Strain Name:
C57BL/6J-MtgxR9162Btlr/Mmmh
Stock Number:
068943-MU
Citation ID:
RRID:MMRRC_068943-MU
Other Names:
R9162 (G1)
Major Collection:

Strain Information

Ext1
Name: exostosin glycosyltransferase 1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14042
HGNC: HGNC:3512
Homologene: 30957
Dysf
Name: dysferlin
Synonyms: 2310004N10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 26903
HGNC: HGNC:3097
Homologene: 20748
Xrn1
Name: 5'-3' exoribonuclease 1
Synonyms: Dhm2, mXrn1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 24127
Homologene: 5894
Sgsm1
Name: small G protein signaling modulator 1
Synonyms: 2410098H20Rik, D5Bwg1524e, Rutbc2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 52850
Homologene: 64485
Tmem87b
Name: transmembrane protein 87B
Synonyms: 2610301K12Rik, 2810431I02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72477
Homologene: 69513
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: trithorax Drosophila, ALL-1, Mll1, Cxxc7, Mll, HTRX1, All1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214162
HGNC: HGNC:7132
Homologene: 4338
Zmym2
Name: zinc finger, MYM-type 2
Synonyms: SCLL, MYM, RAMP, FIM, Zfp198
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 76007
VEGA: 14
Homologene: 12631
Git1
Name: GIT ArfGAP 1
Synonyms: p95Cat, Cat-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216963
HGNC: HGNC:4272
Homologene: 32204
Tank
Name: TRAF family member-associated Nf-kappa B activator
Synonyms: E430026L09Rik, I-TRAF
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21353
Homologene: 3081
Abcb8
Name: ATP-binding cassette, sub-family B member 8
Synonyms: 4833412N02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74610
HGNC: HGNC:49
Homologene: 5203
Adamts12
Name: ADAM metallopeptidase with thrombospondin type 1 motif 12
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239337
VEGA: 15
Homologene: 12808
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Tars3
Name: threonyl-tRNA synthetase 3
Synonyms: A530046H20Rik, Tarsl2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 272396
Homologene: 65036
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269700
Homologene: 28297
Syndig1l
Name: synapse differentiation inducing 1 like
Synonyms: Tmem90a, capucin, LOC238321, SynDIG2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 627191
VEGA: 12
Homologene: 82470
Kcnv1
Name: potassium channel, subfamily V, member 1
Synonyms: 2700023A03Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67498
VEGA: 15
Homologene: 22811
Plcd4
Name: phospholipase C, delta 4
Synonyms: 4921507K24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18802
HGNC: HGNC:9062
Homologene: 88782
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: b2b1554Clo, A2mr, CD91
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233651
Homologene: 2771
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: b2b1203Clo, Dnahc11, avc4, b2b1289Clo, b2b1279Clo, lrd, b2b598Clo, b2b1727Clo
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Arsi
Name: arylsulfatase i
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 545260
Homologene: 44428
Myo1g
Name: myosin IG
Synonyms: E430002D17Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 246177
Homologene: 27996
Cul9
Name: cullin 9
Synonyms: Parc, 1810035I07Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78309
Homologene: 56696
Scyl3
Name: SCY1-like 3 (S. cerevisiae)
Synonyms: Pace1, 1200016D23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240880
Homologene: 10706
Slco1a8
Name: solute carrier organic anion transporter family, member 1a8
Synonyms: Gm6614
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 625716
Homologene: 87075
Siah2
Name: siah E3 ubiquitin protein ligase 2
Synonyms: Sinh2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20439
Homologene: 21053
Slc4a11
Name: solute carrier family 4, sodium bicarbonate transporter-like, member 11
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269356
Homologene: 12931
Or7e175
Name: olfactory receptor family 7 subfamily E member 175
Synonyms: Olfr869, MOR145-6, GA_x6K02T2PVTD-13878275-13879204
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258550
HGNC: HGNC:8396
Homologene: 138312
Dcst2
Name: DC-STAMP domain containing 2
Synonyms: LOC329702
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329702
Homologene: 16951
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Pappa
Name: pregnancy-associated plasma protein A
Synonyms: PAPP-A, IGFBP-4ase, 8430414N03Rik, PAG1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18491
HGNC: HGNC:8602
Homologene: 31097
Gpr22
Name: G protein-coupled receptor 22
Synonyms: 2900068K05Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 73010
HGNC: HGNC:4477
Homologene: 18420
Spef2
Name: sperm flagellar 2
Synonyms: C230086A09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 320277
Homologene: 23371
Flnc
Name: filamin C, gamma
Synonyms: 1110055E19Rik, actin binding protein 280, Fln2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68794
