Strain Name:
C57BL/6J-MtgxR9252Btlr/Mmmh
Stock Number:
069075-MU
Citation ID:
RRID:MMRRC_069075-MU
Other Names:
R9252 (G1)
Major Collection:

Strain Information

Cd74
Name: CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
Synonyms: CLIP, Ii
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 16149
VEGA: 18
HGNC: HGNC:1697
Homologene: 3209
Pik3cd
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Synonyms: p110delta, 2410099E07Rik, 2610208K16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18707
HGNC: HGNC:8977
Homologene: 3686
Plcd3
Name: phospholipase C, delta 3
Synonyms: 2610205J15Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72469
HGNC: HGNC:9061
Homologene: 14858
Acap2
Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
Synonyms: 9530039J15Rik, Centb2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78618
VEGA: 16
Homologene: 8182
Mib1
Name: MIB E3 ubiquitin protein ligase 1
Synonyms: E430019M12Rik, mindbomb, Mib, mind bomb-1, skeletrophin
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225164
Homologene: 10810
Cdca2
Name: cell division cycle associated 2
Synonyms: 2610311M19Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 108912
Homologene: 18444
Nfya
Name: nuclear transcription factor-Y alpha
Synonyms: Sez10, Cbf-b
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18044
HGNC: HGNC:7804
Homologene: 32114
Stat1
Name: signal transducer and activator of transcription 1
Synonyms: 2010005J02Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20846
Homologene: 21428
Arfgef1
Name: ADP ribosylation factor guanine nucleotide exchange factor 1
Synonyms: BIG1, P200, ARFGEP1, D730028O18Rik, D130059B05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 211673
Homologene: 4687
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: 2810449H11Rik, D130015N03Rik, tbl
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Nhsl3
Name: NHS like 3
Synonyms: C77080
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 97130
Homologene: 45837
Atp6v1d
Name: ATPase, H+ transporting, lysosomal V1 subunit D
Synonyms: Atp6m, VATD, 1110004P10Rik, lysosomal 34kDa, Vma8
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 73834
VEGA: 12
Homologene: 5783
Ccp110
Name: centriolar coiled coil protein 110
Synonyms: 6330503K22Rik, CP110
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101565
Homologene: 8810
Nktr
Name: natural killer tumor recognition sequence
Synonyms: 5330401F18Rik, D9Wsu172e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18087
HGNC: HGNC:7833
Homologene: 122148
Twf2
Name: twinfilin actin binding protein 2
Synonyms: Ptk9l, A6-related, Twinfilin-2, Twf2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 23999
HGNC: HGNC:9621
Homologene: 5272
Plekhm2
Name: pleckstrin homology domain containing, family M (with RUN domain) member 2
Synonyms: 2310034J19Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69582
Homologene: 19575
Ube3d
Name: ubiquitin protein ligase E3D
Synonyms: 2610018I03Rik, Ube2cbp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70348
Homologene: 18898
Ddx11
Name: DEAD/H box helicase 11
Synonyms: 4732462I11Rik, CHLR1, essa15a, KRG2, CHL1, DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320209
VEGA: 17
Homologene: 68973
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: Ttc40, 9330101J02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212124
Prlr
Name: prolactin receptor
Synonyms: Pr-1, Prlr-rs1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 19116
HGNC: HGNC:9446
Homologene: 733
Plcd4
Name: phospholipase C, delta 4
Synonyms: 4921507K24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18802
HGNC: HGNC:9062
Homologene: 88782
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Ttpal
Name: tocopherol (alpha) transfer protein-like
Synonyms: 3110080A02Rik, 5830472M02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76080
Homologene: 41562
Ptprq
Name: protein tyrosine phosphatase receptor type Q
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237523
HGNC: HGNC:9679
Homologene: 83557
Stk10
Name: serine/threonine kinase 10
Synonyms: Gek1, Lok
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20868
Homologene: 38122
Adgrb3
