Strain Name:
C57BL/6J-MtgxR7889Btlr/Mmmh
Stock Number:
045941-MU
Citation ID:
RRID:MMRRC_045941-MU
Other Names:
R7889 (G1)
Major Collection:

Strain Information

Pds5b
Name: PDS5 cohesin associated factor B
Synonyms: Aprin, AS3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100710
Homologene: 41001
Nup155
Name: nucleoporin 155
Synonyms: D930027M19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 170762
VEGA: 15
HGNC: HGNC:8063
Homologene: 43155
Foxo3
Name: forkhead box O3
Synonyms: Foxo3a, 2010203A17Rik, Fkhr2, FKHRL1, 1110048B16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 56484
Homologene: 31039
Thrap3
Name: thyroid hormone receptor associated protein 3
Synonyms: Trap150, B230333E16Rik, 9330151F09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230753
Homologene: 31289
Xrcc5
Name: X-ray repair complementing defective repair in Chinese hamster cells 5
Synonyms: Ku86, Ku80
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22596
VEGA: 1
Homologene: 40681
Prmt3
Name: protein arginine N-methyltransferase 3
Synonyms: Hrmt1l3, 2410018A17Rik, 2010005E20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71974
Homologene: 24255
Afg2a
Name: AFG2 AAA ATPase homolog A
Synonyms: Spata5, 2510048F20Rik, Spaf, C78064
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 57815
Homologene: 56920
Ccdc14
Name: coiled-coil domain containing 14
Synonyms: G630039H03Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239839
VEGA: 16
Homologene: 32549
Dhx40
Name: DEAH-box helicase 40
Synonyms: 2410016C14Rik, ARG147, DDX40
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67487
Homologene: 57000
Sltm
Name: SAFB-like, transcription modulator
Synonyms: 9130215G10Rik, 5730455C01Rik, 5730555F13Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66660
VEGA: 9
Homologene: 11696
Ptcd3
Name: pentatricopeptide repeat domain 3
Synonyms: 2610034F17Rik, 2810422B04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 69956
Homologene: 41211
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: chromatin remodeling factor, E430018P19Rik, KMT2H, 8030453L17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192195
Homologene: 10225
Ipo9
Name: importin 9
Synonyms: 0710008K06Rik, Imp9
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226432
Homologene: 5874
Zfp626
Name: zinc finger protein 626
Synonyms: 4933426I21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71163
Helq
Name: helicase, POLQ-like
Synonyms: D430018E21Rik, Hel308
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 191578
Homologene: 14667
Ghsr
Name: growth hormone secretagogue receptor
Synonyms: Ghsr1a, C530020I22Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 208188
HGNC: HGNC:4267
Homologene: 57161
Csnk2a1-ps3
Name: casein kinase 2, alpha 1 polypeptide, pseudogene 3
Synonyms: Csnk2a1-rs3, Csnk2a3, Gm10031
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 100039026
Zfp799
Name: zinc finger protein 799
Synonyms: 6030490I01Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240064
Homologene: 107106
Hdc
Name: histidine decarboxylase
Synonyms: Hdc-s, Hdc-a, Hdc-c, Hdc-e, L-histidine decarboxylase
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15186
HGNC: HGNC:4855
Homologene: 20490
Gkn2
Name: gastrokine 2
Synonyms: Bricd1b, 1810036H07Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66284
Homologene: 11942
Angptl3
Name: angiopoietin-like 3
Synonyms: hypl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 30924
HGNC: HGNC:491
Homologene: 8499
Slc20a2
Name: solute carrier family 20, member 2
Synonyms: Pit-2, Ram-1, Ram1, PiT-2, MolPit2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20516
Homologene: 68531
Azi2
Name: 5-azacytidine induced gene 2
Synonyms: AZ2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 27215
Homologene: 8443
Cep72
Name: centrosomal protein 72
Synonyms: 4933440J22Rik, 2610029E11Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 74470
VEGA: 13
Homologene: 10027
Dync2i1
Name: dynein 2 intermediate chain 1
Synonyms: D430033N04Rik, Wdr60, Dync2l1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217935
VEGA: 12
Homologene: 23067
Fam13b
Name: family with sequence similarity 13, member B
Synonyms: 2610024E20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225358
