Strain Name:
C57BL/6J-MtgxR9193Btlr/Mmmh
Stock Number:
069038-MU
Citation ID:
RRID:MMRRC_069038-MU
Other Names:
R9193 (G1)
Major Collection:

Strain Information

Sptbn1
Name: spectrin beta, non-erythrocytic 1
Synonyms: beta fodrin, Spnb-2, spectrin G, brain spectrin, elf3, elf1, non-erythrocytic, 9930031C03Rik, Spnb2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20742
Homologene: 2354
P4htm
Name: prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
Synonyms: 4933406E20Rik, P4h-tm
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74443
Homologene: 41765
Tcf7l1
Name: transcription factor 7 like 1 (T cell specific, HMG box)
Synonyms: Tcf3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21415
Homologene: 7563
Tacc2
Name: transforming, acidic coiled-coil containing protein 2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57752
Homologene: 5087
Eif3k
Name: eukaryotic translation initiation factor 3, subunit K
Synonyms: eIF3K, 1200009C21Rik, Eif3s12
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73830
Homologene: 8292
Il2ra
Name: interleukin 2 receptor, alpha chain
Synonyms: IL-2R alpha chain, CD25, Ly-43, Il2r
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16184
HGNC: HGNC:6008
Homologene: 360
Lrrtm3
Name: leucine rich repeat transmembrane neuronal 3
Synonyms: 9630044H04Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216028
Homologene: 37110
Dag1
Name: dystroglycan 1
Synonyms: dystrophin associated glycoprotein 1, DG, D9Wsu13e, alpha-dystroglycan, beta-dystroglycan
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13138
HGNC: HGNC:2666
Homologene: 3234
Nid2
Name: nidogen 2
Synonyms: entactin-2, entactin 2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 18074
VEGA: 14
Homologene: 40575
Edem3
Name: ER degradation enhancer, mannosidase alpha-like 3
Synonyms: 2310050N11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66967
Homologene: 11866
Pgam5
Name: phosphoglycerate mutase family member 5
Synonyms: 2610528A17Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72542
Homologene: 14597
Cachd1
Name: cache domain containing 1
Synonyms: 1190007F10Rik, Vwcd1, B430218L07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320508
Homologene: 10854
Jag1
Name: jagged 1
Synonyms: Serrate-1, Headturner, Htu, ABE2, Ozz, Gsfabe2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16449
HGNC: HGNC:6188
Homologene: 180
Amy1
Name: amylase 1, salivary
Synonyms: Amy-1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11722
Homologene: 20179
Ckap4
Name: cytoskeleton-associated protein 4
Synonyms: CLIMP-63, P63, 5630400A09Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216197
VEGA: 10
Homologene: 4970
Psca
Name: prostate stem cell antigen
Synonyms: 2210408B04Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72373
HGNC: HGNC:9500
Homologene: 4150
Klb
Name: klotho beta
Synonyms: betaKlotho
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 83379
Homologene: 12820
Kidins220
Name: kinase D-interacting substrate 220
Synonyms: 3110039L19Rik, C330002I19Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 77480
VEGA: 12
Homologene: 14254
Nyap2
Name: neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
Synonyms: Jr6, 9430031J16Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241134
Homologene: 18239
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC234973, LOC382129, 9430076A06Rik, D430038H04Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Nalcn
Name: sodium leak channel, non-selective
Synonyms: A530023G15Rik, Vgcnl1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 338370
VEGA: 14
Homologene: 21832
Lrrc7
Name: leucine rich repeat containing 7
Synonyms: densin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242274
Homologene: 10817
Spata31g1
Name: SPATA31 subfamily G member 1
Synonyms: 1700022I11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67317
Homologene: 52406
Farp1
Name: FERM, ARH/RhoGEF and pleckstrin domain protein 1
Synonyms: Cdep
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 223254
HGNC: HGNC:3591
Homologene: 38098
Col14a1
Name: collagen, type XIV, alpha 1
Synonyms: 5730412L22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12818
HGNC: HGNC:2191
Homologene: 18741
Ugt2b38
Name: UDP glucuronosyltransferase 2 family, polypeptide B38
Synonyms: 9430041C03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100559
Homologene: 137225
Or4a71
Name: olfactory receptor family 4 subfamily A member 71
Synonyms: GA_x6K02T2Q125-50972538-50971621, MOR231-4, Olfr1243
