Strain Name:
C57BL/6J-MtgxR7938Btlr/Mmmh
Stock Number:
045984-MU
Citation ID:
RRID:MMRRC_045984-MU
Other Names:
R7938 (G1)
Major Collection:

Strain Information

Hapln1
Name: hyaluronan and proteoglycan link protein 1
Synonyms: LP-1, link protein, CLP, Crtl1, cartilage linking protein 1, Crtl1l
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 12950
VEGA: 13
HGNC: HGNC:2380
Homologene: 1420
Bmp7
Name: bone morphogenetic protein 7
Synonyms: OP1, osteogenic protein 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12162
HGNC: HGNC:1074
Homologene: 20410
Zfp423
Name: zinc finger protein 423
Synonyms: Zfp104, Ebfaz, Roaz, ataxia1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94187
Homologene: 9010
Rpa1
Name: replication protein A1
Synonyms: 5031405K23Rik, Rpa, RP-A, 70kDa, RF-A
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68275
Homologene: 2208
Katna1
Name: katanin p60 (ATPase-containing) subunit A1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 23924
HGNC: HGNC:6216
Homologene: 56014
Usp47
Name: ubiquitin specific peptidase 47
Synonyms: A630020C16Rik, 4930502N04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74996
Homologene: 9929
Myh10
Name: myosin, heavy polypeptide 10, non-muscle
Synonyms: Myhn2, Fltn, Fltn, NMHC II-B, 5730504C04Rik, nonmuscle myosin heavy chain IIB, 9330167F11Rik, myosin IIB, nonmuscle myosin heavy chain II-B, Myhn-2, SMemb, Myosin IIB, NMHC-B
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 77579
HGNC: HGNC:7568
Homologene: 55941
Orc4
Name: origin recognition complex, subunit 4
Synonyms: Orc4, Orc4l, Orc4P, mMmORC4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26428
HGNC: HGNC:8490
Homologene: 8059
Srebf2
Name: sterol regulatory element binding factor 2
Synonyms: SREBP2gc, lop13, SREBP2, SREBP-2, nuc, bHLHd2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20788
VEGA: 15
Homologene: 20966
Bcam
Name: basal cell adhesion molecule
Synonyms: B-CAM, Lu, 1200005K12Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57278
HGNC: HGNC:6722
Homologene: 21149
Sqle
Name: squalene epoxidase
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20775
Homologene: 2355
Coch
Name: cochlin
Synonyms: Coch-5B2, D12H14S564E
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 12810
VEGA: 12
HGNC: HGNC:2180
Homologene: 20868
Kcnip2
Name: Kv channel-interacting protein 2
Synonyms: KChIP2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 80906
Homologene: 23710
Casz1
Name: castor zinc finger 1
Synonyms: 2410019P08Rik, D4Ertd432e, Cst, castor
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69743
Homologene: 9824
Gpr12
Name: G-protein coupled receptor 12
Synonyms: Gpcr12, Gpcr20, Gpcr01
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14738
HGNC: HGNC:4466
Homologene: 3868
Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Synonyms: P450-1, cytochrome P450 subfamily I, polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13076
VEGA: 9
HGNC: HGNC:2595
Homologene: 68062
Ampd2
Name: adenosine monophosphate deaminase 2
Synonyms: 1200014F01Rik, Ampd-2, m4521Dajl
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109674
HGNC: HGNC:469
Homologene: 2979
Lyar
Name: Ly1 antibody reactive clone
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 17089
Homologene: 41200
Klf5
Name: Kruppel-like transcription factor 5
Synonyms: IKLF, 4930520J07Rik, CKLF, Bteb2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12224
VEGA: 14
HGNC: HGNC:6349
Homologene: 37520
Terf2ip
Name: telomeric repeat binding factor 2, interacting protein
Synonyms: Rap1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 57321
Homologene: 10357
Qser1
Name: glutamine and serine rich 1
Synonyms: 4732486I23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99003
Homologene: 11710
Trim37
Name: tripartite motif-containing 37
Synonyms: MUL, 1110032A10Rik, 2810004E07Rik, TEF3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68729
HGNC: HGNC:7523
Homologene: 9084
Nup153
Name: nucleoporin 153
Synonyms: B130015D15Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218210
HGNC: HGNC:8062
Homologene: 68442
Kel
Name: Kell blood group
Synonyms: CD238
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 23925
HGNC: HGNC:6308
Homologene: 362
Reln
Name: reelin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19699
HGNC: HGNC:9957
Homologene: 3699
Uggt2
Name: UDP-glucose glycoprotein glucosyltransferase 2
Synonyms: 3110001A05Rik, A230065J02Rik, Ugcgl2, 1810064L21Rik, 3110027P15Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66435
Homologene: 56875
Fat2
Name: FAT atypical cadherin 2
Synonyms: EMI2, Fath2, mKIAA0811, LOC245827
