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Strain Name:
C57BL/6J-MtgxR9037Btlr/Mmmh
Stock Number:
068969-MU
Citation ID:
RRID:MMRRC_068969-MU
Other Names:
R9037 (G1)
Major Collection:

Strain Information

Ptf1a
Name: pancreas specific transcription factor, 1a
Synonyms: PTF1-p48, bHLHa29
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19213
Homologene: 10304
Sox9
Name: SRY (sex determining region Y)-box 9
Synonyms: 2010306G03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20682
Homologene: 294
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Acf7, Aclp7, trabeculin alpha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11426
Homologene: 136191
Slc2a1
Name: solute carrier family 2 (facilitated glucose transporter), member 1
Synonyms: Glut-1, Glut1, M100200, Rgsc200
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20525
Homologene: 68520
Pepd
Name: peptidase D
Synonyms: Pep-4, peptidase D, Pep4, dal
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18624
HGNC: HGNC:8840
Homologene: 239
Aco2
Name: aconitase 2, mitochondrial
Synonyms: Aco3, Aco-2, D10Wsu183e, Irp1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 11429
HGNC: HGNC:118
Homologene: 856
Trappc8
Name: trafficking protein particle complex 8
Synonyms: 5033403J15Rik, D030074E01Rik, Trs85
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 75964
VEGA: 18
Homologene: 40993
Ctbp1
Name: C-terminal binding protein 1
Synonyms: D4S115h, D5H4S115, BARS, D5H4S115E, CtBP1-S, CtBP1-L, CtBP3/BARS
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13016
HGNC: HGNC:2494
Homologene: 1015
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: A630086P08Rik, opm, b2b327Clo
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 207304
VEGA: 12
Homologene: 9115
Usp24
Name: ubiquitin specific peptidase 24
Synonyms: 2810030C21Rik, 2700066K03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329908
Homologene: 35420
Pold1
Name: polymerase (DNA directed), delta 1, catalytic subunit
Synonyms: 125kDa
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18971
HGNC: HGNC:9175
Homologene: 2014
Hk2
Name: hexokinase 2
Synonyms: HKII
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 15277
HGNC: HGNC:4923
Homologene: 37273
Polr1d
Name: polymerase (RNA) I polypeptide D
Synonyms: mRPA16, 16kDa, 1110003G10Rik, Rpo1-3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20018
Homologene: 22239
Bcar1
Name: breast cancer anti-estrogen resistance 1
Synonyms: p130Cas, Cas, Crkas
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12927
HGNC: HGNC:971
Homologene: 7674
Adcy1
Name: adenylate cyclase 1
Synonyms: AC1, I-AC, D11Bwg1392e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 432530
HGNC: HGNC:232
Homologene: 41419
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Igsf9
Name: immunoglobulin superfamily, member 9
Synonyms: NRT1, Dasm1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 93842
Homologene: 10815
Klk12
Name: kallikrein related-peptidase 12
Synonyms: KLK-L5, 2310008B01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69511
HGNC: HGNC:6360
Homologene: 44690
Zfp105
Name: zinc finger protein 105
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22646
Homologene: 2568
Pnpla6
Name: patatin-like phospholipase domain containing 6
Synonyms: Swiss-cheese, MSws, Nte
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 50767
Homologene: 21333
Ints2
Name: integrator complex subunit 2
Synonyms: 2810417D08Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70422
Homologene: 10801
Mtmr9
Name: myotubularin related protein 9
Synonyms: LIP-STYX, MTMR8, 9430075G12Rik, mMTMH3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 210376
VEGA: 14
Homologene: 9148
Ift172
Name: intraflagellar transport 172
Synonyms: wim, 4930553F24Rik, avc1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67661
Homologene: 15202
Anapc4
Name: anaphase promoting complex subunit 4
Synonyms: 2610306D21Rik, APC4, D5Ertd249e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 52206
Homologene: 40873
P2rx6
Name: purinergic receptor P2X, ligand-gated ion channel, 6
Synonyms: P2xm, P2rxl1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 18440
HGNC: HGNC:8538
Homologene: 3975
Cacna2d2
Name: calcium channel, voltage-dependent, alpha 2/delta subunit 2
Synonyms: a2d2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56808
HGNC: HGNC:1400
Homologene: 4400
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: Mdnah5, b2b1154Clo, b2b1134Clo, b2b1537Clo, b2b1565Clo, Dnahc5, b2b3491Clo
