Strain Name:
C57BL/6J-MtgxR9299Btlr/Mmmh
Stock Number:
069115-MU
Citation ID:
RRID:MMRRC_069115-MU
Other Names:
R9299 (G1)
Major Collection:

Strain Information

Frem2
Name: Fras1 related extracellular matrix protein 2
Synonyms: 8430406N05Rik, ne, b2b1562Clo, 6030440P17Rik, my
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242022
Homologene: 18454
Pik3cb
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Synonyms: p110beta, 1110001J02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74769
HGNC: HGNC:8976
Homologene: 21250
Abca12
Name: ATP-binding cassette, sub-family A member 12
Synonyms: 4833417A11Rik, 4832428G11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74591
Homologene: 45441
Tbce
Name: tubulin-specific chaperone E
Synonyms: 2610206D02Rik, C530005D02Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 70430
Homologene: 37744
Plekha1
Name: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
Synonyms: TAPP1, C920009D07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101476
Homologene: 11001
Thada
Name: thyroid adenoma associated
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240174
VEGA: 17
Homologene: 75175
Rnf40
Name: ring finger protein 40
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233900
Homologene: 8856
Cnot1
Name: CCR4-NOT transcription complex, subunit 1
Synonyms: 6030411K04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234594
HGNC: HGNC:7877
Homologene: 9453
Tep1
Name: telomerase associated protein 1
Synonyms: Tp1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21745
VEGA: 14
Homologene: 5157
Cyth1
Name: cytohesin 1
Synonyms: CTH-1, Pscd1, CLM1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19157
HGNC: HGNC:9501
Homologene: 31262
Il17re
Name: interleukin 17 receptor E
Synonyms: Il25r
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 57890
Homologene: 17109
Cyc1
Name: cytochrome c-1
Synonyms: 2610002H19Rik, Cyct1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66445
VEGA: 15
HGNC: HGNC:2579
Homologene: 55617
Slx9
Name: SLX9 ribosome biogenesis factor
Synonyms: 1810008A18Rik, Fam207a
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 108707
VEGA: 10
Homologene: 14384
1700017B05Rik
Name: RIKEN cDNA 1700017B05 gene
Synonyms: D9Ertd278e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74211
VEGA: 9
Homologene: 19283
Zbtb48
Name: zinc finger and BTB domain containing 48
Synonyms: Hkr3, 0610011D15Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100090
HGNC: HGNC:4930
Homologene: 3905
Mis18bp1
Name: MIS18 binding protein 1
Synonyms: C79407
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217653
Homologene: 10147
Dph1
Name: diphthamide biosynthesis 1
Synonyms: Dph2l1, Ovca1, 4930488F09Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 116905
HGNC: HGNC:3003
Homologene: 1059
Dnhd1
Name: dynein heavy chain domain 1
Synonyms: 8030491N06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77505
Homologene: 131117
Pla2g4e
Name: phospholipase A2, group IVE
Synonyms: 2310026J01Rik, Pla2epsilon
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329502
Homologene: 65339
Ksr2
Name: kinase suppressor of ras 2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 333050
Homologene: 45469
Cdc42bpa
Name: CDC42 binding protein kinase alpha
Synonyms: A930014J19Rik, DMPK-like
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226751
HGNC: HGNC:1737
Homologene: 55765
Pcdhb4
Name: protocadherin beta 4
Synonyms: PcdhbD, Pcdhb5A
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93875
HGNC: HGNC:8690
Homologene: 62176
Zfp385b
Name: zinc finger protein 385B
Synonyms: Zfp533, B830010L13Rik, C130013B13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241494
Homologene: 17606
Hsf5
Name: heat shock transcription factor family member 5
Synonyms: LOC327992
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327992
Homologene: 52701
Cyp4a10
Name: cytochrome P450, family 4, subfamily a, polypeptide 10
Synonyms: D4Rp1, Cyp4a, Msp-3, RP1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13117
HGNC: HGNC:2642
Homologene: 128044
Anapc15-ps
Name: anaphase promoting complex C subunit 15, pseudogene
Synonyms: Gm6843
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 628119
VEGA: 10
Poteg
