Strain Name:
C57BL/6J-MtgxR9097Btlr/Mmmh
Stock Number:
068912-MU
Citation ID:
RRID:MMRRC_068912-MU
Other Names:
R9097 (G1)
Major Collection:

Strain Information

Mtrr
Name: 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 210009
VEGA: 13
HGNC: HGNC:7473
Homologene: 11419
Sez6
Name: seizure related gene 6
Synonyms: sez-6, D11Bhm177e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20370
Homologene: 10948
Dlc1
Name: deleted in liver cancer 1
Synonyms: p122-RhoGAP, Arhgap7, A730069N07Rik, STARD12
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 50768
HGNC: HGNC:2897
Homologene: 4442
Ppp1r9a
Name: protein phosphatase 1, regulatory subunit 9A
Synonyms: 2810430P21Rik, A230094E16Rik, Neurabin I, 4930518N04Rik, neurabin-I, NRB
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243725
Homologene: 14247
Prkca
Name: protein kinase C, alpha
Synonyms: Pkca
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18750
HGNC: HGNC:9393
Homologene: 55679
Uhmk1
Name: U2AF homology motif (UHM) kinase 1
Synonyms: Kist, OTTMUSG00000021542, C820018A03Rik, KIS
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16589
Homologene: 7801
Rrp12
Name: ribosomal RNA processing 12 homolog
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107094
VEGA: 19
Homologene: 22370
Eprs1
Name: glutamyl-prolyl-tRNA synthetase 1
Synonyms: Qprs, 3010002K18Rik, 2410081F06Rik, Eprs
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 107508
HGNC: HGNC:3418
Homologene: 5870
Tasp1
Name: taspase, threonine aspartase 1
Synonyms: 4930485D02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75812
Homologene: 9795
Pkn2
Name: protein kinase N2
Synonyms: Prkcl2, 6030436C20Rik, PRK2, Stk7
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109333
HGNC: HGNC:9406
Homologene: 2054
Eif3k
Name: eukaryotic translation initiation factor 3, subunit K
Synonyms: eIF3K, Eif3s12, 1200009C21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73830
Homologene: 8292
Nsmaf
Name: neutral sphingomyelinase (N-SMase) activation associated factor
Synonyms: Fan, factor associated with N-SMase activation
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18201
HGNC: HGNC:8017
Homologene: 2652
Cyp51
Name: cytochrome P450, family 51
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13121
HGNC: HGNC:2649
Homologene: 55488
Bsx
Name: brain specific homeobox
Synonyms: Bsx1a, Bsx1b
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244813
Homologene: 65347
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, LOC381026, 9330188B09Rik, D630001M17Rik, 4921513O20Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66725
Homologene: 18982
Supt6
Name: SPT6, histone chaperone and transcription elongation factor
Synonyms: Supt6h, 5131400N11Rik, SPT6
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20926
Homologene: 40661
Tnc
Name: tenascin C
Synonyms: hexabrachion, C130033P17Rik, cytotactin, TN-C, tenascin-C, Hxb, TN
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21923
HGNC: HGNC:5318
Homologene: 55636
Arnt
Name: aryl hydrocarbon receptor nuclear translocator
Synonyms: ESTM42, bHLHe2, Hif1b, D3Ertd557e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11863
HGNC: HGNC:700
Homologene: 1261
Igf2r
Name: insulin-like growth factor 2 receptor
Synonyms: IGF-II/CI-MPR, CI-MPR, mannose-6-phosphate receptor, cation independent, M6P/IGF2R, Mpr300, CD222
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16004
HGNC: HGNC:5467
Homologene: 676
Vav2
Name: vav 2 oncogene
Synonyms: 2810040F13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22325
Homologene: 2530
Glis2
Name: GLIS family zinc finger 2
Synonyms: Nkl
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 83396
Homologene: 12821
Tmem131l
Name: transmembrane 131 like
Synonyms: D930015E06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229473
Homologene: 9057
Retnlb
Name: resistin like beta
Synonyms: 9030012B21Rik, Relmb, RELMbeta, Xcp3, Fizz2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 57263
VEGA: 16
Homologene: 10735
Sycp2l
