Strain Name:
C57BL/6J-MtgxR9020Btlr/Mmmh
Stock Number:
068850-MU
Citation ID:
RRID:MMRRC_068850-MU
Other Names:
R9020 (G1)
Major Collection:

Strain Information

Uchl3
Name: ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50933
VEGA: 14
Homologene: 4377
Gtf2i
Name: general transcription factor II I
Synonyms: BAP-135, 6030441I21Rik, TFII-I
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14886
HGNC: HGNC:4659
Homologene: 7748
Pip5k1b
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
Synonyms: Pipk5b
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18719
HGNC: HGNC:8995
Homologene: 100644
Prtg
Name: protogenin
Synonyms: A230098A12Rik, Igdcc5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235472
Homologene: 54453
Wwp1
Name: WW domain containing E3 ubiquitin protein ligase 1
Synonyms: Tiul1, SDRP1, AIP5, 8030445B08Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 107568
Homologene: 21385
Trip11
Name: thyroid hormone receptor interactor 11
Synonyms: GMAP-210, 6030460N08Rik, TRIP230, 2610511G22Rik, 3110031G15Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 109181
Homologene: 20897
Chd4
Name: chromodomain helicase DNA binding protein 4
Synonyms: D6Ertd380e, 9530019N15Rik, Mi-2beta
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 107932
HGNC: HGNC:1919
Homologene: 68175
Usp10
Name: ubiquitin specific peptidase 10
Synonyms: 2610014N07Rik, Uchrp
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 22224
Homologene: 31294
Casr
Name: calcium-sensing receptor
Synonyms: cation sensing receptor, Gprc2a, CaR
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12374
HGNC: HGNC:1514
Homologene: 332
Dmbt1
Name: deleted in malignant brain tumors 1
Synonyms: MUCLIN, CRP-[b], hensin, ebnerin, Crpd, vomeroglandin, CRP-[a], gp300
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12945
HGNC: HGNC:2926
Homologene: 68990
Plxna4
Name: plexin A4
Synonyms: Plxa4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243743
HGNC: HGNC:9102
Homologene: 77587
Apob
Name: apolipoprotein B
Synonyms: apob-48, apob-100
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Scyl2
Name: SCY1-like 2 (S. cerevisiae)
Synonyms: D10Ertd802e, CVAK104
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 213326
Homologene: 13349
Steap2
Name: six transmembrane epithelial antigen of prostate 2
Synonyms: 4921538B17Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74051
Homologene: 17682
Ifnk
Name: interferon kappa
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 387510
Homologene: 36384
Muc16
Name: mucin 16
Synonyms: 1110008I14Rik, LOC385009, Gm21044
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73732
Homologene: 141193
Btbd10
Name: BTB domain containing 10
Synonyms: Gmrp1, 1110056N09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 68815
Homologene: 13009
Lins1
Name: lines homolog 1
Synonyms: 2700083B01Rik, Wins2, Lins
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72635
Homologene: 10034
Nle1
Name: notchless homolog 1
Synonyms: Nle, l11Jus4, notchless, l11Jus1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217011
Homologene: 5494
Mavs
Name: mitochondrial antiviral signaling protein
Synonyms: D430028G21Rik, IPS-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228607
Homologene: 17004
Nphp3
Name: nephronophthisis 3 (adolescent)
Synonyms: nephrocystin 3, pcy, D330020E01Rik, 3632410F03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74025
HGNC: HGNC:7907
Homologene: 32697
Tsc2
Name: TSC complex subunit 2
Synonyms: Nafld, tuberin, tuberous sclerosis 2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22084
VEGA: 17
Homologene: 462
Tek
Name: TEK receptor tyrosine kinase
Synonyms: Tie2, tie-2, Hyk, Cd202b
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21687
Homologene: 397
Tet3
Name: tet methylcytosine dioxygenase 3
Synonyms: B430006D22Rik, D230004J03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 194388
Homologene: 35360
Iqch
Name: IQ motif containing H
Synonyms: 4921504K03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 78250
Homologene: 11258
Prdm1
