Strain Name:
C57BL/6J-MtgxR9282Btlr/Mmmh
Stock Number:
069101-MU
Citation ID:
RRID:MMRRC_069101-MU
Other Names:
R9282 (G1)
Major Collection:

Strain Information

B4galt6
Name: UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 56386
VEGA: 18
HGNC: HGNC:929
Homologene: 3506
Vps41
Name: VPS41 HOPS complex subunit
Synonyms: mVam2, Vam2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218035
VEGA: 13
Homologene: 69165
Fam131a
Name: family with sequence similarity 131, member A
Synonyms: 2900046G09Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78408
Homologene: 82234
Ophn1
Name: oligophrenin 1
Synonyms: C130037N19Rik, Wtgr
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 94190
HGNC: HGNC:8148
Homologene: 1913
Pigv
Name: phosphatidylinositol glycan anchor biosynthesis, class V
Synonyms: D430024F16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230801
Homologene: 5354
Golga4
Name: golgin A4
Synonyms: golgin-245, Olp-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 54214
HGNC: HGNC:4427
Homologene: 68224
Usf1
Name: upstream transcription factor 1
Synonyms: upstream stimulatory factor, bHLHb11
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22278
Homologene: 31426
Rcl1
Name: RNA terminal phosphate cyclase-like 1
Synonyms: 2310040A02Rik, Rnac, RPCL1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 59028
VEGA: 19
Homologene: 4217
Utp6
Name: UTP6 small subunit processome component
Synonyms: 4732497O03Rik, HCA66
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216987
Homologene: 41265
Focad
Name: focadhesin
Synonyms: BC057079
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230393
Homologene: 9842
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: Itpr-1, Ip3r, Pcp1, InsP3R type I, P400, wblo, Pcp-1, IP3R1, opt
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Tshr
Name: thyroid stimulating hormone receptor
Synonyms: hypothroid, pet, hyt
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 22095
Homologene: 315
Atg16l1
Name: autophagy related 16 like 1
Synonyms: APG16L, 1500009K01Rik, WDR30
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 77040
Homologene: 41786
Psmg1
Name: proteasome (prosome, macropain) assembly chaperone 1
Synonyms: Dscr2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 56088
HGNC: HGNC:3043
Homologene: 2759
Mcm3ap
Name: minichromosome maintenance complex component 3 associated protein
Synonyms: GANP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 54387
VEGA: 10
HGNC: HGNC:6946
Homologene: 2902
Dcc
Name: DCC netrin 1 receptor
Synonyms: deleted in colorectal carcinoma, Igdcc1, C030036D22Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13176
HGNC: HGNC:2701
Homologene: 21081
Furin
Name: furin, paired basic amino acid cleaving enzyme
Synonyms: Fur, PACE, Pcsk3, SPC1, 9130404I01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18550
HGNC: HGNC:8568
Homologene: 1930
Pi4k2b
Name: phosphatidylinositol 4-kinase type 2 beta
Synonyms: 2610042N09Rik, 4933409G22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67073
Homologene: 32405
Aqp3
Name: aquaporin 3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11828
HGNC: HGNC:636
Homologene: 21025
Map3k2
Name: mitogen-activated protein kinase kinase kinase 2
Synonyms: 9630061B06Rik, Mekk2, MEK kinase 2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 26405
VEGA: 18
HGNC: HGNC:6854
Homologene: 74576
Tmco1
Name: transmembrane and coiled-coil domains 1
Synonyms: 4930403O06Rik, ESTM39, 1190006A08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68944
Homologene: 10384
Tlr3
Name: toll-like receptor 3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 142980
Homologene: 20696
Gdf5
Name: growth differentiation factor 5
Synonyms: brp, cartilage-derived morphogenetic protein-1, bp, CDMP-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14563
HGNC: HGNC:4220
Homologene: 468
Ttn
Name: titin
Synonyms: connectin, 1100001C23Rik, D330041I19Rik, D830007G01Rik, 2310074I15Rik, 2310036G12Rik, mdm, 2310057K23Rik, shru, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Lrrc37a
