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Strain Name:
C57BL/6J-MtgxR9305Btlr/Mmmh
Stock Number:
069120-MU
Citation ID:
RRID:MMRRC_069120-MU
Other Names:
R9305 (G1)
Major Collection:

Strain Information

Casq2
Name: calsequestrin 2
Synonyms: cardiac calsequestrin, ESTM52, cCSQ, Csq2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12373
HGNC: HGNC:1513
Homologene: 20330
Hps5
Name: HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
Synonyms: ru-2, ruby eye 2, ru2, Hermansky-Pudlak syndrome 5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 246694
Homologene: 35333
Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: F4/80, DD7A5-7, TM7LN3, EGF-TM7, Ly71, Emr1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Foxa3
Name: forkhead box A3
Synonyms: Tcf-3g, Hnf3g, Hnf-3g, Tcf3g
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15377
HGNC: HGNC:5023
Homologene: 3308
Morc3
Name: microrchidia 3
Synonyms: 1110051N18Rik, D16Jhu32e, 1110051N18Rik, Zcwcc3
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 338467
Homologene: 32257
Ttc39b
Name: tetratricopeptide repeat domain 39B
Synonyms: 9130422G05Rik, 1810054D07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69863
Homologene: 25228
Ddx55
Name: DEAD box helicase 55
Synonyms: 2810021H22Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67848
Homologene: 12196
Gng2
Name: guanine nucleotide binding protein (G protein), gamma 2
Synonyms: 1110003P13Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14702
HGNC: HGNC:4404
Homologene: 40715
Bltp1
Name: bridge-like lipid transfer protein family member 1
Synonyms: Tweek, FSA, 4932438A13Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229227
Homologene: 52105
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, Lek1, mitosin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Parp4
Name: poly (ADP-ribose) polymerase family, member 4
Synonyms: VPARP, VAULT3, p193, PH5P, E230037B21Rik, Adprtl1, C030027K23Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 328417
HGNC: HGNC:271
Homologene: 124423
Orc3
Name: origin recognition complex, subunit 3
Synonyms: Orc3l
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 50793
HGNC: HGNC:8489
Homologene: 8225
Polg
Name: polymerase (DNA directed), gamma
Synonyms: Pol gamma, polymerase gamma, mitochondrial DNA polymerase gamma, mitochondrial DNA polymerase-gamma, Polga
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18975
HGNC: HGNC:9179
Homologene: 2016
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Cdh9
Name: cadherin 9
Synonyms: T1-cadherin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12565
HGNC: HGNC:1768
Homologene: 9450
Prune2
Name: prune homolog 2
Synonyms: 6330414G02Rik, A330102H22Rik, A230083H22Rik, Olfaxin
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 353211
VEGA: 19
Homologene: 18939
Rpl6
Name: ribosomal protein L6
Synonyms: Taxreb107
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19988
Homologene: 31001
Zfc3h1
Name: zinc finger, C3H1-type containing
Synonyms: Psrc2, Ccdc131
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216345
Homologene: 17017
Pcdhb18
Name: protocadherin beta 18
Synonyms: Pcdhb9, PcdhbR
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93889
Homologene: 137649
Abca16
Name: ATP-binding cassette, sub-family A member 16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233810
Homologene: 132942
Zbtb1
Name: zinc finger and BTB domain containing 1
Synonyms: C430003J21Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 268564
Homologene: 8974
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94109
Homologene: 69536
Abhd8
Name: abhydrolase domain containing 8
Synonyms: 0910001L24Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 64296
Homologene: 11188
Klb
Name: klotho beta
Synonyms: betaKlotho
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 83379
Homologene: 12820
Tmem26
Name: transmembrane protein 26
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 327766
VEGA: 10
Homologene: 14428
