Strain Name:
C57BL/6J-MtgxR9161Btlr/Mmmh
Stock Number:
069022-MU
Citation ID:
RRID:MMRRC_069022-MU
Other Names:
R9161 (G1)
Major Collection:

Strain Information

Atrn
Name: attractin
Synonyms: Mgca
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11990
HGNC: HGNC:885
Homologene: 22542
Gon4l
Name: gon-4 like
Synonyms: 1500041I23Rik, 2610100B20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76022
Homologene: 13002
Clasp1
Name: CLIP associating protein 1
Synonyms: 5730583A19Rik, mCLASP1, 1700030C23Rik, CLASP1alpha, CLASP1, B130045P17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 76707
Homologene: 41024
Pik3ip1
Name: phosphoinositide-3-kinase interacting protein 1
Synonyms: 1500004A08Rik, 5830455E04Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216505
Homologene: 14166
Ckap5
Name: cytoskeleton associated protein 5
Synonyms: 3110043H24Rik, 4930432B04Rik, D730027C18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75786
Homologene: 8844
Fbxw8
Name: F-box and WD-40 domain protein 8
Synonyms: FBW6, 4930438M06Rik, FBXO29, Fbx29, FBW8
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231672
Homologene: 17731
Rsf1
Name: remodeling and spacing factor 1
Synonyms: p325, 4832420A03Rik, Hbxap, C030033M12Rik, XAP8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: Swl, Dnchc1, 9930018I23Rik, Dnec1, dynein heavy chain, retrograde transport, MAP1C, Loa
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
Mbd1
Name: methyl-CpG binding domain protein 1
Synonyms: Cxxc3, PCM1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17190
VEGA: 18
HGNC: HGNC:6916
Homologene: 8414
Taf6
Name: TATA-box binding protein associated factor 6
Synonyms: 80kDa, p80, Taf2e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 21343
Homologene: 7561
Rab3ip
Name: RAB3A interacting protein
Synonyms: Gtpat12, Rabin3, SSX2 interacting protein
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216363
VEGA: 10
Homologene: 32340
Pip4k2b
Name: phosphatidylinositol-5-phosphate 4-kinase, type II, beta
Synonyms: PI5P4Kbeta, Pip5k2b, c11
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 108083
HGNC: HGNC:8998
Homologene: 2634
Arglu1
Name: arginine and glutamate rich 1
Synonyms: 9430010O03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234023
Homologene: 9960
Erp29
Name: endoplasmic reticulum protein 29
Synonyms: Erp31, 2810446M09Rik, PDI-Db, 1200015M03Rik, Erp28
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67397
Homologene: 4963
Nrip3
Name: nuclear receptor interacting protein 3
Synonyms: D7H11orf14, A330103B05Rik, ICRFP703N2430Q5.2, ICRFP703B1614Q5.2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 78593
HGNC: HGNC:1167
Homologene: 10764
Pdgfrb
Name: platelet derived growth factor receptor, beta polypeptide
Synonyms: Pdgfr, CD140b
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 18596
HGNC: HGNC:8804
Homologene: 1960
Map2
Name: microtubule-associated protein 2
Synonyms: repro4, G1-397-34, Mtap2, MAP-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Atad2
Name: ATPase family, AAA domain containing 2
Synonyms: 2610509G12Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 70472
VEGA: 15
Homologene: 6044
Cep152
Name: centrosomal protein 152
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99100
Homologene: 37159
Map1s
Name: microtubule-associated protein 1S
Synonyms: Map8, VCY2IP1, Mtap1s, 6430517J16Rik, Bpy2ip1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 270058
Homologene: 10047
Rai1
Name: retinoic acid induced 1
Synonyms: Gt1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19377
HGNC: HGNC:9834
Homologene: 7508
Spink5
Name: serine peptidase inhibitor, Kazal type 5
Synonyms: LEKT1, 2310065D10Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 72432
Homologene: 4987
Btbd16
Name: BTB domain containing 16
Synonyms: E330040A16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330660
Homologene: 77327
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 665700
Homologene: 90772
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
Zfp990
Name: zinc finger protein 990
Synonyms: Gm13225
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 101056073
