Strain Name:
C57BL/6J-MtgxR9196Btlr/Mmmh
Stock Number:
068955-MU
Citation ID:
RRID:MMRRC_068955-MU
Other Names:
R9196 (G1)
Major Collection:

Strain Information

Myo10
Name: myosin X
Synonyms: myosin-X, D15Ertd600e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17909
HGNC: HGNC:7593
Homologene: 36328
Fzd6
Name: frizzled class receptor 6
Synonyms: Fz6, rst
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14368
VEGA: 15
HGNC: HGNC:4044
Homologene: 2617
Pcbp3
Name: poly(rC) binding protein 3
Synonyms: AlphaCP-3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 59093
HGNC: HGNC:8651
Homologene: 23233
Rtn4
Name: reticulon 4
Synonyms: 1110020G17Rik, NgA, C130026I10Rik, Nogo-A, Nogo-B, NOGO
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68585
Homologene: 10743
Nol10
Name: nucleolar protein 10
Synonyms: LOC217431
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217431
VEGA: 12
Homologene: 5998
Cc2d1b
Name: coiled-coil and C2 domain containing 1B
Synonyms: A830039B04Rik, Freud2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 319965
Homologene: 70951
Abcb8
Name: ATP-binding cassette, sub-family B member 8
Synonyms: 4833412N02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74610
HGNC: HGNC:49
Homologene: 5203
Ythdc2
Name: YTH domain containing 2
Synonyms: 3010002F02Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240255
Homologene: 11265
Skic2
Name: SKI2 subunit of superkiller complex
Synonyms: 4930534J06Rik, Skiv2l, Ski2w
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 108077
Homologene: 123971
Hibadh
Name: 3-hydroxyisobutyrate dehydrogenase
Synonyms: 6430402H10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 58875
HGNC: HGNC:4907
Homologene: 15088
Reln
Name: reelin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19699
HGNC: HGNC:9957
Homologene: 3699
Adgrf5
Name: adhesion G protein-coupled receptor F5
Synonyms: Gpr116, 8430401C09Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224792
VEGA: 17
Homologene: 9065
Celsr1
Name: cadherin, EGF LAG seven-pass G-type receptor 1
Synonyms: Scy, Crsh, Adgrc1, crash
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12614
VEGA: 15
HGNC: HGNC:1850
Homologene: 7665
Ndst4
Name: N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
Synonyms: 4930439H17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 64580
Homologene: 11208
Nlrp9a
Name: NLR family, pyrin domain containing 9A
Synonyms: Nalp-theta, Nalp9a, D7Ertd565e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233001
Homologene: 116072
Uspl1
Name: ubiquitin specific peptidase like 1
Synonyms: E430026A01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231915
Homologene: 4235
Unc79
Name: unc-79 homolog
Synonyms: 9030205A07Rik, Mlca3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217843
Homologene: 41397
Duox1
Name: dual oxidase 1
Synonyms: LNOX1, 9930101G15Rik, THOX1, NOXEF1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99439
HGNC: HGNC:3062
Homologene: 68136
Sorbs2
Name: sorbin and SH3 domain containing 2
Synonyms: 2010203O03Rik, 9430041O17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234214
Homologene: 83295
Grm5
Name: glutamate receptor, metabotropic 5
Synonyms: 6430542K11Rik, Glu5R, mGluR5, Gprc1e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 108071
HGNC: HGNC:4597
Homologene: 37354
Neto1
Name: neuropilin (NRP) and tolloid (TLL)-like 1
Synonyms: C130005O10Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 246317
VEGA: 18
Homologene: 16367
Abtb2
Name: ankyrin repeat and BTB domain containing 2
Synonyms: BPOZ-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99382
Homologene: 15904
Dsel
Name: dermatan sulfate epimerase-like
Synonyms: 9330132E09Rik, DS-epi2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 319901
Homologene: 12964
Itprid1
Name: ITPR interacting domain containing 1
Synonyms: Ccdc129, D530004J12Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232016
Homologene: 52344
Jmy
Name: junction-mediating and regulatory protein
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 57748
VEGA: 13
Homologene: 10955
Krt23
