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Strain Name:
C57BL/6J-MtgxR8190Btlr/Mmmh
Stock Number:
067613-MU
Citation ID:
RRID:MMRRC_067613-MU
Other Names:
R8190 (G1)
Major Collection:

Strain Information

Sufu
Name: SUFU negative regulator of hedgehog signaling
Synonyms: Su(Fu), 2810026F04Rik, b2b273Clo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 24069
Homologene: 9262
Htr4
Name: 5 hydroxytryptamine (serotonin) receptor 4
Synonyms: 5-HT4L, 5-HT4
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 15562
VEGA: 18
HGNC: HGNC:5299
Homologene: 20243
Gsta4
Name: glutathione S-transferase, alpha 4
Synonyms: GST 5.7, mGsta4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14860
VEGA: 9
Homologene: 135605
Ptpa
Name: protein phosphatase 2 protein activator
Synonyms: 2610042B21Rik, Ppp2r4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 110854
HGNC: HGNC:9308
Homologene: 6149
Mfn1
Name: mitofusin 1
Synonyms: 6330416C07Rik, 2310002F04Rik, D3Ertd265e, HR2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67414
Homologene: 11481
Slc1a6
Name: solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
Synonyms: EAAT4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20513
VEGA: 10
Homologene: 21055
Zfp113
Name: zinc finger protein 113
Synonyms: 4732456B05Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56314
Homologene: 50027
Rbp1
Name: retinol binding protein 1, cellular
Synonyms: Crbp, Rbp-1, CRBPI
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19659
HGNC: HGNC:9919
Homologene: 2175
Anks1
Name: ankyrin repeat and SAM domain containing 1
Synonyms: Odin
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224650
Homologene: 9068
Smarcc1
Name: SWI/SNF related BAF chromatin remodeling complex subunit C1
Synonyms: BAF155, SRG3, msp3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20588
Homologene: 68296
Ambra1
Name: autophagy/beclin 1 regulator 1
Synonyms: 2310079H06Rik, D030051N19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228361
Homologene: 18204
Pds5a
Name: PDS5 cohesin associated factor A
Synonyms: E230024D05Rik, 9030416H16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71521
Homologene: 22877
Exosc5
Name: exosome component 5
Synonyms: D7Wsu180e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 27998
Homologene: 5981
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: D130015N03Rik, 2810449H11Rik, tbl
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Actr8
Name: ARP8 actin-related protein 8
Synonyms: ARP8, 5730542K05Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56249
VEGA: 14
Homologene: 11286
Frs2
Name: fibroblast growth factor receptor substrate 2
Synonyms: SNT1, C330018A15Rik, Frs2alpha
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 327826
VEGA: 10
Homologene: 4846
Clock
Name: clock circadian regulator
Synonyms: 5330400M04Rik, KAT13D, bHLHe8
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12753
HGNC: HGNC:2082
Homologene: 3603
Vps8
Name: VPS8 CORVET complex subunit
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 209018
Homologene: 44592
Gprin3
Name: GPRIN family member 3
Synonyms: C030038J10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243385
Homologene: 52334
Hipk2
Name: homeodomain interacting protein kinase 2
Synonyms: Stank, 1110014O20Rik, B230339E18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 15258
Homologene: 68766
Iqgap3
Name: IQ motif containing GTPase activating protein 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 404710
Homologene: 26400
Bbs9
Name: Bardet-Biedl syndrome 9
Synonyms: EST 3159894, E130103I17Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 319845
Homologene: 44480
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230895
Homologene: 15583
Lpin1
Name: lipin 1
