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Strain Name:
C57BL/6J-MtgxR9277Btlr/Mmmh
Stock Number:
069096-MU
Citation ID:
RRID:MMRRC_069096-MU
Other Names:
R9277 (G1)
Major Collection:

Strain Information

Magi1
Name: membrane associated guanylate kinase, WW and PDZ domain containing 1
Synonyms: WWP3, Gukmi1, AIP3, BAP1, Baiap1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14924
HGNC: HGNC:946
Homologene: 31257
Cdyl
Name: chromodomain protein, Y chromosome-like
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 12593
VEGA: 13
HGNC: HGNC:1811
Homologene: 3548
Prtg
Name: protogenin
Synonyms: A230098A12Rik, Igdcc5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235472
Homologene: 54453
Eif4g2
Name: eukaryotic translation initiation factor 4, gamma 2
Synonyms: Nat1, DAP-5, Natm1, E130105L11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13690
HGNC: HGNC:3297
Homologene: 37477
Setd2
Name: SET domain containing 2
Synonyms: 4921524K10Rik, KMT3A
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235626
Homologene: 56493
Pkn2
Name: protein kinase N2
Synonyms: PRK2, 6030436C20Rik, Stk7, Prkcl2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109333
HGNC: HGNC:9406
Homologene: 2054
Xpo1
Name: exportin 1
Synonyms: Crm1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103573
Homologene: 2554
Fancl
Name: Fanconi anemia, complementation group L
Synonyms: 2010322C19Rik, gcd, Pog, Phf9, B230118H11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67030
Homologene: 9987
Afdn
Name: afadin, adherens junction formation factor
Synonyms: AF6, Afadin, S-afadin, I-afadin, 5033403D15Rik, Mllt4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17356
HGNC: HGNC:7137
Homologene: 21202
Eftud2
Name: elongation factor Tu GTP binding domain containing 2
Synonyms: U5-116kD, 116kDa, Snrp116
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20624
Homologene: 3133
Parn
Name: poly(A)-specific ribonuclease (deadenylation nuclease)
Synonyms: DAN, 1200003I18Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74108
VEGA: 16
HGNC: HGNC:8609
Homologene: 31098
Dhx40
Name: DEAH-box helicase 40
Synonyms: ARG147, DDX40, 2410016C14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67487
Homologene: 57000
Golga1
Name: golgin A1
Synonyms: golgin-97, 0710001G09Rik, 2210418B03Rik, Golgi97, awag
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76899
HGNC: HGNC:4424
Homologene: 68223
Pip4k2b
Name: phosphatidylinositol-5-phosphate 4-kinase, type II, beta
Synonyms: c11, PI5P4Kbeta, Pip5k2b
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 108083
HGNC: HGNC:8998
Homologene: 2634
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Adam12
Name: ADAM metallopeptidase domain 12
Synonyms: Mltna, ADAM12
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11489
HGNC: HGNC:190
Homologene: 74862
Dars2
Name: aspartyl-tRNA synthetase 2 (mitochondrial)
Synonyms: 5830468K18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226539
Homologene: 7093
Dnajc14
Name: DnaJ heat shock protein family (Hsp40) member C14
Synonyms: DRIP78, LIP6, HDJ3, 5730551F12Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74330
VEGA: 10
Homologene: 12553
Lgr6
Name: leucine-rich repeat-containing G protein-coupled receptor 6
Synonyms: A530037C04Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329252
Homologene: 49680
Slc49a3
Name: solute carrier family 49 member 3
Synonyms: 4732482E20Rik, Mfsd7, Mfsd7a
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243197
VEGA: 5
Homologene: 49990
Lamtor5
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Synonyms: 1110003H18Rik, Hbxip
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 68576
Homologene: 4668
Fhip1a
Name: FHF complex subunit HOOK interacting protein 1A
Synonyms: 9930021J17Rik, Fam160a1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229488
Homologene: 85149
Maml2
Name: mastermind like transcriptional coactivator 2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270118
Homologene: 134147
Vwa3b
Name: von Willebrand factor A domain containing 3B