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Synonyms: 9430028L06Rik, 9030411M15Rik, Fam38b2, Piezo2, Fam38b
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 667742
Homologene: 49695
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, LOC381317, LOC269160, A930037M10Rik, Ushrn, Ush2a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Trpv2
Name: transient receptor potential cation channel, subfamily V, member 2
Synonyms: Vrl1, OTRPC2, VRL-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22368
Homologene: 7993
Vwa7
Name: von Willebrand factor A domain containing 7
Synonyms: G7c, D17H6S56E-3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 27762
Homologene: 11895
Coro1a
Name: coronin, actin binding protein 1A
Synonyms: p57, coronin 1, Clabp, Lmb3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12721
HGNC: HGNC:2252
Homologene: 6545
Psma8
Name: proteasome subunit alpha 8
Synonyms: 2410072D24Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 73677
VEGA: 18
Homologene: 2086
Gm11639
Name: predicted gene 11639
Synonyms: Gm11639, Efcab15
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 105242472
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22635
Homologene: 124417
Ttc39a
Name: tetratricopeptide repeat domain 39A
Synonyms: 4922503N01Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230603
Homologene: 17739
Rasal3
Name: RAS protein activator like 3
Synonyms: A430107D22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320484
Homologene: 18901
Slc15a2
Name: solute carrier family 15 (H+/peptide transporter), member 2
Synonyms: Pept2, 8430408C16Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 57738
Homologene: 56912
Mpo
Name: myeloperoxidase
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17523
HGNC: HGNC:7218
Homologene: 55450
Afap1l2
Name: actin filament associated protein 1-like 2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226250
Homologene: 13057
Mpeg1
Name: macrophage expressed gene 1
Synonyms: Mpg-1, MPS1, Perforin-2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 17476
VEGA: 19
Homologene: 11216
Ranbp6
Name: RAN binding protein 6
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240614
HGNC: HGNC:9851
Homologene: 18935
Ablim3
Name: actin binding LIM protein family, member 3
Synonyms: D930036B08Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 319713
VEGA: 18
Homologene: 69175
Zfp788
Name: zinc finger protein 788
Synonyms: 2810426N06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67607
Homologene: 137363
Pcdhb12
Name: protocadherin beta 12
Synonyms: Pcdhb5F, PcdhbL, Pcdh3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93883
HGNC: HGNC:8690
Homologene: 87126
Ano8
Name: anoctamin 8
Synonyms: Tmem16h
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382014
Homologene: 124473
Colq
Name: collagen like tail subunit of asymmetric acetylcholinesterase
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 382864
HGNC: HGNC:2226
Serpinb6b
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6b
Synonyms: Spi12, NK13, ovalbumin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20708
HGNC: HGNC:8950
Homologene: 22633
Or5ak25
Name: olfactory receptor family 5 subfamily AK member 25
Synonyms: GA_x6K02T2Q125-46915844-46914897, MOR203-3, Olfr995
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258426
Homologene: 105170
Cyp2c55
Name: cytochrome P450, family 2, subfamily c, polypeptide 55
Synonyms: 2010318C06Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72082
HGNC: HGNC:2620
Homologene: 133567
Spata31e4
Name: spermatogenesis associated 31 subfamily E member 4
Synonyms: Gm8765
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 667693
Homologene: 134512
Or8k3
Name: olfactory receptor family 8 subfamily K member 3
Synonyms: GA_x6K02T2Q125-47703682-47702723, MOR188-3, Olfr1047
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259014
Homologene: 133664
Pde3a
Name: phosphodiesterase 3A, cGMP inhibited
Synonyms: A930022O17Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54611
HGNC: HGNC:8778
Homologene: 708
Or51b6b
Name: olfactory receptor family 51 subfamily B member 6B
Synonyms: GA_x6K02T2PBJ9-6384836-6383883, MOR1-4, Olfr623
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259126
Homologene: 133591
Or4a73
Name: olfactory receptor family 4 subfamily A member 73
Synonyms: GA_x6K02T2Q125-51034790-51033846, MOR231-9, Olfr1246
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258788
Homologene: 74246
Esp36
