Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR9305Btlr/Mmmh
Stock Number:
069120-MU
Citation ID:
RRID:MMRRC_069120-MU
Other Names:
R9305 (G1)
Major Collection:

Strain Information

Casq2
Name: calsequestrin 2
Synonyms: cardiac calsequestrin, ESTM52, cCSQ, Csq2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12373
HGNC: HGNC:1513
Homologene: 20330
Hps5
Name: HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
Synonyms: ru-2, ruby eye 2, ru2, Hermansky-Pudlak syndrome 5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 246694
Homologene: 35333
Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: F4/80, DD7A5-7, TM7LN3, EGF-TM7, Ly71, Emr1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Foxa3
Name: forkhead box A3
Synonyms: Tcf-3g, Hnf3g, Hnf-3g, Tcf3g
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15377
HGNC: HGNC:5023
Homologene: 3308
Morc3
Name: microrchidia 3
Synonyms: 1110051N18Rik, D16Jhu32e, 1110051N18Rik, Zcwcc3
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 338467
Homologene: 32257
Ttc39b
Name: tetratricopeptide repeat domain 39B
Synonyms: 9130422G05Rik, 1810054D07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69863
Homologene: 25228
Ddx55
Name: DEAD box helicase 55
Synonyms: 2810021H22Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67848
Homologene: 12196
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 92,943,943 bp (GRCm38)
  • T to C, chromosome 1 at 107,599,039 bp (GRCm38)
  • T to C, chromosome 1 at 189,660,074 bp (GRCm38)
  • A to T, chromosome 2 at 41,728,562 bp (GRCm38)
  • T to A, chromosome 2 at 43,679,756 bp (GRCm38)
  • T to A, chromosome 2 at 76,548,372 bp (GRCm38)
  • A to T, chromosome 2 at 85,500,305 bp (GRCm38)
  • A to T, chromosome 2 at 168,675,243 bp (GRCm38)
  • T to G, chromosome 3 at 10,389,914 bp (GRCm38)
  • A to G, chromosome 3 at 37,044,820 bp (GRCm38)
  • A to G, chromosome 3 at 102,145,384 bp (GRCm38)
  • G to A, chromosome 4 at 34,607,181 bp (GRCm38)
  • G to A, chromosome 4 at 45,803,811 bp (GRCm38)
  • A to G, chromosome 4 at 83,232,786 bp (GRCm38)
  • T to C, chromosome 5 at 30,791,615 bp (GRCm38)
  • T to A, chromosome 5 at 65,348,645 bp (GRCm38)
  • T to C, chromosome 5 at 121,208,453 bp (GRCm38)
  • C to T, chromosome 5 at 123,508,156 bp (GRCm38)
  • C to T, chromosome 5 at 124,566,949 bp (GRCm38)
  • A to G, chromosome 7 at 19,015,036 bp (GRCm38)
  • G to A, chromosome 7 at 46,789,195 bp (GRCm38)
  • T to C, chromosome 7 at 66,839,897 bp (GRCm38)
  • A to T, chromosome 7 at 79,456,112 bp (GRCm38)
  • A to G, chromosome 7 at 120,527,766 bp (GRCm38)
  • G to A, chromosome 7 at 142,654,416 bp (GRCm38)
  • G to T, chromosome 8 at 15,961,532 bp (GRCm38)
  • A to T, chromosome 8 at 43,651,379 bp (GRCm38)
  • A to G, chromosome 8 at 71,458,504 bp (GRCm38)
  • A to C, chromosome 9 at 38,349,085 bp (GRCm38)
  • T to A, chromosome 9 at 97,461,484 bp (GRCm38)
  • A to T, chromosome 10 at 12,941,820 bp (GRCm38)
  • G to A, chromosome 10 at 68,723,986 bp (GRCm38)
  • T to C, chromosome 10 at 82,060,680 bp (GRCm38)
  • A to G, chromosome 10 at 115,419,866 bp (GRCm38)
  • A to G, chromosome 10 at 128,519,519 bp (GRCm38)
  • C to A, chromosome 11 at 60,731,216 bp (GRCm38)
  • T to C, chromosome 11 at 67,876,519 bp (GRCm38)
  • T to C, chromosome 11 at 100,081,203 bp (GRCm38)
  • G to A, chromosome 11 at 118,333,940 bp (GRCm38)
  • A to G, chromosome 12 at 8,008,053 bp (GRCm38)
  • G to A, chromosome 12 at 76,385,999 bp (GRCm38)
  • T to C, chromosome 12 at 104,268,622 bp (GRCm38)
  • C to T, chromosome 13 at 54,460,185 bp (GRCm38)
  • G to T, chromosome 14 at 19,875,893 bp (GRCm38)
  • TG to T, chromosome 14 at 56,595,333 bp (GRCm38)
  • T to C, chromosome 14 at 56,614,767 bp (GRCm38)
  • T to A, chromosome 15 at 16,832,052 bp (GRCm38)
  • T to G, chromosome 15 at 78,013,342 bp (GRCm38)
  • G to A, chromosome 15 at 99,279,735 bp (GRCm38)
  • G to T, chromosome 16 at 93,870,414 bp (GRCm38)
  • A to G, chromosome 17 at 20,048,177 bp (GRCm38)
  • A to T, chromosome 17 at 38,082,738 bp (GRCm38)
  • A to G, chromosome 17 at 57,441,275 bp (GRCm38)
  • A to G, chromosome 17 at 71,689,413 bp (GRCm38)
  • A to C, chromosome 18 at 37,491,951 bp (GRCm38)
  • C to A, chromosome 18 at 42,645,960 bp (GRCm38)
  • A to G, chromosome 19 at 17,120,261 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9305 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069120-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.