Name: synaptonemal complex protein 2-like
Synonyms: EG621792, Gm40956, LOC218175
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 637277
Homologene: 52882
Depdc1a
Name: DEP domain containing 1a
Synonyms: 5830484J08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76131
Homologene: 9834
Stk32a
Name: serine/threonine kinase 32A
Synonyms: A930015B13Rik, YANK1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 269019
VEGA: 18
Homologene: 65357
Evc2
Name: EvC ciliary complex subunit 2
Synonyms: Ellis van Creveld syndrome 2, limbin, Lbn
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68525
Homologene: 17117
Vmn1r50
Name: vomeronasal 1 receptor 50
Synonyms: VN2, V1rb1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113852
Homologene: 113975
Aox2
Name: aldehyde oxidase 2
Synonyms: Aox3l1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 213043
Homologene: 84622
Ccdc168
Name: coiled-coil domain containing 168
Synonyms: Gm8251
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 102636082
VEGA: 1
Homologene: 141149
Col9a1
Name: collagen, type IX, alpha 1
Synonyms: Col9a-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12839
HGNC: HGNC:2217
Homologene: 1393
Or4f7
Name: olfactory receptor family 4 subfamily F member 7
Synonyms: Olfr1303, MOR245-7, GA_x6K02T2Q125-72882187-72881249, MOR245-7, Olfr276, GA_x6K02T2N82Q-3465-3764, MOR245-28_p
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258397
Homologene: 88429
Grik1
Name: glutamate receptor, ionotropic, kainate 1
Synonyms: Glur-5, GluK5, D16Ium24, D16Ium24e, A830007B11Rik, Glur5, Glurbeta1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 14805
HGNC: HGNC:4579
Homologene: 68992
Il12b
Name: interleukin 12b
Synonyms: IL-23 subunit p40, Il-12p40, IL-12 p40, Il-12b
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16160
HGNC: HGNC:5970
Homologene: 1648
Or5p73
Name: olfactory receptor family 5 subfamily P member 73
Synonyms: Olfr498, GA_x6K02T2PBJ9-10795522-10796514, MOR204-36
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258304
Homologene: 133600
Arhgap40
Name: Rho GTPase activating protein 40
Synonyms: Gm14203
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 545481
Homologene: 53500
Mrc2
Name: mannose receptor, C type 2
Synonyms: uPARAP, Endo180, novel lectin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17534
Homologene: 4408
Vmn1r181
Name: vomeronasal 1 receptor 181
Synonyms: V1rd20
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404289
Homologene: 104166
Nol4l
Name: nucleolar protein 4-like
Synonyms: 8430427H17Rik, LOC381396
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329540
Homologene: 129589
Ptpru
Name: protein tyrosine phosphatase receptor type U
Synonyms: RPTPlambda, Ptprl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Tyk2
Name: tyrosine kinase 2
Synonyms: JTK1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 54721
VEGA: 9
Homologene: 20712
Dzank1
Name: double zinc ribbon and ankyrin repeat domains 1
Synonyms: 2810039F03Rik, Ankrd64, 6330439K17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241688
Homologene: 10037
Gimd1
Name: GIMAP family P-loop NTPase domain containing 1
Synonyms: Gm5549
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 433653
Homologene: 47516
Serpinb7
Name: serine (or cysteine) peptidase inhibitor, clade B, member 7
Synonyms: megsin, 4631416M05Rik, ovalbumin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 116872
Homologene: 68363
Map3k9
Name: mitogen-activated protein kinase kinase kinase 9
Synonyms: Mlk1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 338372
VEGA: 12
HGNC: HGNC:6861
Homologene: 76377
Gbp11
Name: guanylate binding protein 11
Synonyms: Gm7141
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 634650
Homologene: 128731
Fut2
Name: fucosyltransferase 2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14344
HGNC: HGNC:4013
Homologene: 10325
Antxrl
Name: anthrax toxin receptor-like
Synonyms: 1700112N15Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239029
VEGA: 14
