Strain Name:
C57BL/6J-MtgxR9317Btlr/Mmmh
Stock Number:
069130-MU
Citation ID:
RRID:MMRRC_069130-MU
Other Names:
R9317 (G1)
Major Collection:

Strain Information

Ptprk
Name: protein tyrosine phosphatase receptor type K
Synonyms: RPTPkappa, PTPk
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19272
VEGA: 10
HGNC: HGNC:9674
Homologene: 55693
Dnmt1
Name: DNA methyltransferase 1
Synonyms: Dnmt1o, MTase, Cxxc9, MommeD2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13433
VEGA: 9
HGNC: HGNC:2976
Homologene: 124071
Usp48
Name: ubiquitin specific peptidase 48
Synonyms: 2810449C13Rik, Usp31, D330022K21Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 170707
Homologene: 12988
Ilf3
Name: interleukin enhancer binding factor 3
Synonyms: NF90
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 16201
VEGA: 9
HGNC: HGNC:6038
Homologene: 7785
Cdc37l1
Name: cell division cycle 37-like 1
Synonyms: Harc, Hsp90-associating relative of Cdc37, 2700033A15Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 67072
VEGA: 19
Homologene: 9912
Hspa5
Name: heat shock protein 5
Synonyms: baffled, D2Wsu17e, Hsce70, 78kDa, Grp78, D2Wsu141e, XAP-1 antigen, Sez7, mBiP, Bip
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14828
HGNC: HGNC:5238
Homologene: 3908
Wdr12
Name: WD repeat domain 12
Synonyms: Ytm1, Ytm1p, 4933402C23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 57750
Homologene: 10098
Rpf1
Name: ribosome production factor 1 homolog
Synonyms: Bxdc5, 2310066N05Rik, 2210420E24Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70285
Homologene: 68728
Tmtc3
Name: transmembrane and tetratricopeptide repeat containing 3
Synonyms: 9130014E20Rik, B130008E12Rik, mSmile
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237500
Homologene: 27616
Gmeb1
Name: glucocorticoid modulatory element binding protein 1
Synonyms: 1110050A04Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56809
HGNC: HGNC:4370
Homologene: 10647
Zfp953
Name: zinc finger protein 953
Synonyms: E130120F12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 629016
Prune2
Name: prune homolog 2
Synonyms: A330102H22Rik, Olfaxin, 6330414G02Rik, A230083H22Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 353211
VEGA: 19
Homologene: 18939
Rmdn3
Name: regulator of microtubule dynamics 3
Synonyms: Fam82a2, 1200015F23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67809
Homologene: 34926
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: LOC224126, 2210407G14Rik, E530005C20Rik, Hapip
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Qrfprl
Name: pyroglutamylated RFamide peptide receptor like
Synonyms: C130060K24Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243407
Homologene: 135976
Cd68
Name: CD68 antigen
Synonyms: Scard1, gp110, Lamp4, macrosialin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12514
HGNC: HGNC:1693
Homologene: 955
Trpc1
Name: transient receptor potential cation channel, subfamily C, member 1
Synonyms: Mtrp1, Trp1, Trrp1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22063
Homologene: 2478
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 665700
Homologene: 90772
Ttn
Name: titin
Synonyms: mdm, D830007G01Rik, shru, 1100001C23Rik, D330041I19Rik, 2310057K23Rik, 2310036G12Rik, 2310074I15Rik, L56, connectin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Unc13c
Name: unc-13 homolog C
Synonyms: Munc13-3, D9Ertd414e, Unc13h3, 1500037O19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208898
Homologene: 45443
Gpr158
Name: G protein-coupled receptor 158
Synonyms: 5330427M13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241263
Homologene: 19381
Grik5
Name: glutamate receptor, ionotropic, kainate 5 (gamma 2)
Synonyms: KA2, GluRgamma2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14809
HGNC: HGNC:4583
Homologene: 1578
Vmn2r72
Name: vomeronasal 2, receptor 72
Synonyms: EG244114, Vmn2r72-ps
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244114
Homologene: 115466
Gli3
Name: GLI-Kruppel family member GLI3
Synonyms: brachyphalangy, Bph
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14634
HGNC: HGNC:4319
Homologene: 139
Cyp3a57
Name: cytochrome P450, family 3, subfamily a, polypeptide 57
