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Strain Name:
C57BL/6J-MtgxR8139Btlr/Mmmh
Stock Number:
067567-MU
Citation ID:
RRID:MMRRC_067567-MU
Other Names:
R8139 (G1)
Major Collection:

Strain Information

Kit
Name: KIT proto-oncogene receptor tyrosine kinase
Synonyms: Steel Factor Receptor, c-KIT, Dominant white spotting, belly-spot, Tr-kit, SOW3, SCO5, SCO1, Gsfsow3, Gsfsco5, Gsfsco1, CD117
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16590
HGNC: HGNC:6342
Homologene: 187
Vps33a
Name: VPS33A CORVET/HOPS core subunit
Synonyms: bf, 3830421M04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77573
Homologene: 11294
Cacna1h
Name: calcium channel, voltage-dependent, T type, alpha 1H subunit
Synonyms: alpha13.2, Cav3.2, T-type Cav3.2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 58226
HGNC: HGNC:1395
Homologene: 56913
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Tmed10
Name: transmembrane p24 trafficking protein 10
Synonyms: 1110014C03Rik, p24delta1, p23
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68581
VEGA: 12
Homologene: 4972
Xpnpep3
Name: X-prolyl aminopeptidase 3, mitochondrial
Synonyms: E430012M05Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 321003
Kif16b
Name: kinesin family member 16B
Synonyms: N-3 kinesin, 8430434E15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16558
Homologene: 135708
Srebf2
Name: sterol regulatory element binding factor 2
Synonyms: SREBP-2, nuc, SREBP2, SREBP2gc, bHLHd2, lop13
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20788
VEGA: 15
Homologene: 20966
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: trithorax Drosophila, HTRX1, ALL-1, All1, Cxxc7, Mll, Mll1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214162
HGNC: HGNC:7132
Homologene: 4338
Ndufa5
Name: NADH:ubiquinone oxidoreductase subunit A5
Synonyms: 2900002J19Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68202
HGNC: HGNC:7688
Homologene: 3664
Cnn3
Name: calponin 3, acidic
Synonyms: 1600014M03Rik, Calpo3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71994
HGNC: HGNC:2157
Homologene: 37533
Eftud2
Name: elongation factor Tu GTP binding domain containing 2
Synonyms: U5-116kD, 116kDa, Snrp116
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20624
Homologene: 3133
Vars1
Name: valyl-tRNA synthetase 1
Synonyms: G7a, D17H6S56E, Bat-6, Bat6, Vars2, Vars
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22321
Homologene: 4587
Pgr
Name: progesterone receptor
Synonyms: NR3C3, PR, 9930019P03Rik, PR-B, PR-A, ENSMUSG00000074510
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18667
HGNC: HGNC:8910
Homologene: 713
Lyl1
Name: lymphoblastomic leukemia 1
Synonyms: Lyl-1, bHLHa18
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17095
VEGA: 8
HGNC: HGNC:6734
Homologene: 4078
Ppfia1
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
Synonyms: liprin, C030014K08Rik, Liprin-alpha1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233977
HGNC: HGNC:9245
Homologene: 20802
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 1810042B05Rik, Coh1, C330002D13Rik, 2310042E16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Fbxl5
Name: F-box and leucine-rich repeat protein 5
Synonyms: Fir4, Fbl4
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 242960
Homologene: 8129
Mtx2
Name: metaxin 2
Synonyms: 1500012G02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 53375
HGNC: HGNC:7506
Homologene: 4777
Pcnx3
Name: pecanex homolog 3
Synonyms: Pcnxl3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 104401
Homologene: 17000
Elac2
Name: elaC ribonuclease Z 2
Synonyms: 1110017O07Rik, D11Wsu80e, tRNase Z(L)
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68626
Homologene: 6403
Timm21
Name: translocase of inner mitochondrial membrane 21
Synonyms: 2700002I20Rik, 1700034H14Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67105
