Strain Name:
C57BL/6J-MtgxR7837Btlr/Mmmh
Stock Number:
045891-MU
Citation ID:
RRID:MMRRC_045891-MU
Other Names:
R7837 (G1)
Major Collection:

Strain Information

Sptbn1
Name: spectrin beta, non-erythrocytic 1
Synonyms: 9930031C03Rik, brain spectrin, elf1, spectrin G, beta fodrin, Spnb2, non-erythrocytic, Spnb-2, elf3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20742
Homologene: 2354
Gria2
Name: glutamate receptor, ionotropic, AMPA2 (alpha 2)
Synonyms: GluA2, Glur2, GluR2, GluR-B, Glur-2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14800
HGNC: HGNC:4572
Homologene: 20225
Cemip2
Name: cell migration inducing hyaluronidase 2
Synonyms: 3110012M15Rik, Tmem2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 83921
VEGA: 19
Homologene: 75008
Mbd4
Name: methyl-CpG binding domain protein 4
Synonyms: Med1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17193
HGNC: HGNC:6919
Homologene: 2916
Zbtb43
Name: zinc finger and BTB domain containing 43
Synonyms: Zfp297b, 1700010E06Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71834
Homologene: 8514
Armc1
Name: armadillo repeat containing 1
Synonyms: Arcp, 2900046P06Rik, C330014L16Rik, 2310016N05Rik, 3110009G21Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74252
Homologene: 10015
Septin7
Name: septin 7
Synonyms: Sept7, Cdc10
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235072
VEGA: 9
HGNC: HGNC:1717
Homologene: 1354
Msr1
Name: macrophage scavenger receptor 1
Synonyms: SR-AII, SR-AI, MRS-A, Scara1, MSR-A, Scvr
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20288
HGNC: HGNC:7376
Homologene: 12822
Ttll4
Name: tubulin tyrosine ligase-like family, member 4
Synonyms: 4632407P03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67534
Homologene: 8764
Mrgpra1
Name: MAS-related GPR, member A1
Synonyms: MrgA1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233221
Homologene: 79615
Bcl2
Name: B cell leukemia/lymphoma 2
Synonyms: C430015F12Rik, Bcl-2, D830018M01Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12043
HGNC: HGNC:990
Homologene: 527
Msh6
Name: mutS homolog 6
Synonyms: GTBP, Msh6, Gtmbp
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17688
VEGA: 17
HGNC: HGNC:7329
Homologene: 149
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: LOC381562, A930005E13Rik, D930005K06Rik, Zubr1, p600, 1810009A16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69116
Homologene: 10804
Crispld1
Name: cysteine-rich secretory protein LCCL domain containing 1
Synonyms: Cocoacrisp
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 83691
Homologene: 12857
Zfp59
Name: zinc finger protein 59
Synonyms: Mfg2, Mfg-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22717
Homologene: 137243
Zdhhc12
Name: zinc finger, DHHC domain containing 12
Synonyms: 1190004A01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66220
Homologene: 11934
Zkscan8
Name: zinc finger with KRAB and SCAN domains 8
Synonyms: Zfp192, LD5-1, D430019P06Rik, 2510038J07Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 93681
Homologene: 21268
Akap2
Name: A kinase (PRKA) anchor protein 2
Synonyms: B230340M18Rik, AKAP-KL
Type: Gene
Species: Mouse
Chromosome: 4
Anapc4
Name: anaphase promoting complex subunit 4
Synonyms: D5Ertd249e, APC4, 2610306D21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 52206
Homologene: 40873
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Tarbp1
Name: TAR RNA binding protein 1
Synonyms: Gm17296
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212728
Homologene: 38082
F5
Name: coagulation factor V
Synonyms: Cf-5, Cf5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Dnahc12, HL19, DLP12, LOC380889, Dnahc7l, 4921531P07Rik, Hdhc3, DHC3, HL-19
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Adgrb3
Name: adhesion G protein-coupled receptor B3
Synonyms: Bai3, A830096D10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210933
HGNC: HGNC:945
Homologene: 1289
Pcnx4
Name: pecanex homolog 4
