Strain Name:
C57BL/6J-MtgxR8413Btlr/Mmmh
Stock Number:
067767-MU
Citation ID:
RRID:MMRRC_067767-MU
Other Names:
R8413 (G1)
Major Collection:

Strain Information

Rgs3
Name: regulator of G-protein signaling 3
Synonyms: RGS3S, C2PA-RGS3, PDZ-RGS3, C2pa, 4930506N09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 50780
HGNC: HGNC:9999
Homologene: 32440
Gcn1
Name: GCN1 activator of EIF2AK4
Synonyms: G431004K08Rik, GCN1L, Gcn1l1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231659
HGNC: HGNC:4199
Homologene: 5887
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: D630005A10Rik, apollon, A430032G04Rik, A430040A19Rik, Bruce
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12211
Homologene: 7248
Srrt
Name: serrate RNA effector molecule homolog (Arabidopsis)
Synonyms: Ars2, Asr2, 2810019G02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 83701
Homologene: 9298
Phf24
Name: PHD finger protein 24
Synonyms: N28178, GINIP
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230085
Homologene: 18208
Gpc6
Name: glypican 6
Synonyms: 6720429C22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 23888
HGNC: HGNC:4454
Homologene: 55922
Tnks1bp1
Name: tankyrase 1 binding protein 1
Synonyms: TAB182
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228140
Homologene: 14117
Abca16
Name: ATP-binding cassette, sub-family A member 16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233810
Homologene: 132942
Itpr3
Name: inositol 1,4,5-triphosphate receptor 3
Synonyms: Ip3r3, Itpr-3, tf
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16440
HGNC: HGNC:6182
Homologene: 1675
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94109
Homologene: 69536
Ebf1
Name: early B cell factor 1
Synonyms: Olf1, O/E-1, Olf-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13591
HGNC: HGNC:3126
Homologene: 7297
Ttll5
Name: tubulin tyrosine ligase-like family, member 5
Synonyms: STAMP, 4930556H18Rik, 2310009M18Rik, 1700048H13Rik, D630041K24Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320244
Homologene: 9013
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225997
VEGA: 19
Homologene: 9767
Or2t6
Name: olfactory receptor family 2 subfamily T member 6
Synonyms: Olfr720, GA_x6K02T2PLTE-6544896-6543946, MOR274-2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258387
Homologene: 74036
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244484
Homologene: 12460
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329628
Homologene: 14377
Gm11639
Name: predicted gene 11639
Synonyms: Gm11639, Efcab15
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 105242472
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242627
Homologene: 135888
Vmn1r179
Name: vomeronasal 1 receptor 179
Synonyms: V1rd17
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404286
Homologene: 134022
Plcb2
Name: phospholipase C, beta 2
Synonyms: B230205M18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18796
HGNC: HGNC:9055
Homologene: 20957
Kcnh4
Name: potassium voltage-gated channel, subfamily H (eag-related), member 4
Synonyms: BEC2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380728
HGNC: HGNC:6253
Homologene: 8180
Eln
Name: elastin
Synonyms: tropoelastin, E030024M20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13717
HGNC: HGNC:3327
Henmt1
Name: HEN1 methyltransferase homolog 1 (Arabidopsis)
Synonyms: Hen1, 4921515J06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66715
Homologene: 32638
Slc8a3
Name: solute carrier family 8 (sodium/calcium exchanger), member 3
Synonyms: Ncx3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 110893
Homologene: 62645
Cfap65
Name: cilia and flagella associated protein 65
Synonyms: B230363K08Rik, Ccdc108
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241116
Homologene: 28093
Or12k5
Name: olfactory receptor family 12 subfamily K member 5
Synonyms: MOR159-4, Olfr358, GA_x6K02T2NLDC-33697309-33696317
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227789
Homologene: 74157
Tmem30a
Name: transmembrane protein 30A
Synonyms: D9Wsu20e, 2010200I23Rik, Cdc50a
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69981
Homologene: 110703
Mybpc2
Name: myosin binding protein C, fast-type
Synonyms: Fast-type C-protein
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233199
HGNC: HGNC:7550
Homologene: 3331
Naalad2
Name: N-acetylated alpha-linked acidic dipeptidase 2
Synonyms: NAALADASE2, GCPIII, D9Ertd285e, GCP3, NAADALASE2, Folh1b
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72560
Homologene: 3294
Or8g30
Name: olfactory receptor family 8 subfamily G member 30
Synonyms: MOR171-45, Olfr948, MOR171-51, GA_x6K02T2PVTD-33016899-33015934
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 257912
VEGA: 9