Synonyms: EG622127
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 622127
Homologene: 135775
Smarca2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Synonyms: brm, Snf2l2, 2610209L14Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 67155
Homologene: 2308
Apcdd1
Name: adenomatosis polyposis coli down-regulated 1
Synonyms: Drapc1, EIG180
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 494504
VEGA: 18
Homologene: 77420
Prr5
Name: proline rich 5 (renal)
Synonyms: C030017C09Rik, Protor-1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 109270
Homologene: 17132
Or2n1d
Name: olfactory receptor family 2 subfamily N member 1D
Synonyms: GA_x6K02T2PSCP-2779375-2780313, Olfr136, MOR256-7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258803
Homologene: 119758
Negr1
Name: neuronal growth regulator 1
Synonyms: neurotractin, Ntra, 5330422G01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 320840
Homologene: 41447
Or8b52
Name: olfactory receptor family 8 subfamily B member 52
Synonyms: GA_x6K02T2PVTD-32368166-32367237, MOR168-2P, Olfr917
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258183
VEGA: 9
Senp5
Name: SUMO/sentrin specific peptidase 5
Synonyms: 6230429P13Rik, A730063F07Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 320213
Homologene: 17647
Adad2
Name: adenosine deaminase domain containing 2
Synonyms: 4930403J07Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 75773
Homologene: 16392
Taar8a
Name: trace amine-associated receptor 8A
Synonyms: LOC215859
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215859
Homologene: 77586
C1qbp
Name: complement component 1, q subcomponent binding protein
Synonyms: D11Wsu182e, P32, HABP1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12261
HGNC: HGNC:1243
Homologene: 31023
Sult2a6
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6
Synonyms: Gm6957
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 629219
Homologene: 37741
Sprr2j-ps
Name: small proline-rich protein 2J, pseudogene
Synonyms: Sprr2j
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20764
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to A, chromosome 1 at 60,089,296 bp (GRCm38)
  • T to C, chromosome 2 at 21,827,226 bp (GRCm38)
  • G to A, chromosome 2 at 31,460,316 bp (GRCm38)
  • G to T, chromosome 2 at 34,776,058 bp (GRCm38)
  • T to C, chromosome 2 at 76,811,355 bp (GRCm38)
  • G to A, chromosome 2 at 119,156,510 bp (GRCm38)
  • T to A, chromosome 3 at 92,418,871 bp (GRCm38)
  • A to G, chromosome 3 at 146,512,261 bp (GRCm38)
  • T to A, chromosome 3 at 157,198,444 bp (GRCm38)
  • A to T, chromosome 4 at 132,226,038 bp (GRCm38)
  • G to A, chromosome 4 at 137,613,685 bp (GRCm38)
  • T to C, chromosome 5 at 145,372,611 bp (GRCm38)
  • A to C, chromosome 6 at 65,447,384 bp (GRCm38)
  • A to T, chromosome 7 at 14,236,690 bp (GRCm38)
  • A to G, chromosome 7 at 25,046,235 bp (GRCm38)
  • A to T, chromosome 7 at 85,754,814 bp (GRCm38)
  • T to C, chromosome 8 at 119,615,441 bp (GRCm38)
  • A to G, chromosome 9 at 20,918,279 bp (GRCm38)
  • A to G, chromosome 9 at 21,396,126 bp (GRCm38)
  • T to A, chromosome 9 at 38,665,359 bp (GRCm38)
  • A to G, chromosome 9 at 73,540,380 bp (GRCm38)
  • A to G, chromosome 9 at 95,721,222 bp (GRCm38)
  • T to C, chromosome 10 at 24,076,855 bp (GRCm38)
  • A to G, chromosome 10 at 28,354,735 bp (GRCm38)
  • T to C, chromosome 10 at 100,466,034 bp (GRCm38)
  • C to T, chromosome 11 at 69,665,034 bp (GRCm38)
  • T to C, chromosome 11 at 70,978,103 bp (GRCm38)
  • T to A, chromosome 13 at 15,715,073 bp (GRCm38)
  • T to C, chromosome 13 at 67,343,393 bp (GRCm38)
  • C to T, chromosome 15 at 84,699,123 bp (GRCm38)
  • A to C, chromosome 16 at 31,983,572 bp (GRCm38)
  • T to C, chromosome 16 at 34,013,675 bp (GRCm38)
  • A to T, chromosome 17 at 38,335,429 bp (GRCm38)
  • C to T, chromosome 18 at 62,922,660 bp (GRCm38)
  • T to A, chromosome 19 at 17,121,670 bp (GRCm38)
  • T to C, chromosome 19 at 26,759,879 bp (GRCm38)
  • T to G, chromosome 19 at 28,995,118 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9317 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069130-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.