3Wsu133e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 28030
Homologene: 6449
Usp16
Name: ubiquitin specific peptidase 16
Synonyms: 1200004E02Rik, 2810483I07Rik, 6330514E22Rik, UBP-M
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74112
Homologene: 38183
Edil3
Name: EGF-like repeats and discoidin I-like domains 3
Synonyms: Del-1, developmental endothelial locus-1, Del1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 13612
HGNC: HGNC:3173
Homologene: 21166
Spon1
Name: spondin 1, (f-spondin) extracellular matrix protein
Synonyms: D330035F22Rik, FSP
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233744
Homologene: 4453
Or4k6
Name: olfactory receptor family 4 subfamily K member 6
Synonyms: GA_x6K02T2PMLR-5936117-5935137, MOR246-5, Olfr731
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258360
Homologene: 84579
Hoxc12
Name: homeobox C12
Synonyms: Hox-3.8
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 15421
HGNC: HGNC:5124
Homologene: 7769
Slc35f1
Name: solute carrier family 35, member F1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215085
Homologene: 33552
Qpctl
Name: glutaminyl-peptide cyclotransferase-like
Synonyms: 1810019P04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67369
Homologene: 9765
H2bc8
Name: H2B clustered histone 8
Synonyms: Hist1h2bg
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 319181
Homologene: 136774
Pcdha6
Name: protocadherin alpha 6
Synonyms: Crnr2, Cnr2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12937
Homologene: 75098
Pcdha11
Name: protocadherin alpha 11
Synonyms: A830022B16Rik, Cnr7, Crnr7
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12942
HGNC: HGNC:8665
Homologene: 75095
Myocos
Name: myocilin opposite strand
Synonyms: 7420461P10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 100038657
Utp3
Name: UTP3 small subunit processome component
Synonyms: 2400011K09Rik, Crlz1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 65961
Homologene: 10681
Traj32
Name: T cell receptor alpha joining 32
Synonyms: Gm16667
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100124357
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 162,657,118 bp
  • A to G, chromosome 1 at 185,418,210 bp
  • T to C, chromosome 2 at 32,774,425 bp
  • T to A, chromosome 2 at 76,726,555 bp
  • T to A, chromosome 2 at 76,946,129 bp
  • C to T, chromosome 2 at 119,134,118 bp
  • T to A, chromosome 2 at 125,335,487 bp
  • T to C, chromosome 2 at 151,587,401 bp
  • C to T, chromosome 2 at 154,267,696 bp
  • A to T, chromosome 2 at 155,045,758 bp
  • A to T, chromosome 2 at 172,939,897 bp
  • A to T, chromosome 2 at 178,068,031 bp
  • A to T, chromosome 2 at 180,500,932 bp
  • G to A, chromosome 3 at 67,440,181 bp
  • A to G, chromosome 4 at 6,438,083 bp
  • A to G, chromosome 4 at 45,285,700 bp
  • A to T, chromosome 4 at 49,490,275 bp
  • C to T, chromosome 5 at 34,639,032 bp
  • T to A, chromosome 5 at 87,578,653 bp
  • G to C, chromosome 5 at 88,554,517 bp
  • T to A, chromosome 5 at 90,462,834 bp
  • A to G, chromosome 5 at 122,334,278 bp
  • G to T, chromosome 5 at 123,627,356 bp
  • T to C, chromosome 6 at 122,840,231 bp
  • A to T, chromosome 6 at 127,148,762 bp
  • A to T, chromosome 6 at 138,147,756 bp
  • A to T, chromosome 7 at 19,149,130 bp
  • A to T, chromosome 7 at 28,629,530 bp
  • A to G, chromosome 7 at 46,378,219 bp
  • G to T, chromosome 7 at 81,024,322 bp
  • A to T, chromosome 7 at 114,030,240 bp
  • C to A, chromosome 8 at 71,489,495 bp
  • G to A, chromosome 8 at 106,010,844 bp
  • T to G, chromosome 8 at 122,638,029 bp
  • T to C, chromosome 9 at 32,322,791 bp
  • A to T, chromosome 9 at 38,473,443 bp
  • T to C, chromosome 10 at 21,310,152 bp
  • G to A, chromosome 10 at 53,062,541 bp
  • A to T, chromosome 10 at 118,294,943 bp
  • A to G, chromosome 11 at 100,472,242 bp
  • T to C, chromosome 11 at 102,438,238 bp
  • T to A, chromosome 12 at 34,985,680 bp
  • T to C, chromosome 12 at 78,492,102 bp
  • G to T, chromosome 12 at 88,431,045 bp
  • T to C, chromosome 12 at 110,664,749 bp
  • T to C, chromosome 13 at 23,571,769 bp
  • T to G, chromosome 13 at 63,819,775 bp
  • T to A, chromosome 13 at 89,131,783 bp
  • T to A, chromosome 13 at 91,694,003 bp
  • A to T, chromosome 14 at 16,508,932 bp
  • T to C, chromosome 14 at 50,238,616 bp
  • T to A, chromosome 14 at 54,186,149 bp
  • A to G, chromosome 15 at 81,414,534 bp
  • A to G, chromosome 15 at 102,938,375 bp
  • G to A, chromosome 16 at 87,472,089 bp
  • T to A, chromosome 17 at 12,657,005 bp
  • G to A, chromosome 17 at 35,618,869 bp
  • G to T, chromosome 17 at 56,622,495 bp
  • T to A, chromosome 18 at 36,968,136 bp
  • T to C, chromosome 18 at 37,006,926 bp
  • T to A, chromosome 18 at 58,837,883 bp
  • A to G, chromosome 19 at 17,119,897 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7295 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045363-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.