VEGA: 18
HGNC: HGNC:1335
Homologene: 9585
Itpr3
Name: inositol 1,4,5-triphosphate receptor 3
Synonyms: tf, Itpr-3, Ip3r3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16440
HGNC: HGNC:6182
Homologene: 1675
Tnnt1
Name: troponin T1, skeletal, slow
Synonyms: sTnT, ssTnT, skeletal muscle slow-twitch TnT, Tnt
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21955
Homologene: 20704
Fastkd2
Name: FAST kinase domains 2
Synonyms: 2810421I24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75619
Homologene: 8957
Shtn1
Name: shootin 1
Synonyms: shootin1, 4930506M07Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 71653
VEGA: 19
Homologene: 41249
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b1537Clo, b2b1565Clo, Mdnah5, Dnahc5, b2b1134Clo, b2b1154Clo, b2b3491Clo
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Zfp831
Name: zinc finger protein 831
Synonyms: ENSMUSG00000050600, OTTMUSG00000017459
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 100043757
Homologene: 19013
Zcchc14
Name: zinc finger, CCHC domain containing 14
Synonyms: Bdg29
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 142682
Homologene: 9037
Trak2
Name: trafficking protein, kinesin binding 2
Synonyms: CALS-C, Als2cr3, 4733401O11Rik, GRIF-1, OIP98, 2900022D04Rik, GRIF1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70827
Homologene: 22861
Itga4
Name: integrin alpha 4
Synonyms: VLA-4 receptor, alpha 4 subunit
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16401
HGNC: HGNC:6140
Homologene: 37364
Ephb2
Name: Eph receptor B2
Synonyms: Nuk, Drt, Sek3, Tyro5, Cek5, Qek5, Hek5, Erk, Prkm5, eteck
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13844
HGNC: HGNC:3393
Homologene: 37925
Trp53i11
Name: transformation related protein 53 inducible protein 11
Synonyms: Tp53i11
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 277414
Homologene: 4404
Rabl6
Name: RAB, member RAS oncogene family-like 6
Synonyms: B230208H17Rik, Rbel1a, Rbel1b, Rbel1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227624
Homologene: 11674
Vinac1
Name: vinculin/alpha-catenin family member 1
Synonyms: Gm14025
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668894
Homologene: 86340
Stard9
Name: StAR related lipid transfer domain containing 9
Synonyms: N-3 kinesin, E230025N21Rik, Kif16a, 4831403C07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668880
Homologene: 130712
Clca3a2
Name: chloride channel accessory 3A2
Synonyms: Clca2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80797
HGNC: HGNC:2017
Homologene: 77224
Cap2
Name: cyclase associated actin cytoskeleton regulatory protein 2
Synonyms: 2810452G09Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 67252
Homologene: 101397
Spef2
Name: sperm flagellar 2
Synonyms: C230086A09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 320277
Homologene: 23371
Glyctk
Name: glycerate kinase
Synonyms: 6230410P16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235582
Homologene: 14738
Atp1a2
Name: ATPase, Na+/K+ transporting, alpha 2 polypeptide
Synonyms: Atpa-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98660
HGNC: HGNC:800
Homologene: 47947
Gadl1
Name: glutamate decarboxylase-like 1
Synonyms: 1110027M19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73748
Homologene: 45812
Galnt13
Name: polypeptide N-acetylgalactosaminyltransferase 13
Synonyms: pp-GalNAc-T13
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 271786
Homologene: 62167
Clcnkb
Name: chloride channel, voltage-sensitive Kb
Synonyms: Clcnk2, ClC-K2, Clck2, Clcnk1l
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56365
Homologene: 107317
Zfp616
Name: zinc finger protein 616
Synonyms: Gm12330
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327963
Homologene: 88945
Noxo1
Name: NADPH oxidase organizer 1
Synonyms: 2310034C04Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71893
Homologene: 12418
Llgl1
Name: LLGL1 scribble cell polarity complex component
Synonyms: Lgl1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16897
HGNC: HGNC:6628
Homologene: 31220
Fhod3
Name: formin homology 2 domain containing 3
Synonyms: A930009H06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225288
VEGA: 18
Homologene: 45323
Tmem150c
Name: transmembrane protein 150C
