Strain Name:
C57BL/6J-MtgxR9309Btlr/Mmmh
Stock Number:
069124-MU
Citation ID:
RRID:MMRRC_069124-MU
Other Names:
R9309 (G1)
Major Collection:

Strain Information

Angpt2
Name: angiopoietin 2
Synonyms: Ang-2, Ang2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11601
HGNC: HGNC:485
Homologene: 22401
Zfp423
Name: zinc finger protein 423
Synonyms: Ebfaz, Roaz, Zfp104, ataxia1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94187
Homologene: 9010
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: slip, DNAPDcs, DNA-PKcs, DNA-PK, DOXNPH, XRCC7, dxnph
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Mrpl39
Name: mitochondrial ribosomal protein L39
Synonyms: MRP-L5, Rpml5
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 27393
Homologene: 9679
Lemd2
Name: LEM domain containing 2
Synonyms: NET25, Lem2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224640
VEGA: 17
Homologene: 17136
Nf1
Name: neurofibromin 1
Synonyms: Mhdadsk9, neurofibromin, Nf-1, Dsk9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Rev1
Name: REV1, DNA directed polymerase
Synonyms: Rev1l, REV1, 1110027I23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 56210
Homologene: 32309
Ercc6
Name: excision repair cross-complementing rodent repair deficiency, complementation group 6
Synonyms: C130058G22Rik, CSB, CS group B correcting gene
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 319955
VEGA: 14
HGNC: HGNC:3438
Homologene: 133552
Urb2
Name: URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382038
Homologene: 8859
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 1810014J18Rik, 9030205D12Rik, A330063D19Rik, AD013
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 109151
Homologene: 11844
Cct8
Name: chaperonin containing TCP1 subunit 8
Synonyms: Tcpq, Cctq
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12469
HGNC: HGNC:1623
Homologene: 4802
Polr3a
Name: polymerase (RNA) III (DNA directed) polypeptide A
Synonyms: RPC1, RPC155, 9330175N20Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218832
VEGA: 14
Homologene: 5124
Zkscan1
Name: zinc finger with KRAB and SCAN domains 1
Synonyms: 9130423L19Rik, KOX18, 5930429A01Rik, 9230118B16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74570
Homologene: 34523
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Adam11
Name: a disintegrin and metallopeptidase domain 11
Synonyms: Mdc
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11488
HGNC: HGNC:189
Homologene: 7614
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: 2610100B16Rik, Odz3, Ten-m3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23965
Homologene: 22673
Patl1
Name: protein associated with topoisomerase II homolog 1 (yeast)
Synonyms: Pat1b
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225929
VEGA: 19
Homologene: 82269
Reln
Name: reelin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19699
HGNC: HGNC:9957
Homologene: 3699
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Ptpdc1
Name: protein tyrosine phosphatase domain containing 1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218232
VEGA: 13
Homologene: 17576
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 545030
Homologene: 83473
Ptpro
Name: protein tyrosine phosphatase receptor type O
Synonyms: D28, PTPROt, Ptpn15, PTP-oc, GLEPP1, PTP-U2, PTP-BK, PTP-phi
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19277
HGNC: HGNC:9678
Homologene: 21564
Lrrc7
Name: leucine rich repeat containing 7
Synonyms: densin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242274
Homologene: 10817
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: OTTMUSG00000005786, LOC380698
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Klc4
Name: kinesin light chain 4
Synonyms: Knsl8, 1200014P03Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74764
VEGA: 17