Name: leucine rich repeat containing 37A
Synonyms: LOC237954
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237954
Homologene: 138824
Katnal1
Name: katanin p60 subunit A-like 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231912
Homologene: 12942
Dnah14
Name: dynein, axonemal, heavy chain 14
Synonyms: Gm980, Dnahc14, A230079K17Rik, LOC381311
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240960
HGNC: HGNC:2945
Homologene: 90078
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: Mgr1, Gpr98, Mass1, VLGR1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110789
Homologene: 19815
Col5a2
Name: collagen, type V, alpha 2
Synonyms: 1110014L14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12832
HGNC: HGNC:2210
Homologene: 20119
Slc36a2
Name: solute carrier family 36 (proton/amino acid symporter), member 2
Synonyms: PAT2, Tramd1, A530067G19Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 246049
Homologene: 72100
Tdrd5
Name: tudor domain containing 5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 214575
Homologene: 18312
Ttc21b
Name: tetratricopeptide repeat domain 21B
Synonyms: aln, line 158, Thm1, 2410066K11Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 73668
Homologene: 57006
Fscb
Name: fibrous sheath CABYR binding protein
Synonyms: EG623046
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 623046
VEGA: 12
Homologene: 136275
Sorbs2
Name: sorbin and SH3 domain containing 2
Synonyms: 2010203O03Rik, 9430041O17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234214
Homologene: 83295
Mkrn2
Name: makorin, ring finger protein, 2
Synonyms: 2610002L04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67027
HGNC: HGNC:7113
Homologene: 8392
Vmn2r104
Name: vomeronasal 2, receptor 104
Synonyms: V2r7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22313
Homologene: 129751
Adam2
Name: a disintegrin and metallopeptidase domain 2
Synonyms: Ftnb, Ph30-beta, fertilin beta
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 11495
VEGA: 14
HGNC: HGNC:198
Homologene: 1127
Pla2g4a
Name: phospholipase A2, group IVA (cytosolic, calcium-dependent)
Synonyms: Type IV PLA2, Pla2g4, cytosolic phospholipase A2, cPLA2alpha, cPLA2, cytosolic PLA2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18783
HGNC: HGNC:9035
Homologene: 32059
Vmn2r94
Name: vomeronasal 2, receptor 94
Synonyms: EG665227
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 665227
Homologene: 129751
Aox4
Name: aldehyde oxidase 4
Synonyms: AOH2, 2310003G12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71872
Homologene: 70273
Tll2
Name: tolloid-like 2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 24087
VEGA: 19
Homologene: 56545
Fam186a
Name: family with sequence similarity 186, member A
Synonyms: LOC380973, 1700030F18Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72277
Tbc1d4
Name: TBC1 domain family, member 4
Synonyms: 5930406J04Rik, AS160
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 210789
Homologene: 45451
Adam24
Name: ADAM metallopeptidase domain 24
Synonyms: Dtgn5
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13526
HGNC: HGNC:203
Homologene: 137232
Pdzd7
Name: PDZ domain containing 7
Synonyms: EG435601, Pdzk7
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 100503041
Homologene: 129509
Or56b35
Name: olfactory receptor family 56 subfamily B member 35
Synonyms: GA_x6K02T2PBJ9-7942985-7943947, MOR40-3, Olfr689
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258745
Homologene: 128074
Abi3bp
Name: ABI family member 3 binding protein
Synonyms: TARSH, eratin, D930038M13Rik, 5033411B22Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 320712
VEGA: 16
Homologene: 134172
Ifit1bl1
Name: interferon induced protein with tetratricpeptide repeats 1B like 1
Synonyms: Gm14446
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 667373
Homologene: 78213
Vmn1r197
Name: vomeronasal 1 receptor 197
Synonyms: V1rh21