HGNC: HGNC:8484
Homologene: 79377
Nme8
Name: NME/NM23 family member 8
Synonyms: 1700056P15Rik, Txndc3, Sptrx-2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 73412
Homologene: 9593
Cdh26
Name: cadherin-like 26
Synonyms: LOC381409
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381409
Homologene: 18643
Arhgap31
Name: Rho GTPase activating protein 31
Synonyms: CdGAP
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12549
Homologene: 10644
Or4c104
Name: olfactory receptor family 4 subfamily C member 104
Synonyms: GA_x6K02T2Q125-50231574-50230642, MOR230-8, Olfr1199
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258450
Homologene: 128092
Adamts5
Name: ADAM metallopeptidase with thrombospondin type 1 motif 5
Synonyms: 9530092O11Rik, ADAM-TS5
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 23794
VEGA: 16
HGNC: HGNC:221
Homologene: 5109
Or4k15
Name: olfactory receptor family 4 subfamily K member 15
Synonyms: MOR246-2, Olfr727, GA_x6K02T2PMLR-5817082-5818056
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258316
Homologene: 84571
Prss33
Name: serine protease 33
Synonyms: tryptase-6, mT6, Eos
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 353130
Homologene: 77185
Zeb2
Name: zinc finger E-box binding homeobox 2
Synonyms: 9130203F04Rik, SIP1, Zfhx1b, Zfx1b, D130016B08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 24136
Homologene: 8868
Or5aq6
Name: olfactory receptor family 5 subfamily AQ member 6
Synonyms: GA_x6K02T2Q125-48586461-48585523, MOR172-5, Olfr1109
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258762
Homologene: 86672
Vmn1r54
Name: vomeronasal 1 receptor 54
Synonyms: V1ra9, VN7
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113851
Stox1
Name: storkhead box 1
Synonyms: 4732470K04Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216021
Homologene: 17649
Sh3tc2
Name: SH3 domain and tetratricopeptide repeats 2
Synonyms: D430044G18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225608
VEGA: 18
Homologene: 11596
Gyg1
Name: glycogenin 1
Synonyms: Gyg
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 27357
HGNC: HGNC:4699
Homologene: 31219
Gm5624
Name: predicted gene 5624
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 115488302
Samd11
Name: sterile alpha motif domain containing 11
Synonyms: mr-s
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 231004
VEGA: 4
Homologene: 34983
Smok2a
Name: sperm motility kinase 2A
Synonyms: Smok2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 27263
Homologene: 128738
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 74,917,169 bp
  • T to G, chromosome 2 at 37,005,390 bp
  • T to A, chromosome 2 at 44,996,171 bp
  • T to C, chromosome 2 at 85,062,278 bp
  • T to C, chromosome 2 at 87,093,158 bp
  • T to A, chromosome 2 at 88,756,680 bp
  • A to G, chromosome 2 at 118,718,823 bp
  • T to A, chromosome 2 at 178,468,229 bp
  • C to T, chromosome 3 at 20,125,455 bp
  • A to T, chromosome 3 at 39,008,979 bp
  • T to A, chromosome 3 at 108,957,649 bp
  • T to A, chromosome 4 at 42,937,906 bp
  • T to G, chromosome 4 at 62,626,017 bp
  • A to G, chromosome 4 at 113,715,703 bp
  • C to T, chromosome 4 at 156,249,273 bp
  • C to T, chromosome 5 at 115,579,639 bp
  • A to G, chromosome 5 at 134,726,521 bp
  • A to G, chromosome 5 at 137,300,327 bp
  • T to A, chromosome 6 at 90,269,431 bp
  • A to T, chromosome 7 at 23,928,852 bp
  • A to G, chromosome 7 at 44,508,305 bp
  • T to A, chromosome 7 at 120,423,900 bp
  • T to C, chromosome 8 at 15,900,676 bp
  • T to C, chromosome 8 at 54,662,918 bp
  • A to G, chromosome 9 at 18,330,643 bp
  • T to A, chromosome 9 at 39,319,105 bp
  • A to T, chromosome 9 at 79,776,225 bp
  • C to T, chromosome 10 at 62,664,975 bp
  • T to A, chromosome 11 at 44,643,447 bp
  • A to G, chromosome 11 at 100,749,793 bp
  • A to C, chromosome 11 at 104,920,309 bp
  • T to C, chromosome 12 at 81,314,678 bp
  • T to A, chromosome 12 at 85,919,121 bp
  • C to T, chromosome 13 at 19,674,519 bp
  • A to G, chromosome 14 at 14,175,416 bp
  • T to G, chromosome 14 at 44,561,890 bp
  • C to G, chromosome 14 at 50,127,370 bp
  • T to A, chromosome 14 at 117,892,349 bp
  • T to C, chromosome 16 at 38,602,921 bp
  • A to G, chromosome 16 at 85,866,618 bp
  • T to A, chromosome 17 at 13,225,612 bp
  • C to A, chromosome 17 at 23,833,956 bp
  • T to A, chromosome 17 at 27,111,926 bp
  • T to C, chromosome 17 at 74,546,393 bp
  • T to A, chromosome 18 at 61,990,802 bp
  • G to C, chromosome 18 at 62,015,071 bp
  • A to G, chromosome 19 at 18,832,485 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8413 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
067767-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.