Strain Name:
C57BL/6J-MtgxR9089Btlr/Mmmh
Stock Number:
068907-MU
Citation ID:
RRID:MMRRC_068907-MU
Other Names:
R9089 (G1)
Major Collection:

Strain Information

Notch3
Name: notch 3
Synonyms: hpbk, N3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18131
HGNC: HGNC:7883
Homologene: 376
Lgi1
Name: leucine-rich repeat LGI family, member 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56839
HGNC: HGNC:6572
Homologene: 3737
Blm
Name: Bloom syndrome, RecQ like helicase
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12144
HGNC: HGNC:1058
Homologene: 47902
Kdm5b
Name: lysine demethylase 5B
Synonyms: Plu1, 2010009J12Rik, D1Ertd202e, Rb-Bp2, Jarid1b, 2210016I17Rik, PLU-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75605
Homologene: 48448
Adgrl3
Name: adhesion G protein-coupled receptor L3
Synonyms: 5430402I23Rik, LEC3, Lphn3, D130075K09Rik, lectomedin 3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 319387
Homologene: 22878
Cdk13
Name: cyclin dependent kinase 13
Synonyms: Cdc2l5, 2310015O17Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 69562
VEGA: 13
HGNC: HGNC:1733
Homologene: 135707
Dido1
Name: death inducer-obliterator 1
Synonyms: C130092D22Rik, D130048F08Rik, dido, Datf1, DIO-1, 6720461J16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 23856
HGNC: HGNC:2680
Homologene: 34139
Klhdc4
Name: kelch domain containing 4
Synonyms: G430025P05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234825
Homologene: 69234
Sec62
Name: SEC62 homolog, preprotein translocation
Synonyms: Dtrp1, Tloc1, 3100002M17Rik, SEC62, HTP1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69276
Homologene: 2449
Sart3
Name: squamous cell carcinoma antigen recognized by T cells 3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 53890
Homologene: 40977
Med15
Name: mediator complex subunit 15
Synonyms: Pcqap, A230074L19Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 94112
VEGA: 16
Cstf1
Name: cleavage stimulation factor, 3' pre-RNA, subunit 1
Synonyms: 1700057K18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67337
HGNC: HGNC:2483
Homologene: 1012
Eftud2
Name: elongation factor Tu GTP binding domain containing 2
Synonyms: Snrp116, U5-116kD, 116kDa
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20624
Homologene: 3133
Ipo7
Name: importin 7
Synonyms: A330055O14Rik, Imp7, RanBP7
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233726
HGNC: HGNC:9852
Homologene: 4659
Slc45a4
Name: solute carrier family 45, member 4
Synonyms: 9330175B01Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 106068
Homologene: 69908
Lrp6
Name: low density lipoprotein receptor-related protein 6
Synonyms: skam26Jus, skax26, Cd, ska26
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16974
HGNC: HGNC:6698
Homologene: 1747
Nemf
Name: nuclear export mediator factor
Synonyms: 4933405E14Rik, Sdccag1, 1500011I12Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 66244
VEGA: 12
Homologene: 3458
Gga1
Name: golgi associated, gamma adaptin ear containing, ARF binding protein 1
Synonyms: 4930406E12Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 106039
VEGA: 15
Homologene: 39250
Ralgapa1
Name: Ral GTPase activating protein, alpha subunit 1
Synonyms: Tulip1, Garnl1, 2310003F20Rik, 4930400K19Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56784
VEGA: 12
Homologene: 84805
Lhx2
Name: LIM homeobox protein 2
Synonyms: ap, Lh-2, apterous, LH2A
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16870
HGNC: HGNC:6594
Homologene: 55848
Vps50
Name: VPS50 EARP/GARPII complex subunit
Synonyms: 1700034M03Rik, 8430415E05Rik, Ccdc132
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 73288
Homologene: 11498
Muc16
Name: mucin 16
Synonyms: 1110008I14Rik, Gm21044, LOC385009
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73732
Homologene: 141193
Itpa
Name: inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
Synonyms: Itp, 2010016I08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16434
HGNC: HGNC:6176
Homologene: 6289
Map2
Name: microtubule-associated protein 2
Synonyms: G1-397-34, Mtap2, repro4, MAP-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Deaf1
Name: DEAF1, transcription factor
Synonyms: suppressin, NUDR, C230009B13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 54006
Homologene: 9647
Ddx41
Name: DEAD box helicase 41
Synonyms: 2900024F02Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72935
VEGA: 13
Homologene: 9431
Tmtc1
Name: transmembrane and tetratricopeptide repeat containing 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387314
Homologene: 65299
Tnfrsf25
Name: tumor necrosis factor receptor superfamily, member 25