Synonyms: Pcnxl4, 1810048J11Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 67708
VEGA: 12
Homologene: 23366
Zfp943
Name: zinc finger prtoein 943
Synonyms: 4930432O21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74670
Homologene: 134342
Stard9
Name: StAR related lipid transfer domain containing 9
Synonyms: Kif16a, E230025N21Rik, 4831403C07Rik, N-3 kinesin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668880
Homologene: 130712
Slc4a5
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 5
Synonyms: C330016K18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232156
Homologene: 31125
Aadacl4
Name: arylacetamide deacetylase like 4
Synonyms: Gm13177
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 435815
Homologene: 82530
Ogdhl
Name: oxoglutarate dehydrogenase-like
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239017
VEGA: 14
Homologene: 56801
Gm19410
Name: predicted gene, 19410
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 100502846
Homologene: 132117
Dnm3
Name: dynamin 3
Synonyms: 9630020E24Rik, B230343F03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 103967
Homologene: 22906
Kcnh6
Name: potassium voltage-gated channel, subfamily H (eag-related), member 6
Synonyms: m-erg2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192775
Homologene: 32740
Aoc1
Name: amine oxidase, copper-containing 1
Synonyms: 1600012D06Rik, Abp1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 76507
HGNC: HGNC:80
Homologene: 68159
Rin3
Name: Ras and Rab interactor 3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217835
Homologene: 11748
Or4c102
Name: olfactory receptor family 4 subfamily C member 102
Synonyms: Olfr1189, GA_x6K02T2Q125-50079044-50079964, MOR237-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258768
Homologene: 81569
Adam22
Name: a disintegrin and metallopeptidase domain 22
Synonyms: MDC2, 2900022I03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11496
HGNC: HGNC:201
Homologene: 37898
Nr1i2
Name: nuclear receptor subfamily 1, group I, member 2
Synonyms: PXR.2, mPXR, PXR, PXR.1, Pregnane X receptor, SXR
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 18171
HGNC: HGNC:7968
Homologene: 40757
Tssk2
Name: testis-specific serine kinase 2
Synonyms: Tsk2, SPOGA2, DGS-G, Stk22b
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 22115
VEGA: 16
Homologene: 31512
Cenpj
Name: centromere protein J
Synonyms: Sas4, 4932437H03Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219103
Homologene: 10204
Krt82
Name: keratin 82
Synonyms: Krt2-20
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 114566
VEGA: 15
HGNC: HGNC:6459
Homologene: 13200
Sgk2
Name: serum/glucocorticoid regulated kinase 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27219
Homologene: 8446
Tex56
Name: testis expressed 56
Synonyms: 4933417A18Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66761
Homologene: 23555
Plscr4
Name: phospholipid scramblase 4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235527
Homologene: 23217
Ecd
Name: ecdysoneless cell cycle regulator
Synonyms: 5730461K03Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 70601
VEGA: 14
Homologene: 5256
Pgap4
Name: post-GPI attachment to proteins GalNAc transferase 4
Synonyms: Tmem246, 9330170P15Rik, 2810432L12Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67063
Homologene: 12080
Or13a21
Name: olfactory receptor family 13 subfamily A member 21
Synonyms: Olfr532, MOR251-1, GA_x6K02T2PBJ9-42570051-42569122
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259028
Homologene: 133605
Or4k15b
Name: olfactory receptor family 4 subfamily K member 15B
Synonyms: MOR246-3, Olfr725, MOR246-7_p, GA_x6K02T2PMLR-5725741-5724776
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258314
Homologene: 44957
Wscd2
Name: WSC domain containing 2
Synonyms: C530024P05Rik, 4933413A10Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320916
Homologene: 35372
Cage1
Name: cancer antigen 1