VEGA: 18
Homologene: 32211
Slc25a36
Name: solute carrier family 25, member 36
Synonyms: C330005L02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 192287
Homologene: 10039
Thumpd1
Name: THUMP domain containing 1
Synonyms: 6330575P11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233802
Homologene: 5878
Fam13b
Name: family with sequence similarity 13, member B
Synonyms: 2610024E20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225358
VEGA: 18
HGNC: HGNC:1335
Homologene: 9585
Tmem108
Name: transmembrane protein 108
Synonyms: B130017P16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 81907
Homologene: 18688
Kcng3
Name: potassium voltage-gated channel, subfamily G, member 3
Synonyms: KV6.3, Kv10.1b, Kv10.1a
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 225030
VEGA: 17
Homologene: 15168
Fhdc1
Name: FH2 domain containing 1
Synonyms: 6330505N24Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229474
Homologene: 18920
Cdc42bpa
Name: CDC42 binding protein kinase alpha
Synonyms: DMPK-like, A930014J19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226751
HGNC: HGNC:1737
Homologene: 55765
Loxhd1
Name: lipoxygenase homology domains 1
Synonyms: 1700096C21Rik, sba
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240411
Slco1a6
Name: solute carrier organic anion transporter family, member 1a6
Synonyms: organic anion-transporting polypeptide, Oatp-5, 4930422F19Rik, Slc21a13
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 28254
Homologene: 23416
Dnah14
Name: dynein, axonemal, heavy chain 14
Synonyms: LOC381311, A230079K17Rik, Gm980, Dnahc14
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240960
HGNC: HGNC:2945
Homologene: 90078
Or7g20
Name: olfactory receptor family 7 subfamily G member 20
Synonyms: GA_x6K02T2PVTD-12771995-12772930, MOR150-3, Olfr835
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 257872
HGNC: HGNC:8466
Homologene: 133702
Degs1l
Name: delta 4-desaturase, sphingolipid 1 like
Synonyms: 9130409I23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 619326
Homologene: 134522
Ogfod2
Name: 2-oxoglutarate and iron-dependent oxygenase domain containing 2
Synonyms: 1300006G11Rik, 5730405M13Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 66627
Homologene: 32588
Irs1
Name: insulin receptor substrate 1
Synonyms: IRS-1, G972R
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16367
HGNC: HGNC:6125
Homologene: 4049
Ppfia4
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
Synonyms: 1110008G13Rik, LOC100042382, Liprin-alpha4, Gm3812
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68507
HGNC: HGNC:9248
Homologene: 66200
Abca6
Name: ATP-binding cassette, sub-family A member 6
Synonyms: 6330565N06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76184
HGNC: HGNC:36
Homologene: 71264
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: D3Bwg1078e, 4732458A06Rik, D130016K21Rik, 9430063L05Rik, Usmg4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 83679
Homologene: 66961
Snx15
Name: sorting nexin 15
Synonyms: E130013C21Rik, 1500032B08Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 69024
Homologene: 12294
Nrxn3
Name: neurexin III
Synonyms: neurexin III beta, neurexin III alpha, neurexin III beta, neurexin III alpha, 9330112C09Rik, D12Bwg0831e, 4933401A11Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18191
HGNC: HGNC:8010
Homologene: 83225
Col11a1
Name: collagen, type XI, alpha 1
Synonyms: C530001D20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12814
HGNC: HGNC:2186
Homologene: 56389
Vsig10l
Name: V-set and immunoglobulin domain containing 10 like
Synonyms: 2210412E05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75690
Homologene: 35386
I830077J02Rik
Name: RIKEN cDNA I830077J02 gene
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 433638