Synonyms: Tnfrsf12, APO-3, DR3, DDR3, TRAMP, LARD, Wsl, WSL-1, WSL-LR, TR3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 85030
Homologene: 13202
Itpr3
Name: inositol 1,4,5-triphosphate receptor 3
Synonyms: Ip3r3, Itpr-3, tf
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16440
HGNC: HGNC:6182
Homologene: 1675
Barx2
Name: BarH-like homeobox 2
Synonyms: Barx2b, 2310006E12Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12023
HGNC: HGNC:956
Homologene: 2715
Itga11
Name: integrin alpha 11
Synonyms: 4732459H24Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 319480
HGNC: HGNC:6136
Homologene: 8151
Reln
Name: reelin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19699
HGNC: HGNC:9957
Homologene: 3699
Scin
Name: scinderin
Synonyms: adseverin
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20259
Homologene: 36296
Unc13b
Name: unc-13 homolog B
Synonyms: Munc13-2, Unc13h2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22249
Homologene: 31376
Ush2a
Name: usherin
Synonyms: Ushrn, A930037M10Rik, MUSH2A, LOC269160, A930011D15Rik, LOC381317, Ush2a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Sh3rf1
Name: SH3 domain containing ring finger 1
Synonyms: Posh, 2200003J05Rik, Sh3md2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 59009
Homologene: 10988
Helz2
Name: helicase with zinc finger 2, transcriptional coactivator
Synonyms: BC006779
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 229003
Homologene: 14118
Got1l1
Name: glutamic-oxaloacetic transaminase 1-like 1
Synonyms: 1700083M11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76615
Homologene: 65045
Synm
Name: synemin, intermediate filament protein
Synonyms: Synemin, Dmn, 4930412K21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233335
Homologene: 9081
Bckdha
Name: branched chain ketoacid dehydrogenase E1, alpha polypeptide
Synonyms: BCKAD E1[a]
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12039
HGNC: HGNC:986
Homologene: 569
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Gm7455, Col6a5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 665033
Homologene: 122792
Adgb
Name: androglobin
Synonyms: 9130014G24Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215772
Homologene: 100289
Kynu
Name: kynureninase
Synonyms: L-kynurenine hydrolase, 4432411A05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70789
HGNC: HGNC:6469
Homologene: 2925
Parp2
Name: poly (ADP-ribose) polymerase family, member 2
Synonyms: Adprt2, Aspartl2, Adprtl2, C78626, PARP-2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 11546
VEGA: 14
HGNC: HGNC:272
Homologene: 4004
Vwa5b1
Name: von Willebrand factor A domain containing 5B1
Synonyms: 4931403E03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 75718
Homologene: 19431
Cd96
Name: CD96 antigen
Synonyms: 1700109I12Rik, Tactile
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 84544
Homologene: 68489
Dmwd
Name: dystrophia myotonica-containing WD repeat motif
Synonyms: Dm9, DMR-N9, 59
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13401
HGNC: HGNC:2936
Homologene: 22559
Zfp422
Name: zinc finger protein 422
Synonyms: KOX15, Krox-26, Krox26, Krox-25-2, 2900028O21Rik, Krox25
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67255
Homologene: 5067
Csgalnact2
Name: chondroitin sulfate N-acetylgalactosaminyltransferase 2
Synonyms: 4632415D10Rik, Galnact2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78752
Homologene: 23109
Or6c70
Name: olfactory receptor family 6 subfamily C member 70
Synonyms: GA_x6K02T2PULF-11553313-11552381, MOR113-5, Olfr814, MOR113-8
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 259165
Homologene: 133585
Nphp4
Name: nephronophthisis 4 (juvenile) homolog (human)
Synonyms: nmf192, 4930564O18Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 260305
Homologene: 9024
Klk1b1
Name: kallikrein 1-related peptidase b1
Synonyms: tissue kallikrein, Klk1, mGK-1, mK1, TK
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16623
Homologene: 68141
Acadsb
Name: acyl-Coenzyme A dehydrogenase, short/branched chain
Synonyms: 1300003O09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66885
HGNC: HGNC:91
Homologene: 1216
Kbtbd4
Name: kelch repeat and BTB (POZ) domain containing 4
Synonyms: 2510026C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67136
Homologene: 32320
Vmn1r75
Name: vomeronasal 1 receptor 75
Synonyms: V1rg6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 171241
Homologene: 44234
Or2a52
Name: olfactory receptor family 2 subfamily A member 52
Synonyms: MOR261-11, Olfr437, GA_x6K02T2P3E9-4391088-4390156