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258971
Homologene: 27317
Myom1
Name: myomesin 1
Synonyms: skelemin, D430047A17Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17929
VEGA: 17
HGNC: HGNC:7613
Homologene: 31196
Slc30a10
Name: solute carrier family 30, member 10
Synonyms: E130106K10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226781
VEGA: 1
Homologene: 100946
Zfp735
Name: zinc finger protein 735
Synonyms: 1700012C15Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76390
Homologene: 88945
Lrit2
Name: leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
Synonyms: A930010E21Rik, Lrrc22
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239038
VEGA: 14
Homologene: 18292
Capn13
Name: calpain 13
Synonyms: LOC381122
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381122
VEGA: 17
Homologene: 27026
Bpifa6
Name: BPI fold containing family A, member 6
Synonyms: Gm5840
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 545477
Homologene: 129594
Chil3
Name: chitinase-like 3
Synonyms: Ym1, Chi3l3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12655
Homologene: 74931
H2-M2
Name: histocompatibility 2, M region locus 2
Synonyms: H-2M2, Thy19.4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14990
Homologene: 133732
Trim30c
Name: tripartite motif-containing 30C
Synonyms: Trim30-2, Gm5598
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 434219
Sox5
Name: SRY (sex determining region Y)-box 5
Synonyms: A730017D01Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20678
Homologene: 21378
P3h2
Name: prolyl 3-hydroxylase 2
Synonyms: Leprel1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 210530
Homologene: 10062
Or2a20
Name: olfactory receptor family 2 subfamily A member 2
Synonyms: GA_x6K02T2P3E9-4341246-4340281, MOR261-10, Olfr434
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258366
Homologene: 133700
Nlrp4c
Name: NLR family, pyrin domain containing 4C
Synonyms: Nalp-alpha, Rnh2, Nalp4c
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 83564
Homologene: 75315
Gm57858
Name: gene model 57858
Synonyms: Ccdc144b
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241943
Homologene: 87263
Pank1
Name: pantothenate kinase 1
Synonyms: 5430426F23Rik, Pank1b, Pank1a, Pank1, 4632412I06Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 75735
VEGA: 19
HGNC: HGNC:8598
Homologene: 56979
Gba2
Name: glucosidase beta 2
Synonyms: bile acid
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230101
Homologene: 10859
H2-Bl
Name: histocompatibility 2, blastocyst
Synonyms: blastocyst MHC
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14963
Homologene: 128352
Or8k16
Name: olfactory receptor family 8 subfamily K member 16
Synonyms: GA_x6K02T2Q125-47170431-47171372, MOR187-3, Olfr1008
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258866
Srl
Name: sarcalumenin
Synonyms: sarcalumenin, sar, 9830004M20Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 106393
Homologene: 45500
Gbp8
Name: guanylate-binding protein 8
Synonyms: 5830443L24Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76074
Rgs20
Name: regulator of G-protein signaling 20
Synonyms: Rgsz1, 2900073E09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 58175
Homologene: 2745
Slc30a3
Name: solute carrier family 30 (zinc transporter), member 3
Synonyms: Znt3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22784
Homologene: 74470
Prb1b
Name: proline-rich protein BstNI subfamily 1B
Synonyms: MP5, Prpmp5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 381832
Wdr74
Name: WD repeat domain 74
Synonyms: 5730436H21Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107071
Homologene: 41226
Or10d5j
Name: olfactory receptor family 10 subfamily D member 5J
Synonyms: GA_x6K02T2PVTD-33657378-33656440, MOR224-10, Olfr976
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258364
VEGA: 9
Homologene: 64863
Vmn1r44
Name: vomeronasal 1 receptor 44
Synonyms: V1rb4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113854
Homologene: 113975
Ak1
Name: adenylate kinase 1
Synonyms: Ak-1, B430205N08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11636
HGNC: HGNC:361
Homologene: 20135
Thap7
Name: THAP domain containing 7
Synonyms: 1810004B07Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 69009
Homologene: 12293
Prl2a1
Name: prolactin family 2, subfamily a, member 1
Synonyms: PLP-M, Prlpm
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 56635
Homologene: 10556
Tas2r119
Name: taste receptor, type 2, member 119
