Strain Name:
C57BL/6J-MtgxR8429Btlr/Mmmh
Stock Number:
067774-MU
Citation ID:
RRID:MMRRC_067774-MU
Other Names:
R8429 (G1)
Major Collection:

Strain Information

Plekhj1
Name: pleckstrin homology domain containing, family J member 1
Synonyms: 9530063M10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 78670
VEGA: 10
Homologene: 11389
Epha4
Name: Eph receptor A4
Synonyms: Sek, Sek1, Tyro1, Hek8, Cek8, 2900005C20Rik, rb
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13838
HGNC: HGNC:3388
Homologene: 20933
Satb1
Name: special AT-rich sequence binding protein 1
Synonyms: 2610306G12Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20230
Homologene: 2232
Ncam2
Name: neural cell adhesion molecule 2
Synonyms: RNCAM, R4B12 antigen, Ncam-2, Ocam
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 17968
HGNC: HGNC:7657
Homologene: 3336
Pex7
Name: peroxisomal biogenesis factor 7
Synonyms: peroxisome biogenesis factor 7
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18634
HGNC: HGNC:8860
Homologene: 242
Nup155
Name: nucleoporin 155
Synonyms: D930027M19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 170762
VEGA: 15
HGNC: HGNC:8063
Homologene: 43155
Ubtd1
Name: ubiquitin domain containing 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226122
VEGA: 19
Homologene: 11799
Baz1b
Name: bromodomain adjacent to zinc finger domain, 1B
Synonyms: Wbscr9, WSTF
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22385
HGNC: HGNC:961
Homologene: 22651
Ralgapb
Name: Ral GTPase activating protein, beta subunit (non-catalytic)
Synonyms: B230339M05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228850
Homologene: 10666
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, Lek1, mitosin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Cct4
Name: chaperonin containing TCP1 subunit 4
Synonyms: A45, TCP-1 delta, T complex protein 1, delta, Cctd, 2610204B21Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12464
HGNC: HGNC:1617
Homologene: 4695
Fanci
Name: Fanconi anemia, complementation group I
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 208836
Homologene: 49530
Sh3gl1
Name: SH3-domain GRB2-like 1
Synonyms: SH3P8, EEN, endophilin II, Sh3d2b, endophilin A2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20405
VEGA: 17
Homologene: 55709
Nars1
Name: asparaginyl-tRNA synthetase 1
Synonyms: ASNRS, Nars
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70223
VEGA: 18
HGNC: HGNC:7643
Homologene: 68404
Syt17
Name: synaptotagmin XVII
Synonyms: Bk
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 110058
Homologene: 9553
C3
Name: complement component 3
Synonyms: complement factor 3, acylation stimulating protein, Plp
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12266
HGNC: HGNC:1318
Homologene: 68031
Npat
Name: nuclear protein in the AT region
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244879
HGNC: HGNC:7896
Homologene: 1888
Pcnx3
Name: pecanex homolog 3
Synonyms: Pcnxl3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 104401
Homologene: 17000
2900026A02Rik
Name: RIKEN cDNA 2900026A02 gene
Synonyms: LOC231620, Gm449
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243219
Homologene: 129566
Fnip1
Name: folliculin interacting protein 1
Synonyms: A730024A03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216742
Homologene: 28173
Btbd16
Name: BTB domain containing 16
Synonyms: E330040A16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330660
Homologene: 77327
Naxe
Name: NAD(P)HX epimerase
Synonyms: ESTM37, APOA1BP, AI-BP, Apoa1bp
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 246703
Homologene: 70948
Adgrf4
Name: adhesion G protein-coupled receptor F4
Synonyms: 4632435A09Rik, Gpr115
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78249
