Strain Name:
C57BL/6J-MtgxR9064Btlr/Mmmh
Stock Number:
068889-MU
Citation ID:
RRID:MMRRC_068889-MU
Other Names:
R9064 (G1)
Major Collection:

Strain Information

Jarid2
Name: jumonji and AT-rich interaction domain containing 2
Synonyms: Jmj, jumonji
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16468
HGNC: HGNC:6196
Homologene: 31279
Proser1
Name: proline and serine rich 1
Synonyms: 2810046L04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 212127
Homologene: 13463
Kdm5a
Name: lysine demethylase 5A
Synonyms: Jarid1a, RBP2, Rbbp2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 214899
HGNC: HGNC:9886
Homologene: 3419
Mdm2
Name: transformed mouse 3T3 cell double minute 2
Synonyms: 1700007J15Rik, Mdm-2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17246
HGNC: HGNC:6973
Homologene: 1793
Phip
Name: pleckstrin homology domain interacting protein
Synonyms: Wdr11, 2810004D21Rik, 4632404O06Rik, Ndrp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 83946
Homologene: 41209
Ank3
Name: ankyrin 3, epithelial
Synonyms: 2900054D09Rik, Ank-3, Ankyrin-G, AnkG, Ankyrin-3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Sucla2
Name: succinate-Coenzyme A ligase, ADP-forming, beta subunit
Synonyms: 4930547K18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 20916
Homologene: 2856
Fntb
Name: farnesyltransferase, CAAX box, beta
Synonyms: 2010013E13Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 110606
Homologene: 1535
Ankrd28
Name: ankyrin repeat domain 28
Synonyms: E430019N21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105522
VEGA: 14
Homologene: 35374
C2cd3
Name: C2 calcium-dependent domain containing 3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 277939
Homologene: 19524
Vps8
Name: VPS8 CORVET complex subunit
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 209018
Homologene: 44592
Frzb
Name: frizzled-related protein
Synonyms: frzb-1, Frp, fritz, Sfrp3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20378
HGNC: HGNC:3959
Homologene: 1126
Kcnh5
Name: potassium voltage-gated channel, subfamily H (eag-related), member 5
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238271
VEGA: 12
HGNC: HGNC:6254
Homologene: 15858
Chd2
Name: chromodomain helicase DNA binding protein 2
Synonyms: 2810040A01Rik, 5630401D06Rik, 2810013C04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244059
HGNC: HGNC:1917
Homologene: 37462
Rreb1
Name: ras responsive element binding protein 1
Synonyms: 1110037N09Rik, B930013M22Rik, sao
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 68750
Homologene: 2218
Psmd11
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Synonyms: 2610024G20Rik, 1700089D09Rik, 2810055C24Rik, C78232, 1810019E17Rik, S9, P44.5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69077
HGNC: HGNC:9556
Homologene: 2108
Prdm4
Name: PR domain containing 4
Synonyms: 2810470D21Rik, 1700031E19Rik, SC1, SC-1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 72843
VEGA: 10
HGNC: HGNC:9348
Homologene: 8235
Supt3
Name: SPT3, SAGA and STAGA complex component
Synonyms: Supt3h, SPT3, 2310066G22Rik, SPT3L
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 109115
Homologene: 121570
Rbm45
Name: RNA binding motif protein 45
Synonyms: Drbp1, G430095G15Rik, Drb1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241490
Homologene: 15560
Atp8b1
Name: ATPase, class I, type 8B, member 1
Synonyms: Ic, FIC1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 54670
VEGA: 18
HGNC: HGNC:3706
Homologene: 21151
Spink5
Name: serine peptidase inhibitor, Kazal type 5
Synonyms: 2310065D10Rik, LEKT1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 72432
Homologene: 4987
Sirpa
Name: signal-regulatory protein alpha
Synonyms: Idd13.2, Bit, Ptpns1, SHPS-1, SIRP, CD172a, P84
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19261
HGNC: HGNC:9662
Homologene: 7246
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: Dnahc6, A730004I20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Mylk3
Name: myosin light chain kinase 3
Synonyms: D830007F02Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 213435
Homologene: 35278
Adgrb3
Name: adhesion G protein-coupled receptor B3
Synonyms: A830096D10Rik, Bai3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210933
HGNC: HGNC:945
Homologene: 1289
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: OTTMUSG00000005786, LOC380698
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Kremen2
Name: kringle containing transmembrane protein 2
Synonyms: Krm2, 2900054E04Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 73016
VEGA: 17
Homologene: 65132
Acss1
Name: acyl-CoA synthetase short-chain family member 1
Synonyms: Acas2, 1110032O15Rik, AceCS2, Acas2l
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68738
Homologene: 56037
Stil
Name: Scl/Tal1 interrupting locus
Synonyms: Sil
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20460
Homologene: 2283
Cep126
Name: centrosomal protein 126
Synonyms: AK129341
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 234915
VEGA: 9
Homologene: 28313
Tmc5
Name: transmembrane channel-like gene family 5
Synonyms: 4932443L08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74424
Homologene: 11713
Hecw2
Name: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Synonyms: A730039N16Rik, D030049F17Rik, Nedl2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329152
Homologene: 66192
Or10w1