Synonyms: mt2r19, Tas2r19, mGR19, T2R19
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 57254
Homologene: 10480
Tnfsf10
Name: tumor necrosis factor (ligand) superfamily, member 10
Synonyms: APO-2L, Trail, A330042I21Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22035
Homologene: 2824
Bcl2l10
Name: Bcl2-like 10
Synonyms: Boo, Diva
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12049
VEGA: 9
HGNC: HGNC:993
Homologene: 8396
S100z
Name: S100 calcium binding protein, zeta
Synonyms: LOC268686
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 268686
VEGA: 13
Homologene: 15633
Trav7-5
Name: T cell receptor alpha variable 7-5
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 630061
Naaladl2
Name: N-acetylated alpha-linked acidic dipeptidase-like 2
Synonyms: LOC381500, 2810043G22Rik, EG635702
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 635702
Homologene: 45786
Ighv7-1
Name: immunoglobulin heavy variable 7-1
Synonyms: Gm16698
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 780799
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 5,020,844 bp (GRCm38)
  • T to C, chromosome 1 at 81,297,997 bp (GRCm38)
  • G to A, chromosome 1 at 151,818,519 bp (GRCm38)
  • T to C, chromosome 1 at 185,462,837 bp (GRCm38)
  • T to C, chromosome 2 at 11,684,391 bp (GRCm38)
  • A to T, chromosome 2 at 32,630,379 bp (GRCm38)
  • C to A, chromosome 2 at 85,690,300 bp (GRCm38)
  • A to G, chromosome 2 at 89,527,643 bp (GRCm38)
  • A to T, chromosome 2 at 137,089,844 bp (GRCm38)
  • G to A, chromosome 2 at 153,984,820 bp (GRCm38)
  • T to C, chromosome 3 at 23,846,578 bp (GRCm38)
  • A to G, chromosome 3 at 27,317,258 bp (GRCm38)
  • G to T, chromosome 3 at 36,035,279 bp (GRCm38)
  • A to G, chromosome 3 at 106,155,765 bp (GRCm38)
  • T to C, chromosome 3 at 113,562,629 bp (GRCm38)
  • A to T, chromosome 3 at 158,353,374 bp (GRCm38)
  • A to G, chromosome 4 at 42,971,519 bp (GRCm38)
  • A to G, chromosome 4 at 43,578,112 bp (GRCm38)
  • C to A, chromosome 4 at 100,777,142 bp (GRCm38)
  • T to C, chromosome 5 at 31,088,744 bp (GRCm38)
  • A to G, chromosome 5 at 65,372,025 bp (GRCm38)
  • A to T, chromosome 5 at 87,423,870 bp (GRCm38)
  • T to C, chromosome 5 at 105,031,303 bp (GRCm38)
  • A to G, chromosome 5 at 110,265,600 bp (GRCm38)
  • A to T, chromosome 6 at 43,217,152 bp (GRCm38)
  • A to G, chromosome 6 at 72,634,222 bp (GRCm38)
  • T to A, chromosome 6 at 89,893,583 bp (GRCm38)
  • T to C, chromosome 6 at 132,312,033 bp (GRCm38)
  • C to T, chromosome 6 at 143,844,844 bp (GRCm38)
  • T to C, chromosome 7 at 6,092,622 bp (GRCm38)
  • T to C, chromosome 7 at 28,974,199 bp (GRCm38)
  • C to T, chromosome 7 at 104,382,346 bp (GRCm38)
  • T to C, chromosome 7 at 130,626,574 bp (GRCm38)
  • A to G, chromosome 9 at 15,998,952 bp (GRCm38)
  • T to C, chromosome 9 at 39,956,582 bp (GRCm38)
  • A to G, chromosome 9 at 75,348,051 bp (GRCm38)
  • A to G, chromosome 9 at 108,208,268 bp (GRCm38)
  • A to G, chromosome 9 at 108,582,882 bp (GRCm38)
  • A to G, chromosome 10 at 39,075,448 bp (GRCm38)
  • A to T, chromosome 10 at 63,930,104 bp (GRCm38)
  • A to G, chromosome 10 at 84,527,486 bp (GRCm38)
  • C to T, chromosome 11 at 30,137,551 bp (GRCm38)
  • A to T, chromosome 11 at 73,689,774 bp (GRCm38)
  • A to T, chromosome 12 at 24,986,967 bp (GRCm38)
  • T to A, chromosome 12 at 113,896,490 bp (GRCm38)
  • T to A, chromosome 13 at 27,808,552 bp (GRCm38)
  • C to T, chromosome 13 at 95,477,375 bp (GRCm38)
  • T to C, chromosome 14 at 19,803,210 bp (GRCm38)
  • A to G, chromosome 14 at 37,072,593 bp (GRCm38)
  • C to G, chromosome 14 at 53,531,158 bp (GRCm38)
  • T to C, chromosome 14 at 121,280,869 bp (GRCm38)
  • A to T, chromosome 14 at 123,308,380 bp (GRCm38)
  • T to G, chromosome 15 at 32,177,786 bp (GRCm38)
  • A to G, chromosome 15 at 55,379,568 bp (GRCm38)
  • C to T, chromosome 15 at 74,716,083 bp (GRCm38)
  • T to C, chromosome 16 at 4,493,859 bp (GRCm38)
  • A to T, chromosome 16 at 17,529,037 bp (GRCm38)
  • T to C, chromosome 16 at 26,105,241 bp (GRCm38)
  • A to G, chromosome 17 at 36,081,064 bp (GRCm38)
  • T to A, chromosome 17 at 37,482,537 bp (GRCm38)
  • A to G, chromosome 17 at 71,036,300 bp (GRCm38)
  • A to T, chromosome 17 at 73,345,196 bp (GRCm38)
  • T to A, chromosome 19 at 8,737,876 bp (GRCm38)
  • T to A, chromosome 19 at 34,827,234 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9193 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069038-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.