Homologene: 12584
Or5h18
Name: olfactory receptor family 5 subfamily H member 18
Synonyms: Olfr186, GA_x54KRFPKG5P-55257214-55256285, MOR183-9
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258318
Homologene: 133671
Ak9
Name: adenylate kinase 9
Synonyms: Akd2, LOC215946, Akd1, Gm7127
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 633979
Homologene: 67934
Tom1l1
Name: target of myb1-like 1 (chicken)
Synonyms: 2310045L10Rik, Srcasm
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71943
Homologene: 38055
Btn2a2
Name: butyrophilin, subfamily 2, member A2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238555
Homologene: 56012
Ctnnb1
Name: catenin beta 1
Synonyms: beta catenin, beta-catenin, catenin (cadherin associated protein), beta 1, Catnb
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12387
HGNC: HGNC:2514
Homologene: 1434
Spata31h1
Name: SPATA31 subfamily H member 1
Synonyms: 4932415D10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 102635990
VEGA: 10
Homologene: 82476
Tex48
Name: testis expressed 48
Synonyms: 1700018C11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 75524
Homologene: 87066
Lrit2
Name: leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
Synonyms: A930010E21Rik, Lrrc22
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239038
VEGA: 14
Homologene: 18292
Bpifa6
Name: BPI fold containing family A, member 6
Synonyms: Gm5840
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 545477
Homologene: 129594
Pcdhb19
Name: protocadherin beta 19
Synonyms: Pcdhb11, PcdhbS
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93890
Homologene: 128411
Cdc20b
Name: cell division cycle 20B
Synonyms: EG622422, EG238896
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238896
Homologene: 65056
Cfh
Name: complement component factor h
Synonyms: Mud-1, Sas-1, Sas1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12628
HGNC: HGNC:4883
Homologene: 20086
Acy3
Name: aminoacylase 3
Synonyms: AA3, 0610006H10Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 71670
VEGA: 19
Homologene: 12401
Cobll1
Name: Cobl-like 1
Synonyms: Coblr1, D430044D16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 319876
Homologene: 8933
Try10
Name: trypsin 10
Synonyms: trypsinogen 10
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 436522
Homologene: 134623
Msln
Name: mesothelin
Synonyms: megakaryocyte potentiating factor, MPF
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 56047
VEGA: 17
HGNC: HGNC:7371
Homologene: 4249
Itgb5
Name: integrin beta 5
Synonyms: ESTM23, beta-5, beta5, [b]5B, [b]5, [b]5A, [b]-5
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 16419
HGNC: HGNC:6160
Homologene: 20511
Zeb2
Name: zinc finger E-box binding homeobox 2
Synonyms: 9130203F04Rik, SIP1, Zfhx1b, Zfx1b, D130016B08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 24136
Homologene: 8868
Cope
Name: coatomer protein complex, subunit epsilon
Synonyms: 1110005D17Rik, Cope1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 59042
HGNC: HGNC:2234
Homologene: 5254
Brsk1
Name: BR serine/threonine kinase 1
Synonyms: SAD-B, LOC381979
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381979
Homologene: 57169
Zscan4b
Name: zinc finger and SCAN domain containing 4B
Synonyms: EG665780
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 665780
Homologene: 85986
Haao
Name: 3-hydroxyanthranilate 3,4-dioxygenase
Synonyms: 0610012J07Rik, 3-HAOxase, 0610007K21Rik, 3-HAO, 3HAO
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 107766
VEGA: 17
HGNC: HGNC:4796
Homologene: 8148
Hbq1b
Name: hemoglobin, theta 1B
Synonyms: F830116E18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 544763
HGNC: HGNC:4833
Homologene: 3895
Optc
Name: opticin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269120
HGNC: HGNC:8158
Homologene: 8652
Or14j9