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231503
Homologene: 18818
Usp16
Name: ubiquitin specific peptidase 16
Synonyms: 2810483I07Rik, UBP-M, 1200004E02Rik, 6330514E22Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74112
Homologene: 38183
Nlrp4f
Name: NLR family, pyrin domain containing 4F
Synonyms: Nalp-kappa, C330026N02Rik, Nalp4f
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 97895
VEGA: 13
Homologene: 87252
Cyp2d9
Name: cytochrome P450, family 2, subfamily d, polypeptide 9
Synonyms: Cyp2d, P450-2D, testosterone 16alpha-hydroxylase
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 13105
VEGA: 15
Homologene: 86099
Fbxo40
Name: F-box protein 40
Synonyms: 9830003A13Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 207215
Homologene: 9459
Pla2g12b
Name: phospholipase A2, group XIIB
Synonyms: Pla2g13, 2010002E04Rik, hlb218
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 69836
Homologene: 11356
Oaf
Name: out at first homolog
Synonyms: D130038B21Rik, D9Ucla1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102644
VEGA: 9
Homologene: 14334
Art2a
Name: ADP-ribosyltransferase 2a
Synonyms: Rt6, Rt-6, Rt6-1, Art2a-ps
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11871
Gm5157
Name: predicted gene 5157
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381937
Homologene: 128656
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 58,918,824 bp
  • C to G, chromosome 1 at 63,735,460 bp
  • G to T, chromosome 1 at 72,356,826 bp
  • T to C, chromosome 1 at 135,406,853 bp
  • G to A, chromosome 1 at 156,525,395 bp
  • G to A, chromosome 1 at 172,278,064 bp
  • A to G, chromosome 2 at 25,584,774 bp
  • T to C, chromosome 2 at 52,147,669 bp
  • A to G, chromosome 2 at 55,112,861 bp
  • G to A, chromosome 2 at 79,316,045 bp
  • T to C, chromosome 2 at 93,198,899 bp
  • C to T, chromosome 2 at 120,704,461 bp
  • A to T, chromosome 2 at 126,616,210 bp
  • T to C, chromosome 2 at 129,036,994 bp
  • A to G, chromosome 2 at 174,645,304 bp
  • A to G, chromosome 3 at 27,372,166 bp
  • A to G, chromosome 3 at 37,578,810 bp
  • A to G, chromosome 3 at 88,966,038 bp
  • C to A, chromosome 3 at 144,810,813 bp
  • C to T, chromosome 4 at 99,031,071 bp
  • A to T, chromosome 4 at 126,178,062 bp
  • T to C, chromosome 4 at 136,771,042 bp
  • T to G, chromosome 4 at 141,410,604 bp
  • A to T, chromosome 5 at 100,093,104 bp
  • A to T, chromosome 5 at 100,792,561 bp
  • T to A, chromosome 5 at 150,792,172 bp
  • G to A, chromosome 6 at 71,888,608 bp
  • A to G, chromosome 6 at 87,378,286 bp
  • C to T, chromosome 7 at 4,508,583 bp
  • G to A, chromosome 7 at 21,184,716 bp
  • A to T, chromosome 7 at 27,819,499 bp
  • A to G, chromosome 7 at 49,787,301 bp
  • C to T, chromosome 7 at 101,555,211 bp
  • T to C, chromosome 8 at 22,540,401 bp
  • A to T, chromosome 8 at 121,604,895 bp
  • G to T, chromosome 9 at 43,222,671 bp
  • C to G, chromosome 9 at 70,586,673 bp
  • T to A, chromosome 9 at 106,156,439 bp
  • A to T, chromosome 9 at 115,954,815 bp
  • A to G, chromosome 9 at 118,061,915 bp
  • T to A, chromosome 10 at 42,275,027 bp
  • T to A, chromosome 10 at 59,421,240 bp
  • T to A, chromosome 11 at 60,707,312 bp
  • T to A, chromosome 11 at 74,085,445 bp
  • T to G, chromosome 11 at 86,798,967 bp
  • G to A, chromosome 12 at 113,131,688 bp
  • T to C, chromosome 12 at 114,945,963 bp
  • T to A, chromosome 12 at 116,255,939 bp
  • A to G, chromosome 13 at 46,646,575 bp
  • G to A, chromosome 13 at 65,195,018 bp
  • A to T, chromosome 13 at 74,050,122 bp
  • T to A, chromosome 15 at 8,121,507 bp
  • T to C, chromosome 15 at 9,717,563 bp
  • G to T, chromosome 15 at 28,448,414 bp
  • T to A, chromosome 15 at 82,455,826 bp
  • T to A, chromosome 16 at 34,723,836 bp
  • T to A, chromosome 16 at 36,969,650 bp
  • T to C, chromosome 16 at 87,474,584 bp
  • A to G, chromosome 17 at 24,699,382 bp
  • T to C, chromosome 17 at 27,116,777 bp
  • G to A, chromosome 17 at 32,819,499 bp
  • A to T, chromosome 18 at 24,770,494 bp
  • A to T, chromosome 18 at 34,457,691 bp
  • T to A, chromosome 19 at 59,003,896 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7889 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045941-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.