Strain Name:
C57BL/6J-MtgxR9201Btlr/Mmmh
Stock Number:
069041-MU
Citation ID:
RRID:MMRRC_069041-MU
Other Names:
R9201 (G1)
Major Collection:

Strain Information

Ptprz1
Name: protein tyrosine phosphatase receptor type Z, polypeptide 1
Synonyms: PTPzeta, DSD-1-PG, phosphacan, RPTPz, Ptprz, Ptpz, Rptpbeta, PTPbeta
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Spidr
Name: scaffolding protein involved in DNA repair
Synonyms: 2310008H04Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224008
VEGA: 16
Homologene: 51693
Smc2
Name: structural maintenance of chromosomes 2
Synonyms: CAP-E, Smc2l1, 5730502P04Rik, Fin16
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14211
Homologene: 4705
Ankrd17
Name: ankyrin repeat domain 17
Synonyms: Gtar, 4933425K22Rik, A130069E23Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 81702
Homologene: 82403
Nf1
Name: neurofibromin 1
Synonyms: Mhdadsk9, neurofibromin, Nf-1, Dsk9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Usp24
Name: ubiquitin specific peptidase 24
Synonyms: 2810030C21Rik, 2700066K03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329908
Homologene: 35420
Atxn10
Name: ataxin 10
Synonyms: Sca10, Tex169, E46, TEG-169
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 54138
VEGA: 15
Homologene: 40858
Txnrd1
Name: thioredoxin reductase 1
Synonyms: TrxR1, TR, TR alpha, TR1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 50493
VEGA: 10
Homologene: 55733
Fgfr1op2
Name: FGFR1 oncogene partner 2
Synonyms: 1500031J01Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67529
Homologene: 9222
Zfp369
Name: zinc finger protein 369
Synonyms: B930030B22Rik, NRIF2, D230020H11Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 170936
Homologene: 129707
Nrip3
Name: nuclear receptor interacting protein 3
Synonyms: A330103B05Rik, ICRFP703N2430Q5.2, D7H11orf14, ICRFP703B1614Q5.2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 78593
HGNC: HGNC:1167
Homologene: 10764
Ero1a
Name: endoplasmic reticulum oxidoreductase 1 alpha
Synonyms: Ero1l
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50527
VEGA: 14
Homologene: 49392
Dcbld1
Name: discoidin, CUB and LCCL domain containing 1
Synonyms: 4631413K11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66686
Homologene: 12010
Edem3
Name: ER degradation enhancer, mannosidase alpha-like 3
Synonyms: 2310050N11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66967
Homologene: 11866
Kmt5a
Name: lysine methyltransferase 5A
Synonyms: PR-SET7, Setd8, 2410195B05Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67956
Homologene: 41372
Tsc1
Name: TSC complex subunit 1
Synonyms: tuberous sclerosis 1, hamartin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 64930
Homologene: 314
Cat
Name: catalase
Synonyms: Cas1, Cs-1, Cas-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12359
HGNC: HGNC:1516
Homologene: 55514
Spata31d1c
Name: spermatogenesis associated 31 subfamily D, member 1C
Synonyms: Fam75d1c, 4932441B19Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238683
VEGA: 13
Celsr1
Name: cadherin, EGF LAG seven-pass G-type receptor 1
Synonyms: crash, Adgrc1, Crsh, Scy
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12614
VEGA: 15
HGNC: HGNC:1850
Homologene: 7665
Rbm15b
Name: RNA binding motif protein 15B
Synonyms: 1810017N16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 109095
Homologene: 8325
Siglecl2
Name: Siglec family like 2
Synonyms: 4931406B18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74054
Homologene: 105741
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329628
Homologene: 14377
Ppfia2
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
Synonyms: E130120L08Rik, Liprin-alpha2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 327814
VEGA: 10
HGNC: HGNC:9246
Homologene: 27953
Tdrd6
Name: tudor domain containing 6
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 210510
Homologene: 19364
Clca3a2
Name: chloride channel accessory 3A2
Synonyms: Clca2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80797
HGNC: HGNC:2017
Homologene: 77224
Slc4a5
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 5
Synonyms: C330016K18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232156
Homologene: 31125
Cdh12
Name: cadherin 12
Synonyms: Br-cadherin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 215654
HGNC: HGNC:1751
Homologene: 37873
Bpifb2
Name: BPI fold containing family B, member 2
Synonyms: Bpil1, 2310069A01Rik, 2310034L21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66557
Homologene: 11884
Or14c40
Name: olfactory receptor family 14 subfamily C member 40
Synonyms: MOR221-3, GA_x6K02T2NHDJ-9457744-9456734, Olfr293
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257906
Homologene: 79385
Ppp2r1b
Name: protein phosphatase 2, regulatory subunit A, beta
Synonyms: 2410091N08Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73699
HGNC: HGNC:9303
Homologene: 70244
Afap1l2
Name: actin filament associated protein 1-like 2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226250