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258293
HGNC: HGNC:8230
Homologene: 122778
Plk5
Name: polo like kinase 5
Synonyms: 6330514A18Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216166
Homologene: 28072
Ccdc121rt2
Name: coiled-coil domain containing 121, retrogene 2
Synonyms: Gm6588
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 625464
Homologene: 116059
Serpina3a
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3A
Synonyms: 4933406L18Rik, antitrypsin, alpha-1 antiproteinase,
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74069
HGNC: HGNC:16
Semg1
Name: semenogelin 1
Synonyms: Svs2, SVS II, semenoclotin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 53878
Homologene: 49325
Ager
Name: advanced glycosylation end product-specific receptor
Synonyms: RAGE
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 11596
HGNC: HGNC:320
Homologene: 883
Or1e31
Name: olfactory receptor family 1 subfamily E member 31
Synonyms: Olfr391-ps1, GA_x6K02T2P1NL-3951666-3950698, MOR135-24, Olfr391-ps, Olfr391, MOR135-30_i
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258236
Zdhhc21
Name: zinc finger, DHHC domain containing 21
Synonyms: 9130404H11Rik, dep, D130004H04Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68268
Homologene: 32668
Pcdhgc3
Name: protocadherin gamma subfamily C, 3
Synonyms: Pcdh2, PC43
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93706
HGNC: HGNC:8716
Homologene: 31099
1700122O11Rik
Name: RIKEN cDNA 1700122O11 gene
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 76651
Gm43518
Name: predicted gene 43518
Type: Gene
Species: Mouse
Chromosome: 5
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 66,412,939 bp
  • T to A, chromosome 1 at 134,607,768 bp
  • T to A, chromosome 1 at 188,755,177 bp
  • A to G, chromosome 2 at 38,360,033 bp
  • T to A, chromosome 2 at 43,599,608 bp
  • A to T, chromosome 2 at 90,907,565 bp
  • T to A, chromosome 2 at 130,667,937 bp
  • A to G, chromosome 2 at 164,237,421 bp
  • T to A, chromosome 2 at 172,375,887 bp
  • C to T, chromosome 2 at 180,661,500 bp
  • A to T, chromosome 2 at 181,239,640 bp
  • T to A, chromosome 3 at 30,814,234 bp
  • T to G, chromosome 4 at 43,095,847 bp
  • T to A, chromosome 4 at 82,807,055 bp
  • T to A, chromosome 4 at 138,569,431 bp
  • T to A, chromosome 4 at 152,117,472 bp
  • T to C, chromosome 4 at 152,561,216 bp
  • G to T, chromosome 5 at 21,925,200 bp
  • C to A, chromosome 5 at 81,660,444 bp
  • A to T, chromosome 5 at 112,450,891 bp
  • C to A, chromosome 5 at 113,753,695 bp
  • T to C, chromosome 5 at 123,934,266 bp
  • T to C, chromosome 6 at 3,536,884 bp
  • A to T, chromosome 6 at 43,167,983 bp
  • A to C, chromosome 6 at 116,627,125 bp
  • A to T, chromosome 6 at 118,121,022 bp
  • G to C, chromosome 6 at 134,511,206 bp
  • A to T, chromosome 6 at 148,245,717 bp
  • T to C, chromosome 7 at 11,880,526 bp
  • T to C, chromosome 7 at 19,078,055 bp
  • A to C, chromosome 7 at 25,641,719 bp
  • A to G, chromosome 7 at 43,971,244 bp
  • T to C, chromosome 7 at 67,759,018 bp
  • A to T, chromosome 7 at 80,513,119 bp
  • T to A, chromosome 7 at 110,044,459 bp
  • T to C, chromosome 7 at 131,425,775 bp
  • A to T, chromosome 7 at 141,297,552 bp
  • A to T, chromosome 8 at 27,200,861 bp
  • T to C, chromosome 8 at 61,372,579 bp
  • C to T, chromosome 8 at 121,797,945 bp
  • A to T, chromosome 9 at 18,644,550 bp
  • C to A, chromosome 9 at 31,854,147 bp
  • A to G, chromosome 9 at 62,771,380 bp
  • A to C, chromosome 9 at 105,888,943 bp
  • T to C, chromosome 10 at 10,442,688 bp
  • C to G, chromosome 10 at 80,357,996 bp
  • A to G, chromosome 10 at 129,874,619 bp
  • A to G, chromosome 11 at 73,799,226 bp
  • A to G, chromosome 11 at 102,869,145 bp
  • A to T, chromosome 12 at 40,081,704 bp
  • A to C, chromosome 12 at 55,676,566 bp
  • A to C, chromosome 12 at 69,353,854 bp
  • T to C, chromosome 12 at 104,119,697 bp
  • A to T, chromosome 13 at 17,803,859 bp
  • A to T, chromosome 13 at 55,535,611 bp
  • A to G, chromosome 14 at 50,814,870 bp
  • T to C, chromosome 15 at 73,586,104 bp
  • A to G, chromosome 15 at 78,889,752 bp
  • G to A, chromosome 16 at 17,655,557 bp
  • G to T, chromosome 16 at 46,049,705 bp
  • G to A, chromosome 17 at 27,118,677 bp
  • T to C, chromosome 17 at 32,151,547 bp
  • C to A, chromosome 17 at 34,600,605 bp
  • T to A, chromosome 17 at 48,037,142 bp
  • T to C, chromosome 18 at 37,808,211 bp
  • T to C, chromosome 19 at 38,305,647 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9089 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068907-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.