Synonyms: A230074B11Rik, 4921511C04Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70853
Homologene: 27053
Fermt3
Name: fermitin family member 3
Synonyms: C79673, Kindlin-3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 108101
VEGA: 19
Homologene: 12877
Nalcn
Name: sodium leak channel, non-selective
Synonyms: A530023G15Rik, Vgcnl1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 338370
VEGA: 14
Homologene: 21832
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22635
Homologene: 124417
Morc2b
Name: microrchidia 2B
Synonyms: 4932411A10Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240069
Homologene: 18615
Npsr1
Name: neuropeptide S receptor 1
Synonyms: PGR14, VRR1, 9330128H10Rik, Gpr154
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 319239
Homologene: 45515
Abca8b
Name: ATP-binding cassette, sub-family A member 8b
Synonyms: Abca8
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 27404
HGNC: HGNC:38
Homologene: 56029
Tmem145
Name: transmembrane protein 145
Synonyms: B930076A02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330485
Homologene: 18333
Frem3
Name: Fras1 related extracellular matrix protein 3
Synonyms: LOC333315
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 333315
Homologene: 35388
Vmn2r66
Name: vomeronasal 2, receptor 66
Synonyms: F830104D24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233437
Homologene: 115466
Igfn1
Name: immunoglobulin-like and fibronectin type III domain containing 1
Synonyms: 9830123M21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226438
Homologene: 130054
Scgb1b20
Name: secretoglobin, family 1B, member 20
Synonyms: Gm7147, Gm5895, Abpa20
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 545948
Homologene: 114479
Itga2b
Name: integrin alpha 2b
Synonyms: platelet glycoprotein IIb, GpIIb, alphaIIb, CD41, GP IIb
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16399
HGNC: HGNC:6138
Homologene: 37304
Obox5
Name: oocyte specific homeobox 5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 252829
Homologene: 44937
Vmn1r19
Name: vomeronasal 1 receptor 19
Synonyms: V1rc27
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171200
Homologene: 134034
Clip2
Name: CAP-GLY domain containing linker protein 2
Synonyms: CLIP-115, WSCR4, Cyln2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269713
HGNC: HGNC:2586
Homologene: 20718
Zer1
Name: zyg-11 related, cell cycle regulator
Synonyms: C230075L19Rik, Zyg11bl
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227693
Homologene: 4621
Zfp827
Name: zinc finger protein 827
Synonyms: 2810449M09Rik, D630040G17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 622675
Homologene: 45622
Zswim9
Name: zinc finger SWIM-type containing 9
Synonyms: 6330408A02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 321008
Homologene: 52386
Rgs7bp
Name: regulator of G-protein signalling 7 binding protein
Synonyms: A930030I01Rik, R7bp, D13Bwg1146e
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 52882
VEGA: 13
Homologene: 78705
Hoxd9
Name: homeobox D9
Synonyms: Hox-5.2, Hox-4.4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15438
HGNC: HGNC:5140
Homologene: 8409
Faim2
Name: Fas apoptotic inhibitory molecule 2
Synonyms: NMP25, 2900002L20Rik, lifeguard, Lfg, Tmbim2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72393
VEGA: 15
Homologene: 8192
Coq8a
Name: coenzyme Q8A
Synonyms: 4632432J16Rik, Cabc1, Adck3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67426
Homologene: 11345
Klrg2
Name: killer cell lectin-like receptor subfamily G, member 2
Synonyms: 2310020F24Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74253
Homologene: 52362
Zdhhc19
Name: zinc finger, DHHC domain containing 19
Synonyms: LOC245308
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 245308
Homologene: 34922
Vmn1r169
Name: vomeronasal 1 receptor 169
Synonyms: Gm4232
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100043103
Homologene: 128341
Gm10330
Name: predicted gene 10330
Type: Gene
Species: Mouse
