Strain Name:
C57BL/6J-MtgxR8900Btlr/Mmmh
Stock Number:
068757-MU
Citation ID:
RRID:MMRRC_068757-MU
Other Names:
R8900 (G1)
Major Collection:

Strain Information

Tiparp
Name: TCDD-inducible poly(ADP-ribose) polymerase
Synonyms: DDF1, PARP-7, PARP7
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99929
Homologene: 9167
Ppp1r13b
Name: protein phosphatase 1, regulatory subunit 13B
Synonyms: ASPP1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 21981
VEGA: 12
Homologene: 9090
Cwf19l2
Name: CWF19 like cell cycle control factor 2
Synonyms: 3230401L03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244672
Homologene: 12366
Dock9
Name: dedicator of cytokinesis 9
Synonyms: B230309H04Rik, D14Wsu89e, Zizimin1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105445
Homologene: 41026
Ncaph2
Name: non-SMC condensin II complex, subunit H2
Synonyms: 0610010J20Rik, 2610524G04Rik, D15Ertd785e, Kleisin beta
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 52683
Homologene: 12045
Hip1
Name: huntingtin interacting protein 1
Synonyms: 2610109B09Rik, A930014B11Rik, E130315I21Rik, HIP-1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 215114
HGNC: HGNC:4913
Homologene: 68463
Cebpa
Name: CCAAT/enhancer binding protein alpha
Synonyms: C/EBP alpha, Cebp, C/ebpalpha
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12606
HGNC: HGNC:1833
Homologene: 3211
Tcf4
Name: transcription factor 4
Synonyms: SEF-2, ITF-2, MITF-2B, MITF-2A, ME2, E2.2, TFE, E2-2, SEF2-1, ASP-I2, ITF-2b, 5730422P05Rik, bHLHb19
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 21413
Homologene: 2407
Dsp
Name: desmoplakin
Synonyms: DP, 2300002E22Rik, 5730453H04Rik, rul
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Zfp317
Name: zinc finger protein 317
Synonyms: Zfp67, KRAB9, D230022C05Rik, Zfp75
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244713
Homologene: 36389
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: VIa, sema, Sema6A-1, Semaq, A730020P05Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 20358
Homologene: 32426
Pfkl
Name: phosphofructokinase, liver, B-type
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18641
HGNC: HGNC:8876
Homologene: 55668
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, 2610100B16Rik, Odz3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23965
Homologene: 22673
Cand2
Name: cullin associated and neddylation dissociated 2 (putative)
Synonyms: Tp120b, 2210404G23Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67088
Homologene: 41657
Wdr75
Name: WD repeat domain 75
Synonyms: 1300003A18Rik, 2410118I19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 73674
Homologene: 32771
Ttf2
Name: transcription termination factor, RNA polymerase II
Synonyms: 4632434F22Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74044
Homologene: 37826
Edc4
Name: enhancer of mRNA decapping 4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234699
Homologene: 40937
Bcl2a1a
Name: B cell leukemia/lymphoma 2 related protein A1a
Synonyms: A1, Bfl-1, Bcl2a1, Hbpa1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12044
HGNC: HGNC:991
Homologene: 2988
Tbkbp1
Name: TBK1 binding protein 1
Synonyms: 3110043L15Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 73174
Homologene: 8820
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh-4, C130041O22Rik, Zfh4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80892
Homologene: 23477
Sp9
Name: trans-acting transcription factor 9
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381373
Homologene: 66935
Nxph1
Name: neurexophilin 1
Synonyms: C130005L03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18231
Homologene: 8284
Cfap74
Name: cilia and flagella associated protein 74
Synonyms: 2010015L04Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 544678
Homologene: 129584
Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Synonyms: 9430028L06Rik, 9030411M15Rik, Fam38b2, Piezo2, Fam38b
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 667742
Homologene: 49695
Itga4
Name: integrin alpha 4
Synonyms: VLA-4 receptor, alpha 4 subunit
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16401
HGNC: HGNC:6140
Homologene: 37364
Cdcp3
Name: CUB domain containing protein 3
Synonyms: 5430419D17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71395
Homologene: 138430
Or1p1
Name: olfactory receptor family 1 subfamily P member 1
Synonyms: IH3, MOR133-3P, GA_x6K02T2P1NL-4434429-4435400, Olfr59
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18359