Homologene: 51953
Egfem1
Name: EGF-like and EMI domain containing 1
Synonyms: 6130401L20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 75740
Homologene: 135950
Man2c1
Name: mannosidase, alpha, class 2C, member 1
Synonyms: 1110025H24Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73744
HGNC: HGNC:6827
Homologene: 4887
Zfp458
Name: zinc finger protein 458
Synonyms: Rslcan-7
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238690
VEGA: 13
Homologene: 128170
Or5ac25
Name: olfactory receptor family 5 subfamily AC member 25
Synonyms: GA_x54KRFPKG5P-55590495-55589578, MOR182-6, MOR182-6, GA_x54KRFPKG5P-55580232-55579315, Olfr208, Olfr209, MOR182-9, GA_x54KRFPKG5P-55570276-55569359, Olfr207
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 404311
Homologene: 133040
Grin2b
Name: glutamate receptor, ionotropic, NMDA2B (epsilon 2)
Synonyms: NMDAR2B, NR2B, Nmdar2b, GluRepsilon2, GluN2B
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14812
HGNC: HGNC:4586
Homologene: 646
Abca6
Name: ATP-binding cassette, sub-family A member 6
Synonyms: 6330565N06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76184
HGNC: HGNC:36
Homologene: 71264
Krt13
Name: keratin 13
Synonyms: Krt-1.13, K13, Krt1-13
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16663
HGNC: HGNC:6415
Homologene: 40740
Mical2
Name: microtubule associated monooxygenase, calponin and LIM domain containing 2
Synonyms: 5330438E18Rik, Ebitein1, 4921517J23Rik, Micalcl
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 320878
Homologene: 8760
Thbd
Name: thrombomodulin
Synonyms: CD141, TM
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21824
Homologene: 308
Spata31h1
Name: SPATA31 subfamily H member 1
Synonyms: 4932415D10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 102635990
VEGA: 10
Homologene: 82476
Mfsd2b
Name: MFSD2 lysolipid transporter B, sphingolipid
Synonyms: major facilitator superfamily domain containing 2B, Gm1964
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 432628
Homologene: 47753
Nr1d2
Name: nuclear receptor subfamily 1, group D, member 2
Synonyms: Rev-erb beta, RVR
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 353187
HGNC: HGNC:7963
Homologene: 3763
Pde6a
Name: phosphodiesterase 6A, cGMP-specific, rod, alpha
Synonyms: Pdea
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225600
HGNC: HGNC:8785
Homologene: 380
Irag2
Name: inositol 1,4,5-triphosphate receptor associated 2
Synonyms: Jaw1, D6Int7, D6Int8, D6Int5, D6Int4, D6Int3, Lrmp
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16970
HGNC: HGNC:6690
Homologene: 4483
Meioc
Name: meiosis specific with coiled-coil domain
Synonyms: LOC268491, LOC380729, Gm1564
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268491
Homologene: 19559
Or10ag60
Name: olfactory receptor family 10 subfamily AG member 60
Synonyms: GA_x6K02T2Q125-49112575-49113519, MOR264-4, Olfr1130
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258835
Homologene: 133705
Foxc1
Name: forkhead box C1
Synonyms: frkhda, fkh1, fkh-1, FREAC3, Fkh1, Mf1, Mf4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17300
HGNC: HGNC:3800
Homologene: 20373
Larp1b
Name: La ribonucleoprotein 1B
Synonyms: 1700108L22Rik, 4933421B21Rik, Larp2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 214048
Homologene: 103869
Zfp78
Name: zinc finger protein 78
Synonyms: KRAB12, Zfp77
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330463
Homologene: 128524
Bin3
Name: bridging integrator 3
Synonyms: 1700015F07Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 57784
VEGA: 14
HGNC: HGNC:1054
Homologene: 5472
Nt5el
Name: 5' nucleotidase, ecto-like
Synonyms: 4933425L06Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66763
Homologene: 12028
Tmem114
Name: transmembrane protein 114