Name: POTE ankyrin domain family, member G
Synonyms: 4921537P18Rik, 4930456F22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 70952
Homologene: 134158
Adamts9
Name: ADAM metallopeptidase with thrombospondin type 1 motif 9
Synonyms: 1810011L16Rik, UND3, Mhdaund4, Gsfund3, 8430403M15Rik, Mhdaund3, E030027K14Rik, UND4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101401
Homologene: 18821
Ahnak
Name: AHNAK nucleoprotein
Synonyms: DY6, 1110004P15Rik, 2310047C17Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Rev3l
Name: REV3 like, DNA directed polymerase zeta catalytic subunit
Synonyms: Sez4, Rev
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19714
HGNC: HGNC:9968
Homologene: 48147
Pcdhb22
Name: protocadherin beta 22
Synonyms: PcdhbV, Pcdhb15
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93893
HGNC: HGNC:8686
Homologene: 113752
Clec2e
Name: C-type lectin domain family 2, member e
Synonyms: Clra
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232409
Homologene: 131164
Thsd7a
Name: thrombospondin, type I, domain containing 7A
Synonyms: LOC330267
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330267
Homologene: 46582
St6galnac6
Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
Synonyms: ST6GalNAcVI, Siat7f
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 50935
Homologene: 8390
Cmklr1
Name: chemerin chemokine-like receptor 1
Synonyms: ChemR23, Gpcr27
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14747
HGNC: HGNC:2121
Homologene: 129967
Lrtm1
Name: leucine-rich repeats and transmembrane domains 1
Synonyms: A930016D02Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 319476
VEGA: 14
Homologene: 49635
Atp9a
Name: ATPase, class II, type 9A
Synonyms: Class II, IIa
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11981
Homologene: 69194
Capn13
Name: calpain 13
Synonyms: LOC381122
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381122
VEGA: 17
Homologene: 27026
Dok4
Name: docking protein 4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 114255
Homologene: 10009
Dpy19l3
Name: dpy-19 like C-mannosyltransferase 3
Synonyms: 9330164H19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233115
Homologene: 18692
Slc6a21
Name: solute carrier family 6 member 21
Synonyms: 1700039E15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76713
Homologene: 66347
Tmem82
Name: transmembrane protein 82
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 213989
Homologene: 27088
Ccdc7a
Name: coiled-coil domain containing 7A
Synonyms: 4930517G15Rik, 4930540C21Rik, Ccdc7
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74703
Homologene: 134760
Arhgap45
Name: Rho GTPase activating protein 45
Synonyms: Hmha1, 6330406L22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70719
Homologene: 69120
Ltk
Name: leukocyte tyrosine kinase
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17005
HGNC: HGNC:6721
Homologene: 130502
Fam24b
Name: family with sequence similarity 24 member B
Synonyms: 1700007K09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69318
Homologene: 78032
Or8b39
Name: olfactory receptor family 8 subfamily B member 39
Synonyms: GA_x6K02T2PVTD-31764095-31765024, Olfr887, MOR162-5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258415
Homologene: 133625
Socs1
Name: suppressor of cytokine signaling 1
Synonyms: STAT-induced STAT inhibitor 1, SSI-1, Cish1, Cish7, SOCS-1, JAB, JAK2-binding protein, JAK-binding protein
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12703
VEGA: 16
Homologene: 2776
Rrp8
Name: ribosomal RNA processing 8
Synonyms: 1500003O22Rik, 2900001K19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101867
Homologene: 5621
Nalf1
Name: NALCN channel auxiliary factor 1
Synonyms: Fam155a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 270028
Homologene: 83472
Eva1a
Name: eva-1 homolog A, regulator of programmed cell death
Synonyms: Fam176a, Tmem166
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232146
Homologene: 12969
Tmprss11a
Name: transmembrane protease, serine 11a
Synonyms: LOC194597
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 194597
Homologene: 62723
Paqr7
Name: progestin and adipoQ receptor family member VII
Synonyms: PGLP, mPR, 2310021M12Rik, Mpra
