Strain Name:
C57BL/6J-MtgxR7911Btlr/Mmmh
Stock Number:
045960-MU
Citation ID:
RRID:MMRRC_045960-MU
Other Names:
R7911 (G1)
Major Collection:

Strain Information

Card11
Name: caspase recruitment domain family, member 11
Synonyms: CARMA1, BIMP3, 2410011D02Rik, 0610008L17Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 108723
Homologene: 13024
Kcnj5
Name: potassium inwardly-rectifying channel, subfamily J, member 5
Synonyms: Kir3.4, GIRK4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 16521
VEGA: 9
HGNC: HGNC:6266
Homologene: 20248
Arrdc4
Name: arrestin domain containing 4
Synonyms: 2410003C09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66412
Homologene: 41636
Jmjd1c
Name: jumonji domain containing 1C
Synonyms: TRIP8, 5430433L24Rik, D630035I23Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 108829
Homologene: 3129
Pum1
Name: pumilio RNA-binding family member 1
Synonyms: Pumm
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 80912
Homologene: 22830
B3galnt1
Name: UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
Synonyms: Mbrn 1, Brainiac 1, Globoside blood group, B3galt3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 26879
HGNC: HGNC:918
Homologene: 32457
Slk
Name: STE20-like kinase
Synonyms: 9A2, mSLK, Etk4, SLK, Stk2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20874
Homologene: 22515
Gart
Name: phosphoribosylglycinamide formyltransferase
Synonyms: Gaps, Prgs
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 14450
HGNC: HGNC:4163
Homologene: 637
Abcc8
Name: ATP-binding cassette, sub-family C member 8
Synonyms: SUR1, Sur, D930031B21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20927
HGNC: HGNC:59
Homologene: 68048
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, C130061D10Rik, Phr1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105689
Homologene: 9005
Ptpn21
Name: protein tyrosine phosphatase, non-receptor type 21
Synonyms: PTPD1, PTPRL10
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 24000
VEGA: 12
HGNC: HGNC:9651
Homologene: 5110
Mki67
Name: antigen identified by monoclonal antibody Ki 67
Synonyms: Ki-67, D630048A14Rik, Ki67
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17345
HGNC: HGNC:7107
Homologene: 1814
Prc1
Name: protein regulator of cytokinesis 1
Synonyms: D7Ertd348e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233406
HGNC: HGNC:9341
Homologene: 37868
Ipo5
Name: importin 5
Synonyms: RanBP5, 5730478E03Rik, 1110011C18Rik, Kpnb3, IMB3, importin beta 3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 70572
VEGA: 14
HGNC: HGNC:6402
Homologene: 1710
Gng4
Name: guanine nucleotide binding protein (G protein), gamma 4
Synonyms: 4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14706
HGNC: HGNC:4407
Homologene: 3299
Camkmt
Name: calmodulin-lysine N-methyltransferase
Synonyms: 1700106N22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 73582
VEGA: 17
Homologene: 11704
Usp53
Name: ubiquitin specific peptidase 53
Synonyms: Sp6, Phxr3, mbo
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99526
Homologene: 34521
Prdm15
Name: PR domain containing 15
Synonyms: Zfp298, E130018M06Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 114604
Homologene: 56941
Acbd6
Name: acyl-Coenzyme A binding domain containing 6
Synonyms: 0610010G04Rik, 2610100E10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72482
Homologene: 12465
Drg2
Name: developmentally regulated GTP binding protein 2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13495
HGNC: HGNC:3030
Homologene: 1061
Noct
Name: nocturnin
Synonyms: Ccr4, Ccrn4l
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12457
Homologene: 7661
Chst15
Name: carbohydrate sulfotransferase 15
Synonyms: GalNAcS-6ST, 4631426J05Rik, MAd5, MAd5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77590
Homologene: 8908
Dmrt1
Name: doublesex and mab-3 related transcription factor 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 50796
HGNC: HGNC:2934
Homologene: 9280
Ddhd2
Name: DDHD domain containing 2
Synonyms: SAMWD1, 2010305K11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72108
Homologene: 66646
Skor1
Name: SKI family transcriptional corepressor 1
Synonyms: C230094B15Rik, Corl1, Lbxcor1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 207667
Homologene: 18175
Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Synonyms: mtrp6, Trrp6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22068
VEGA: 9
Homologene: 37944
Abca3
Name: ATP-binding cassette, sub-family A member 3
Synonyms: ABC-C, Abc3, 1810036E22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 27410
HGNC: HGNC:33
Homologene: 37437