Homologene: 45482
Notch4
Name: notch 4
Synonyms: Int-3, Int3, N4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18132
HGNC: HGNC:7884
Homologene: 3351
Zfp467
Name: zinc finger protein 467
Synonyms: MNCb-3350, EZI, 1190001I08Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68910
Homologene: 10758
Vmn2r54
Name: vomeronasal 2, receptor 54
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 666085
Homologene: 104040
Oosp1
Name: oocyte secreted protein 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 170834
Homologene: 87189
Zfp438
Name: zinc finger protein 438
Synonyms: 9430091M14Rik, B830013J05Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240186
VEGA: 18
Homologene: 18695
Kptn
Name: kaptin
Synonyms: 2E4, actin-binding protein, 2310042D10Rik, C030013F01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70394
HGNC: HGNC:6404
Homologene: 5127
Irag1
Name: inositol 1,4,5-triphosphate receptor associated 1
Synonyms: Ris1, Mrvi1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17540
HGNC: HGNC:7237
Homologene: 4425
Inf2
Name: inverted formin, FH2 and WH2 domain containing
Synonyms: EG629699, 2610204M08Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 70435
VEGA: 12
Homologene: 82406
Slc5a11
Name: solute carrier family 5 (sodium/glucose cotransporter), member 11
Synonyms: 2010013B02Rik, Kst1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233836
Homologene: 14184
Or7g28
Name: olfactory receptor family 7 subfamily G member 28
Synonyms: GA_x6K02T2PVTD-13098546-13097608, MOR149-3, Olfr846
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258279
Oxnad1
Name: oxidoreductase NAD-binding domain containing 1
Synonyms: 2410002F01Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218885
Homologene: 16303
Best3
Name: bestrophin 3
Synonyms: mBest4, Vmd2l3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 382427
VEGA: 10
Homologene: 33850
Dus3l
Name: dihydrouridine synthase 3 like
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224907
VEGA: 17
Homologene: 6533
Or4c115
Name: olfactory receptor family 4 subfamily C member 115
Synonyms: GA_x6K02T2Q125-50579531-50578596, MOR233-5, Olfr1220
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258902
Homologene: 74242
Mmp24
Name: matrix metallopeptidase 24
Synonyms: MT5-MMP, Membrane type 5-MMP
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17391
HGNC: HGNC:7172
Homologene: 21331
4930567H17Rik
Name: RIKEN cDNA 4930567H17 gene
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 619303
Homologene: 134521
Ptgdr
Name: prostaglandin D receptor
Synonyms: DP
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19214
HGNC: HGNC:9591
Homologene: 736
Ccdc113
Name: coiled-coil domain containing 113
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244608
Homologene: 40927
Tram1l1
Name: translocation associated membrane protein 1-like 1
Synonyms: A830091N21Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229801
Homologene: 17142
Rhbdd2
Name: rhomboid domain containing 2
Synonyms: 0610011L13Rik, Rhbdl7, Usmg1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 215160
Homologene: 32481
Rhobtb1
Name: Rho-related BTB domain containing 1
Synonyms: 1700008H16Rik, 3110048G13Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 69288
Homologene: 8892
Tspan8
Name: tetraspanin 8
Synonyms: E330007O21Rik, Tm4sf3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216350
VEGA: 10
Homologene: 20968
Gtf3c6
Name: general transcription factor IIIC, polypeptide 6, alpha
Synonyms: 2410016F19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67371
VEGA: 10
Homologene: 12121
Aamdc
Name: adipogenesis associated Mth938 domain containing
Synonyms: 1810037D19Rik, 1810020D17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66273
Homologene: 11658
Pcdha5
Name: protocadherin alpha 5