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 71904
Homologene: 12420
Gal3st3
Name: galactose-3-O-sulfotransferase 3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 545276
VEGA: 19
Homologene: 57198
Ifi211
Name: interferon activated gene 211
Synonyms: Ifi205b, Mnda
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381308
Homologene: 115929
Gm12888
Name: predicted gene 12888
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 545677
Homologene: 111034
Alad
Name: aminolevulinate, delta-, dehydratase
Synonyms: Lv
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17025
HGNC: HGNC:395
Homologene: 16
Krtap5-3
Name: keratin associated protein 5-3
Synonyms: A030007E19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77215
B020004C17Rik
Name: RIKEN cDNA B020004C17 gene
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 432860
VEGA: 14
Homologene: 128423
Gm17018
Name: predicted gene 17018
Type: Gene
Species: Mouse
Chromosome: 19
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 71,319,883 bp (GRCm38)
  • T to A, chromosome 1 at 173,907,722 bp (GRCm38)
  • C to A, chromosome 1 at 180,144,508 bp (GRCm38)
  • G to T, chromosome 2 at 32,612,333 bp (GRCm38)
  • A to T, chromosome 2 at 77,415,771 bp (GRCm38)
  • A to T, chromosome 2 at 119,754,240 bp (GRCm38)
  • T to A, chromosome 2 at 120,171,723 bp (GRCm38)
  • A to T, chromosome 2 at 168,712,746 bp (GRCm38)
  • T to C, chromosome 3 at 53,656,559 bp (GRCm38)
  • C to T, chromosome 4 at 62,511,523 bp (GRCm38)
  • A to G, chromosome 4 at 115,519,750 bp (GRCm38)
  • G to A, chromosome 4 at 121,324,847 bp (GRCm38)
  • A to G, chromosome 4 at 134,507,000 bp (GRCm38)
  • A to T, chromosome 4 at 141,616,550 bp (GRCm38)
  • T to C, chromosome 4 at 152,020,690 bp (GRCm38)
  • A to T, chromosome 5 at 86,422,502 bp (GRCm38)
  • G to C, chromosome 5 at 113,613,982 bp (GRCm38)
  • G to A, chromosome 5 at 117,747,334 bp (GRCm38)
  • A to G, chromosome 6 at 12,504,132 bp (GRCm38)
  • G to T, chromosome 6 at 82,092,066 bp (GRCm38)
  • A to G, chromosome 6 at 92,796,995 bp (GRCm38)
  • A to T, chromosome 6 at 113,464,010 bp (GRCm38)
  • A to C, chromosome 6 at 129,095,129 bp (GRCm38)
  • G to T, chromosome 7 at 35,725,327 bp (GRCm38)
  • T to C, chromosome 7 at 45,287,706 bp (GRCm38)
  • T to A, chromosome 7 at 105,720,599 bp (GRCm38)
  • T to C, chromosome 7 at 105,734,177 bp (GRCm38)
  • T to A, chromosome 7 at 127,589,000 bp (GRCm38)
  • T to A, chromosome 7 at 130,909,618 bp (GRCm38)
  • T to A, chromosome 7 at 131,326,220 bp (GRCm38)
  • T to A, chromosome 7 at 142,202,530 bp (GRCm38)
  • T to C, chromosome 8 at 9,770,156 bp (GRCm38)
  • A to G, chromosome 8 at 27,450,259 bp (GRCm38)
  • T to A, chromosome 8 at 94,866,841 bp (GRCm38)
  • T to C, chromosome 8 at 95,741,820 bp (GRCm38)
  • T to C, chromosome 8 at 128,889,838 bp (GRCm38)
  • A to G, chromosome 9 at 38,085,489 bp (GRCm38)
  • G to T, chromosome 9 at 57,256,509 bp (GRCm38)
  • A to G, chromosome 9 at 99,061,791 bp (GRCm38)
  • T to C, chromosome 10 at 39,848,003 bp (GRCm38)
  • C to A, chromosome 10 at 77,515,701 bp (GRCm38)
  • T to C, chromosome 10 at 80,026,731 bp (GRCm38)
  • C to A, chromosome 10 at 95,673,215 bp (GRCm38)
  • T to A, chromosome 11 at 75,179,796 bp (GRCm38)
  • T to A, chromosome 11 at 87,635,944 bp (GRCm38)
  • C to T, chromosome 11 at 118,169,011 bp (GRCm38)
  • A to T, chromosome 12 at 65,138,764 bp (GRCm38)
  • T to C, chromosome 13 at 14,019,813 bp (GRCm38)
  • C to T, chromosome 14 at 29,021,757 bp (GRCm38)
  • T to C, chromosome 14 at 50,844,531 bp (GRCm38)
  • A to T, chromosome 14 at 57,016,773 bp (GRCm38)
  • T to C, chromosome 15 at 76,344,306 bp (GRCm38)
  • T to C, chromosome 16 at 10,784,714 bp (GRCm38)
  • T to A, chromosome 17 at 73,326,472 bp (GRCm38)
  • T to C, chromosome 17 at 84,441,777 bp (GRCm38)
  • G to A, chromosome 18 at 37,309,211 bp (GRCm38)
  • G to T, chromosome 18 at 37,518,832 bp (GRCm38)
  • A to T, chromosome 19 at 5,306,840 bp (GRCm38)
  • G to A, chromosome 19 at 9,012,460 bp (GRCm38)
  • C to A, chromosome 19 at 45,577,570 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9299 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069115-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.