Lrrc43
Name: leucine rich repeat containing 43
Synonyms: LOC381741
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381741
Homologene: 17662
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Esyt1
Name: extended synaptotagmin-like protein 1
Synonyms: vp115, Mbc2, Fam62a
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 23943
VEGA: 10
Homologene: 40794
Adam34
Name: a disintegrin and metallopeptidase domain 34
Synonyms: testase 4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 252866
Homologene: 78104
Or8c20
Name: olfactory receptor family 8 subfamily C member 20
Synonyms: GA_x6K02T2PVTD-32037624-32038565, MOR170-3, Olfr898
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258871
VEGA: 9
Homologene: 133654
Fads2b
Name: fatty acid desaturase 2B
Synonyms: 4833423E24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228151
Homologene: 105643
Osbpl6
Name: oxysterol binding protein-like 6
Synonyms: ORP-6, 1110062M20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99031
Homologene: 101447
Serpina3i
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3I
Synonyms: 2B2, antitrypsin, alpha-1 antiproteinase, Gm6930
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 628900
HGNC: HGNC:16
Homologene: 115927
Vmn2r104
Name: vomeronasal 2, receptor 104
Synonyms: V2r7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22313
Homologene: 129751
Kynu
Name: kynureninase
Synonyms: 4432411A05Rik, L-kynurenine hydrolase
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70789
HGNC: HGNC:6469
Homologene: 2925
Atp9a
Name: ATPase, class II, type 9A
Synonyms: Class II, IIa
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11981
Homologene: 69194
Usp43
Name: ubiquitin specific peptidase 43
Synonyms: C630032K07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216835
Homologene: 129879
Togaram2
Name: TOG array regulator of axonemal microtubules 2
Synonyms: 4632412N22Rik, Fam179a
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320159
Homologene: 65315
Mief2
Name: mitochondrial elongation factor 2
Synonyms: LOC237781, Smcr7
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237781
Homologene: 27354
Serpinb8
Name: serine (or cysteine) peptidase inhibitor, clade B, member 8
Synonyms: Spi8, NK10, ovalbumin, CAP-2, CAP2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20725
HGNC: HGNC:8952
Homologene: 74445
Adamts17
Name: ADAM metallopeptidase with thrombospondin type 1 motif 17
Synonyms: AU023434
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233332
Homologene: 16373
Fam186b
Name: family with sequence similarity 186, member B
Synonyms: EG545136
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 545136
VEGA: 15
Homologene: 69502
Dpysl5
Name: dihydropyrimidinase-like 5
Synonyms: Crmp5, CRMP-5, CRAM
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 65254
Homologene: 41347
Aldh1b1
Name: aldehyde dehydrogenase 1 family, member B1
Synonyms: 2700007F14Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72535
HGNC: HGNC:407
Homologene: 115470
Clstn2
Name: calsyntenin 2
Synonyms: CS2, 2900042C18Rik, Cst-2, CSTN2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 64085
Homologene: 49698
Or2y3
Name: olfactory receptor family 2 subfamily Y member 3
Synonyms: MOR256-4, GA_x6K02T2PSCP-2531299-2530355, Olfr131
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258867
Homologene: 105889
Ppp2r2b
Name: protein phosphatase 2, regulatory subunit B, beta
Synonyms: 6330404L05Rik, PP2A-PR55B, PR55-BETA, SCA12, 2900026H06Rik, E130009M08Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 72930
HGNC: HGNC:9305
Homologene: 55833
Krt32
Name: keratin 32
Synonyms: mHa2, Krt1-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16670
HGNC: HGNC:6449
Homologene: 68246
Capn10
Name: calpain 10
Synonyms: Capn8
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 23830
HGNC: HGNC:1477
Homologene: 36323
Stx11
Name: syntaxin 11
Synonyms: 5830405C08Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74732
VEGA: 10
Homologene: 2792
Thoc3