Synonyms: Ctag3, 4933427I01Rik, CAGE1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 71213
Homologene: 18484
Dtx3l
Name: deltex 3-like, E3 ubiquitin ligase
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 209200
Homologene: 51375
Igkv13-84
Name: immunoglobulin kappa chain variable 13-84
Synonyms: Igk-V33
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 692152
Or51ag1
Name: olfactory receptor family 51 subfamily AG member 1
Synonyms: GA_x6K02T2PBJ9-6221839-6220892, Olfr610, MOR9-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259085
Homologene: 17495
Cln6
Name: ceroid-lipofuscinosis, neuronal 6
Synonyms: 1810065L06Rik, D9Bwg1455e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76524
HGNC: HGNC:2077
Homologene: 9898
Krtap5-20
Name: keratin associated protein 5-20
Synonyms: Gm4559
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100043627
VEGA: 7
Btd
Name: biotinidase
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 26363
HGNC: HGNC:1122
Homologene: 37255
Acox3
Name: acyl-Coenzyme A oxidase 3, pristanoyl
Synonyms: pristanoyl-CoA oxidase, EST-s59, PCOX
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 80911
HGNC: HGNC:121
Homologene: 37792
Dusp28
Name: dual specificity phosphatase 28
Synonyms: 0710001B24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67446
Homologene: 45491
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 17,728,730 bp
  • T to C, chromosome 1 at 25,128,834 bp
  • A to T, chromosome 1 at 74,681,757 bp
  • A to G, chromosome 1 at 92,907,683 bp
  • A to C, chromosome 1 at 106,543,356 bp
  • C to T, chromosome 1 at 161,992,050 bp
  • G to A, chromosome 1 at 164,186,794 bp
  • A to T, chromosome 2 at 30,091,697 bp
  • C to T, chromosome 2 at 33,453,969 bp
  • A to T, chromosome 2 at 88,592,379 bp
  • A to G, chromosome 2 at 120,703,665 bp
  • A to G, chromosome 2 at 163,003,296 bp
  • A to T, chromosome 3 at 19,144,469 bp
  • A to T, chromosome 3 at 80,710,788 bp
  • A to T, chromosome 4 at 49,586,262 bp
  • A to G, chromosome 4 at 57,855,262 bp
  • C to T, chromosome 4 at 139,393,151 bp
  • T to C, chromosome 4 at 144,617,977 bp
  • T to A, chromosome 5 at 8,149,284 bp
  • A to G, chromosome 5 at 35,611,486 bp
  • T to A, chromosome 5 at 52,859,208 bp
  • G to T, chromosome 5 at 113,572,333 bp
  • T to A, chromosome 6 at 48,905,650 bp
  • C to T, chromosome 6 at 68,939,809 bp
  • A to T, chromosome 6 at 83,261,557 bp
  • T to C, chromosome 6 at 115,849,539 bp
  • GAAA to GAAAAA, chromosome 7 at 27,854,917 bp
  • A to T, chromosome 7 at 47,335,328 bp
  • A to T, chromosome 7 at 103,506,845 bp
  • T to C, chromosome 7 at 140,419,321 bp
  • A to G, chromosome 7 at 141,815,963 bp
  • C to T, chromosome 7 at 142,273,816 bp
  • A to T, chromosome 8 at 35,808,980 bp
  • C to T, chromosome 8 at 39,581,832 bp
  • T to C, chromosome 8 at 126,474,561 bp
  • T to A, chromosome 9 at 25,288,235 bp
  • T to C, chromosome 9 at 62,849,048 bp
  • T to A, chromosome 9 at 92,484,923 bp
  • A to G, chromosome 11 at 30,138,832 bp
  • C to A, chromosome 11 at 106,033,810 bp
  • C to A, chromosome 12 at 72,556,118 bp
  • A to G, chromosome 12 at 102,368,765 bp
  • T to A, chromosome 13 at 21,520,428 bp
  • A to T, chromosome 13 at 34,944,376 bp
  • A to T, chromosome 13 at 38,022,405 bp
  • A to T, chromosome 14 at 20,333,332 bp
  • A to G, chromosome 14 at 26,796,219 bp
  • C to A, chromosome 14 at 31,666,827 bp
  • T to C, chromosome 14 at 32,346,458 bp
  • T to A, chromosome 14 at 50,034,576 bp
  • T to C, chromosome 14 at 56,558,728 bp
  • T to C, chromosome 15 at 101,548,357 bp
  • T to C, chromosome 16 at 17,898,751 bp
  • T to A, chromosome 16 at 35,931,526 bp
  • T to C, chromosome 16 at 38,253,784 bp
  • A to T, chromosome 17 at 21,992,365 bp
  • G to A, chromosome 17 at 87,984,666 bp
  • T to A, chromosome 19 at 21,798,021 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7837 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045891-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.