Name: PR domain containing 1, with ZNF domain
Synonyms: Blimp-1, b2b1765Clo, PRDI-BF1, Blimp1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12142
HGNC: HGNC:9346
Homologene: 925
Cfap44
Name: cilia and flagella associated protein 44
Synonyms: 6330444M21Rik, Wdr52, D16Ertd642e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 212517
Homologene: 75085
Sycp1
Name: synaptonemal complex protein 1
Synonyms: SCP1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20957
Homologene: 2389
Sdr9c7
Name: 4short chain dehydrogenase/reductase family 9C, member 7
Synonyms: 1810054F20Rik, Rdhs, Sdro, Rdh20, SDR-O
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70061
Homologene: 23618
Ros1
Name: Ros1 proto-oncogene
Synonyms: Ros-1, c-ros
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19886
Homologene: 2207
Atp2a1
Name: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Synonyms: SERCA1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11937
HGNC: HGNC:811
Homologene: 7635
Cfap65
Name: cilia and flagella associated protein 65
Synonyms: B230363K08Rik, Ccdc108
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241116
Homologene: 28093
Pcdhb8
Name: protocadherin beta 8
Synonyms: PcdhbH, Pcdhb5C
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93879
HGNC: HGNC:8690
Homologene: 89038
Myo1a
Name: myosin IA
Synonyms: Myhl, BBM-I, brush border myosin 1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 432516
VEGA: 10
HGNC: HGNC:7595
Homologene: 21113
Jade2
Name: jade family PHD finger 2
Synonyms: Phf15, 1200017K05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76901
Homologene: 9082
Cyp26b1
Name: cytochrome P450, family 26, subfamily b, polypeptide 1
Synonyms: CP26, retinoic acid B1, P450RAI-2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232174
Homologene: 23179
Rsph10b
Name: radial spoke head 10 homolog B (Chlamydomonas)
Synonyms: Rsph10b2, 4930526H21Rik
Type: Gene
Species: Mouse
Chromosome: 5
Homologene: 18321
Phtf1
Name: putative homeodomain transcription factor 1
Synonyms: Phft
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18685
HGNC: HGNC:8939
Homologene: 4817
Fbxo17
Name: F-box protein 17
Synonyms: FBXO26, Fbx17, Fbg4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 50760
Homologene: 17523
Kcnt2
Name: potassium channel, subfamily T, member 2
Synonyms: E330038N15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240776
Homologene: 16121
Adora3
Name: adenosine A3 receptor
Synonyms: ARA3, A3AR, AA3R, A3R, Gpcr 2, 4930578J19Rik, 1700001D09Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11542
HGNC: HGNC:268
Homologene: 550
Serpinb9b
Name: serine (or cysteine) peptidase inhibitor, clade B, member 9b
Synonyms: Spi10, ovalbumin, SPI-CI, R86, 1600019A21Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20706
HGNC: HGNC:8955
Homologene: 137240
Acot11
Name: acyl-CoA thioesterase 11
Synonyms: BFIT1, 2010309H15Rik, 1110020M10Rik, Them1, Thea
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329910
Homologene: 11977
Slc15a5
Name: solute carrier family 15, member 5
Synonyms: 9830102E05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 277898
Homologene: 65333
Dnajc25
Name: DnaJ heat shock protein family (Hsp40) member C25
Synonyms: 2010109C08Rik, 2010203O07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72429
Homologene: 37883
Irx1
Name: Iroquois homeobox 1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16371
Homologene: 19065
Klk1b27
Name: kallikrein 1-related peptidase b27
Synonyms: Klk27, Klk21l, mGK-27
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16619
Homologene: 68141
Rasgrf2
Name: RAS protein-specific guanine nucleotide-releasing factor 2
Synonyms: Grf2, 6330417G04Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 19418
HGNC: HGNC:9876
Homologene: 2169
Mipep
Name: mitochondrial intermediate peptidase
Synonyms: 5730405E07Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 70478
VEGA: 14
HGNC: HGNC:7104
Homologene: 4337
Adrb3
Name: adrenergic receptor, beta 3
Synonyms: Adrb-3, beta 3-AR, beta3-adrenergic receptor, Beta-3 AR, Beta-3 adrenoceptor