Name: olfactory receptor family 14 subfamily J member 9
Synonyms: MOR218-4, Olfr112, GA_x6K02T2PSCP-2023769-2022807, 4930580F03Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258096
Or7g26
Name: olfactory receptor family 7 subfamily G member 26
Synonyms: Olfr844, GA_x6K02T2PVTD-13056760-13057689, MOR153-3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 100503048
HGNC: HGNC:8466
2310003L06Rik
Name: RIKEN cDNA 2310003L06 gene
Type: Gene
Species: Mouse
Chromosome: 5
H2-M10.1
Name: histocompatibility 2, M region locus 10.1
Synonyms: 9.5H
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14985
Homologene: 117973
Ttc6
Name: tetratricopeptide repeat domain 6
Synonyms: EG639426, AU024163, 4921506M07Rik, Gm9813, LOC217602
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 70846
Homologene: 78002
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 38,054,864 bp (GRCm38)
  • G to T, chromosome 1 at 133,897,944 bp (GRCm38)
  • A to T, chromosome 1 at 140,154,511 bp (GRCm38)
  • T to A, chromosome 2 at 45,002,563 bp (GRCm38)
  • A to G, chromosome 2 at 65,125,927 bp (GRCm38)
  • A to T, chromosome 2 at 153,992,287 bp (GRCm38)
  • C to T, chromosome 3 at 158,209,724 bp (GRCm38)
  • G to T, chromosome 4 at 63,611,868 bp (GRCm38)
  • A to T, chromosome 5 at 21,971,868 bp (GRCm38)
  • C to A, chromosome 5 at 87,972,473 bp (GRCm38)
  • A to G, chromosome 5 at 138,093,404 bp (GRCm38)
  • G to T, chromosome 6 at 41,356,625 bp (GRCm38)
  • G to A, chromosome 6 at 137,454,658 bp (GRCm38)
  • T to C, chromosome 7 at 4,706,119 bp (GRCm38)
  • G to T, chromosome 7 at 10,901,929 bp (GRCm38)
  • A to T, chromosome 8 at 18,699,156 bp (GRCm38)
  • A to T, chromosome 8 at 48,298,937 bp (GRCm38)
  • T to C, chromosome 8 at 70,302,832 bp (GRCm38)
  • T to A, chromosome 8 at 87,783,060 bp (GRCm38)
  • G to A, chromosome 8 at 91,006,691 bp (GRCm38)
  • T to C, chromosome 8 at 124,028,070 bp (GRCm38)
  • A to G, chromosome 9 at 19,319,148 bp (GRCm38)
  • A to T, chromosome 9 at 120,955,438 bp (GRCm38)
  • T to C, chromosome 10 at 41,316,368 bp (GRCm38)
  • T to C, chromosome 10 at 82,295,152 bp (GRCm38)
  • G to A, chromosome 11 at 32,287,408 bp (GRCm38)
  • C to T, chromosome 11 at 59,052,511 bp (GRCm38)
  • T to G, chromosome 11 at 79,468,769 bp (GRCm38)
  • TTGCTGCTGCTGCTGCTG to TTGCTGCTGCTGCTG, chromosome 11 at 90,649,822 bp (GRCm38)
  • C to T, chromosome 11 at 102,772,884 bp (GRCm38)
  • A to G, chromosome 12 at 57,706,863 bp (GRCm38)
  • T to G, chromosome 13 at 11,706,692 bp (GRCm38)
  • T to A, chromosome 13 at 23,478,811 bp (GRCm38)
  • A to G, chromosome 13 at 48,583,131 bp (GRCm38)
  • T to C, chromosome 13 at 113,079,938 bp (GRCm38)
  • T to G, chromosome 14 at 24,459,999 bp (GRCm38)
  • T to A, chromosome 14 at 32,518,947 bp (GRCm38)
  • C to T, chromosome 14 at 33,095,356 bp (GRCm38)
  • C to A, chromosome 14 at 37,071,891 bp (GRCm38)
  • G to A, chromosome 15 at 44,536,893 bp (GRCm38)
  • C to A, chromosome 16 at 15,708,928 bp (GRCm38)
  • T to C, chromosome 16 at 33,920,046 bp (GRCm38)
  • A to G, chromosome 16 at 59,027,823 bp (GRCm38)
  • C to T, chromosome 16 at 84,735,183 bp (GRCm38)
  • G to A, chromosome 16 at 87,485,704 bp (GRCm38)
  • A to G, chromosome 17 at 25,751,174 bp (GRCm38)
  • A to T, chromosome 17 at 27,192,962 bp (GRCm38)
  • T to C, chromosome 17 at 36,325,633 bp (GRCm38)
  • A to G, chromosome 17 at 37,564,158 bp (GRCm38)
  • T to C, chromosome 17 at 46,636,624 bp (GRCm38)
  • T to C, chromosome 17 at 83,838,841 bp (GRCm38)
  • T to C, chromosome 18 at 37,498,805 bp (GRCm38)
  • C to T, chromosome 19 at 3,988,451 bp (GRCm38)
  • C to A, chromosome 19 at 11,935,718 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9309 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069124-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.