HGNC: HGNC:3756
Homologene: 37481
Or5b12
Name: olfactory receptor family 5 subfamily B member 12
Synonyms: MOR202-5, Olfr1448, GA_x6K02T2RE5P-3249780-3248836
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258696
Homologene: 64904
Stat6
Name: signal transducer and activator of transcription 6
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20852
Homologene: 2373
Zfp229
Name: zinc finger protein 229
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381067
Homologene: 136287
Socs4
Name: suppressor of cytokine signaling 4
Synonyms: Socs7, 3110032M18Rik, A730004F22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67296
Homologene: 15442
Pcdhb17
Name: protocadherin beta 17
Synonyms: PcdhbQ, Pcdhb16
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93888
Homologene: 81881
A430078G23Rik
Name: RIKEN cDNA A430078G23 gene
Type: Gene
Species: Mouse
Chromosome: 8
Abcd2
Name: ATP-binding cassette, sub-family D member 2
Synonyms: adrenoleukodystrophy related, ALDR, ALDL1, ABC39
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 26874
VEGA: 15
HGNC: HGNC:66
Homologene: 55873
Msl2
Name: MSL complex subunit 2
Synonyms: Msl2l1, E130103E02Rik, Rnf184
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77853
Homologene: 10021
Hacd4
Name: 3-hydroxyacyl-CoA dehydratase 4
Synonyms: Ptplad2, 4933428I03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66775
Homologene: 12033
Or56a42-ps1
Name: olfactory receptor family 56 subfamily A member 42, pseudogene 1
Synonyms: GA_x6K02T2PBJ9-7755919-7755070, Olfr682-ps1, Olfr217-ps1, MOR40-19_p, MOR40-6P, GA_x6K02SYW8DF-188-1037
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258187
Or52e19
Name: olfactory receptor family 52 subfamily E member 19
Synonyms: ENSMUSG00000073953, Olfr596-ps1, Gm15117, GA_x6K02T2PBJ9-6019769-6019943, Olfr596
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100041187
Homologene: 121535
Tial1
Name: Tia1 cytotoxic granule-associated RNA binding protein-like 1
Synonyms: mTIAR, TIAR, 5330433G13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21843
Homologene: 87796
Ttyh3
Name: tweety family member 3
Synonyms: 2900029G13Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 78339
Homologene: 18431
Abhd17a
Name: abhydrolase domain containing 17A
Synonyms: Fam108a, D10Bwg1364e, 1700013O15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216169
Homologene: 50272
Lnp1
Name: leukemia NUP98 fusion partner 1
Synonyms: Gm19797
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 100503609
Homologene: 67109
Spata31e1
Name: spermatogenesis associated 31 subfamily E member 1
Synonyms: Gm30302
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 102632152
VEGA: 13
Homologene: 141176
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 74,562,203 bp
  • C to A, chromosome 1 at 163,946,322 bp
  • C to A, chromosome 2 at 61,650,088 bp
  • C to T, chromosome 2 at 128,839,230 bp
  • T to A, chromosome 2 at 130,692,294 bp
  • C to A, chromosome 3 at 58,691,683 bp
  • C to A, chromosome 3 at 89,366,781 bp
  • T to A, chromosome 4 at 65,204,803 bp
  • T to A, chromosome 4 at 88,419,780 bp
  • A to G, chromosome 5 at 24,406,734 bp
  • A to T, chromosome 5 at 113,282,711 bp
  • A to G, chromosome 5 at 121,306,979 bp
  • G to A, chromosome 5 at 140,636,065 bp
  • T to C, chromosome 6 at 29,455,861 bp
  • C to T, chromosome 6 at 84,112,233 bp
  • T to A, chromosome 6 at 141,993,727 bp
  • G to A, chromosome 7 at 65,682,770 bp
  • A to T, chromosome 7 at 103,309,720 bp
  • A to T, chromosome 7 at 105,128,247 bp
  • A to C, chromosome 7 at 105,765,525 bp
  • A to G, chromosome 7 at 128,448,691 bp
  • T to C, chromosome 8 at 3,364,645 bp
  • T to C, chromosome 8 at 44,951,315 bp
  • A to G, chromosome 9 at 20,129,161 bp
  • T to C, chromosome 9 at 44,848,066 bp
  • T to C, chromosome 9 at 96,033,607 bp
  • T to C, chromosome 9 at 101,101,729 bp
  • T to C, chromosome 9 at 108,110,684 bp
  • T to C, chromosome 10 at 80,586,743 bp
  • C to T, chromosome 10 at 127,605,499 bp
  • A to G, chromosome 10 at 127,651,220 bp
  • T to A, chromosome 11 at 6,510,897 bp
  • T to A, chromosome 11 at 77,505,505 bp
  • A to G, chromosome 12 at 31,708,725 bp
  • A to G, chromosome 12 at 84,680,517 bp
  • C to T, chromosome 12 at 118,027,516 bp
  • T to G, chromosome 13 at 49,785,834 bp
  • T to A, chromosome 14 at 47,290,844 bp
  • T to A, chromosome 14 at 56,925,904 bp
  • T to G, chromosome 15 at 9,601,931 bp
  • A to G, chromosome 15 at 11,311,635 bp
  • T to C, chromosome 15 at 45,109,054 bp
  • G to A, chromosome 15 at 53,345,108 bp
  • A to G, chromosome 15 at 91,174,723 bp
  • A to T, chromosome 16 at 56,917,481 bp
  • T to C, chromosome 17 at 21,745,514 bp
  • A to C, chromosome 17 at 46,526,603 bp
  • T to C, chromosome 18 at 37,487,115 bp
  • T to C, chromosome 18 at 60,917,497 bp
  • A to T, chromosome 19 at 12,919,660 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9162 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068943-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.