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Strain Name:
C57BL/6J-MtgxR9029Btlr/Mmmh
Stock Number:
068858-MU
Citation ID:
RRID:MMRRC_068858-MU
Other Names:
R9029 (G1)
Major Collection:

Strain Information

Slc12a1
Name: solute carrier family 12, member 1
Synonyms: Nkcc2, mBSC1, D630042G03Rik, urehr3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20495
Homologene: 286
Vps41
Name: VPS41 HOPS complex subunit
Synonyms: Vam2, mVam2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218035
VEGA: 13
Homologene: 69165
Tnrc6b
Name: trinucleotide repeat containing 6b
Synonyms: A730065C02Rik, D230019K20Rik, 2700090M07Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 213988
VEGA: 15
Homologene: 66194
Dhrs3
Name: dehydrogenase/reductase 3
Synonyms: retSDR1, Rsdr1, dehydrogenase/reductase (SDR family) member 3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20148
Homologene: 20994
Epb41l4a
Name: erythrocyte membrane protein band 4.1 like 4a
Synonyms: NBL4, Epb4.1l4a
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13824
VEGA: 18
Homologene: 8398
Luc7l3
Name: LUC7-like 3 (S. cerevisiae)
Synonyms: 3300001P08Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67684
Homologene: 75056
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 130,159,689 bp
  • G to A, chromosome 1 at 156,313,022 bp
  • A to G, chromosome 2 at 86,676,487 bp
  • C to G, chromosome 2 at 125,154,084 bp
  • C to A, chromosome 2 at 130,029,760 bp
  • G to T, chromosome 3 at 41,082,670 bp
  • A to T, chromosome 3 at 96,684,144 bp
  • A to G, chromosome 4 at 19,535,292 bp
  • A to G, chromosome 4 at 40,738,361 bp
  • T to C, chromosome 4 at 62,085,303 bp
  • A to G, chromosome 4 at 63,169,467 bp
  • T to C, chromosome 4 at 94,618,034 bp
  • A to G, chromosome 4 at 112,253,954 bp
  • A to G, chromosome 4 at 144,927,185 bp
  • C to T, chromosome 5 at 30,370,075 bp
  • G to A, chromosome 5 at 32,281,735 bp
  • G to A, chromosome 5 at 96,098,277 bp
  • G to A, chromosome 5 at 123,175,910 bp
  • G to A, chromosome 5 at 138,298,034 bp
  • A to T, chromosome 6 at 84,577,053 bp
  • T to A, chromosome 6 at 122,084,369 bp
  • A to C, chromosome 6 at 133,055,218 bp
  • A to T, chromosome 7 at 4,927,920 bp
  • C to T, chromosome 7 at 43,938,366 bp
  • A to G, chromosome 7 at 105,753,712 bp
  • T to C, chromosome 8 at 13,953,840 bp
  • A to C, chromosome 8 at 90,270,236 bp
  • G to A, chromosome 8 at 90,956,570 bp
  • T to A, chromosome 9 at 67,948,147 bp
  • A to T, chromosome 9 at 77,027,014 bp
  • C to T, chromosome 10 at 109,863,752 bp
  • G to T, chromosome 10 at 129,802,057 bp
  • T to C, chromosome 11 at 3,224,716 bp
  • T to C, chromosome 11 at 74,195,737 bp
  • T to C, chromosome 11 at 77,437,628 bp
  • A to G, chromosome 11 at 94,297,850 bp
  • T to C, chromosome 11 at 94,664,636 bp
  • T to C, chromosome 11 at 121,512,323 bp
  • T to A, chromosome 13 at 18,810,553 bp
  • T to G, chromosome 13 at 55,806,334 bp
  • C to A, chromosome 13 at 67,320,925 bp
  • T to A, chromosome 13 at 76,688,622 bp
  • T to A, chromosome 14 at 34,017,369 bp
  • T to A, chromosome 14 at 57,918,906 bp
  • T to C, chromosome 15 at 79,084,212 bp
  • T to C, chromosome 15 at 80,878,978 bp
  • T to A, chromosome 17 at 21,745,340 bp
  • C to T, chromosome 17 at 24,891,532 bp
  • C to G, chromosome 17 at 25,013,910 bp
  • T to C, chromosome 17 at 25,864,015 bp
  • C to T, chromosome 17 at 46,687,980 bp
  • T to A, chromosome 18 at 5,056,239 bp
  • A to C, chromosome 18 at 33,878,989 bp
  • A to T, chromosome 18 at 84,013,514 bp
  • G to A, chromosome 19 at 40,912,781 bp
  • C to A, chromosome 19 at 41,871,279 bp
  • A to T, chromosome 19 at 47,864,398 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9029 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068858-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.