Homologene: 13057
Nrap
Name: nebulin-related anchoring protein
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18175
HGNC: HGNC:7988
Homologene: 4499
Il18rap
Name: interleukin 18 receptor accessory protein
Synonyms: AcPL accessory protein-like)
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16174
HGNC: HGNC:5989
Homologene: 2859
Cimap3
Name: ciliary microtubule associated protein 3
Synonyms: 1700027A23Rik, Pifo, pitchfork
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 100503311
Homologene: 18759
Abcc2
Name: ATP-binding cassette, sub-family member 2
Synonyms: multidrug resistance protein 2, Mrp2, Cmoat
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12780
HGNC: HGNC:53
Homologene: 68052
Or9a7
Name: olfactory receptor family 9 subfamily A member 7
Synonyms: Olfr461, MOR120-3, GA_x6K02T2P3E9-6973252-6974193
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258380
HGNC: HGNC:8486
Homologene: 64891
Fhod3
Name: formin homology 2 domain containing 3
Synonyms: A930009H06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225288
VEGA: 18
Homologene: 45323
Nudcd1
Name: NudC domain containing 1
Synonyms: 4921532K09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67429
VEGA: 15
Homologene: 12128
Lax1
Name: lymphocyte transmembrane adaptor 1
Synonyms: E430019B13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240754
Homologene: 49504
Clip4
Name: CAP-GLY domain containing linker protein family, member 4
Synonyms: 1700024K14Rik, 1700074B05Rik, 4833417L20Rik, 5830409B12Rik, Rsnl2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78785
VEGA: 17
Homologene: 11662
Ppp2r2b
Name: protein phosphatase 2, regulatory subunit B, beta
Synonyms: PR55-BETA, E130009M08Rik, 6330404L05Rik, 2900026H06Rik, SCA12, PP2A-PR55B
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 72930
HGNC: HGNC:9305
Homologene: 55833
Snai2
Name: snail family zinc finger 2
Synonyms: Slug, Snail2, Slugh
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 20583
VEGA: 16
Homologene: 31127
Stox1
Name: storkhead box 1
Synonyms: 4732470K04Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216021
Homologene: 17649
Paqr3
Name: progestin and adipoQ receptor family member III
Synonyms: RKTG, 6330415A20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231474
Homologene: 71077
Dcaf15
Name: DDB1 and CUL4 associated factor 15
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212123
Homologene: 18182
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to T, chromosome 1 at 40,543,017 bp (GRCm38)
  • A to T, chromosome 1 at 133,680,467 bp (GRCm38)
  • G to T, chromosome 1 at 151,818,573 bp (GRCm38)
  • T to C, chromosome 2 at 28,686,779 bp (GRCm38)
  • A to T, chromosome 2 at 103,474,409 bp (GRCm38)
  • A to T, chromosome 2 at 153,891,983 bp (GRCm38)
  • T to C, chromosome 3 at 38,890,930 bp (GRCm38)
  • T to A, chromosome 3 at 105,999,605 bp (GRCm38)
  • A to G, chromosome 3 at 144,813,923 bp (GRCm38)
  • T to A, chromosome 4 at 52,446,044 bp (GRCm38)
  • T to A, chromosome 4 at 106,420,530 bp (GRCm38)
  • A to T, chromosome 5 at 90,230,939 bp (GRCm38)
  • A to T, chromosome 5 at 93,638,078 bp (GRCm38)
  • A to G, chromosome 5 at 97,097,506 bp (GRCm38)
  • A to T, chromosome 5 at 124,459,849 bp (GRCm38)
  • G to T, chromosome 6 at 22,972,870 bp (GRCm38)
  • C to T, chromosome 6 at 40,544,359 bp (GRCm38)
  • C to T, chromosome 6 at 83,285,830 bp (GRCm38)
  • A to G, chromosome 6 at 146,592,719 bp (GRCm38)
  • A to G, chromosome 7 at 43,501,285 bp (GRCm38)
  • T to C, chromosome 7 at 86,664,541 bp (GRCm38)
  • T to C, chromosome 7 at 109,761,699 bp (GRCm38)
  • T to C, chromosome 8 at 84,102,070 bp (GRCm38)
  • T to A, chromosome 9 at 50,878,147 bp (GRCm38)
  • A to G, chromosome 9 at 106,885,019 bp (GRCm38)
  • A to G, chromosome 10 at 52,261,904 bp (GRCm38)
  • A to G, chromosome 10 at 62,665,573 bp (GRCm38)
  • T to C, chromosome 10 at 82,883,987 bp (GRCm38)
  • T to C, chromosome 10 at 106,842,779 bp (GRCm38)
  • T to C, chromosome 11 at 79,570,330 bp (GRCm38)
  • A to G, chromosome 13 at 65,036,959 bp (GRCm38)
  • T to C, chromosome 13 at 65,296,582 bp (GRCm38)
  • A to G, chromosome 14 at 45,287,757 bp (GRCm38)
  • T to C, chromosome 15 at 21,237,739 bp (GRCm38)
  • T to C, chromosome 15 at 44,400,077 bp (GRCm38)
  • T to C, chromosome 15 at 85,359,486 bp (GRCm38)
  • G to T, chromosome 15 at 86,033,085 bp (GRCm38)
  • A to T, chromosome 16 at 14,706,768 bp (GRCm38)
  • G to T, chromosome 16 at 15,912,692 bp (GRCm38)
  • T to C, chromosome 17 at 43,625,670 bp (GRCm38)
  • G to A, chromosome 17 at 71,810,889 bp (GRCm38)
  • T to A, chromosome 18 at 24,994,556 bp (GRCm38)
  • A to G, chromosome 18 at 42,738,036 bp (GRCm38)
  • T to C, chromosome 19 at 43,798,441 bp (GRCm38)
  • T to A, chromosome 19 at 56,351,661 bp (GRCm38)
  • C to A, chromosome 19 at 56,928,256 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9201 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069041-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.