Name: keratin 23
Synonyms: Krt1-23, K23, CK23
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 94179
HGNC: HGNC:6438
Homologene: 9172
Xrra1
Name: X-ray radiation resistance associated 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 446101
Homologene: 19547
Inpp1
Name: inositol polyphosphate-1-phosphatase
Synonyms: 2300002C06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16329
HGNC: HGNC:6071
Homologene: 1655
Col8a1
Name: collagen, type VIII, alpha 1
Synonyms: Col8a-1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12837
HGNC: HGNC:2215
Homologene: 22423
Lrrc23
Name: leucine rich repeat containing 23
Synonyms: Lrpb7, 4921537K05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16977
Homologene: 5082
Trpc4
Name: transient receptor potential cation channel, subfamily C, member 4
Synonyms: Trp4, Trrp4, CCE1, STRPC4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22066
Homologene: 22955
Zfp764l1
Name: zinc finger protein 764 like 1
Synonyms: E430018J23Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101604
Homologene: 138471
Galntl6
Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
Synonyms: 4930431L04Rik, 1700021K10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 270049
Homologene: 65137
Cenpn
Name: centromere protein N
Synonyms: 2610510J17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72155
Homologene: 12450
Pcdhb20
Name: protocadherin beta 20
Synonyms: Pcdhb14, PcdhbT
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93891
HGNC: HGNC:8685
Homologene: 134303
Hepacam
Name: hepatocyte cell adhesion molecule
Synonyms: Glialcam, 2900042E01Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72927
Homologene: 17652
Hs3st1
Name: heparan sulfate (glucosamine) 3-O-sulfotransferase 1
Synonyms: D5Wsu110e, 3-OST
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 15476
HGNC: HGNC:5194
Homologene: 3751
Zfp606
Name: zinc finger protein 606
Synonyms: 2410022M24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67370
Homologene: 23514
Cfap54
Name: cilia and flagella associated protein 54
Synonyms: LOC380653, Gm872, 4930485B16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 380654
Homologene: 133438
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 52,794,619 bp
  • C to T, chromosome 1 at 111,860,133 bp
  • A to T, chromosome 2 at 103,683,302 bp
  • T to C, chromosome 2 at 122,320,208 bp
  • A to G, chromosome 3 at 54,222,451 bp
  • C to T, chromosome 3 at 125,724,736 bp
  • T to A, chromosome 4 at 108,627,937 bp
  • A to C, chromosome 5 at 22,152,473 bp
  • T to C, chromosome 5 at 24,400,646 bp
  • T to A, chromosome 5 at 39,614,619 bp
  • T to C, chromosome 5 at 149,214,539 bp
  • C to T, chromosome 6 at 52,548,880 bp
  • A to T, chromosome 6 at 55,975,628 bp
  • T to C, chromosome 6 at 124,778,226 bp
  • T to A, chromosome 7 at 12,494,008 bp
  • T to A, chromosome 7 at 26,558,733 bp
  • T to C, chromosome 7 at 88,074,310 bp
  • T to C, chromosome 7 at 99,914,492 bp
  • T to C, chromosome 7 at 127,391,589 bp
  • A to G, chromosome 8 at 45,805,827 bp
  • G to T, chromosome 8 at 57,962,427 bp
  • G to A, chromosome 8 at 116,931,605 bp
  • A to T, chromosome 9 at 37,367,756 bp
  • A to G, chromosome 10 at 76,785,169 bp
  • A to G, chromosome 10 at 93,037,891 bp
  • T to C, chromosome 11 at 29,708,471 bp
  • A to T, chromosome 11 at 99,481,029 bp
  • A to G, chromosome 12 at 17,405,315 bp
  • A to G, chromosome 12 at 103,112,354 bp
  • T to A, chromosome 13 at 93,464,701 bp
  • T to A, chromosome 15 at 25,805,630 bp
  • C to A, chromosome 15 at 39,031,707 bp
  • T to G, chromosome 15 at 39,031,708 bp
  • G to T, chromosome 15 at 86,033,085 bp
  • A to T, chromosome 16 at 57,627,367 bp
  • T to C, chromosome 17 at 34,849,901 bp
  • T to C, chromosome 17 at 43,445,104 bp
  • T to A, chromosome 18 at 37,504,971 bp
  • T to A, chromosome 18 at 44,855,397 bp
  • A to T, chromosome 18 at 86,395,840 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9196 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068955-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.