Name: THO complex 3
Synonyms: 2410044K02Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 73666
Homologene: 12505
Chmp4c
Name: charged multivesicular body protein 4C
Synonyms: 2210015K02Rik, 2010012P02Rik, 2310010I16Rik, Snf7-3, chromatin modifying protein 4C
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66371
Homologene: 23544
Cacng2
Name: calcium channel, voltage-dependent, gamma subunit 2
Synonyms: stargazin, B230105C07Rik, B930041E13Rik, TARP gamma 2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12300
HGNC: HGNC:1406
Homologene: 4432
Cep295nl
Name: CEP295 N-terminal like
Synonyms: Ddc8, BC100451
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 58251
Homologene: 75164
Igf2
Name: insulin-like growth factor 2
Synonyms: Igf-2, Igf-II, Peg2, M6pr, Mpr
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16002
HGNC: HGNC:5466
Homologene: 510
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 92,943,943 bp (GRCm38)
  • T to C, chromosome 1 at 107,599,039 bp (GRCm38)
  • T to C, chromosome 1 at 189,660,074 bp (GRCm38)
  • A to T, chromosome 2 at 41,728,562 bp (GRCm38)
  • T to A, chromosome 2 at 43,679,756 bp (GRCm38)
  • T to A, chromosome 2 at 76,548,372 bp (GRCm38)
  • A to T, chromosome 2 at 85,500,305 bp (GRCm38)
  • A to T, chromosome 2 at 168,675,243 bp (GRCm38)
  • T to G, chromosome 3 at 10,389,914 bp (GRCm38)
  • A to G, chromosome 3 at 37,044,820 bp (GRCm38)
  • A to G, chromosome 3 at 102,145,384 bp (GRCm38)
  • G to A, chromosome 4 at 34,607,181 bp (GRCm38)
  • G to A, chromosome 4 at 45,803,811 bp (GRCm38)
  • A to G, chromosome 4 at 83,232,786 bp (GRCm38)
  • T to C, chromosome 5 at 30,791,615 bp (GRCm38)
  • T to A, chromosome 5 at 65,348,645 bp (GRCm38)
  • T to C, chromosome 5 at 121,208,453 bp (GRCm38)
  • C to T, chromosome 5 at 123,508,156 bp (GRCm38)
  • C to T, chromosome 5 at 124,566,949 bp (GRCm38)
  • A to G, chromosome 7 at 19,015,036 bp (GRCm38)
  • G to A, chromosome 7 at 46,789,195 bp (GRCm38)
  • T to C, chromosome 7 at 66,839,897 bp (GRCm38)
  • A to T, chromosome 7 at 79,456,112 bp (GRCm38)
  • A to G, chromosome 7 at 120,527,766 bp (GRCm38)
  • G to A, chromosome 7 at 142,654,416 bp (GRCm38)
  • G to T, chromosome 8 at 15,961,532 bp (GRCm38)
  • A to T, chromosome 8 at 43,651,379 bp (GRCm38)
  • A to G, chromosome 8 at 71,458,504 bp (GRCm38)
  • A to C, chromosome 9 at 38,349,085 bp (GRCm38)
  • T to A, chromosome 9 at 97,461,484 bp (GRCm38)
  • A to T, chromosome 10 at 12,941,820 bp (GRCm38)
  • G to A, chromosome 10 at 68,723,986 bp (GRCm38)
  • T to C, chromosome 10 at 82,060,680 bp (GRCm38)
  • A to G, chromosome 10 at 115,419,866 bp (GRCm38)
  • A to G, chromosome 10 at 128,519,519 bp (GRCm38)
  • C to A, chromosome 11 at 60,731,216 bp (GRCm38)
  • T to C, chromosome 11 at 67,876,519 bp (GRCm38)
  • T to C, chromosome 11 at 100,081,203 bp (GRCm38)
  • G to A, chromosome 11 at 118,333,940 bp (GRCm38)
  • A to G, chromosome 12 at 8,008,053 bp (GRCm38)
  • G to A, chromosome 12 at 76,385,999 bp (GRCm38)
  • T to C, chromosome 12 at 104,268,622 bp (GRCm38)
  • C to T, chromosome 13 at 54,460,185 bp (GRCm38)
  • G to T, chromosome 14 at 19,875,893 bp (GRCm38)
  • TG to T, chromosome 14 at 56,595,333 bp (GRCm38)
  • T to C, chromosome 14 at 56,614,767 bp (GRCm38)
  • T to A, chromosome 15 at 16,832,052 bp (GRCm38)
  • T to G, chromosome 15 at 78,013,342 bp (GRCm38)
  • G to A, chromosome 15 at 99,279,735 bp (GRCm38)
  • G to T, chromosome 16 at 93,870,414 bp (GRCm38)
  • A to G, chromosome 17 at 20,048,177 bp (GRCm38)
  • A to T, chromosome 17 at 38,082,738 bp (GRCm38)
  • A to G, chromosome 17 at 57,441,275 bp (GRCm38)
  • A to G, chromosome 17 at 71,689,413 bp (GRCm38)
  • A to C, chromosome 18 at 37,491,951 bp (GRCm38)
  • C to A, chromosome 18 at 42,645,960 bp (GRCm38)
  • A to G, chromosome 19 at 17,120,261 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9305 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069120-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.