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171278
Homologene: 110880
Ganc
Name: glucosidase, alpha; neutral C
Synonyms: 5830445O15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76051
HGNC: HGNC:4139
Homologene: 25627
Cmtr2
Name: cap methyltransferase 2
Synonyms: Ftsjd1, C730036L12Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234728
Homologene: 10144
Slc23a4
Name: solute carrier family 23 member 4
Synonyms: 2010107G12Rik, LOC243753
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243753
Homologene: 134124
Tbc1d30
Name: TBC1 domain family, member 30
Synonyms: 4930505D03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74694
VEGA: 10
Homologene: 18930
Nradd
Name: neurotrophin receptor associated death domain
Synonyms: 2610311B09Rik, PLAIDD, NRDD
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67169
Homologene: 12091
Nicn1
Name: nicolin 1
Synonyms: 1500032A17Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66257
Homologene: 11936
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to G, chromosome 1 at 45,438,869 bp (GRCm38)
  • A to T, chromosome 1 at 58,245,869 bp (GRCm38)
  • T to A, chromosome 1 at 87,780,184 bp (GRCm38)
  • C to A, chromosome 1 at 149,871,456 bp (GRCm38)
  • T to C, chromosome 1 at 156,277,460 bp (GRCm38)
  • C to T, chromosome 1 at 167,308,563 bp (GRCm38)
  • T to A, chromosome 1 at 171,415,805 bp (GRCm38)
  • T to C, chromosome 1 at 181,814,512 bp (GRCm38)
  • A to G, chromosome 2 at 66,226,005 bp (GRCm38)
  • A to G, chromosome 2 at 76,900,517 bp (GRCm38)
  • A to G, chromosome 2 at 120,459,900 bp (GRCm38)
  • C to G, chromosome 2 at 155,941,995 bp (GRCm38)
  • A to G, chromosome 4 at 41,093,640 bp (GRCm38)
  • A to T, chromosome 4 at 88,196,822 bp (GRCm38)
  • A to T, chromosome 4 at 133,664,662 bp (GRCm38)
  • C to T, chromosome 5 at 52,743,537 bp (GRCm38)
  • A to T, chromosome 5 at 148,894,211 bp (GRCm38)
  • T to A, chromosome 6 at 34,978,926 bp (GRCm38)
  • T to A, chromosome 6 at 108,394,023 bp (GRCm38)
  • A to G, chromosome 6 at 115,614,573 bp (GRCm38)
  • C to A, chromosome 7 at 80,391,098 bp (GRCm38)
  • T to C, chromosome 7 at 105,314,574 bp (GRCm38)
  • T to A, chromosome 8 at 40,680,635 bp (GRCm38)
  • T to C, chromosome 8 at 45,398,606 bp (GRCm38)
  • T to G, chromosome 8 at 45,795,737 bp (GRCm38)
  • T to C, chromosome 8 at 110,222,345 bp (GRCm38)
  • C to T, chromosome 9 at 108,294,509 bp (GRCm38)
  • T to A, chromosome 9 at 110,621,683 bp (GRCm38)
  • T to C, chromosome 9 at 118,556,825 bp (GRCm38)
  • T to A, chromosome 10 at 76,506,518 bp (GRCm38)
  • T to C, chromosome 10 at 121,306,223 bp (GRCm38)
  • G to T, chromosome 11 at 55,170,011 bp (GRCm38)
  • A to T, chromosome 11 at 79,936,025 bp (GRCm38)
  • A to G, chromosome 11 at 103,500,807 bp (GRCm38)
  • T to G, chromosome 12 at 64,473,323 bp (GRCm38)
  • T to A, chromosome 12 at 91,507,744 bp (GRCm38)
  • G to T, chromosome 13 at 18,829,231 bp (GRCm38)
  • A to T, chromosome 13 at 22,328,438 bp (GRCm38)
  • A to G, chromosome 13 at 81,103,372 bp (GRCm38)
  • G to A, chromosome 14 at 66,029,789 bp (GRCm38)
  • A to G, chromosome 14 at 101,608,180 bp (GRCm38)
  • A to G, chromosome 15 at 99,941,998 bp (GRCm38)
  • G to A, chromosome 16 at 20,701,493 bp (GRCm38)
  • G to A, chromosome 16 at 56,620,504 bp (GRCm38)
  • T to C, chromosome 16 at 95,989,517 bp (GRCm38)
  • A to G, chromosome 17 at 18,277,489 bp (GRCm38)
  • A to T, chromosome 17 at 20,040,836 bp (GRCm38)
  • T to A, chromosome 18 at 20,692,452 bp (GRCm38)
  • T to A, chromosome 18 at 32,209,752 bp (GRCm38)
  • T to C, chromosome 18 at 71,682,178 bp (GRCm38)
  • T to C, chromosome 19 at 29,115,770 bp (GRCm38)
  • T to C, chromosome 19 at 34,594,508 bp (GRCm38)
  • T to A, chromosome 19 at 41,086,333 bp (GRCm38)
  • A to G, chromosome 19 at 45,040,183 bp (GRCm38)
  • G to A, chromosome X at 98,578,539 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9282 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069101-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.