Name: exocrine gland secreted peptide 36
Synonyms: Gm20408
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 100126765
Rnf146
Name: ring finger protein 146
Synonyms: 2610509H23Rik, Iduna
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 68031
Homologene: 12227
Preb
Name: prolactin regulatory element binding
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 50907
HGNC: HGNC:9356
Homologene: 40877
Gulp1
Name: GULP, engulfment adaptor PTB domain containing 1
Synonyms: 5730529O06Rik, GULP, Ced6, 3110030A04Rik, CED-6
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70676
Homologene: 9467
Gast
Name: gastrin
Synonyms: GAS
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14459
HGNC: HGNC:4164
Homologene: 628
Mal2
Name: mal, T cell differentiation protein 2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105853
VEGA: 15
Homologene: 14167
Mgat1
Name: mannoside acetylglucosaminyltransferase 1
Synonyms: Mgat-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17308
HGNC: HGNC:7044
Homologene: 1804
Ly6c1
Name: lymphocyte antigen 6 family member C1
Synonyms: Ly-6C, Ly6c
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17067
Homologene: 113718
Gm5849
Name: predicted gene 5849
Type: Gene
Species: Mouse
Chromosome: 3
Ppif
Name: peptidylprolyl isomerase F (cyclophilin F)
Synonyms: CypD, CyP-F, CyP-D, mitochondrial Cyclophilin D
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105675
HGNC: HGNC:9259
Homologene: 38696
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 44,754,364 bp
  • T to C, chromosome 1 at 172,484,514 bp
  • A to T, chromosome 1 at 188,263,290 bp
  • A to G, chromosome 2 at 19,446,225 bp
  • T to C, chromosome 2 at 85,438,795 bp
  • G to T, chromosome 2 at 86,228,698 bp
  • C to T, chromosome 2 at 89,590,707 bp
  • T to G, chromosome 3 at 90,777,848 bp
  • T to C, chromosome 4 at 88,683,427 bp
  • A to G, chromosome 4 at 106,379,054 bp
  • A to G, chromosome 4 at 109,442,784 bp
  • T to C, chromosome 4 at 119,136,297 bp
  • T to C, chromosome 4 at 123,471,725 bp
  • T to C, chromosome 5 at 30,959,246 bp
  • T to C, chromosome 5 at 31,263,056 bp
  • T to A, chromosome 5 at 33,267,008 bp
  • C to A, chromosome 5 at 52,864,501 bp
  • A to G, chromosome 5 at 137,454,316 bp
  • A to T, chromosome 5 at 147,078,680 bp
  • T to A, chromosome 6 at 82,743,358 bp
  • C to A, chromosome 6 at 141,471,106 bp
  • A to T, chromosome 7 at 35,020,973 bp
  • C to T, chromosome 7 at 41,648,891 bp
  • T to C, chromosome 7 at 43,769,715 bp
  • T to C, chromosome 7 at 44,538,915 bp
  • T to A, chromosome 7 at 103,661,175 bp
  • A to C, chromosome 7 at 126,700,600 bp
  • A to T, chromosome 8 at 3,542,379 bp
  • A to G, chromosome 8 at 71,484,444 bp
  • A to C, chromosome 8 at 111,720,890 bp
  • A to G, chromosome 9 at 107,509,196 bp
  • A to G, chromosome 9 at 122,929,771 bp
  • T to C, chromosome 10 at 29,347,680 bp
  • A to G, chromosome 11 at 7,137,325 bp
  • T to G, chromosome 11 at 49,261,429 bp
  • A to T, chromosome 11 at 62,584,405 bp
  • G to A, chromosome 11 at 86,215,704 bp
  • A to G, chromosome 11 at 87,797,731 bp
  • A to G, chromosome 11 at 100,336,610 bp
  • A to G, chromosome 11 at 104,912,965 bp
  • A to G, chromosome 11 at 112,784,824 bp
  • T to C, chromosome 12 at 8,016,501 bp
  • T to C, chromosome 12 at 51,785,882 bp
  • G to T, chromosome 13 at 32,978,015 bp
  • A to G, chromosome 13 at 50,702,908 bp
  • T to C, chromosome 14 at 25,694,404 bp
  • C to A, chromosome 14 at 31,557,787 bp
  • T to A, chromosome 14 at 63,524,083 bp
  • A to T, chromosome 15 at 28,247,958 bp
  • A to G, chromosome 15 at 54,571,543 bp
  • C to A, chromosome 15 at 75,045,451 bp
  • C to G, chromosome 15 at 81,872,419 bp
  • A to G, chromosome 16 at 17,570,443 bp
  • A to T, chromosome 16 at 36,762,363 bp
  • C to A, chromosome 17 at 32,395,120 bp
  • T to C, chromosome 17 at 35,017,292 bp
  • C to T, chromosome 17 at 38,418,949 bp
  • T to C, chromosome 17 at 45,639,431 bp
  • G to T, chromosome 18 at 14,721,194 bp
  • A to G, chromosome 18 at 20,828,482 bp
  • A to C, chromosome 18 at 37,436,176 bp
  • T to A, chromosome 18 at 61,818,995 bp
  • T to A, chromosome 18 at 63,092,831 bp
  • T to A, chromosome 19 at 12,461,826 bp
  • T to C, chromosome 19 at 29,812,917 bp
  • T to A, chromosome 19 at 39,042,093 bp
  • A to T, chromosome 19 at 56,929,971 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9037 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068969-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.