Synonyms: Lipin1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 14245
VEGA: 12
Homologene: 9266
Cpne6
Name: copine VI
Synonyms: neuronal copine
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12891
HGNC: HGNC:2319
Homologene: 81815
Nbeal2
Name: neurobeachin-like 2
Synonyms: 1110014F23Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235627
Homologene: 86422
Deaf1
Name: DEAF1, transcription factor
Synonyms: C230009B13Rik, NUDR, suppressin
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 54006
Homologene: 9647
Zfyve26
Name: zinc finger, FYVE domain containing 26
Synonyms: 9330197E15Rik, LOC380767, A630028O16Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 211978
VEGA: 12
Homologene: 9102
Eif3j1
Name: eukaryotic translation initiation factor 3, subunit J1
Synonyms: 2700079K05Rik, 1810016I04Rik, eIF3-alpha, eIF3-p35, Eif3s1, Eif3j
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 78655
HGNC: HGNC:3270
Homologene: 37845
Fbxo34
Name: F-box protein 34
Synonyms: 5830426G16Rik, 2900057B08Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 78938
VEGA: 14
Homologene: 12713
Arhgap44
Name: Rho GTPase activating protein 44
Synonyms: AU040829
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216831
Homologene: 65284
Uxs1
Name: UDP-glucuronate decarboxylase 1
Synonyms: 1600025I13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67883
Homologene: 41609
Pak6
Name: p21 (RAC1) activated kinase 6
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 214230
Homologene: 23200
Ano4
Name: anoctamin 4
Synonyms: A330096O15Rik, Tmem16d
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 320091
Homologene: 66599
Celsr1
Name: cadherin, EGF LAG seven-pass G-type receptor 1
Synonyms: Scy, Crsh, crash, Adgrc1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12614
VEGA: 15
HGNC: HGNC:1850
Homologene: 7665
Eps8l1
Name: EPS8-like 1
Synonyms: 4632407K17Rik, EPS8R1, DRC3, 2310051G19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67425
Homologene: 15767
Nalcn
Name: sodium leak channel, non-selective
Synonyms: A530023G15Rik, Vgcnl1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 338370
VEGA: 14
Homologene: 21832
Agfg2
Name: ArfGAP with FG repeats 2
Synonyms: A630095P14Rik, Hrbl
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231801
HGNC: HGNC:5177
Homologene: 4430
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22635
Homologene: 124417
Synm
Name: synemin, intermediate filament protein
Synonyms: 4930412K21Rik, Synemin, Dmn
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233335
Homologene: 9081
Hrg
Name: histidine-rich glycoprotein
Synonyms: D18020, D16JH2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 94175
HGNC: HGNC:5181
Homologene: 137650
Nlrp4b
Name: NLR family, pyrin domain containing 4B
Synonyms: Nalp-gamma, Nalp4b
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210045
Homologene: 65242
Ahnak
Name: AHNAK nucleoprotein
Synonyms: DY6, 2310047C17Rik, 1110004P15Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Fndc8
Name: fibronectin type III domain containing 8
Synonyms: 4930466G16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 78919
Homologene: 9716
Cerkl
Name: ceramide kinase-like
Synonyms: Rp26
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228094
Homologene: 52396
Vil1
Name: villin 1
Synonyms: Villin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22349
Homologene: 5169
Ankrd24
Name: ankyrin repeat domain 24
Synonyms: 5730519E19Rik, 4631433D01Rik, D10Bur2e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70615
Homologene: 49885
Or52a5
Name: olfactory receptor family 52 subfamily A member 5
Synonyms: 3'[b]2, MOR22-3, GA_x6K02T2PBJ9-6504436-6503489, Olfr68
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18369
Homologene: 130658