Fam135b
Name: family with sequence similarity 135, member B
Synonyms: A830008O07Rik, 1700010C24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 70363
VEGA: 15
Homologene: 66605
Nlrc5
Name: NLR family, CARD domain containing 5
Synonyms: AI451557
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 434341
Homologene: 88935
Rnf32
Name: ring finger protein 32
Synonyms: 1700009J01Rik, Lmbr2, 2700025B22Rik, 4930542N22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56874
Homologene: 10986
Cdkl4
Name: cyclin dependent kinase like 4
Synonyms: LOC381113
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381113
VEGA: 17
Homologene: 28725
Or10w1
Name: olfactory receptor family 10 subfamily W member 1
Synonyms: MOR266-6P, Olfr1490, GA_x6K02T2RE5P-3987000-3987950
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258098
Homologene: 79418
Vmn1r20
Name: vomeronasal 1 receptor 20
Synonyms: Gm5569
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 434017
Homologene: 79462
Cdh24
Name: cadherin-like 24
Synonyms: 1700040A22Rik, cadherin 14-like, EY-cadherin, ENSMUSG00000022188
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239096
VEGA: 14
Homologene: 56951
Gabrb1
Name: gamma-aminobutyric acid type A receptor subunit beta 1
Synonyms: Gabrb-1, B230208N19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14400
HGNC: HGNC:4081
Homologene: 20221
Megf6
Name: multiple EGF-like-domains 6
Synonyms: Egfl3, 2600001P17Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230971
HGNC: HGNC:3232
Homologene: 45412
Col15a1
Name: collagen, type XV, alpha 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12819
HGNC: HGNC:2192
Homologene: 1396
Or8g21
Name: olfactory receptor family 8 subfamily G member 21
Synonyms: Olfr935, GA_x6K02T2PVTD-32691280-32690354, MOR171-11
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258741
VEGA: 9
Homologene: 133683
Vmn2r120
Name: vomeronasal 2, receptor 120
Synonyms: EG224916
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224916
Tyms
Name: thymidylate synthase
Synonyms: TS
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22171
Homologene: 834
Cotl1
Name: coactosin like F-actin binding protein 1
Synonyms: 1810074P22Rik, 2010004C08Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72042
Homologene: 10898
Adprhl1
Name: ADP-ribosylhydrolase like 1
Synonyms: Arh2, D330008N11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234072
Homologene: 16311
Tbxas1
Name: thromboxane A synthase 1, platelet
Synonyms: TXS, TXAS, CYP5A1, CYP5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21391
Homologene: 130979
Galnt15
Name: polypeptide N-acetylgalactosaminyltransferase 15
Synonyms: Galntl2, 4631401E18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 78754
Homologene: 14286
Kif28
Name: kinesin family member 28
Synonyms: Gm1305, LOC383592
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 383592
Homologene: 130945
Get1
Name: guided entry of tail-anchored proteins factor 1
Synonyms: C030018G21Rik, Chd5, 5530402J05Rik, Wrb
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 71446
Homologene: 37945
Or51a10
Name: olfactory receptor family 51 subfamily A member 10
Synonyms: MOR13-6, GA_x6K02T2PBJ9-6784380-6783436, Olfr642
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258326
Homologene: 17196
Or8k16
Name: olfactory receptor family 8 subfamily K member 16
Synonyms: GA_x6K02T2Q125-47170431-47171372, MOR187-3, Olfr1008
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258866
Ehd3
Name: EH-domain containing 3
Synonyms: Ehd2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 57440
HGNC: HGNC:3244
Homologene: 81837
Vmn2r69
Name: vomeronasal 2, receptor 69
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330581
Homologene: 115466
Or12j3
Name: olfactory receptor family 12 subfamily J member 3
Synonyms: MOR252-2, GA_x6K02T2PBJ9-42523824-42522901, Olfr530
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258512
Homologene: 128384
Rd3l
Name: retinal degeneration 3-like
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217874
Homologene: 19151
Cryba4
Name: crystallin, beta A4
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12959