Chromosome: 12
Gpatch11
Name: G patch domain containing 11
Synonyms: 2310002B06Rik, Ccdc75
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 53951
VEGA: 17
Homologene: 44687
Cela1
Name: chymotrypsin-like elastase family, member 1
Synonyms: PC-TsF, Ela-1, 1810009A17Rik, 1810062B19Rik, Ela1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 109901
VEGA: 15
HGNC: HGNC:3308
Homologene: 20454
Trmt5
Name: TRM5 tRNA methyltransferase 5
Synonyms: 2610027O18Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76357
VEGA: 12
Homologene: 6096
Plpp7
Name: phospholipid phosphatase 7 (inactive)
Synonyms: D830019K17Rik, NET39, Ppapdc3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227721
Homologene: 41885
Wbp4
Name: WW domain binding protein 4
Synonyms: FBP21
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 22380
VEGA: 14
Homologene: 38287
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 37,157,453 bp (GRCm38)
  • G to T, chromosome 1 at 134,987,479 bp (GRCm38)
  • C to T, chromosome 1 at 135,959,782 bp (GRCm38)
  • G to A, chromosome 1 at 161,049,957 bp (GRCm38)
  • G to A, chromosome 1 at 180,179,211 bp (GRCm38)
  • G to A, chromosome 2 at 30,111,285 bp (GRCm38)
  • A to T, chromosome 2 at 32,095,812 bp (GRCm38)
  • T to C, chromosome 2 at 39,024,243 bp (GRCm38)
  • A to G, chromosome 2 at 74,699,195 bp (GRCm38)
  • A to G, chromosome 2 at 91,175,710 bp (GRCm38)
  • C to A, chromosome 3 at 85,672,258 bp (GRCm38)
  • A to G, chromosome 3 at 107,279,088 bp (GRCm38)
  • A to G, chromosome 3 at 142,810,748 bp (GRCm38)
  • T to C, chromosome 5 at 94,614,984 bp (GRCm38)
  • A to G, chromosome 5 at 94,624,058 bp (GRCm38)
  • G to T, chromosome 5 at 108,441,998 bp (GRCm38)
  • A to G, chromosome 5 at 134,500,109 bp (GRCm38)
  • G to A, chromosome 5 at 137,463,992 bp (GRCm38)
  • A to G, chromosome 6 at 38,636,556 bp (GRCm38)
  • A to T, chromosome 6 at 57,405,337 bp (GRCm38)
  • A to T, chromosome 6 at 93,943,253 bp (GRCm38)
  • A to G, chromosome 7 at 13,261,057 bp (GRCm38)
  • A to T, chromosome 7 at 15,757,952 bp (GRCm38)
  • A to T, chromosome 7 at 23,577,965 bp (GRCm38)
  • A to G, chromosome 7 at 25,309,740 bp (GRCm38)
  • G to A, chromosome 7 at 33,373,573 bp (GRCm38)
  • T to C, chromosome 7 at 85,011,956 bp (GRCm38)
  • G to A, chromosome 7 at 111,074,859 bp (GRCm38)
  • T to C, chromosome 7 at 133,919,832 bp (GRCm38)
  • C to T, chromosome 8 at 79,060,400 bp (GRCm38)
  • T to A, chromosome 8 at 80,690,773 bp (GRCm38)
  • A to G, chromosome 9 at 13,620,576 bp (GRCm38)
  • A to G, chromosome 9 at 24,313,197 bp (GRCm38)
  • G to A, chromosome 9 at 72,809,647 bp (GRCm38)
  • A to G, chromosome 9 at 110,550,551 bp (GRCm38)
  • A to G, chromosome 10 at 128,806,820 bp (GRCm38)
  • A to G, chromosome 11 at 23,291,550 bp (GRCm38)
  • A to T, chromosome 11 at 26,468,847 bp (GRCm38)
  • C to T, chromosome 11 at 86,770,230 bp (GRCm38)
  • A to T, chromosome 11 at 97,722,446 bp (GRCm38)
  • A to G, chromosome 11 at 102,461,156 bp (GRCm38)
  • A to C, chromosome 11 at 102,860,029 bp (GRCm38)
  • T to C, chromosome 11 at 109,976,521 bp (GRCm38)
  • A to T, chromosome 12 at 8,011,183 bp (GRCm38)
  • A to T, chromosome 12 at 23,779,910 bp (GRCm38)
  • C to A, chromosome 12 at 73,282,674 bp (GRCm38)
  • A to G, chromosome 13 at 35,858,239 bp (GRCm38)
  • G to A, chromosome 13 at 104,964,110 bp (GRCm38)
  • T to A, chromosome 14 at 79,476,913 bp (GRCm38)
  • C to T, chromosome 14 at 123,281,111 bp (GRCm38)
  • T to C, chromosome 15 at 99,521,216 bp (GRCm38)
  • C to A, chromosome 15 at 100,683,013 bp (GRCm38)
  • C to T, chromosome 16 at 13,664,655 bp (GRCm38)
  • G to A, chromosome 16 at 32,497,694 bp (GRCm38)
  • T to A, chromosome 17 at 13,804,008 bp (GRCm38)
  • C to T, chromosome 17 at 33,136,023 bp (GRCm38)
  • T to A, chromosome 17 at 78,841,017 bp (GRCm38)
  • A to T, chromosome 19 at 7,013,877 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9277 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069096-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.