Or5p63
Name: olfactory receptor family 5 subfamily P member 63
Synonyms: GA_x6K02T2PBJ9-10541702-10540758, MOR204-31P, MOR204-31P, MOR204-29P, Olfr1538-ps1, Olfr487
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258042
Homologene: 110483
Impa1
Name: inositol (myo)-1(or 4)-monophosphatase 1
Synonyms: lithium-sensitive myo-inositol monophosphatase A1, 2610002K09Rik, 2900059K10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 55980
HGNC: HGNC:6050
Homologene: 4043
Pabpc2
Name: poly(A) binding protein, cytoplasmic 2
Synonyms: Pabp2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 18459
Homologene: 56509
Tmc8
Name: transmembrane channel-like gene family 8
Synonyms: EVIN2, Ever2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217356
Homologene: 45126
Adcy7
Name: adenylate cyclase 7
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11513
HGNC: HGNC:238
Homologene: 866
Tgm1
Name: transglutaminase 1, K polypeptide
Synonyms: protein-glutamine-gamma-glutamyltransferase, K polypeptide, TG K, TGase 1, 2310004J08Rik, TGase1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21816
VEGA: 14
Homologene: 306
Lrrc38
Name: leucine rich repeat containing 38
Synonyms: A230053A07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242735
Homologene: 77949
Kcnh8
Name: potassium voltage-gated channel, subfamily H (eag-related), member 8
Synonyms: Kv12.1, ELK1, C130090D05Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 211468
Homologene: 14332
Fbln5
Name: fibulin 5
Synonyms: EVEC
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 23876
VEGA: 12
HGNC: HGNC:3602
Homologene: 38170
Plin1
Name: perilipin 1
Synonyms: 6030432J05Rik, perilipin B, perilipin A, Peri, Plin
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 103968
HGNC: HGNC:9076
Homologene: 2001
Zfp62
Name: zinc finger protein 62
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22720
Homologene: 40686
Dnajb8
Name: DnaJ heat shock protein family (Hsp40) member B8
Synonyms: mDj6, 1700016F14Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56691
Homologene: 23184
Vmn1r174
Name: vomeronasal 1 receptor 174
Synonyms: V1rd22
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404291
Homologene: 79577
Rgs7bp
Name: regulator of G-protein signalling 7 binding protein
Synonyms: A930030I01Rik, R7bp, D13Bwg1146e
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 52882
VEGA: 13
Homologene: 78705
Or4q3
Name: olfactory receptor family 4 subfamily Q member 3
Synonyms: GA_x6K02T2PMLR-6042130-6041183, MOR243-1, Olfr735
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 257909
Homologene: 71977
Arl6ip4
Name: ADP-ribosylation factor-like 6 interacting protein 4
Synonyms: Aip-4, Srp25
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 65105
Homologene: 9606
Adgra1
Name: adhesion G protein-coupled receptor A1
Synonyms: 2900059M17Rik, D7Ertd680e, Gpr123
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 52389
Homologene: 18582
Bmp4
Name: bone morphogenetic protein 4
Synonyms: Bmp2b, Bmp2b1, Bmp2b-1, Bmp-4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12159
HGNC: HGNC:1071
Homologene: 7247
Apol7e
Name: apolipoprotein L 7e
Synonyms: ENSMUSG00000071716
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 666348
VEGA: 15
HGNC: HGNC:619
Homologene: 40940
Gadd45a
Name: growth arrest and DNA-damage-inducible 45 alpha
Synonyms: Ddit1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13197
HGNC: HGNC:4095
Homologene: 1449
Or3a4
Name: olfactory receptor family 3 subfamily A member 4
Synonyms: GA_x6K02T2P1NL-4211516-4210581, MOR255-1, Olfr399
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 259006
Homologene: 27325
Yipf4
Name: Yip1 domain family, member 4
Synonyms: 2310034L04Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67864