Name: olfactory receptor family 10 subfamily W member 1
Synonyms: Olfr1490, GA_x6K02T2RE5P-3987000-3987950, MOR266-6P
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258098
Homologene: 79418
Nol4
Name: nucleolar protein 4
Synonyms: 4930568N03Rik, LOC383304, 1700013J13Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 319211
HGNC: HGNC:7870
Homologene: 36142
Calr3
Name: calreticulin 3
Synonyms: 1700031L01Rik, 6330586I20Rik, Crt2, calsperin
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 73316
Homologene: 57091
Fam118a
Name: family with sequence similarity 118, member A
Synonyms: C230014M12Rik, 3110048E14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 73225
VEGA: 15
HGNC: HGNC:1313
Homologene: 9911
Or10j3b
Name: olfactory receptor family 10 subfamily J member 3B
Synonyms: MOR267-2, GA_x6K02T2R7CC-630397-629456, Olfr1404
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258881
Homologene: 133587
Cenpq
Name: centromere protein Q
Synonyms: 2610528M18Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 83815
Homologene: 49525
Gm4841
Name: predicted gene 4841
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225594
VEGA: 18
Cyp3a41b
Name: cytochrome P450, family 3, subfamily a, polypeptide 41B
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100041375
HGNC: HGNC:2638
Homologene: 133568
Exd2
Name: exonuclease 3'-5' domain containing 2
Synonyms: 4930539P14Rik, Exdl2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 97827
VEGA: 12
Homologene: 10066
Armh1
Name: armadillo-like helical domain containing 1
Synonyms: LOC381544, Gm1661, Ncrna00082, LOC381543
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381544
Homologene: 28727
Fbxo40
Name: F-box protein 40
Synonyms: 9830003A13Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 207215
Homologene: 9459
Mcat
Name: malonyl CoA:ACP acyltransferase (mitochondrial)
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223722
VEGA: 15
Homologene: 15511
Slc26a9
Name: solute carrier family 26, member 9
Synonyms: anion transporter/exchanger-9, E030002L01Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 320718
Homologene: 14179
Nxpe4
Name: neurexophilin and PC-esterase domain family, member 4
Synonyms: D930028F11Rik, Fam55d
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244853
VEGA: 9
Homologene: 83471
Rassf10
Name: Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
Synonyms: 4632411J06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 78748
Homologene: 121963
Rpp25
Name: ribonuclease P/MRP 25 subunit
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102614
VEGA: 9
Homologene: 23048
Or14c42-ps1
Name: olfactory receptor family 14 subfamily C member 42, pseudogene 1
Synonyms: GA_x6K02T2NHDJ-9553029-9552092, Olfr296-ps1, MOR220-5_p
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404375
Nxt2
Name: nuclear transport factor 2-like export factor 2
Synonyms: P15-2, 6330587F24Rik
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 237082
Homologene: 10273
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 25,531,884 bp
  • C to A, chromosome 1 at 53,826,886 bp
  • T to A, chromosome 1 at 131,752,965 bp
  • C to T, chromosome 1 at 173,216,493 bp
  • T to C, chromosome 2 at 76,372,102 bp
  • A to G, chromosome 2 at 80,446,708 bp
  • A to T, chromosome 2 at 129,616,540 bp
  • T to C, chromosome 2 at 150,621,590 bp
  • C to T, chromosome 3 at 53,477,506 bp
  • T to G, chromosome 4 at 115,041,735 bp
  • C to A, chromosome 4 at 117,237,658 bp
  • C to T, chromosome 5 at 145,578,100 bp
  • C to A, chromosome 6 at 73,149,173 bp
  • TAGAAGAAG to TAGAAG, chromosome 6 at 120,426,908 bp
  • A to T, chromosome 7 at 73,493,531 bp
  • A to G, chromosome 7 at 86,562,163 bp
  • A to G, chromosome 7 at 100,410,401 bp
  • A to T, chromosome 7 at 112,955,108 bp
  • G to T, chromosome 7 at 118,634,047 bp
  • T to C, chromosome 8 at 72,434,830 bp
  • T to C, chromosome 8 at 85,355,311 bp
  • T to C, chromosome 9 at 8,103,340 bp
  • T to C, chromosome 9 at 48,398,664 bp
  • G to T, chromosome 9 at 57,504,352 bp
  • C to T, chromosome 9 at 82,871,487 bp
  • T to C, chromosome 10 at 69,986,355 bp
  • T to C, chromosome 10 at 85,901,814 bp
  • T to C, chromosome 10 at 117,702,330 bp
  • G to T, chromosome 11 at 59,009,109 bp
  • T to C, chromosome 11 at 80,445,243 bp
  • A to T, chromosome 12 at 75,130,953 bp
  • A to G, chromosome 12 at 76,887,866 bp
  • T to C, chromosome 12 at 80,484,374 bp
  • A to G, chromosome 13 at 37,931,350 bp
  • G to T, chromosome 13 at 44,840,850 bp
  • G to A, chromosome 14 at 31,732,048 bp
  • A to T, chromosome 14 at 73,590,863 bp
  • A to T, chromosome 15 at 44,562,642 bp
  • A to C, chromosome 15 at 83,547,933 bp
  • T to C, chromosome 15 at 85,045,838 bp
  • T to C, chromosome 16 at 21,470,229 bp
  • A to G, chromosome 16 at 32,754,397 bp
  • A to T, chromosome 16 at 36,970,640 bp
  • A to G, chromosome 17 at 23,742,762 bp
  • G to A, chromosome 17 at 40,932,840 bp
  • G to A, chromosome 17 at 44,994,408 bp
  • T to A, chromosome 18 at 22,770,793 bp
  • T to G, chromosome 18 at 43,967,126 bp
  • T to C, chromosome 18 at 60,270,889 bp
  • A to G, chromosome 18 at 64,564,420 bp
  • G to A, chromosome 19 at 13,655,355 bp
  • C to T, chromosome X at 142,237,751 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9064 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068889-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.