Cfap299
Name: cilia and flagella associated protein 299
Synonyms: 1700007G11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75784
Homologene: 51893
Vwa3b
Name: von Willebrand factor A domain containing 3B
Synonyms: A230074B11Rik, 4921511C04Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70853
Homologene: 27053
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Ptpn13
Name: protein tyrosine phosphatase, non-receptor type 13
Synonyms: PTP-BL, Ptpri, PTPL1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19249
HGNC: HGNC:9646
Homologene: 7909
Sorcs1
Name: sortilin-related VPS10 domain containing receptor 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 58178
Homologene: 10967
Ctu2
Name: cytosolic thiouridylase subunit 2
Synonyms: 2310061F22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66965
Homologene: 79815
Hsh2d
Name: hematopoietic SH2 domain containing
Synonyms: ALX, Hsh2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 209488
Homologene: 13142
Calcrl
Name: calcitonin receptor-like
Synonyms: CRLR
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 54598
Homologene: 21179
Scn2a
Name: sodium channel, voltage-gated, type II, alpha
Synonyms: Nav1.2, A230052E19Rik, Scn2a1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 110876
Homologene: 75001
Dscam
Name: DS cell adhesion molecule
Synonyms: 4932410A21Rik, Down syndrome cell adhesion molecule
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13508
HGNC: HGNC:3039
Homologene: 74393
Madd
Name: MAP-kinase activating death domain
Synonyms: 9630059K23Rik, Rab3 GEP
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228355
HGNC: HGNC:6766
Homologene: 14249
Farp1
Name: FERM, ARH/RhoGEF and pleckstrin domain protein 1
Synonyms: Cdep
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 223254
HGNC: HGNC:3591
Homologene: 38098
Mprip
Name: myosin phosphatase Rho interacting protein
Synonyms: RIP3, p116Rip, p116 Rho interacting protein, Rhoip3, Gm34094
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 26936
Homologene: 9034
Or5ac23
Name: olfactory receptor family 5 subfamily AC member 23
Synonyms: GA_x54KRFPKG5P-55543875-55542958, MOR182-11P, Olfr205
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 257881
Homologene: 79469
Heatr9
Name: HEAT repeat containing 9
Synonyms: Gm11435
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 629303
Homologene: 51895
Sh3pxd2b
Name: SH3 and PX domains 2B
Synonyms: G431001E03Rik, Fad49, Tks4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268396
Homologene: 27952
Ciao3
Name: cytosolic iron-sulfur assembly component 3
Synonyms: 9030612I22Rik, Narfl
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67563
Homologene: 6750
Zcwpw1
Name: zinc finger, CW type with PWWP domain 1
Synonyms: LOC381678
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381678
Homologene: 9944
Wdr90
Name: WD repeat domain 90
Synonyms: 3230401M21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106618
Homologene: 27066
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: LOC227058, Dnahc7b
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227058
Homologene: 41287
Ppip5k1
Name: diphosphoinositol pentakisphosphate kinase 1
Synonyms: B430315C20Rik, Hisppd2a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 327655
Homologene: 49395
Tex14
Name: testis expressed gene 14 intercellular bridge forming factor
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 83560
Homologene: 12838
Noa1
Name: nitric oxide associated 1
Synonyms: mAtNOS1, 2610024G14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56412
Homologene: 10518
Abcc2
Name: ATP-binding cassette, sub-family member 2
Synonyms: multidrug resistance protein 2, Mrp2, Cmoat
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12780
HGNC: HGNC:53
Homologene: 68052
Klk1b9
Name: kallikrein 1-related peptidase b9
Synonyms: mGk-9, Egfbp-3, Egfbp3, Klk9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13648
Homologene: 68141
Fbxo39
Name: F-box protein 39
Synonyms: 1700010H23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 628100
Homologene: 15156
Cryzl2
Name: crystallin zeta like 2
Synonyms: BC026585, quinone reductase-like 2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226527
Homologene: 41713
Col26a1
Name: collagen, type XXVI, alpha 1
Synonyms: Emu2, 9430032K24Rik, Collagen XXVI, Emid2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 140709
Homologene: 136636
Abca7
Name: ATP-binding cassette, sub-family A member 7
Synonyms: Abc51
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 27403
HGNC: HGNC:37
Homologene: 22783
1700028K03Rik
Name: RIKEN cDNA 1700028K03 gene
