Strain Name:
C57BL/6J-MtgxR9319Btlr/Mmmh
Stock Number:
069132-MU
Citation ID:
RRID:MMRRC_069132-MU
Other Names:
R9319 (G1)
Major Collection:

Strain Information

Pax3
Name: paired box 3
Synonyms: Splchl2, Pax-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18505
HGNC: HGNC:8617
Homologene: 22494
Nrg1
Name: neuregulin 1
Synonyms: GGFII, HGL, Hgl, SMDF, GGF, HRG, D230005F13Rik, ARIA, HRGalpha, heregulin, 6030402G23Rik, NDF
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 211323
HGNC: HGNC:7997
Homologene: 138451
Dlgap4
Name: DLG associated protein 4
Synonyms: DAP4, PSD-95/SAP90 binding protein 4, Sapap4, WBP16, SAP90/PSD-95-associated protein 4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228836
Homologene: 8935
Cobl
Name: cordon-bleu WH2 repeat
Synonyms: C530045F18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12808
Homologene: 9058
Akap13
Name: A kinase anchor protein 13
Synonyms: 5730522G15Rik, 1700026G02Rik, PROTO-LB, Ht31, PROTO-LBC, 5830460E08Rik, AKAP-Lbc
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75547
HGNC: HGNC:371
Homologene: 4903
Dhx15
Name: DEAH-box helicase 15
Synonyms: DEAH (Asp-Glu-Ala-His) box polypeptide 15, Ddx15, HRH2, DBP1, mDEAH9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13204
HGNC: HGNC:2738
Homologene: 1040
Plk1
Name: polo like kinase 1
Synonyms: STPK13, Plk
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18817
HGNC: HGNC:9077
Homologene: 3690
Ipo13
Name: importin 13
Synonyms: Imp13, Kap13
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230673
Homologene: 40968
Kif2c
Name: kinesin family member 2C
Synonyms: 4930402F02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 73804
HGNC: HGNC:6393
Homologene: 21355
Mcm3ap
Name: minichromosome maintenance complex component 3 associated protein
Synonyms: GANP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 54387
VEGA: 10
HGNC: HGNC:6946
Homologene: 2902
Ntng2
Name: netrin G2
Synonyms: Lmnt2, 2610016D08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 171171
Homologene: 13053
Cttn
Name: cortactin
Synonyms: Ems1, 1110020L01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13043
HGNC: HGNC:3338
Homologene: 3834
Thap1
Name: THAP domain containing, apoptosis associated protein 1
Synonyms: 4833431A01Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 73754
Homologene: 10005
Snrnp40
Name: small nuclear ribonucleoprotein 40 (U5)
Synonyms: 0610009C03Rik, Wdr57
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66585
Homologene: 3538
Dlst
Name: dihydrolipoamide S-succinyltransferase
Synonyms: 4632413C10Rik, 4930529O08Rik, 1600017E01Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 78920
VEGA: 12
HGNC: HGNC:2911
Homologene: 1456
Tpbg
Name: trophoblast glycoprotein
Synonyms: 5T4, 5T4 oncofetal antigen
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 21983
Homologene: 4859
Glipr1l1
Name: GLI pathogenesis-related 1 like 1
Synonyms: 1700011E04Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 69286
VEGA: 10
Homologene: 83452
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Ino80
Name: INO80 complex subunit
Synonyms: 2310079N15Rik, INO80, Inoc1, 4632409L19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68142
Homologene: 75070
Pias4
Name: protein inhibitor of activated STAT 4
Synonyms: PIASy
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 59004
Homologene: 104136
Vac14
Name: Vac14 homolog (S. cerevisiae)
Synonyms: ingls, Trx, D8Wsu151e, Tax1bp2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234729
Homologene: 6528
Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Synonyms: TRPC7, Trrp7, 9830168K16Rik, LTRPC2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 28240
Homologene: 20709
Mturn
Name: maturin, neural progenitor differentiation regulator homolog (Xenopus)
Synonyms: B230212L03Rik, 2410066E13Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68235
Cd22
Name: CD22 antigen
Synonyms: Lyb8, Lyb-8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12483
HGNC: HGNC:1643
Homologene: 31052
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Mcoln2
Name: mucolipin 2
Synonyms: mucolipidin 2, 3300002C04Rik, TRPML2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 68279
Homologene: 12258
Elovl3
Name: ELOVL fatty acid elongase 3
Synonyms: elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3, CIN-2, Cig30
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12686
Homologene: 69006
Epas1
Name: endothelial PAS domain protein 1
Synonyms: HRF, MOP2, hypoxia inducible transcription factor 2alpha, HIF-2alpha, HLF, Hif like protein, HIF2A, bHLHe73
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13819
VEGA: 17
HGNC: HGNC:3374
Homologene: 1095
Dsg1b
Name: desmoglein 1 beta
Synonyms: Dsg5
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225256
HGNC: HGNC:3048
Homologene: 1463
Fads2b
Name: fatty acid desaturase 2B
Synonyms: 4833423E24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228151
Homologene: 105643
Fanca
Name: Fanconi anemia, complementation group A
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14087
HGNC: HGNC:3582
Homologene: 108
Odad3
Name: outer dynein arm docking complex subunit 3
Synonyms: C330001K17Rik, b2b1885Clo, Ccdc151