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11556
HGNC: HGNC:288
Homologene: 37250
Kcnq5
Name: potassium voltage-gated channel, subfamily Q, member 5
Synonyms: 9230107O05Rik, D1Mgi1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226922
HGNC: HGNC:6299
Homologene: 28270
Ctdsp1
Name: CTD small phosphatase 1
Synonyms: SCP1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227292
Homologene: 100834
Filip1l
Name: filamin A interacting protein 1-like
Synonyms: 4631422O05Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78749
Homologene: 37121
Ccdc82
Name: coiled-coil domain containing 82
Synonyms: 2310043N13Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66396
VEGA: 9
Homologene: 11678
Kcne4
Name: potassium voltage-gated channel, Isk-related subfamily, gene 4
Synonyms: MiRP3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 57814
HGNC: HGNC:6244
Homologene: 10959
Gm9758
Name: predicted gene 9758
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381714
Homologene: 69402
Ttc6
Name: tetratricopeptide repeat domain 6
Synonyms: Gm9813, LOC217602, EG639426, AU024163, 4921506M07Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 70846
Homologene: 78002
Scgb1b3
Name: secretoglobin, family 1B, member 3
Synonyms: Abpa3, Gm5325
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 384585
Homologene: 114479
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 21,469,239 bp
  • T to C, chromosome 1 at 74,395,517 bp
  • T to C, chromosome 1 at 74,920,393 bp
  • T to A, chromosome 1 at 78,817,708 bp
  • T to A, chromosome 1 at 140,584,311 bp
  • A to G, chromosome 2 at 131,246,674 bp
  • T to C, chromosome 3 at 102,876,337 bp
  • C to G, chromosome 3 at 103,991,378 bp
  • T to A, chromosome 3 at 105,907,825 bp
  • T to C, chromosome 4 at 19,650,282 bp
  • T to C, chromosome 4 at 35,152,573 bp
  • C to A, chromosome 4 at 59,003,470 bp
  • C to G, chromosome 4 at 94,820,102 bp
  • A to G, chromosome 4 at 106,748,418 bp
  • T to C, chromosome 5 at 5,673,480 bp
  • A to C, chromosome 5 at 14,914,725 bp
  • T to C, chromosome 5 at 134,246,561 bp
  • G to A, chromosome 5 at 143,985,465 bp
  • T to A, chromosome 6 at 32,234,562 bp
  • T to C, chromosome 6 at 83,404,436 bp
  • C to T, chromosome 6 at 84,575,074 bp
  • T to A, chromosome 6 at 125,107,506 bp
  • T to A, chromosome 6 at 138,055,706 bp
  • A to T, chromosome 7 at 28,737,357 bp
  • A to G, chromosome 7 at 31,375,851 bp
  • T to A, chromosome 7 at 44,055,694 bp
  • A to G, chromosome 7 at 66,708,213 bp
  • T to C, chromosome 7 at 113,351,850 bp
  • T to C, chromosome 7 at 126,446,963 bp
  • T to A, chromosome 7 at 131,111,058 bp
  • A to T, chromosome 8 at 27,227,919 bp
  • T to G, chromosome 8 at 119,941,165 bp
  • C to T, chromosome 9 at 13,281,425 bp
  • G to GAATGGCTTTCTT, chromosome 9 at 18,638,719 bp
  • T to C, chromosome 9 at 63,525,244 bp
  • C to T, chromosome 9 at 72,891,995 bp
  • T to C, chromosome 9 at 104,031,951 bp
  • A to G, chromosome 10 at 44,440,040 bp
  • T to A, chromosome 10 at 52,154,927 bp
  • A to G, chromosome 10 at 74,645,611 bp
  • T to C, chromosome 10 at 89,652,996 bp
  • C to A, chromosome 10 at 127,714,123 bp
  • T to A, chromosome 10 at 127,909,790 bp
  • T to A, chromosome 11 at 51,817,627 bp
  • C to G, chromosome 11 at 82,906,449 bp
  • A to G, chromosome 12 at 8,013,999 bp
  • A to G, chromosome 12 at 57,705,580 bp
  • A to G, chromosome 12 at 101,884,511 bp
  • A to T, chromosome 13 at 33,039,904 bp
  • A to T, chromosome 13 at 71,963,429 bp
  • A to G, chromosome 13 at 92,028,638 bp
  • T to A, chromosome 14 at 60,831,228 bp
  • A to T, chromosome 14 at 101,666,550 bp
  • A to G, chromosome 16 at 36,495,249 bp
  • T to A, chromosome 16 at 44,437,159 bp
  • A to G, chromosome 16 at 57,570,695 bp
  • G to T, chromosome 17 at 24,626,717 bp
  • T to G, chromosome 18 at 37,356,784 bp
  • T to A, chromosome 19 at 24,350,221 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9020 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068850-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.