VEGA: 17
Homologene: 32658
Fabp2
Name: fatty acid binding protein 2, intestinal
Synonyms: Fabpi, I-FABP, Fabpi
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14079
HGNC: HGNC:3556
Homologene: 107
Fam179b
Name:
Type: Gene
Species: Mouse
Chromosome: 12
Cfap99
Name: cilia and flagella associated protein 99
Synonyms: Gm21446
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100862066
Homologene: 82544
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 43,771,751 bp
  • G to T, chromosome 1 at 74,434,893 bp
  • G to A, chromosome 2 at 30,438,339 bp
  • T to A, chromosome 2 at 79,333,557 bp
  • C to T, chromosome 2 at 91,772,352 bp
  • C to T, chromosome 2 at 118,690,097 bp
  • A to T, chromosome 2 at 122,047,488 bp
  • A to G, chromosome 3 at 10,321,628 bp
  • A to T, chromosome 3 at 32,568,389 bp
  • A to T, chromosome 3 at 88,090,779 bp
  • A to T, chromosome 3 at 122,896,770 bp
  • G to A, chromosome 4 at 143,350,733 bp
  • T to G, chromosome 4 at 143,571,960 bp
  • T to A, chromosome 4 at 145,152,751 bp
  • A to T, chromosome 5 at 34,325,158 bp
  • A to T, chromosome 5 at 65,623,998 bp
  • A to T, chromosome 5 at 76,227,204 bp
  • A to C, chromosome 5 at 124,117,032 bp
  • T to A, chromosome 5 at 137,467,084 bp
  • T to A, chromosome 5 at 137,655,402 bp
  • G to T, chromosome 5 at 138,144,996 bp
  • A to T, chromosome 6 at 38,818,793 bp
  • A to G, chromosome 6 at 59,354,471 bp
  • A to G, chromosome 6 at 67,036,829 bp
  • C to T, chromosome 6 at 88,222,958 bp
  • C to A, chromosome 7 at 4,471,298 bp
  • A to G, chromosome 7 at 10,714,392 bp
  • T to C, chromosome 7 at 23,754,143 bp
  • T to C, chromosome 7 at 25,666,344 bp
  • A to T, chromosome 7 at 67,733,906 bp
  • A to G, chromosome 7 at 79,723,280 bp
  • A to T, chromosome 7 at 103,777,595 bp
  • A to G, chromosome 7 at 108,211,807 bp
  • G to T, chromosome 7 at 139,876,118 bp
  • T to C, chromosome 7 at 141,314,411 bp
  • A to G, chromosome 8 at 88,311,038 bp
  • T to C, chromosome 9 at 22,678,988 bp
  • T to A, chromosome 9 at 66,418,451 bp
  • T to C, chromosome 9 at 78,198,372 bp
  • T to G, chromosome 9 at 98,444,656 bp
  • T to A, chromosome 9 at 110,202,534 bp
  • C to T, chromosome 9 at 110,626,090 bp
  • A to G, chromosome 10 at 78,791,233 bp
  • T to A, chromosome 10 at 81,638,318 bp
  • C to T, chromosome 10 at 88,972,745 bp
  • C to T, chromosome 10 at 117,074,879 bp
  • A to G, chromosome 11 at 49,216,075 bp
  • C to A, chromosome 11 at 65,038,653 bp
  • T to A, chromosome 11 at 74,054,479 bp
  • T to G, chromosome 11 at 82,897,860 bp
  • T to G, chromosome 11 at 117,791,360 bp
  • T to C, chromosome 12 at 16,549,002 bp
  • T to C, chromosome 12 at 65,006,912 bp
  • T to C, chromosome 12 at 79,280,836 bp
  • T to A, chromosome 12 at 101,757,296 bp
  • T to C, chromosome 13 at 105,053,109 bp
  • T to C, chromosome 14 at 29,984,073 bp
  • T to A, chromosome 14 at 46,384,515 bp
  • C to A, chromosome 14 at 47,530,422 bp
  • A to T, chromosome 14 at 50,345,722 bp
  • T to C, chromosome 14 at 55,512,028 bp
  • C to T, chromosome 14 at 55,704,884 bp
  • T to A, chromosome 14 at 123,599,939 bp
  • A to T, chromosome 15 at 77,717,807 bp
  • A to G, chromosome 15 at 85,902,889 bp
  • A to T, chromosome 16 at 21,575,030 bp
  • A to T, chromosome 16 at 22,961,043 bp
  • C to T, chromosome 17 at 27,986,804 bp
  • C to T, chromosome 17 at 52,956,908 bp
  • G to T, chromosome 17 at 74,493,972 bp
  • G to A, chromosome 18 at 39,775,467 bp
  • A to G, chromosome 18 at 62,437,900 bp
  • G to A, chromosome 19 at 9,002,255 bp
  • G to T, chromosome 19 at 46,401,197 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8190 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
067613-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.