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77609
VEGA: 9
Homologene: 16533
Rsph10b
Name: radial spoke head 10 homolog B (Chlamydomonas)
Synonyms: 4930526H21Rik, Rsph10b2
Type: Gene
Species: Mouse
Chromosome: 5
Homologene: 18321
Apcdd1
Name: adenomatosis polyposis coli down-regulated 1
Synonyms: EIG180, Drapc1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 494504
VEGA: 18
Homologene: 77420
Tmx3
Name: thioredoxin-related transmembrane protein 3
Synonyms: 6430411B10Rik, A730024F05Rik, Txndc10
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67988
VEGA: 18
Homologene: 10381
Sptlc3
Name: serine palmitoyltransferase, long chain base subunit 3
Synonyms: C130053K05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228677
Homologene: 105590
Scart1
Name: scavenger receptor family member expressed on T cells 1
Synonyms: E430002D04Rik, Cd163l1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244233
Homologene: 129778
Ankrd6
Name: ankyrin repeat domain 6
Synonyms: diversin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 140577
Homologene: 8967
4930590J08Rik
Name: RIKEN cDNA 4930590J08 gene
Synonyms: LOC381798
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 381798
Homologene: 49985
Vmn2r71
Name: vomeronasal 2, receptor 71
Synonyms: EG233445
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233445
Homologene: 115466
Ltk
Name: leukocyte tyrosine kinase
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17005
HGNC: HGNC:6721
Homologene: 130502
Troap
Name: trophinin associated protein
Synonyms: tastin, E130301L11Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 78733
VEGA: 15
Homologene: 28697
Dnah7c
Name: dynein, axonemal, heavy chain 7C
Synonyms: Dnahc7c
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 100101919
Homologene: 41287
Camk2b
Name: calcium/calmodulin-dependent protein kinase II, beta
Synonyms: CaMK II
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12323
HGNC: HGNC:1461
Homologene: 111050
Lrrc61
Name: leucine rich repeat containing 61
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243371
Homologene: 41538
Chst13
Name: carbohydrate sulfotransferase 13
Synonyms: 1110067M19Rik, Chst13, C4ST-3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71797
Homologene: 44360
Snu13
Name: SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
Synonyms: FA-1, Fta1, Fertilization antigen-1, Ssfa1, Nhp2l1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20826
HGNC: HGNC:7819
Homologene: 3672
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 46,482,008 bp (GRCm38)
  • T to A, chromosome 1 at 78,103,442 bp (GRCm38)
  • T to C, chromosome 2 at 29,201,109 bp (GRCm38)
  • G to A, chromosome 2 at 85,490,413 bp (GRCm38)
  • T to C, chromosome 2 at 119,374,524 bp (GRCm38)
  • C to A, chromosome 2 at 119,759,615 bp (GRCm38)
  • C to T, chromosome 2 at 139,636,810 bp (GRCm38)
  • G to T, chromosome 2 at 156,704,594 bp (GRCm38)
  • T to A, chromosome 3 at 146,169,936 bp (GRCm38)
  • C to T, chromosome 4 at 32,806,324 bp (GRCm38)
  • T to C, chromosome 4 at 117,178,248 bp (GRCm38)
  • T to C, chromosome 4 at 117,912,388 bp (GRCm38)
  • T to C, chromosome 4 at 130,362,752 bp (GRCm38)
  • G to A, chromosome 5 at 52,184,851 bp (GRCm38)
  • A to C, chromosome 5 at 143,966,519 bp (GRCm38)
  • C to A, chromosome 6 at 48,568,294 bp (GRCm38)
  • T to A, chromosome 6 at 54,681,795 bp (GRCm38)
  • G to A, chromosome 6 at 90,309,524 bp (GRCm38)
  • A to G, chromosome 6 at 91,945,465 bp (GRCm38)
  • T to A, chromosome 7 at 30,869,904 bp (GRCm38)
  • A to G, chromosome 7 at 75,609,088 bp (GRCm38)
  • C to T, chromosome 7 at 85,624,486 bp (GRCm38)
  • C to A, chromosome 7 at 122,168,899 bp (GRCm38)
  • C to T, chromosome 7 at 140,228,027 bp (GRCm38)
  • T to C, chromosome 7 at 144,463,363 bp (GRCm38)
  • CAGCATCTGCTCGGAGCA to CAGCA, chromosome 8 at 26,160,856 bp (GRCm38)
  • T to C, chromosome 8 at 31,833,176 bp (GRCm38)
  • T to A, chromosome 8 at 44,953,023 bp (GRCm38)
  • T to A, chromosome 8 at 110,634,386 bp (GRCm38)
  • T to C, chromosome 8 at 123,291,451 bp (GRCm38)
  • T to C, chromosome 9 at 21,994,907 bp (GRCm38)
  • C to T, chromosome 9 at 85,843,938 bp (GRCm38)
  • A to G, chromosome 10 at 76,482,804 bp (GRCm38)
  • G to A, chromosome 10 at 77,942,942 bp (GRCm38)
  • A to T, chromosome 10 at 77,949,198 bp (GRCm38)
  • G to A, chromosome 10 at 81,155,916 bp (GRCm38)
  • G to T, chromosome 10 at 112,062,217 bp (GRCm38)
  • G to T, chromosome 11 at 5,977,814 bp (GRCm38)
  • A to T, chromosome 11 at 12,253,648 bp (GRCm38)
  • G to T, chromosome 12 at 85,123,811 bp (GRCm38)
  • C to T, chromosome 15 at 44,529,578 bp (GRCm38)
  • T to C, chromosome 15 at 82,044,017 bp (GRCm38)
  • T to C, chromosome 15 at 99,077,563 bp (GRCm38)
  • A to G, chromosome 17 at 86,797,117 bp (GRCm38)
  • C to T, chromosome 18 at 20,397,947 bp (GRCm38)
  • C to T, chromosome 18 at 62,922,660 bp (GRCm38)
  • A to G, chromosome 18 at 90,539,944 bp (GRCm38)
  • A to G, chromosome 19 at 46,134,068 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9319 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069132-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.