Strain Name:
C57BL/6J-MtgxR9179Btlr/Mmmh
Stock Number:
069029-MU
Citation ID:
RRID:MMRRC_069029-MU
Other Names:
R9179 (G1)
Major Collection:

Strain Information

Ahdc1
Name: AT hook, DNA binding motif, containing 1
Synonyms: D030015G18Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230793
Homologene: 17144
Tnrc6a
Name: trinucleotide repeat containing 6a
Synonyms: CAGH26, Tnrc6, D130023A07Rik, 3110054G10Rik, 2010321I05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233833
Homologene: 41399
Flnb
Name: filamin, beta
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 286940
HGNC: HGNC:3755
Homologene: 37480
Xrn2
Name: 5'-3' exoribonuclease 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 24128
Homologene: 6927
Sel1l
Name: sel-1 suppressor of lin-12-like (C. elegans)
Synonyms: Sel1h
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20338
Homologene: 31286
Ppp1r12a
Name: protein phosphatase 1, regulatory subunit 12A
Synonyms: 1200015F06Rik, Mypt1, D10Ertd625e, 5730577I22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17931
VEGA: 10
HGNC: HGNC:7618
Homologene: 1855
Aspm
Name: abnormal spindle microtubule assembly
Synonyms: Sha1, Aspm, D330028K02Rik, MCPH5, Calmbp1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12316
Homologene: 7650
Dph6
Name: diphthamine biosynthesis 6
Synonyms: 5730421E18Rik, Diphthine ammonia ligase, Atpbd4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66632
Homologene: 80244
Cnot1
Name: CCR4-NOT transcription complex, subunit 1
Synonyms: 6030411K04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234594
HGNC: HGNC:7877
Homologene: 9453
Gls
Name: glutaminase
Synonyms: B230365M23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14660
HGNC: HGNC:4331
Homologene: 22726
Amotl1
Name: angiomotin-like 1
Synonyms: 4932416D09Rik, JEAP, 2310067L22Rik, 2310010G08Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 75723
Homologene: 43977
Ermard
Name: ER membrane associated RNA degradation
Synonyms: 2410011O22Rik, 2210404J11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381062
Homologene: 19936
Fgfr3
Name: fibroblast growth factor receptor 3
Synonyms: HBGFR, Fgfr-3, sam3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14184
HGNC: HGNC:3690
Homologene: 55437
Ppan
Name: peter pan homolog
Synonyms: SSF1, A230087P06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235036
Homologene: 5690
Tpcn1
Name: two pore channel 1
Synonyms: 5730403B01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 252972
Homologene: 9905
Ndufs1
Name: NADH:ubiquinone oxidoreductase core subunit S1
Synonyms: 9930026A05Rik, 5830412M15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227197
HGNC: HGNC:7707
Homologene: 3670
Kdm6b
Name: KDM1 lysine (K)-specific demethylase 6B
Synonyms: Jmjd3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216850
Homologene: 18945
Cdh23
Name: cadherin related 23 (otocadherin)
Synonyms: 4930542A03Rik, USH1D, mdfw, ahl, bob, nmf112, nmf181, nmf252, sals
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22295
Homologene: 11142
Ldb3
Name: LIM domain binding 3
Synonyms: ZASP, cypher
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 24131
VEGA: 14
Homologene: 134626
Zfyve28
Name: zinc finger, FYVE domain containing 28
Synonyms: 9630058O20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231125
Homologene: 15119
Gngt1
Name: guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
Synonyms: G(y)1, Gng1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14699
HGNC: HGNC:4411
Homologene: 7738
Rasef
Name: RAS and EF hand domain containing
Synonyms: RAB45
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242505
Homologene: 28424
Cntnap5c
Name: contactin associated protein-like 5C
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 620292
VEGA: 17
Homologene: 128806
Slc4a8
Name: solute carrier family 4 (anion exchanger), member 8
Synonyms: NDCBE, sodium bicarbonate cotransporter isoform 3 kNBC-3, KNBC-3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 59033
Homologene: 68419
Rims1
Name: regulating synaptic membrane exocytosis 1
Synonyms: RIM1, RIM1a, C030033M19Rik, RIM1alpha