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: PC5/6A, PC6, b2b1549Clo, SPC6, PC5A, b2b585Clo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Dner
Name: delta/notch-like EGF repeat containing
Synonyms: A930026D19Rik, BET
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227325
Homologene: 26722
Prss46
Name: serine protease 46
Synonyms: 1700112C13Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74306
Homologene: 77706
Ppfia2
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
Synonyms: E130120L08Rik, Liprin-alpha2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 327814
VEGA: 10
HGNC: HGNC:9246
Homologene: 27953
Mrgprx2
Name: MAS-related GPR, member X2
Synonyms: MrgB10, Mrgprb10
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243978
Homologene: 24986
Trank1
Name: tetratricopeptide repeat and ankyrin repeat containing 1
Synonyms: LOC235639, C030048J01Rik, Lba1, A230061D21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320429
Homologene: 45845
Col6a6
Name: collagen, type VI, alpha 6
Synonyms: E330026B02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245026
Homologene: 18260
Tshz3
Name: teashirt zinc finger family member 3
Synonyms: A630038G13Rik, Tsh3, Zfp537, teashirt3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243931
Homologene: 10835
Iqcm
Name: IQ motif containing M
Synonyms: 1700007B14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71831
Homologene: 53050
Svs3b
Name: seminal vesicle secretory protein 3B
Synonyms: 9530004A22Rik, SVS III
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329557
Homologene: 110771
Ubxn8
Name: UBX domain protein 8
Synonyms: Rep-8, D0H8S2298E, Ubxd6, Rep8h
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 108159
Homologene: 4149
Ppp1r36
Name: protein phosphatase 1, regulatory subunit 36
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 210762
VEGA: 12
Homologene: 52094
Dgkz
Name: diacylglycerol kinase zeta
Synonyms: mDGK[z], E130307B02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 104418
HGNC: HGNC:2857
Homologene: 37831
Vmn2r52
Name: vomeronasal 2, receptor 52
Synonyms: EG384534
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 384534
Homologene: 129605
Mboat1
Name: membrane bound O-acyltransferase domain containing 1
Synonyms: 9130215M02Rik, Oact1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218121
Homologene: 57467
Or5h19
Name: olfactory receptor family 5 subfamily H member 19
Synonyms: Olfr187, MOR183-8, GA_x54KRFPKG5P-55265713-55264787
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258319
Homologene: 133069
Cnga1
Name: cyclic nucleotide gated channel alpha 1
Synonyms: Cncg
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12788
HGNC: HGNC:2148
Homologene: 55432
Nfasc
Name: neurofascin
Synonyms: D430023G06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269116
Homologene: 24945
Nup50l
Name: nucleoporin 50 like
Synonyms: 1700123L14Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78482
HGNC: HGNC:8065
Spata31f1a
Name: spermatogenesis associated 31 subfamily F member 1A
Synonyms: Gm12429, Fam205a1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433698
Homologene: 79022
Morn5
Name: MORN repeat containing 5
Synonyms: 1700010A17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75495
Homologene: 16510
Plscr4
Name: phospholipid scramblase 4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235527
Homologene: 23217
Cyp3a16
Name: cytochrome P450, family 3, subfamily a, polypeptide 16
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13114
HGNC: HGNC:2638
Homologene: 133568
Lax1
Name: lymphocyte transmembrane adaptor 1
Synonyms: E430019B13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240754
Homologene: 49504
Cfap61
Name: cilia and flagella associated protein 61
Synonyms: 4930529M08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 78774
Zw10
Name: zw10 kinetochore protein
Synonyms: 6330566F14Rik, MmZw10
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 26951
VEGA: 9
Homologene: 37959
Pif1
Name: PIF1 5'-to-3' DNA helicase
Synonyms: AI449441
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208084
Homologene: 99775
Tdrd9
Name: tudor domain containing 9
Synonyms: 4930441E05Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74691
Homologene: 14311
Rsph3a
Name: radial spoke 3A homolog (Chlamydomonas)
Synonyms: Rshl2, 4930524H12Rik, Rshl2a, 1700012G05Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66832
VEGA: 17
Homologene: 12043
Hlx
Name: H2.0-like homeobox
Synonyms: Hlx1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 15284
HGNC: HGNC:4978
Homologene: 7363
Or1o4
Name: olfactory receptor family 1 subfamily O member 4