Name: adhesion G protein-coupled receptor B3
Synonyms: Bai3, A830096D10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210933
HGNC: HGNC:945
Homologene: 1289
Mgam
Name: maltase-glucoamylase
Synonyms: 6030407P20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232714
HGNC: HGNC:7043
Homologene: 130099
Myh8
Name: myosin, heavy polypeptide 8, skeletal muscle, perinatal
Synonyms: Myhsp, Myhs-p, 4832426G23Rik, MyHC-pn
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17885
HGNC: HGNC:7578
Homologene: 68256
Unc13c
Name: unc-13 homolog C
Synonyms: D9Ertd414e, Munc13-3, 1500037O19Rik, Unc13h3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208898
Homologene: 45443
Kif1a
Name: kinesin family member 1A
Synonyms: ATSV, N-3 kinesin, Kns1, LOC381283, C630002N23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16560
HGNC: HGNC:888
Homologene: 99729
Gucy2d
Name: guanylate cyclase 2d
Synonyms: guanylyl cyclase D
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14918
Homologene: 71540
Jakmip2
Name: janus kinase and microtubule interacting protein 2
Synonyms: 6430702L21Rik, D930046L20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 76217
VEGA: 18
Homologene: 8866
Ccdc146
Name: coiled-coil domain containing 146
Synonyms: 4930528G09Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75172
Homologene: 67159
Sult1e1
Name: sulfotransferase family 1E, member 1
Synonyms: Ste, EST
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20860
Homologene: 101388
Shank2
Name: SH3 and multiple ankyrin repeat domains 2
Synonyms: ProSAP1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210274
Homologene: 105965
Ccdc27
Name: coiled-coil domain containing 27
Synonyms: LOC381580
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381580
Homologene: 17596
Kcnj2
Name: potassium inwardly-rectifying channel, subfamily J, member 2
Synonyms: Kcnf1, IRK1, Kir2.1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16518
HGNC: HGNC:6263
Homologene: 20249
Slc24a1
Name: solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214111
VEGA: 9
Homologene: 3472
Brme1
Name: break repair meiotic recombinase recruitment factor 1
Synonyms: 4930432K21Rik, Mamerr, Meiok21
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74666
Homologene: 11525
Stat6
Name: signal transducer and activator of transcription 6
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20852
Homologene: 2373
Ildr1
Name: immunoglobulin-like domain containing receptor 1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 106347
Homologene: 15892
Ugt1a8
Name: UDP glucuronosyltransferase 1 family, polypeptide A8
Synonyms: OTTMUSG00000020811, A116
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 613123
Thsd4
Name: thrombospondin, type I, domain containing 4
Synonyms: B230114P05Rik, ADAMTSL6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 207596
Homologene: 49796
Scg2
Name: secretogranin II
Synonyms: SgII, Chgc
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20254
Homologene: 2591
Pde8b
Name: phosphodiesterase 8B
Synonyms: B230331L10Rik, C030047E14Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218461
HGNC: HGNC:8794
Homologene: 2758
St8sia4
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
Synonyms: Siat8d, PST, PST-1, ST8SiaIV
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20452
Homologene: 4147
Tsga10
Name: testis specific 10
Synonyms: Mtsga10, 4933432N21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 211484
Homologene: 23531
Nox4
Name: NADPH oxidase 4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 50490
HGNC: HGNC:7891
Homologene: 41065
Slc23a2
Name: solute carrier family 23 (nucleobase transporters), member 2
Synonyms: SVCT2, Slc23a1, YSPL3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 54338
Homologene: 68440
Car15
Name: carbonic anhydrase 15
Synonyms: Cals2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 80733
Homologene: 113791
Vmn2r97
Name: vomeronasal 2, receptor 97
Synonyms: EG627367
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627367
Homologene: 115024
Tbc1d12
Name: TBC1D12: TBC1 domain family, member 12
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 209478
VEGA: 19
Homologene: 50835
Mzf1