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 116837
Homologene: 128399
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Cfap69
Name: cilia and flagella associated protein 69
Synonyms: A330021E22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 207686
Homologene: 11718
Vwa8
Name: von Willebrand factor A domain containing 8
Synonyms: 4932416F07Rik, 1300010F03Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219189
VEGA: 14
Homologene: 44881
F830045P16Rik
Name: RIKEN cDNA F830045P16 gene
Synonyms: Sirpb3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228592
Homologene: 136180
Itgal
Name: integrin alpha L
Synonyms: LFA-1, Cd11a, Ly-21, Ly-15
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16408
HGNC: HGNC:6148
Homologene: 1666
Gns
Name: glucosamine (N-acetyl)-6-sulfatase
Synonyms: G6S, 2610016K11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 75612
VEGA: 10
HGNC: HGNC:4422
Homologene: 1568
Plekha6
Name: pleckstrin homology domain containing, family A member 6
Synonyms: Pepp3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240753
Homologene: 135779
Or4a71
Name: olfactory receptor family 4 subfamily A member 71
Synonyms: GA_x6K02T2Q125-50972538-50971621, MOR231-4, Olfr1243
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258971
Homologene: 27317
Axl
Name: AXL receptor tyrosine kinase
Synonyms: Tyro7, Ark, Ufo
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26362
HGNC: HGNC:905
Homologene: 7583
Or1j11
Name: olfactory receptor family 1 subfamily E member 1
Synonyms: GA_x6K02T2NLDC-33116096-33117025, MOR136-3, Olfr339
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258951
Homologene: 133615
9330161L09Rik
Name: RIKEN cDNA 9330161L09 gene
Type: Gene
Species: Mouse
Chromosome: 12
Mettl21c
Name: methyltransferase 21C, AARS1 lysine
Synonyms: A530098C11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 433294
Homologene: 45916
Ankfn1
Name: ankyrin-repeat and fibronectin type III domain containing 1
Synonyms: LOC382543, nmf9, 4932411E22Rik, mWAKE
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 382543
Homologene: 34996
Rbm12
Name: RNA binding motif protein 12
Synonyms: 5730420G12Rik, SWAN, 9430070C08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75710
HGNC: HGNC:9898
Homologene: 34993
Pilrb1
Name: paired immunoglobin-like type 2 receptor beta 1
Synonyms: Fdact, Pilrb
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 170741
Homologene: 114502
Mocs1
Name: molybdenum cofactor synthesis 1
Synonyms: 3110045D15Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 56738
HGNC: HGNC:7190
Homologene: 4343
Klk1b1
Name: kallikrein 1-related peptidase b1
Synonyms: mGK-1, TK, tissue kallikrein, mK1, Klk1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16623
Homologene: 68141
Scel
Name: sciellin
Synonyms: 9230114I02Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 64929
VEGA: 14
Homologene: 2850
Pabpc1l
Name: poly(A) binding protein, cytoplasmic 1-like
Synonyms: ePAB, 1810053B01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381404
Homologene: 77989
1700013D24Rik
Name: RIKEN cDNA 1700013D24 gene
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 76921
Homologene: 135963
Catsperd
Name: cation channel sperm associated auxiliary subunit delta
Synonyms: 4933402B14Rik, Gm6095, 4921529N20Rik, Tmem146
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106757
VEGA: 17
Homologene: 51896
Ccdc102a
Name: coiled-coil domain containing 102A
Synonyms: LOC234582
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234582
Homologene: 13240
Tmem132b
Name: transmembrane protein 132B
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 208151
Homologene: 28135
Cyp3a41a
Name: cytochrome P450, family 3, subfamily a, polypeptide 41A
Synonyms: steroid inducible, Cyp3a41
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 53973
HGNC: HGNC:2638
Homologene: 133568
Dagla
Name: diacylglycerol lipase, alpha
Synonyms: Nsddr
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 269060
HGNC: HGNC:1165
Homologene: 4468
Grin2d
Name: glutamate receptor, ionotropic, NMDA2D (epsilon 4)