HGNC: HGNC:8222
Homologene: 73924
Ankrd33b
Name: ankyrin repeat domain 33B
Synonyms: 0610012A05Rik, 5730557B15Rik, 3021401C12Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67434
Homologene: 12362
Daw1
Name: dynein assembly factor with WDR repeat domains 1
Synonyms: 4933429D11Rik, 4930563E19Rik, Wdr69, b2b1116Clo, b2b1584Clo
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71227
Abca9
Name: ATP-binding cassette, sub-family A member 9
Synonyms: D630040K07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217262
HGNC: HGNC:39
Homologene: 33332
Rint1
Name: RAD50 interactor 1
Synonyms: 2810450M21Rik, 1500019C06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72772
Homologene: 11070
Dnm3
Name: dynamin 3
Synonyms: B230343F03Rik, 9630020E24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 103967
Homologene: 22906
Cd101
Name: CD101 antigen
Synonyms: LOC381460, Igsf2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 630146
HGNC: HGNC:5949
Homologene: 3142
Phf19
Name: PHD finger protein 19
Synonyms: 3110009G19Rik, 3321402G02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74016
Homologene: 12524
Slc22a30
Name: solute carrier family 22, member 30
Synonyms: C730048C13Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 319800
Homologene: 77136
Vmn2r104
Name: vomeronasal 2, receptor 104
Synonyms: V2r7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22313
Homologene: 129751
Plekhn1
Name: pleckstrin homology domain containing, family N member 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 231002
VEGA: 4
Homologene: 12949
Nxpe3
Name: neurexophilin and PC-esterase domain family, member 3
Synonyms: LOC208684, LOC385658, Fam55c
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 385658
VEGA: 16
Homologene: 17030
Bst1
Name: bone marrow stromal cell antigen 1
Synonyms: 114/A10, Ly65, Bp3, Bsta1, CD157
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12182
HGNC: HGNC:1118
Homologene: 3198
Zbtb47
Name: zinc finger and BTB domain containing 47
Synonyms: 4732420M22Rik, Zfp651
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270210
VEGA: 9
Homologene: 136302
Raly
Name: hnRNP-associated with lethal yellow
Synonyms: Merc
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19383
Homologene: 7216
Vmn2r16
Name: vomeronasal 2, receptor 16
Synonyms: EG384220
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384220
Homologene: 104825
Rnf31
Name: ring finger protein 31
Synonyms: Paul, HOIP
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268749
Homologene: 33228
Cpxm1
Name: carboxypeptidase X, M14 family member 1
Synonyms: Cpx-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56264
Homologene: 10485
Arhgap22
Name: Rho GTPase activating protein 22
Synonyms: RHOGAP2, B230341L19Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239027
Homologene: 23292
Dohh
Name: deoxyhypusine hydroxylase/monooxygenase
Synonyms: 1110033C18Rik, Hlrc1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 102115
Homologene: 6290
Vmn2r17
Name: vomeronasal 2, receptor 17
Synonyms: EG384221
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384221
Homologene: 104825
Scart1
Name: scavenger receptor family member expressed on T cells 1
Synonyms: E430002D04Rik, Cd163l1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244233
Homologene: 129778
Fgf14
Name: fibroblast growth factor 14
Synonyms: Fhf4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14169
HGNC: HGNC:3671
Homologene: 3037
Tmem132b
Name: transmembrane protein 132B
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 208151
Homologene: 28135
Dus4l
Name: dihydrouridine synthase 4 like
Synonyms: 2700089B10Rik, 2310069P03Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 71916
VEGA: 12
Homologene: 6535
Adamts8
Name: ADAM metallopeptidase with thrombospondin type 1 motif 8
Synonyms: METH2, METH-2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 30806
HGNC: HGNC:224
Homologene: 5108
Clec4a4
Name: C-type lectin domain family 4, member a4
Synonyms: Dcir2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 474145
Homologene: 133910
B4galt4
Name: UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4
Synonyms: 9130402O08Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 56375
HGNC: HGNC:927
Homologene: 37848
Igfals
Name: insulin-like growth factor binding protein, acid labile subunit
Synonyms: ALS, Albs
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16005
VEGA: 17
HGNC: HGNC:5468
Homologene: 37987
Cd5l
Name: CD5 antigen-like