Homologene: 52111
Telo2
Name: telomere maintenance 2
Synonyms: 1200003M09Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71718
Homologene: 41107
Vmn1r16
Name: vomeronasal 1 receptor 16
Synonyms: V1rc29
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171202
Homologene: 123821
Gpr162
Name: G protein-coupled receptor 162
Synonyms: A-2, Grca
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14788
Homologene: 8400
Or9g8
Name: olfactory receptor family 9 subfamily G member 8
Synonyms: MOR213-5, Olfr1014, GA_x6K02T2Q125-47255337-47256254
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258562
Homologene: 83447
Or7g22
Name: olfactory receptor family 7 subfamily G member 22
Synonyms: Olfr837, GA_x6K02T2PVTD-12873838-12874776, MOR152-2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258558
HGNC: HGNC:8466
Homologene: 115507
Or6c7
Name: olfactory receptor family 6 subfamily C member 7
Synonyms: MOR111-9P, GA_x6K02T2PULF-11165842-11166815, Olfr789-ps1, MOR111-13, Olfr789
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258148
Or51f23c-ps1
Name: olfactory receptor family 51 subfamily F member 23C, pseudogene 1
Synonyms: MOR14-5, Olfr562-ps1, GA_x6K02T2PBJ9-5498153-5499103
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259090
Gm21663
Name: predicted gene, 21663
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100862349
Homologene: 69402
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 24,185,126 bp
  • T to C, chromosome 1 at 44,058,889 bp
  • T to A, chromosome 1 at 58,287,728 bp
  • G to A, chromosome 1 at 107,450,177 bp
  • C to T, chromosome 1 at 170,215,310 bp
  • C to A, chromosome 1 at 185,407,106 bp
  • G to A, chromosome 2 at 27,291,838 bp
  • T to A, chromosome 2 at 85,777,325 bp
  • T to A, chromosome 2 at 111,813,851 bp
  • A to T, chromosome 2 at 139,883,770 bp
  • G to T, chromosome 2 at 144,474,962 bp
  • C to A, chromosome 2 at 153,470,710 bp
  • A to T, chromosome 2 at 158,547,664 bp
  • A to T, chromosome 3 at 83,942,815 bp
  • G to T, chromosome 3 at 95,490,277 bp
  • T to A, chromosome 3 at 132,634,900 bp
  • C to T, chromosome 3 at 142,809,488 bp
  • T to A, chromosome 3 at 159,498,480 bp
  • CAAACTTTTAAACTT to CAAACTT, chromosome 4 at 6,416,543 bp
  • T to C, chromosome 4 at 63,970,385 bp
  • T to C, chromosome 4 at 131,772,532 bp
  • G to T, chromosome 5 at 4,099,172 bp
  • G to C, chromosome 5 at 25,942,169 bp
  • T to A, chromosome 5 at 37,393,161 bp
  • T to C, chromosome 5 at 105,326,481 bp
  • A to G, chromosome 6 at 4,906,012 bp
  • A to T, chromosome 6 at 57,323,265 bp
  • G to A, chromosome 6 at 90,108,040 bp
  • A to G, chromosome 6 at 124,859,607 bp
  • A to G, chromosome 7 at 23,985,019 bp
  • A to T, chromosome 7 at 28,972,235 bp
  • G to T, chromosome 7 at 45,650,951 bp
  • A to G, chromosome 7 at 102,782,268 bp
  • A to T, chromosome 7 at 108,465,608 bp
  • A to T, chromosome 8 at 36,613,567 bp
  • G to A, chromosome 9 at 19,137,374 bp
  • C to A, chromosome 9 at 21,108,776 bp
  • G to T, chromosome 9 at 40,874,340 bp
  • T to A, chromosome 10 at 129,487,778 bp
  • C to A, chromosome 11 at 44,410,280 bp
  • T to A, chromosome 11 at 44,410,281 bp
  • G to A, chromosome 11 at 77,974,295 bp
  • G to T, chromosome 11 at 78,222,274 bp
  • A to G, chromosome 11 at 105,340,572 bp
  • A to G, chromosome 11 at 108,014,235 bp
  • T to C, chromosome 12 at 81,773,081 bp
  • A to T, chromosome 13 at 41,146,594 bp
  • A to G, chromosome 13 at 68,575,322 bp
  • G to A, chromosome 14 at 34,071,703 bp
  • C to T, chromosome 15 at 91,673,256 bp
  • A to G, chromosome 16 at 4,611,776 bp
  • T to A, chromosome 16 at 48,818,617 bp
  • G to A, chromosome 16 at 87,935,908 bp
  • G to T, chromosome 17 at 12,691,213 bp
  • T to C, chromosome 17 at 25,105,092 bp
  • A to T, chromosome 18 at 43,313,432 bp
  • A to T, chromosome 19 at 41,890,138 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9097 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068912-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.