Synonyms: 4930511J11Rik, Cldn26
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74720
VEGA: 16
Homologene: 12583
Or9k2b
Name: olfactory receptor family 9 subfamily K member 2B
Synonyms: GA_x6K02T2PULF-11851623-11850682, MOR210-2, Olfr826
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258671
Homologene: 121503
Mrgprb4
Name: MAS-related GPR, member B4
Synonyms: MrgB4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233230
Homologene: 115575
Or4f4b
Name: olfactory receptor family 4 subfamily F member 4B
Synonyms: GA_x6K02T2Q125-72534883-72535821, MOR245-6, Olfr1289
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258399
Hadha
Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
Synonyms: Mtpa
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 97212
HGNC: HGNC:4801
Homologene: 152
Slc7a12
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
Synonyms: asc-type amino acid transporter 2, Asc-2, XAT1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 140918
Homologene: 76812
Hcar2
Name: hydroxycarboxylic acid receptor 2
Synonyms: PUMA-G, HM74, Pumag, Gpr109b, Gpr109a, Niacr1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 80885
Homologene: 4391
Gm45713
Name: predicted gene 45713
Type: Gene
Species: Mouse
Chromosome: 7
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 77,390,036 bp
  • C to T, chromosome 1 at 189,657,307 bp
  • G to T, chromosome 2 at 87,607,524 bp
  • G to A, chromosome 2 at 111,483,495 bp
  • G to T, chromosome 2 at 148,407,537 bp
  • C to T, chromosome 2 at 158,426,297 bp
  • A to T, chromosome 3 at 14,497,282 bp
  • G to A, chromosome 3 at 29,657,268 bp
  • A to G, chromosome 3 at 40,977,227 bp
  • C to A, chromosome 3 at 88,058,152 bp
  • T to C, chromosome 5 at 30,144,257 bp
  • T to C, chromosome 5 at 113,183,436 bp
  • C to T, chromosome 5 at 123,865,475 bp
  • A to G, chromosome 5 at 135,217,331 bp
  • T to C, chromosome 6 at 135,733,916 bp
  • C to A, chromosome 6 at 145,165,223 bp
  • T to C, chromosome 7 at 6,378,493 bp
  • T to A, chromosome 7 at 16,919,667 bp
  • T to C, chromosome 7 at 45,136,116 bp
  • A to T, chromosome 7 at 48,198,425 bp
  • T to C, chromosome 7 at 79,438,385 bp
  • T to A, chromosome 7 at 112,345,253 bp
  • T to A, chromosome 7 at 118,434,341 bp
  • G to A, chromosome 7 at 130,795,337 bp
  • C to T, chromosome 9 at 53,570,609 bp
  • T to C, chromosome 9 at 57,131,161 bp
  • T to C, chromosome 10 at 19,894,328 bp
  • C to T, chromosome 10 at 80,796,470 bp
  • G to T, chromosome 10 at 82,289,467 bp
  • A to G, chromosome 10 at 130,180,223 bp
  • T to A, chromosome 11 at 22,996,030 bp
  • A to T, chromosome 11 at 54,475,696 bp
  • A to T, chromosome 11 at 100,121,125 bp
  • A to T, chromosome 11 at 102,674,206 bp
  • A to T, chromosome 11 at 110,202,382 bp
  • G to T, chromosome 12 at 4,866,487 bp
  • A to T, chromosome 13 at 31,807,776 bp
  • A to G, chromosome 13 at 67,258,088 bp
  • A to G, chromosome 13 at 105,118,788 bp
  • G to A, chromosome 14 at 18,215,409 bp
  • A to G, chromosome 14 at 70,137,149 bp
  • C to T, chromosome 15 at 8,112,420 bp
  • A to G, chromosome 16 at 8,412,167 bp
  • A to G, chromosome 16 at 59,361,627 bp
  • A to T, chromosome 16 at 81,589,635 bp
  • G to T, chromosome 17 at 42,667,449 bp
  • A to T, chromosome 17 at 48,037,066 bp
  • A to G, chromosome 17 at 51,767,950 bp
  • T to C, chromosome 17 at 56,018,821 bp
  • A to G, chromosome 17 at 57,222,811 bp
  • T to A, chromosome 18 at 61,232,844 bp
  • A to G, chromosome 18 at 64,501,320 bp
  • C to T, chromosome 19 at 5,665,384 bp
  • G to T, chromosome 19 at 42,032,117 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8429 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
067774-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.