Name: myeloid zinc finger 1
Synonyms: Zfp121, Znf42, Mzf2, Zfp98
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 109889
Homologene: 9633
Pnlip
Name: pancreatic lipase
Synonyms: 1810007A24Rik, PTL, pancreatic triglyceride lipase
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 69060
VEGA: 19
HGNC: HGNC:9155
Homologene: 30999
Or13c7b
Name: olfactory receptor family 13 subfamily C member 7B
Synonyms: Olfr156, mOR37b, Olfr37b, MOR262-6, GA_x6K02T2N78B-16125144-16126100, OR37B
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 29846
Homologene: 133652
Cimap1b
Name: ciliary microtubule associated protein 1B
Synonyms: Odf3b, 2010001J22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 70113
VEGA: 15
Homologene: 28256
Rtkn
Name: rhotekin
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20166
Homologene: 7522
Catspere2
Name: cation channel sperm associated auxiliary subunit epsilon 2
Synonyms: EG545391, Gm30473, Gm16432
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545391
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 10,172,897 bp (GRCm38)
  • T to C, chromosome 1 at 25,826,415 bp (GRCm38)
  • T to A, chromosome 1 at 37,834,283 bp (GRCm38)
  • C to A, chromosome 1 at 52,135,672 bp (GRCm38)
  • A to G, chromosome 1 at 74,549,200 bp (GRCm38)
  • C to T, chromosome 1 at 79,436,352 bp (GRCm38)
  • T to C, chromosome 1 at 88,087,984 bp (GRCm38)
  • T to A, chromosome 1 at 93,075,054 bp (GRCm38)
  • CCTCT to CCT, chromosome 1 at 95,627,507 bp (GRCm38)
  • A to T, chromosome 1 at 178,111,430 bp (GRCm38)
  • A to T, chromosome 2 at 76,770,512 bp (GRCm38)
  • A to T, chromosome 2 at 132,071,922 bp (GRCm38)
  • T to G, chromosome 2 at 163,607,185 bp (GRCm38)
  • C to T, chromosome 4 at 43,821,109 bp (GRCm38)
  • A to G, chromosome 4 at 129,223,476 bp (GRCm38)
  • T to C, chromosome 4 at 141,629,132 bp (GRCm38)
  • A to G, chromosome 4 at 149,655,630 bp (GRCm38)
  • A to T, chromosome 4 at 154,041,050 bp (GRCm38)
  • T to C, chromosome 5 at 21,297,025 bp (GRCm38)
  • G to T, chromosome 5 at 87,590,114 bp (GRCm38)
  • T to G, chromosome 6 at 40,729,643 bp (GRCm38)
  • A to G, chromosome 6 at 83,148,162 bp (GRCm38)
  • T to C, chromosome 7 at 13,043,720 bp (GRCm38)
  • G to A, chromosome 7 at 87,376,240 bp (GRCm38)
  • G to A, chromosome 7 at 98,467,772 bp (GRCm38)
  • A to G, chromosome 7 at 118,722,450 bp (GRCm38)
  • A to T, chromosome 7 at 139,618,249 bp (GRCm38)
  • A to G, chromosome 7 at 144,068,798 bp (GRCm38)
  • A to G, chromosome 8 at 84,172,249 bp (GRCm38)
  • C to A, chromosome 9 at 60,056,947 bp (GRCm38)
  • T to A, chromosome 9 at 64,928,112 bp (GRCm38)
  • T to A, chromosome 9 at 66,402,552 bp (GRCm38)
  • A to T, chromosome 9 at 73,517,271 bp (GRCm38)
  • C to A, chromosome 9 at 86,372,448 bp (GRCm38)
  • A to G, chromosome 9 at 106,211,800 bp (GRCm38)
  • T to C, chromosome 9 at 121,750,349 bp (GRCm38)
  • A to G, chromosome 10 at 107,686,386 bp (GRCm38)
  • A to C, chromosome 10 at 127,647,792 bp (GRCm38)
  • G to T, chromosome 11 at 32,588,915 bp (GRCm38)
  • G to T, chromosome 11 at 67,286,476 bp (GRCm38)
  • G to T, chromosome 11 at 103,077,554 bp (GRCm38)
  • A to G, chromosome 11 at 111,072,529 bp (GRCm38)
  • T to A, chromosome 12 at 78,857,249 bp (GRCm38)
  • C to T, chromosome 13 at 95,032,916 bp (GRCm38)
  • T to A, chromosome 14 at 67,677,382 bp (GRCm38)
  • A to G, chromosome 15 at 10,326,464 bp (GRCm38)
  • T to C, chromosome 15 at 89,378,398 bp (GRCm38)
  • A to T, chromosome 16 at 17,835,382 bp (GRCm38)
  • A to G, chromosome 16 at 31,101,823 bp (GRCm38)
  • G to A, chromosome 16 at 36,716,212 bp (GRCm38)
  • A to T, chromosome 17 at 18,947,587 bp (GRCm38)
  • T to C, chromosome 17 at 48,392,915 bp (GRCm38)
  • G to A, chromosome 17 at 66,150,812 bp (GRCm38)
  • T to G, chromosome 18 at 10,800,088 bp (GRCm38)
  • T to A, chromosome 18 at 43,582,129 bp (GRCm38)
  • T to A, chromosome 18 at 60,808,292 bp (GRCm38)
  • A to G, chromosome 19 at 38,911,033 bp (GRCm38)
  • T to A, chromosome 19 at 58,680,841 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9252 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069075-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.