Synonyms: SCRE, Spo16
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76421
Homologene: 18810
Macir
Name: macrophage immunometabolism regulator
Synonyms: D1Ertd622e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 52392
Homologene: 13239
Cfap157
Name: cilia and flagella associated protein 157
Synonyms: 1700019L03Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227736
Homologene: 53056
Them5
Name: thioesterase superfamily member 5
Synonyms: 1110007B02Rik, 1110038F21Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66198
Homologene: 11931
Pdlim7
Name: PDZ and LIM domain 7
Synonyms: 2410002J21Rik, 1110003B01Rik, Enigma
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 67399
Homologene: 3980
Tlcd4
Name: TLC domain containing 4
Synonyms: C730036B01Rik, 4930577M16Rik, Tmem56
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99887
Homologene: 45107
Fbxl21
Name: F-box and leucine-rich repeat protein 21
Synonyms: FBXL3B, FBL3B, D630045D17Rik, Psttm
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 213311
Homologene: 78724
Igkv1-133
Name: immunoglobulin kappa variable 1-133
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 628027
Pcdhga6
Name: protocadherin gamma subfamily A, 6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93714
HGNC: HGNC:8704
Homologene: 129611
Trav5-4
Name: T cell receptor alpha variable 5-4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21507
Ankrd31
Name: ankyrin repeat domain 31
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 625662
Homologene: 110355
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 37,154,026 bp
  • C to A, chromosome 1 at 46,139,678 bp
  • T to A, chromosome 1 at 97,645,890 bp
  • C to A, chromosome 1 at 155,687,004 bp
  • T to C, chromosome 1 at 157,472,355 bp
  • A to G, chromosome 2 at 32,778,207 bp
  • G to A, chromosome 2 at 65,682,083 bp
  • A to T, chromosome 2 at 76,706,751 bp
  • A to C, chromosome 2 at 84,351,231 bp
  • C to T, chromosome 2 at 91,167,508 bp
  • A to G, chromosome 2 at 121,342,658 bp
  • A to G, chromosome 3 at 51,247,648 bp
  • T to A, chromosome 3 at 69,575,241 bp
  • A to G, chromosome 3 at 94,346,189 bp
  • A to T, chromosome 3 at 121,228,392 bp
  • T to C, chromosome 3 at 122,961,267 bp
  • T to C, chromosome 4 at 130,774,477 bp
  • T to C, chromosome 5 at 77,309,830 bp
  • T to A, chromosome 5 at 98,737,708 bp
  • G to A, chromosome 5 at 103,541,058 bp
  • T to C, chromosome 5 at 107,545,801 bp
  • A to G, chromosome 5 at 136,743,098 bp
  • A to T, chromosome 5 at 137,796,770 bp
  • A to G, chromosome 5 at 140,882,000 bp
  • T to A, chromosome 6 at 67,724,940 bp
  • A to T, chromosome 7 at 43,979,787 bp
  • A to G, chromosome 7 at 46,154,436 bp
  • C to T, chromosome 7 at 68,745,176 bp
  • T to A, chromosome 7 at 80,304,372 bp
  • T to C, chromosome 7 at 132,270,522 bp
  • A to T, chromosome 7 at 135,704,604 bp
  • A to G, chromosome 8 at 25,748,536 bp
  • A to G, chromosome 8 at 72,196,804 bp
  • T to C, chromosome 8 at 122,480,994 bp
  • G to C, chromosome 9 at 8,656,704 bp
  • T to C, chromosome 9 at 32,322,221 bp
  • T to C, chromosome 9 at 63,145,046 bp
  • T to C, chromosome 10 at 67,231,995 bp
  • C to A, chromosome 10 at 80,005,033 bp
  • G to A, chromosome 11 at 32,371,533 bp
  • T to A, chromosome 11 at 59,760,855 bp
  • T to A, chromosome 11 at 60,464,175 bp
  • T to C, chromosome 11 at 72,317,532 bp
  • T to A, chromosome 11 at 83,512,408 bp
  • G to A, chromosome 11 at 87,533,602 bp
  • T to C, chromosome 12 at 98,688,842 bp
  • A to G, chromosome 12 at 115,802,790 bp
  • T to C, chromosome 13 at 13,825,272 bp
  • T to C, chromosome 13 at 55,499,106 bp
  • G to A, chromosome 13 at 56,537,163 bp
  • A to G, chromosome 13 at 96,879,100 bp
  • T to C, chromosome 14 at 53,704,451 bp
  • T to G, chromosome 14 at 103,200,185 bp
  • A to G, chromosome 14 at 120,929,639 bp
  • T to C, chromosome 14 at 121,242,406 bp
  • C to T, chromosome 16 at 59,329,243 bp
  • G to T, chromosome 16 at 91,638,784 bp
  • G to A, chromosome 16 at 96,643,922 bp
  • A to G, chromosome 16 at 97,812,592 bp
  • C to G, chromosome 17 at 24,398,504 bp
  • A to G, chromosome 17 at 25,780,398 bp
  • A to T, chromosome 17 at 25,850,749 bp
  • T to A, chromosome 17 at 85,452,438 bp
  • C to T, chromosome 18 at 37,709,426 bp
  • T to A, chromosome 19 at 25,603,328 bp
  • T to C, chromosome 19 at 43,803,670 bp
  • C to T, chromosome 19 at 47,615,229 bp
  • C to A, chromosome 19 at 50,144,032 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7911 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045960-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.