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Strain Name:
C57BL/6J-MtgxR9210Btlr/Mmmh
Stock Number:
068983-MU
Citation ID:
RRID:MMRRC_068983-MU
Other Names:
R9210 (G1)
Major Collection:

Strain Information

Ptprz1
Name: protein tyrosine phosphatase receptor type Z, polypeptide 1
Synonyms: DSD-1-PG, phosphacan, PTPzeta, PTPbeta, Rptpbeta, Ptpz, Ptprz, RPTPz
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Mta3
Name: metastasis associated 3
Synonyms: 1110002J22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 116871
Homologene: 14282
Chd1
Name: chromodomain helicase DNA binding protein 1
Synonyms: 4930525N21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12648
HGNC: HGNC:1915
Homologene: 68174
Ccdc91
Name: coiled-coil domain containing 91
Synonyms: 1700086G08Rik, 1810060J02Rik, p56
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67015
Homologene: 10131
Ercc6
Name: excision repair cross-complementing rodent repair deficiency, complementation group 6
Synonyms: CS group B correcting gene, CSB, C130058G22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 319955
VEGA: 14
HGNC: HGNC:3438
Homologene: 133552
Rrp15
Name: ribosomal RNA processing 15 homolog
Synonyms: 5430437H21Rik, 2810430M08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67223
Homologene: 32293
Zfp280d
Name: zinc finger protein 280D
Synonyms: Suhw4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235469
Homologene: 17151
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 9,566,811 bp
  • A to T, chromosome 1 at 24,461,474 bp
  • A to G, chromosome 1 at 58,476,536 bp
  • T to C, chromosome 1 at 65,252,560 bp
  • G to A, chromosome 1 at 74,920,408 bp
  • C to T, chromosome 1 at 81,241,327 bp
  • G to A, chromosome 1 at 86,352,517 bp
  • A to T, chromosome 1 at 87,957,313 bp
  • A to G, chromosome 1 at 152,766,852 bp
  • G to C, chromosome 1 at 186,739,725 bp
  • A to T, chromosome 1 at 188,784,669 bp
  • T to C, chromosome 2 at 37,487,140 bp
  • T to C, chromosome 2 at 101,644,507 bp
  • A to T, chromosome 2 at 180,472,478 bp
  • T to G, chromosome 3 at 29,153,594 bp
  • T to A, chromosome 3 at 54,266,320 bp
  • C to A, chromosome 3 at 87,849,348 bp
  • A to T, chromosome 3 at 109,872,317 bp
  • G to T, chromosome 4 at 43,536,119 bp
  • A to T, chromosome 4 at 119,178,509 bp
  • A to G, chromosome 4 at 137,562,479 bp
  • A to G, chromosome 4 at 138,325,967 bp
  • A to G, chromosome 4 at 145,899,228 bp
  • C to T, chromosome 5 at 8,955,591 bp
  • T to C, chromosome 5 at 34,440,137 bp
  • T to C, chromosome 5 at 98,947,474 bp
  • C to A, chromosome 5 at 112,349,361 bp
  • T to A, chromosome 5 at 148,077,314 bp
  • A to G, chromosome 6 at 23,050,494 bp
  • T to C, chromosome 6 at 23,075,768 bp
  • C to T, chromosome 6 at 34,798,242 bp
  • A to G, chromosome 6 at 57,662,365 bp
  • G to T, chromosome 6 at 68,939,902 bp
  • T to A, chromosome 6 at 110,645,908 bp
  • T to C, chromosome 6 at 119,480,674 bp
  • A to G, chromosome 6 at 147,606,900 bp
  • A to T, chromosome 7 at 48,552,644 bp
  • C to A, chromosome 7 at 107,954,810 bp
  • C to A, chromosome 7 at 128,268,767 bp
  • T to C, chromosome 8 at 21,997,390 bp
  • T to A, chromosome 8 at 33,574,291 bp
  • T to C, chromosome 8 at 68,461,589 bp
  • T to C, chromosome 8 at 83,435,914 bp
  • T to C, chromosome 8 at 95,557,246 bp
  • A to T, chromosome 9 at 19,647,146 bp
  • A to G, chromosome 9 at 62,850,691 bp
  • G to A, chromosome 9 at 67,759,746 bp
  • A to G, chromosome 9 at 72,362,507 bp
  • A to T, chromosome 9 at 90,205,130 bp
  • T to C, chromosome 9 at 101,185,976 bp
  • A to G, chromosome 10 at 76,451,331 bp
  • A to T, chromosome 10 at 79,992,539 bp
  • T to A, chromosome 11 at 6,396,277 bp
  • C to T, chromosome 11 at 60,189,391 bp
  • G to T, chromosome 11 at 97,238,221 bp
  • G to A, chromosome 12 at 69,197,828 bp
  • C to A, chromosome 12 at 83,988,077 bp
  • A to T, chromosome 12 at 85,280,046 bp
  • A to C, chromosome 13 at 11,829,674 bp
  • A to C, chromosome 13 at 30,946,875 bp
  • T to A, chromosome 14 at 32,569,865 bp
  • T to C, chromosome 14 at 44,001,950 bp
  • G to A, chromosome 14 at 55,542,450 bp
  • T to C, chromosome 14 at 103,055,090 bp
  • A to T, chromosome 16 at 18,624,211 bp
  • A to C, chromosome 16 at 93,630,239 bp
  • T to G, chromosome 17 at 15,730,505 bp
  • T to C, chromosome 17 at 25,824,498 bp
  • A to G, chromosome 17 at 67,855,435 bp
  • T to G, chromosome 17 at 80,268,909 bp
  • A to T, chromosome 17 at 83,708,417 bp
  • T to C, chromosome 18 at 22,522,332 bp
  • T to C, chromosome 18 at 89,046,162 bp
  • T to A, chromosome 19 at 5,341,507 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9210 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068983-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.