Synonyms: NMDAR2D, NR2D, GluRepsilon4, GluN2D
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14814
HGNC: HGNC:4588
Homologene: 648
Impa2
Name: inositol monophosphatase 2
Synonyms: 2210415D20Rik, inositol (myo)-1(or 4)-monophosphatase 2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 114663
VEGA: 18
HGNC: HGNC:6051
Homologene: 22799
2310003L06Rik
Name: RIKEN cDNA 2310003L06 gene
Type: Gene
Species: Mouse
Chromosome: 5
Cyp4f15
Name: cytochrome P450, family 4, subfamily f, polypeptide 15
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106648
Homologene: 80199
Pstpip2
Name: proline-serine-threonine phosphatase-interacting protein 2
Synonyms: cmo
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 19201
VEGA: 18
HGNC: HGNC:9581
Homologene: 69150
Vmn2r34
Name: vomeronasal 2, receptor 34
Synonyms: ENSMUSG00000070841
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100042636
Homologene: 113703
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 22,412,266 bp (GRCm38)
  • T to A, chromosome 1 at 44,009,982 bp (GRCm38)
  • T to C, chromosome 1 at 52,199,856 bp (GRCm38)
  • T to C, chromosome 1 at 63,170,115 bp (GRCm38)
  • A to G, chromosome 1 at 133,286,347 bp (GRCm38)
  • A to G, chromosome 1 at 139,476,715 bp (GRCm38)
  • T to C, chromosome 2 at 36,422,114 bp (GRCm38)
  • T to A, chromosome 2 at 89,528,150 bp (GRCm38)
  • C to T, chromosome 2 at 114,523,110 bp (GRCm38)
  • T to C, chromosome 2 at 129,472,788 bp (GRCm38)
  • T to C, chromosome 2 at 147,013,161 bp (GRCm38)
  • T to C, chromosome 2 at 156,096,543 bp (GRCm38)
  • T to C, chromosome 2 at 164,031,220 bp (GRCm38)
  • G to A, chromosome 4 at 73,744,119 bp (GRCm38)
  • T to A, chromosome 4 at 133,061,618 bp (GRCm38)
  • T to C, chromosome 4 at 143,949,724 bp (GRCm38)
  • A to T, chromosome 5 at 5,626,064 bp (GRCm38)
  • G to T, chromosome 5 at 33,729,972 bp (GRCm38)
  • A to T, chromosome 5 at 34,225,032 bp (GRCm38)
  • A to G, chromosome 5 at 87,972,031 bp (GRCm38)
  • A to G, chromosome 5 at 109,675,842 bp (GRCm38)
  • A to C, chromosome 5 at 120,541,950 bp (GRCm38)
  • A to T, chromosome 5 at 125,623,051 bp (GRCm38)
  • C to A, chromosome 5 at 137,857,395 bp (GRCm38)
  • A to T, chromosome 5 at 145,705,844 bp (GRCm38)
  • A to G, chromosome 6 at 3,994,246 bp (GRCm38)
  • T to A, chromosome 6 at 124,356,923 bp (GRCm38)
  • T to G, chromosome 7 at 7,672,724 bp (GRCm38)
  • T to C, chromosome 7 at 25,770,233 bp (GRCm38)
  • T to A, chromosome 7 at 43,969,291 bp (GRCm38)
  • A to G, chromosome 7 at 45,856,752 bp (GRCm38)
  • C to A, chromosome 7 at 46,288,461 bp (GRCm38)
  • T to C, chromosome 7 at 123,192,658 bp (GRCm38)
  • A to T, chromosome 7 at 127,306,711 bp (GRCm38)
  • A to G, chromosome 8 at 94,913,120 bp (GRCm38)
  • A to G, chromosome 8 at 95,773,426 bp (GRCm38)
  • C to A, chromosome 9 at 14,550,491 bp (GRCm38)
  • C to A, chromosome 9 at 20,891,903 bp (GRCm38)
  • C to T, chromosome 10 at 60,317,885 bp (GRCm38)
  • T to A, chromosome 10 at 108,251,921 bp (GRCm38)
  • T to C, chromosome 10 at 121,380,175 bp (GRCm38)
  • A to T, chromosome 11 at 69,406,695 bp (GRCm38)
  • C to T, chromosome 11 at 89,523,185 bp (GRCm38)
  • A to T, chromosome 12 at 91,811,952 bp (GRCm38)
  • A to C, chromosome 12 at 103,407,578 bp (GRCm38)
  • C to A, chromosome 14 at 7,887,541 bp (GRCm38)
  • A to T, chromosome 14 at 34,555,355 bp (GRCm38)
  • C to T, chromosome 14 at 79,098,361 bp (GRCm38)
  • T to C, chromosome 14 at 103,574,400 bp (GRCm38)
  • A to G, chromosome 15 at 100,791,601 bp (GRCm38)
  • T to A, chromosome 17 at 15,053,233 bp (GRCm38)
  • A to G, chromosome 17 at 32,700,211 bp (GRCm38)
  • A to G, chromosome 17 at 49,433,275 bp (GRCm38)
  • G to A, chromosome 17 at 56,661,252 bp (GRCm38)
  • T to C, chromosome 17 at 58,293,917 bp (GRCm38)
  • C to T, chromosome 18 at 67,289,403 bp (GRCm38)
  • A to G, chromosome 18 at 77,873,455 bp (GRCm38)
  • A to G, chromosome 19 at 10,251,161 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9179 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069029-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.