HGNC: HGNC:2396
Homologene: 1422
Slc4a1ap
Name: solute carrier family 4 (anion exchanger), member 1, adaptor protein
Synonyms: kanadaptin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20534
Homologene: 7543
Tcap
Name: titin-cap
Synonyms: Telethonin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21393
Homologene: 2724
Bnip5
Name: BCL2 interacting protein 5
Synonyms: 4930539E08Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 207819
Homologene: 52098
Pttg1ip
Name: pituitary tumor-transforming 1 interacting protein
Synonyms: 1810010L20Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 108705
Homologene: 3203
BC024063
Name: cDNA sequence BC024063
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 666584
VEGA: 10
Inha
Name: inhibin alpha
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16322
HGNC: HGNC:6065
Homologene: 1652
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 66,438,344 bp (GRCm38)
  • A to G, chromosome 1 at 75,507,500 bp (GRCm38)
  • A to T, chromosome 1 at 118,546,921 bp (GRCm38)
  • A to C, chromosome 1 at 179,698,679 bp (GRCm38)
  • A to G, chromosome 2 at 31,352,746 bp (GRCm38)
  • A to G, chromosome 2 at 85,689,887 bp (GRCm38)
  • A to T, chromosome 2 at 91,615,308 bp (GRCm38)
  • T to C, chromosome 2 at 125,350,350 bp (GRCm38)
  • T to A, chromosome 2 at 125,566,654 bp (GRCm38)
  • T to C, chromosome 2 at 130,935,550 bp (GRCm38)
  • A to G, chromosome 3 at 88,901,648 bp (GRCm38)
  • G to C, chromosome 4 at 47,288,200 bp (GRCm38)
  • G to T, chromosome 4 at 145,534,939 bp (GRCm38)
  • A to G, chromosome 4 at 154,267,715 bp (GRCm38)
  • A to G, chromosome 5 at 29,203,060 bp (GRCm38)
  • T to C, chromosome 5 at 30,061,042 bp (GRCm38)
  • A to G, chromosome 5 at 31,528,130 bp (GRCm38)
  • A to G, chromosome 5 at 72,029,856 bp (GRCm38)
  • A to C, chromosome 5 at 112,248,173 bp (GRCm38)
  • A to G, chromosome 5 at 118,113,662 bp (GRCm38)
  • T to C, chromosome 5 at 121,445,083 bp (GRCm38)
  • G to T, chromosome 5 at 138,179,898 bp (GRCm38)
  • A to T, chromosome 6 at 39,023,055 bp (GRCm38)
  • C to A, chromosome 6 at 57,431,774 bp (GRCm38)
  • T to A, chromosome 7 at 85,406,969 bp (GRCm38)
  • GGCG to GGCGACCGCCGCG, chromosome 7 at 97,579,906 bp (GRCm38)
  • C to A, chromosome 7 at 104,050,518 bp (GRCm38)
  • C to T, chromosome 7 at 109,766,570 bp (GRCm38)
  • C to T, chromosome 7 at 130,815,786 bp (GRCm38)
  • C to T, chromosome 7 at 140,373,076 bp (GRCm38)
  • T to A, chromosome 7 at 141,799,289 bp (GRCm38)
  • T to C, chromosome 8 at 8,683,941 bp (GRCm38)
  • T to A, chromosome 8 at 13,222,270 bp (GRCm38)
  • G to A, chromosome 8 at 70,913,606 bp (GRCm38)
  • A to C, chromosome 8 at 94,486,646 bp (GRCm38)
  • G to T, chromosome 8 at 119,822,717 bp (GRCm38)
  • A to T, chromosome 9 at 38,994,520 bp (GRCm38)
  • A to C, chromosome 10 at 77,589,653 bp (GRCm38)
  • T to A, chromosome 10 at 82,109,210 bp (GRCm38)
  • C to T, chromosome 10 at 116,914,161 bp (GRCm38)
  • G to T, chromosome 11 at 3,331,945 bp (GRCm38)
  • A to G, chromosome 11 at 60,185,856 bp (GRCm38)
  • A to G, chromosome 11 at 97,724,419 bp (GRCm38)
  • G to T, chromosome 11 at 98,384,430 bp (GRCm38)
  • A to G, chromosome 12 at 110,658,589 bp (GRCm38)
  • T to C, chromosome 12 at 111,980,319 bp (GRCm38)
  • T to A, chromosome 14 at 32,058,159 bp (GRCm38)
  • A to T, chromosome 14 at 54,638,640 bp (GRCm38)
  • A to T, chromosome 15 at 58,125,789 bp (GRCm38)
  • T to A, chromosome 15 at 71,462,568 bp (GRCm38)
  • A to T, chromosome 16 at 96,151,939 bp (GRCm38)
  • T to A, chromosome 17 at 28,909,413 bp (GRCm38)
  • A to T, chromosome 17 at 57,524,864 bp (GRCm38)
  • A to T, chromosome 17 at 73,827,485 bp (GRCm38)
  • A to G, chromosome 17 at 80,543,691 bp (GRCm38)
  • T to A, chromosome 18 at 44,014,919 bp (GRCm38)
  • T to G, chromosome 18 at 61,063,981 bp (GRCm38)
  • C to T, chromosome 18 at 74,274,721 bp (GRCm38)
  • G to A, chromosome 19 at 13,654,674 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9161 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069022-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.