Synonyms: Olfr99, MOR156-1, GA_x6K02T2PSCP-1720261-1719344
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258508
Homologene: 74030
Hace1
Name: HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
Synonyms: A730034A22Rik, 1700042J16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 209462
Homologene: 10807
Rimkla
Name: ribosomal modification protein rimK-like family member A
Synonyms: NAAGS-II, Rimk
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 194237
Homologene: 18336
Or4x6
Name: olfactory receptor family 4 subfamily X member 6
Synonyms: Olfr1269, GA_x6K02T2Q125-51551618-51550689, MOR228-3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258339
Homologene: 133727
Wdr81
Name: WD repeat domain 81
Synonyms: nur5, shakey 5, MGC32441
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192652
Homologene: 13983
Trav8-1
Name: T cell receptor alpha variable 8-1
Synonyms: Gm13950
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 674098
Ccdc59
Name: coiled-coil domain containing 59
Synonyms: 2300004H16Rik, D10Ertd718e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52713
Homologene: 32208
Trem2
Name: triggering receptor expressed on myeloid cells 2
Synonyms: Trem2c, Trem2a, Trem2b
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 83433
Homologene: 10352
Frmpd2
Name: FERM and PDZ domain containing 2
Synonyms: Gm626, LOC380890, ENSMUSG00000071536, LOC268729, Frmpd2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268729
Homologene: 51854
Gm45861
Name: predicted gene 45861
Type: Gene
Species: Mouse
Chromosome: 8
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 84,695,497 bp
  • A to G, chromosome 1 at 132,605,531 bp
  • A to T, chromosome 1 at 133,680,158 bp
  • T to G, chromosome 1 at 184,731,928 bp
  • A to T, chromosome 2 at 36,057,070 bp
  • A to T, chromosome 2 at 48,910,191 bp
  • A to T, chromosome 2 at 90,118,829 bp
  • G to T, chromosome 2 at 91,965,472 bp
  • A to C, chromosome 2 at 104,788,967 bp
  • A to G, chromosome 2 at 146,045,456 bp
  • A to T, chromosome 2 at 164,255,647 bp
  • A to C, chromosome 2 at 172,879,490 bp
  • C to A, chromosome 3 at 108,080,116 bp
  • A to G, chromosome 4 at 42,850,765 bp
  • A to G, chromosome 4 at 119,470,613 bp
  • G to A, chromosome 4 at 148,944,486 bp
  • A to C, chromosome 5 at 21,950,872 bp
  • A to G, chromosome 5 at 38,230,951 bp
  • T to C, chromosome 5 at 72,604,254 bp
  • T to A, chromosome 5 at 145,452,856 bp
  • T to A, chromosome 5 at 146,583,284 bp
  • G to T, chromosome 6 at 41,698,376 bp
  • T to C, chromosome 6 at 96,164,885 bp
  • T to C, chromosome 7 at 10,159,373 bp
  • T to G, chromosome 7 at 19,756,813 bp
  • T to C, chromosome 7 at 36,769,158 bp
  • T to C, chromosome 7 at 48,482,492 bp
  • T to A, chromosome 7 at 112,087,925 bp
  • T to A, chromosome 8 at 27,581,962 bp
  • A to G, chromosome 8 at 33,621,684 bp
  • G to T, chromosome 8 at 75,577,968 bp
  • T to C, chromosome 8 at 87,895,676 bp
  • T to C, chromosome 8 at 112,012,085 bp
  • T to A, chromosome 9 at 49,071,633 bp
  • T to G, chromosome 9 at 57,701,790 bp
  • A to G, chromosome 9 at 65,594,791 bp
  • C to T, chromosome 9 at 92,490,790 bp
  • A to C, chromosome 9 at 105,780,684 bp
  • A to G, chromosome 9 at 110,851,432 bp
  • A to G, chromosome 9 at 111,365,028 bp
  • G to T, chromosome 10 at 7,761,311 bp
  • C to T, chromosome 10 at 45,686,696 bp
  • T to A, chromosome 10 at 105,841,594 bp
  • A to G, chromosome 10 at 106,474,787 bp
  • T to C, chromosome 11 at 55,273,096 bp
  • T to A, chromosome 11 at 68,692,501 bp
  • CA to C, chromosome 11 at 75,307,224 bp
  • T to C, chromosome 11 at 75,448,002 bp
  • A to G, chromosome 11 at 87,147,037 bp
  • T to A, chromosome 12 at 51,596,583 bp
  • A to T, chromosome 12 at 76,438,406 bp
  • A to T, chromosome 12 at 112,031,215 bp
  • A to G, chromosome 13 at 30,231,976 bp
  • G to T, chromosome 13 at 46,689,379 bp
  • G to A, chromosome 13 at 89,605,228 bp
  • T to C, chromosome 14 at 33,538,289 bp
  • T to G, chromosome 14 at 53,470,231 bp
  • T to C, chromosome 14 at 99,299,008 bp
  • T to A, chromosome 14 at 119,059,107 bp
  • C to A, chromosome 15 at 59,324,466 bp
  • T to A, chromosome 15 at 82,172,815 bp
  • A to T, chromosome 16 at 59,035,962 bp
  • G to T, chromosome 17 at 7,946,218 bp
  • T to A, chromosome 17 at 37,280,100 bp
  • T to A, chromosome 17 at 48,351,749 bp
  • T to A, chromosome 19 at 17,466,185 bp
  • A to T, chromosome 19 at 45,794,290 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7938 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045984-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.