Synonyms: AAC-11, AIM/Spalpha, Sp-alpha, Pdp 1/6, Api6, AIM
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11801
HGNC: HGNC:1690
Homologene: 55936
Pomk
Name: protein-O-mannose kinase
Synonyms: Sgk196, 4930444A02Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74653
Homologene: 12580
Sdc1
Name: syndecan 1
Synonyms: CD138, Synd1, Synd, syn-1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20969
Homologene: 2252
Vmn2r42
Name: vomeronasal 2, receptor 42
Synonyms: V2r4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22310
Homologene: 113703
Fam220a
Name: family with sequence similarity 220, member A
Synonyms: 1500026F15Rik, 2810453I06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67238
Homologene: 57041
Vmn1r51
Name: vomeronasal 1 receptor 51
Synonyms: V1r1, VN12, V1ra1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22296
Homologene: 130651
Pcdha11
Name: protocadherin alpha 11
Synonyms: Cnr7, Crnr7, A830022B16Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12942
HGNC: HGNC:8665
Homologene: 75095
Ndufb3
Name: NADH:ubiquinone oxidoreductase subunit B3
Synonyms: 2700033I16Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66495
HGNC: HGNC:7698
Homologene: 37630
Gm45861
Name: predicted gene 45861
Type: Gene
Species: Mouse
Chromosome: 8
Or13c7e-ps1
Name: olfactory receptor family 13 subfamily C member 7E, pseudogene 1
Synonyms: MTPCR52, mOR37d, Olfr37d, Olfr29, GA_x6K02T2N78B-16154374-16155336, MOR262-11, Olfr29-ps1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 29848
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 45,799,127 bp
  • T to C, chromosome 1 at 58,595,665 bp
  • T to G, chromosome 1 at 83,198,177 bp
  • T to A, chromosome 1 at 162,307,876 bp
  • A to T, chromosome 2 at 34,905,472 bp
  • C to A, chromosome 2 at 73,273,519 bp
  • T to A, chromosome 2 at 79,314,988 bp
  • T to A, chromosome 2 at 130,393,440 bp
  • A to T, chromosome 2 at 154,863,573 bp
  • T to C, chromosome 3 at 5,398,864 bp
  • T to A, chromosome 3 at 65,553,182 bp
  • T to A, chromosome 3 at 87,367,575 bp
  • T to C, chromosome 3 at 100,952,640 bp
  • C to A, chromosome 3 at 101,018,746 bp
  • G to T, chromosome 4 at 43,781,432 bp
  • G to A, chromosome 4 at 155,436,730 bp
  • T to C, chromosome 4 at 156,225,621 bp
  • T to C, chromosome 5 at 23,811,884 bp
  • A to G, chromosome 5 at 43,820,600 bp
  • T to C, chromosome 5 at 109,363,753 bp
  • A to T, chromosome 5 at 109,427,997 bp
  • A to T, chromosome 5 at 125,778,820 bp
  • T to C, chromosome 5 at 135,430,290 bp
  • T to A, chromosome 5 at 143,563,473 bp
  • T to C, chromosome 6 at 9,247,601 bp
  • T to C, chromosome 6 at 90,129,860 bp
  • C to T, chromosome 6 at 115,780,933 bp
  • A to G, chromosome 6 at 123,023,916 bp
  • C to T, chromosome 7 at 8,194,793 bp
  • A to G, chromosome 7 at 35,120,481 bp
  • A to T, chromosome 7 at 131,302,468 bp
  • G to A, chromosome 7 at 140,228,565 bp
  • A to G, chromosome 8 at 25,983,356 bp
  • A to T, chromosome 8 at 27,529,604 bp
  • A to T, chromosome 8 at 48,236,402 bp
  • A to C, chromosome 8 at 105,891,225 bp
  • T to A, chromosome 9 at 3,447,245 bp
  • T to A, chromosome 9 at 19,647,412 bp
  • C to A, chromosome 9 at 30,954,634 bp
  • A to T, chromosome 9 at 88,957,258 bp
  • A to C, chromosome 9 at 121,767,639 bp
  • C to G, chromosome 10 at 78,000,781 bp
  • A to G, chromosome 10 at 81,387,901 bp
  • T to C, chromosome 11 at 74,289,587 bp
  • T to C, chromosome 11 at 97,149,501 bp
  • T to C, chromosome 11 at 110,154,392 bp
  • C to T, chromosome 12 at 8,790,460 bp
  • G to T, chromosome 12 at 31,640,693 bp
  • T to A, chromosome 12 at 111,872,344 bp
  • G to A, chromosome 13 at 38,181,179 bp
  • G to A, chromosome 14 at 33,271,923 bp
  • T to G, chromosome 14 at 55,596,232 bp
  • T to C, chromosome 14 at 121,580,528 bp
  • A to T, chromosome 14 at 123,983,914 bp
  • G to A, chromosome 15 at 31,297,684 bp
  • T to A, chromosome 15 at 89,369,391 bp
  • C to T, chromosome 16 at 38,752,042 bp
  • T to C, chromosome 16 at 55,844,660 bp
  • A to G, chromosome 17 at 20,041,662 bp
  • A to G, chromosome 17 at 24,880,040 bp
  • T to G, chromosome 18 at 37,012,746 bp
  • T to G, chromosome 18 at 47,291,115 bp
  • T to C, chromosome 18 at 63,115,025 bp
  • T to C, chromosome 18 at 69,564,690 bp
  • A to C, chromosome 19 at 8,337,976 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8900 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068757-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.