Synonyms: Cnr6, Crnr6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12941
HGNC: HGNC:8671
Homologene: 49565
Or5p67
Name: olfactory receptor family 5 subfamily P member 67
Synonyms: GA_x6K02T2PBJ9-10653693-10652749, MOR204-18, Olfr492
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258490
Homologene: 133673
Vamp9
Name: vesicle-associated membrane protein 9
Synonyms: Gm35911
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 102639650
VEGA: 5
Homologene: 140982
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 34,191,852 bp
  • A to T, chromosome 1 at 82,289,739 bp
  • A to G, chromosome 1 at 134,300,528 bp
  • A to T, chromosome 1 at 180,069,319 bp
  • A to G, chromosome 1 at 181,054,793 bp
  • G to T, chromosome 1 at 181,755,288 bp
  • G to A, chromosome 2 at 74,876,370 bp
  • A to G, chromosome 2 at 89,097,843 bp
  • A to C, chromosome 2 at 142,901,365 bp
  • C to T, chromosome 2 at 155,814,045 bp
  • A to G, chromosome 3 at 84,451,483 bp
  • G to T, chromosome 3 at 97,696,993 bp
  • A to G, chromosome 3 at 105,927,998 bp
  • A to G, chromosome 3 at 114,097,049 bp
  • G to T, chromosome 3 at 121,455,069 bp
  • A to G, chromosome 3 at 124,321,787 bp
  • G to A, chromosome 5 at 43,758,745 bp
  • T to C, chromosome 5 at 75,652,805 bp
  • A to G, chromosome 5 at 99,924,926 bp
  • T to C, chromosome 5 at 123,533,952 bp
  • C to T, chromosome 5 at 124,113,475 bp
  • T to A, chromosome 5 at 135,636,335 bp
  • A to T, chromosome 6 at 24,522,758 bp
  • C to T, chromosome 6 at 48,439,334 bp
  • T to C, chromosome 6 at 142,089,900 bp
  • G to T, chromosome 7 at 12,615,816 bp
  • T to C, chromosome 7 at 16,123,976 bp
  • T to C, chromosome 7 at 43,463,729 bp
  • T to C, chromosome 7 at 97,565,243 bp
  • T to A, chromosome 7 at 108,322,906 bp
  • A to G, chromosome 7 at 110,899,672 bp
  • T to C, chromosome 7 at 119,720,585 bp
  • A to G, chromosome 7 at 123,269,976 bp
  • T to C, chromosome 7 at 142,438,268 bp
  • A to G, chromosome 7 at 144,520,693 bp
  • A to T, chromosome 8 at 84,702,847 bp
  • T to A, chromosome 8 at 95,558,738 bp
  • A to T, chromosome 9 at 8,956,340 bp
  • A to T, chromosome 9 at 19,035,575 bp
  • A to C, chromosome 9 at 19,361,208 bp
  • A to T, chromosome 9 at 44,819,290 bp
  • A to T, chromosome 9 at 97,080,452 bp
  • T to A, chromosome 9 at 103,499,885 bp
  • T to C, chromosome 10 at 40,257,473 bp
  • C to A, chromosome 10 at 69,266,290 bp
  • A to G, chromosome 10 at 115,839,897 bp
  • G to A, chromosome 10 at 117,004,426 bp
  • T to C, chromosome 11 at 64,980,614 bp
  • A to G, chromosome 11 at 102,867,859 bp
  • T to A, chromosome 11 at 110,184,133 bp
  • A to G, chromosome 12 at 85,344,317 bp
  • A to G, chromosome 12 at 90,204,664 bp
  • G to T, chromosome 12 at 112,601,640 bp
  • C to A, chromosome 14 at 32,092,091 bp
  • T to C, chromosome 14 at 44,858,685 bp
  • T to A, chromosome 15 at 35,607,272 bp
  • T to C, chromosome 15 at 76,174,310 bp
  • T to A, chromosome 15 at 81,448,459 bp
  • C to T, chromosome 15 at 82,178,765 bp
  • A to T, chromosome 17 at 25,383,723 bp
  • G to T, chromosome 17 at 34,584,800 bp
  • T to C, chromosome 17 at 35,011,504 bp
  • C to T, chromosome 17 at 56,767,058 bp
  • C to A, chromosome 17 at 83,631,087 bp
  • T to C, chromosome 18 at 5,214,013 bp
  • A to G, chromosome 18 at 34,473,633 bp
  • A to G, chromosome 18 at 36,962,738 bp
  • G to A, chromosome 18 at 77,380,496 bp
  • T to C, chromosome 18 at 84,951,138 bp
  • A to T, chromosome 19 at 5,665,745 bp
  • T to G, chromosome 19 at 6,119,915 bp
  • T to C, chromosome 19 at 6,119,916 bp
  • T to C, chromosome 19 at 11,667,754 bp
  • G to T, chromosome X at 70,394,514 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8139 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
067567-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.